Click here to switch to the map view.

The map label for this gene is yesM [H]

Identifier: 238923425

GI number: 238923425

Start: 944239

End: 946005

Strand: Direct

Name: yesM [H]

Synonym: EUBREC_1045

Alternate gene names: 238923425

Gene position: 944239-946005 (Clockwise)

Preceding gene: 238923424

Following gene: 238923426

Centisome position: 27.37

GC content: 40.07

Gene sequence:

>1767_bases
ATGAGAAAATCAATATGGAATGCCATTGAGAGAAAGCTTGATGATTATTCACTCAGAAAAAAATTTTACATATTTTATGT
ACTGTGTGTCATGCTGCCGCTCATAGTGACTGATGCAGTGGTGCTTTCCATCGTAAATAATGCTGAAAAAGAAAGCAGCA
GACATGAAATGTCGAGCATAGCAAGTGCTGTGGGATATAATCTGAGCAGCATGGTCAATAACGCAGGAGAGGCAGCTAAG
AGTATCTATACCAGCAAGCGCATAGATGATTTTATATCAAAGGAATACACAAGCTCTGCTGAGTATGTATCAGAGTATCA
GAGCTTCTTTCAGGATACACTTTTTGAAAACACACTTGGAATGAGCAATATAGTGTTTTTCCTGTATGCTGACAATCCTA
CAATAGTAAATGGCGGAAAAGTAAATGATATGTCTGCTGTAAGAAATACGGATTCTTACAGACTACTGGAGCAGAAGGGA
AGCGGAGGACTTTTTTTTGTATATGAAAAAGGCGGAGCCGGATTGTCAGATGAAAGACGTATGATTTATATGCAAAAGCT
GGATTTTTACTCATCTGATATCGAAAAGGTACTCAAGATAGAGTTTAATTATGGCAGCATGATGCGTACTTTTAAGAATA
TGAATTATGATAATGAAGTGCTTATCTGCCATGGAGATGACATAGTGCTGTCAAATGGGGCCTACAGTGGAATCAACAAA
CCATTTAAGACATTGGAGGCGATTGGGAAAATAAGCGACTCCGTATACAGGCAGCAGCTCTCTTTGTATGGCTGTGATCT
TGATATATATGTGTTTAAGACACGCAGTAATATATGGAGCATGCTTATGCACAATGCACCGATCATTGTTTTTCTGATGC
TTATAAATGTATTCTTTCCACTTTGTCTGGTCAGTATCTTTAACCATTCCTTTACGAGCAGGATATTACAGCTTTCAAAG
GTGTTTAAGTCGGTTGACAGCGAAAAGCTTGTATCTATGACTGACAGGGAGAGCAAAGATGAGATCGGCAGCATGATAAA
AAATTACAACAGGATGGTAAGCCGCACAAATGACCTGATCCAGACTGTATATAAGAATAAGCTAAAAGAGCAGGAGATGC
TTGTAAGTCAGAAAAATGCAGAGCTTCTTGCACTGCACAGCCAGATAAATCCGCACTTTCTGTTTAATGCGCTTGAGAGC
ATACGAATGCACAGTCTGCTTAAAAGGGAAAATGAGACGGCTGATATGGTTGAAAAACTCGCAATCATGCAAAGACAGTA
TGTGGAGTGGGGAAATGATGCTGTAACCGTTGCAAAGGAATGTGAATTTGTAAAAGCCTATCTGGCATTGCAGAAATACC
GGTTTGGCGAGCGGCTGAACTATAACATAGATATAGAAGCAGACTGCATGGAATGTCAGGTGCCAAAACTTACGCTTGTA
ACCTTTGTTGAAAATGCCTGTGTGCATGGCATAGAAAGTAAAGCTGCTCCGGGCTGGATATTTGTGCGTATATTCAAAAA
AGCCGGGTTCATGCATATAGAGGTTGAGGATACAGGCAGCGGAATTGATCCGGATGCTCTTGAAAAAATGAAAAGTAACA
TGAAAAATGCAGATATCGATATGTTAAAGACCGGTGGCAGAGTGGGCGTGATAAATGCCTGCCTGCGTATCAAAATGGTA
ACGGAATCTAAAGCAGTATTTGATGTGGACAGTGAGGAAGGCTGCGGTACGACTGTGATGATAAAAATACCGGAAACATA
TTTATAG

