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The map label for this gene is hdhA [C]

Identifier: 238923596

GI number: 238923596

Start: 1121266

End: 1121436

Strand: Direct

Name: hdhA [C]

Synonym: EUBREC_1218

Alternate gene names: 238923596

Gene position: 1121266-1121436 (Clockwise)

Preceding gene: 238923595

Following gene: 238923597

Centisome position: 32.5

GC content: 39.77

Gene sequence:

>171_bases
ATGATGAAAGCTGTGCCAAAGGAAGTTATCGAACCTATGATTGAAAGAATTCCATTGCGTCGTCTTGGACAGCCAGAAGA
TATTGCCAATGCGTTTGTGTTTCTTGCATCAGATGAGGCGAGTTACATTACAGGTGTTATATTAAGTGTAGATGGTATGG
CAAGAAGTTAA

Upstream 100 bases:

>100_bases
CTTATAATGTAGCTACAAATTAAGTAAGGAGGTAGCAAGAGAACTAGGACCTAAAGGTATTCGTGTTAATGCTGTTGCAC
CTGGGATTACAGAAACTGAT

Downstream 100 bases:

>100_bases
TTTAATGTGGTATGGTGATGTAATCACGGAAAACAAATGAATTTAAGACTATAACAAAGCTACAAAAAGAAAAAGATAAG
GAGGACTGTAAAATGTCAGC

Product: hypothetical 3-oxoacyl-[acyl-carrier protein] reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: 7-Alpha-Hydroxysteroid Dehydrogenase; 3-Oxoacyl-ACP Reductase

Number of amino acids: Translated: 56; Mature: 56

Protein sequence:

>56_residues
MMKAVPKEVIEPMIERIPLRRLGQPEDIANAFVFLASDEASYITGVILSVDGMARS

Sequences:

>Translated_56_residues
MMKAVPKEVIEPMIERIPLRRLGQPEDIANAFVFLASDEASYITGVILSVDGMARS
>Mature_56_residues
MMKAVPKEVIEPMIERIPLRRLGQPEDIANAFVFLASDEASYITGVILSVDGMARS

Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.100

Molecular weight: Translated: 6177; Mature: 6177

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKAVPKEVIEPMIERIPLRRLGQPEDIANAFVFLASDEASYITGVILSVDGMARS
CCCCCHHHHHHHHHHHCCHHHCCCCCCCHHEEEEEECCCCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMKAVPKEVIEPMIERIPLRRLGQPEDIANAFVFLASDEASYITGVILSVDGMARS
CCCCCHHHHHHHHHHHCCHHHCCCCCCCHHEEEEEECCCCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA