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The map label for this gene is dapA [H]

Identifier: 238923584

GI number: 238923584

Start: 1112975

End: 1113883

Strand: Direct

Name: dapA [H]

Synonym: EUBREC_1206

Alternate gene names: 238923584

Gene position: 1112975-1113883 (Clockwise)

Preceding gene: 238923583

Following gene: 238923585

Centisome position: 32.26

GC content: 42.24

Gene sequence:

>909_bases
ATGAAACAGACAGAATTAAAAGGAATTATTACACCAATTTTAACACCAATGAACGCAGATGAGAGCATCAACACTGACGA
GCTCAGAACACAGATTGACAGACTTATCGATGGCGGTGTGCACGGAATTTTCCCATTTGGAACAAACGGTGAAGGATATA
TCTTAAATGAAAAAGAAAAATGCGAAGTCCTTGAAGCTGCAATTGATCAGGTAAAAGGAAGAGTACCTGTATATGCTGGA
TCAGGTTGCATTTCAACACAGGATACTATCAGGATGAGCAAGGAGGCAGAAAAGCTCGGAGCTGACGTCCTTTCAATAAT
CACTCCAAGCTTTGCGGTTGCGTCACAGAAGGAGTTATACGATCACTATGTAGAGGTTGCCAAACATGTAGATACTCCAA
TTGTTCTTTACAATATTCCTGCCCGTACAGGAAACAAGCTGCTTCCTGAGACAGTAAAGAAGCTTGCAAAGGATGTTGAC
CTTATCATCGGTGCTAAGGATTCAAGCGGTGACTGGGATAACTTAAAGGCATATATCACAGAGACACGTGAACTTGACAA
GAAGTTCTATGTATTATCAGGAAATGATTCACTCATTCTTCCTGCGTTAAAAGAAGGCGGAGTCGGAGGAATAGCAGGAT
GCTCAAATGTTTATCCACATGTGCTTTCATCCATCTACAACCTTTTCAAAGAGGGCAAGCTTGAGGAGGCAGAGGCAGCA
CAGGATTCTATTGCAAGCTTCAGAGCTGTATTCAAATACGGCAATCCTAACACAGTTGTTAAAAAAGCGGTTGCTATGCT
CGGATATCCTGTTGGCGATTGCAGACGTCCATTCAACTATCTGTGCGATGAGGGTGTGGAAGCGCTTGCAAAGGTATTAA
AAGAGAATGCTGACAAAGGAATGAACTAA

Upstream 100 bases:

>100_bases
CAGGTGGGTTCGGAACCAAAGATGTACTGGTAAAGATTGCAGACAAAATATTAAATCAAAAATAAACAAAATTAAACAAG
TTTAAAAGGAGAAGAAAAAC

Downstream 100 bases:

>100_bases
CTCTGGGGAGGATGAATTAATATGAAGTTTGTAATGACACAGGCTGTATGCCCTGAAGGAATGCAGCTTTTAGATGGAAT
AGCTGATGTATATGTAGCTG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKQTELKGIITPILTPMNADESINTDELRTQIDRLIDGGVHGIFPFGTNGEGYILNEKEKCEVLEAAIDQVKGRVPVYAG
SGCISTQDTIRMSKEAEKLGADVLSIITPSFAVASQKELYDHYVEVAKHVDTPIVLYNIPARTGNKLLPETVKKLAKDVD
LIIGAKDSSGDWDNLKAYITETRELDKKFYVLSGNDSLILPALKEGGVGGIAGCSNVYPHVLSSIYNLFKEGKLEEAEAA
QDSIASFRAVFKYGNPNTVVKKAVAMLGYPVGDCRRPFNYLCDEGVEALAKVLKENADKGMN

Sequences:

>Translated_302_residues
MKQTELKGIITPILTPMNADESINTDELRTQIDRLIDGGVHGIFPFGTNGEGYILNEKEKCEVLEAAIDQVKGRVPVYAG
SGCISTQDTIRMSKEAEKLGADVLSIITPSFAVASQKELYDHYVEVAKHVDTPIVLYNIPARTGNKLLPETVKKLAKDVD
LIIGAKDSSGDWDNLKAYITETRELDKKFYVLSGNDSLILPALKEGGVGGIAGCSNVYPHVLSSIYNLFKEGKLEEAEAA
QDSIASFRAVFKYGNPNTVVKKAVAMLGYPVGDCRRPFNYLCDEGVEALAKVLKENADKGMN
>Mature_302_residues
MKQTELKGIITPILTPMNADESINTDELRTQIDRLIDGGVHGIFPFGTNGEGYILNEKEKCEVLEAAIDQVKGRVPVYAG
SGCISTQDTIRMSKEAEKLGADVLSIITPSFAVASQKELYDHYVEVAKHVDTPIVLYNIPARTGNKLLPETVKKLAKDVD
LIIGAKDSSGDWDNLKAYITETRELDKKFYVLSGNDSLILPALKEGGVGGIAGCSNVYPHVLSSIYNLFKEGKLEEAEAA
QDSIASFRAVFKYGNPNTVVKKAVAMLGYPVGDCRRPFNYLCDEGVEALAKVLKENADKGMN

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=305, Percent_Identity=30.8196721311475, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI13540533, Length=297, Percent_Identity=26.2626262626263, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI87082415, Length=268, Percent_Identity=31.3432835820896, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786463, Length=286, Percent_Identity=32.5174825174825, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1788823, Length=293, Percent_Identity=33.1058020477816, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1789620, Length=239, Percent_Identity=28.0334728033473, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32907; Mature: 32907

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTELKGIITPILTPMNADESINTDELRTQIDRLIDGGVHGIFPFGTNGEGYILNEKEK
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCHHH
CEVLEAAIDQVKGRVPVYAGSGCISTQDTIRMSKEAEKLGADVLSIITPSFAVASQKELY
HHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DHYVEVAKHVDTPIVLYNIPARTGNKLLPETVKKLAKDVDLIIGAKDSSGDWDNLKAYIT
HHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHH
ETRELDKKFYVLSGNDSLILPALKEGGVGGIAGCSNVYPHVLSSIYNLFKEGKLEEAEAA
HHHHHCCEEEEEECCCCEEEECHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
QDSIASFRAVFKYGNPNTVVKKAVAMLGYPVGDCRRPFNYLCDEGVEALAKVLKENADKG
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCC
MN
CC
>Mature Secondary Structure
MKQTELKGIITPILTPMNADESINTDELRTQIDRLIDGGVHGIFPFGTNGEGYILNEKEK
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCEEEECCHHH
CEVLEAAIDQVKGRVPVYAGSGCISTQDTIRMSKEAEKLGADVLSIITPSFAVASQKELY
HHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DHYVEVAKHVDTPIVLYNIPARTGNKLLPETVKKLAKDVDLIIGAKDSSGDWDNLKAYIT
HHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHH
ETRELDKKFYVLSGNDSLILPALKEGGVGGIAGCSNVYPHVLSSIYNLFKEGKLEEAEAA
HHHHHCCEEEEEECCCCEEEECHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
QDSIASFRAVFKYGNPNTVVKKAVAMLGYPVGDCRRPFNYLCDEGVEALAKVLKENADKG
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHCCC
MN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]