Upstream 100 bases:

>100_bases
TTAATAATAAATATGTTATTTTATAATTAATGATAAGTTAAAACAGACTTTAGGAGCGGGCATATGTCGGCTCCTTTAAG
TGATTTCAGAGGAACTGTTT

Downstream 100 bases:

>100_bases
GAGATTTAAAATGCTTAAAGTATTATTGGTGGATGATGAGCCTTTTATAATACAGGGGCTTAAGGTGATCATTGATTGGG
AAAATGAAGGATTTGAGATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MRKSIWNAIERKLDDYSLRKKFYIFYVLCVMLPLIVTDAVVLSIVNNAEKESSRHEMSSIASAVGYNLSSMVNNAGEAAK
SIYTSKRIDDFISKEYTSSAEYVSEYQSFFQDTLFENTLGMSNIVFFLYADNPTIVNGGKVNDMSAVRNTDSYRLLEQKG
SGGLFFVYEKGGAGLSDERRMIYMQKLDFYSSDIEKVLKIEFNYGSMMRTFKNMNYDNEVLICHGDDIVLSNGAYSGINK
PFKTLEAIGKISDSVYRQQLSLYGCDLDIYVFKTRSNIWSMLMHNAPIIVFLMLINVFFPLCLVSIFNHSFTSRILQLSK
VFKSVDSEKLVSMTDRESKDEIGSMIKNYNRMVSRTNDLIQTVYKNKLKEQEMLVSQKNAELLALHSQINPHFLFNALES
IRMHSLLKRENETADMVEKLAIMQRQYVEWGNDAVTVAKECEFVKAYLALQKYRFGERLNYNIDIEADCMECQVPKLTLV
TFVENACVHGIESKAAPGWIFVRIFKKAGFMHIEVEDTGSGIDPDALEKMKSNMKNADIDMLKTGGRVGVINACLRIKMV
TESKAVFDVDSEEGCGTTVMIKIPETYL

Sequences:

>Translated_588_residues
MRKSIWNAIERKLDDYSLRKKFYIFYVLCVMLPLIVTDAVVLSIVNNAEKESSRHEMSSIASAVGYNLSSMVNNAGEAAK
SIYTSKRIDDFISKEYTSSAEYVSEYQSFFQDTLFENTLGMSNIVFFLYADNPTIVNGGKVNDMSAVRNTDSYRLLEQKG
SGGLFFVYEKGGAGLSDERRMIYMQKLDFYSSDIEKVLKIEFNYGSMMRTFKNMNYDNEVLICHGDDIVLSNGAYSGINK
PFKTLEAIGKISDSVYRQQLSLYGCDLDIYVFKTRSNIWSMLMHNAPIIVFLMLINVFFPLCLVSIFNHSFTSRILQLSK
VFKSVDSEKLVSMTDRESKDEIGSMIKNYNRMVSRTNDLIQTVYKNKLKEQEMLVSQKNAELLALHSQINPHFLFNALES
IRMHSLLKRENETADMVEKLAIMQRQYVEWGNDAVTVAKECEFVKAYLALQKYRFGERLNYNIDIEADCMECQVPKLTLV
TFVENACVHGIESKAAPGWIFVRIFKKAGFMHIEVEDTGSGIDPDALEKMKSNMKNADIDMLKTGGRVGVINACLRIKMV
TESKAVFDVDSEEGCGTTVMIKIPETYL
>Mature_588_residues
MRKSIWNAIERKLDDYSLRKKFYIFYVLCVMLPLIVTDAVVLSIVNNAEKESSRHEMSSIASAVGYNLSSMVNNAGEAAK
SIYTSKRIDDFISKEYTSSAEYVSEYQSFFQDTLFENTLGMSNIVFFLYADNPTIVNGGKVNDMSAVRNTDSYRLLEQKG
SGGLFFVYEKGGAGLSDERRMIYMQKLDFYSSDIEKVLKIEFNYGSMMRTFKNMNYDNEVLICHGDDIVLSNGAYSGINK
PFKTLEAIGKISDSVYRQQLSLYGCDLDIYVFKTRSNIWSMLMHNAPIIVFLMLINVFFPLCLVSIFNHSFTSRILQLSK
VFKSVDSEKLVSMTDRESKDEIGSMIKNYNRMVSRTNDLIQTVYKNKLKEQEMLVSQKNAELLALHSQINPHFLFNALES
IRMHSLLKRENETADMVEKLAIMQRQYVEWGNDAVTVAKECEFVKAYLALQKYRFGERLNYNIDIEADCMECQVPKLTLV
TFVENACVHGIESKAAPGWIFVRIFKKAGFMHIEVEDTGSGIDPDALEKMKSNMKNADIDMLKTGGRVGVINACLRIKMV
TESKAVFDVDSEEGCGTTVMIKIPETYL

