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The map label for this gene is ilvH [H]

Identifier: 238923629

GI number: 238923629

Start: 1148485

End: 1148997

Strand: Direct

Name: ilvH [H]

Synonym: EUBREC_1251

Alternate gene names: 238923629

Gene position: 1148485-1148997 (Clockwise)

Preceding gene: 238923628

Following gene: 238923632

Centisome position: 33.29

GC content: 43.47

Gene sequence:

>513_bases
ATGAATAATATTGAAATGAAAAACAGATGGATTGCACTTTATGTTGAGAATGAGGTCGGTGTTTTAGCAAAGGTTTCAGG
ACTTTTCTCTGCAAAATCCTACAATTTACAGTCTCTTACGGTTGGAACAACAGAGGATGAGACTATTTCCAGAATGACTA
TTTGCGTTACAAGCGATGATATTACCTTTGAGCAGATAAAAAAGCAGCTCAACAGAATGGTCGAGGTCATCAAGGTTATT
GACCTGACTGATGTGCCTCTGCATATGAAGGAAATACTCTATGTCAGGGTATCAAAGCTCACCCGCGAGGAAATTACTGA
TATCTTCCAGACAGCGCAGGTTTTTAATATTGATGTGGTGGACAAGAATGCCGACAGCGTGATCTTAGAGAGCAAGCTCA
CAGAGCACCGCAATGATGATCTTATAGCCCTGCTCAAGTCACAGTACAAGCATATCTCGGTTGTGCGCGGTGGTGCCGTG
GCCATTGAAGCTATGAGTACCGGCTGCCGCTAG

Upstream 100 bases:

>100_bases
AATTATTGAGTTTATGATAGCTACGGATGAGATTGTTCTTCCAATGGTCAAGAGCGGAAATCCTATGAGCGAAATGATTT
TAAAGTAGGAGGTGCAGAAG

Downstream 100 bases:

>100_bases
ATTATATATAGAATCTTGTGACAGTAATGAGGGGACAATTTGTATGTGTTGTTGCACAATGGTAAAATTAGTGTAATATT
AACATAGAGTAAGGGACGAG

Product: IlvH

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MNNIEMKNRWIALYVENEVGVLAKVSGLFSAKSYNLQSLTVGTTEDETISRMTICVTSDDITFEQIKKQLNRMVEVIKVI
DLTDVPLHMKEILYVRVSKLTREEITDIFQTAQVFNIDVVDKNADSVILESKLTEHRNDDLIALLKSQYKHISVVRGGAV
AIEAMSTGCR

Sequences:

>Translated_170_residues
MNNIEMKNRWIALYVENEVGVLAKVSGLFSAKSYNLQSLTVGTTEDETISRMTICVTSDDITFEQIKKQLNRMVEVIKVI
DLTDVPLHMKEILYVRVSKLTREEITDIFQTAQVFNIDVVDKNADSVILESKLTEHRNDDLIALLKSQYKHISVVRGGAV
AIEAMSTGCR
>Mature_170_residues
MNNIEMKNRWIALYVENEVGVLAKVSGLFSAKSYNLQSLTVGTTEDETISRMTICVTSDDITFEQIKKQLNRMVEVIKVI
DLTDVPLHMKEILYVRVSKLTREEITDIFQTAQVFNIDVVDKNADSVILESKLTEHRNDDLIALLKSQYKHISVVRGGAV
AIEAMSTGCR

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=157, Percent_Identity=33.1210191082803, Blast_Score=91, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6319837, Length=103, Percent_Identity=35.9223300970874, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 19208; Mature: 19208

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIEMKNRWIALYVENEVGVLAKVSGLFSAKSYNLQSLTVGTTEDETISRMTICVTSDD
CCCCCCCCCEEEEEEECCCCEEHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEECCC
ITFEQIKKQLNRMVEVIKVIDLTDVPLHMKEILYVRVSKLTREEITDIFQTAQVFNIDVV
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
DKNADSVILESKLTEHRNDDLIALLKSQYKHISVVRGGAVAIEAMSTGCR
ECCCCCEEEHHHHHHCCCCHHHHHHHHHCCEEEEEECCEEEEEECCCCCC
>Mature Secondary Structure
MNNIEMKNRWIALYVENEVGVLAKVSGLFSAKSYNLQSLTVGTTEDETISRMTICVTSDD
CCCCCCCCCEEEEEEECCCCEEHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEECCC
ITFEQIKKQLNRMVEVIKVIDLTDVPLHMKEILYVRVSKLTREEITDIFQTAQVFNIDVV
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
DKNADSVILESKLTEHRNDDLIALLKSQYKHISVVRGGAVAIEAMSTGCR
ECCCCCEEEHHHHHHCCCCHHHHHHHHHCCEEEEEECCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]