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=185, Percent_Identity=36.2162162162162, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788446, Length=163, Percent_Identity=33.1288343558282, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66978; Mature: 66978

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSIWNAIERKLDDYSLRKKFYIFYVLCVMLPLIVTDAVVLSIVNNAEKESSRHEMSSI
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAVGYNLSSMVNNAGEAAKSIYTSKRIDDFISKEYTSSAEYVSEYQSFFQDTLFENTLG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
MSNIVFFLYADNPTIVNGGKVNDMSAVRNTDSYRLLEQKGSGGLFFVYEKGGAGLSDERR
CCCEEEEEECCCCEEECCCCCCCHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCCHH
MIYMQKLDFYSSDIEKVLKIEFNYGSMMRTFKNMNYDNEVLICHGDDIVLSNGAYSGINK
HHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCEEEEECCEEEEECCCCCCCCC
PFKTLEAIGKISDSVYRQQLSLYGCDLDIYVFKTRSNIWSMLMHNAPIIVFLMLINVFFP
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHH
LCLVSIFNHSFTSRILQLSKVFKSVDSEKLVSMTDRESKDEIGSMIKNYNRMVSRTNDLI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
QTVYKNKLKEQEMLVSQKNAELLALHSQINPHFLFNALESIRMHSLLKRENETADMVEKL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AIMQRQYVEWGNDAVTVAKECEFVKAYLALQKYRFGERLNYNIDIEADCMECQVPKLTLV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCCCHHHH
TFVENACVHGIESKAAPGWIFVRIFKKAGFMHIEVEDTGSGIDPDALEKMKSNMKNADID
HHHHHHHHHCCCCCCCCCCEEEEEHHHCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCH
MLKTGGRVGVINACLRIKMVTESKAVFDVDSEEGCGTTVMIKIPETYL
HHHCCCCCHHEEHHHEEEEEECCCEEEECCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRKSIWNAIERKLDDYSLRKKFYIFYVLCVMLPLIVTDAVVLSIVNNAEKESSRHEMSSI
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAVGYNLSSMVNNAGEAAKSIYTSKRIDDFISKEYTSSAEYVSEYQSFFQDTLFENTLG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
MSNIVFFLYADNPTIVNGGKVNDMSAVRNTDSYRLLEQKGSGGLFFVYEKGGAGLSDERR
CCCEEEEEECCCCEEECCCCCCCHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCCCCCHH
MIYMQKLDFYSSDIEKVLKIEFNYGSMMRTFKNMNYDNEVLICHGDDIVLSNGAYSGINK
HHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCEEEEECCEEEEECCCCCCCCC
PFKTLEAIGKISDSVYRQQLSLYGCDLDIYVFKTRSNIWSMLMHNAPIIVFLMLINVFFP
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHH
LCLVSIFNHSFTSRILQLSKVFKSVDSEKLVSMTDRESKDEIGSMIKNYNRMVSRTNDLI
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
QTVYKNKLKEQEMLVSQKNAELLALHSQINPHFLFNALESIRMHSLLKRENETADMVEKL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AIMQRQYVEWGNDAVTVAKECEFVKAYLALQKYRFGERLNYNIDIEADCMECQVPKLTLV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHCCCCCHHHH
TFVENACVHGIESKAAPGWIFVRIFKKAGFMHIEVEDTGSGIDPDALEKMKSNMKNADID
HHHHHHHHHCCCCCCCCCCEEEEEHHHCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCH
MLKTGGRVGVINACLRIKMVTESKAVFDVDSEEGCGTTVMIKIPETYL
HHHCCCCCHHEEHHHEEEEEECCCEEEECCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]