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The map label for this gene is norM [H]

Identifier: 238923399

GI number: 238923399

Start: 917006

End: 918352

Strand: Direct

Name: norM [H]

Synonym: EUBREC_1019

Alternate gene names: 238923399

Gene position: 917006-918352 (Clockwise)

Preceding gene: 238923397

Following gene: 238923400

Centisome position: 26.58

GC content: 47.81

Gene sequence:

>1347_bases
ATGAAGTCAAGAGCAACACAGACCAAAGAACTGGATATGGTGAACGGACCACTCGCAAGGAAGATACTGATTTACTCCAT
ACCGCTCATGTTCTCAAACCTGCTTCAGGTATTTTTCAATATGACGGATGTGGCAGTGGTGGGAAAATTTGCAGGTGCAA
GAGCACTCGGCTCGGTCGGTTCCACGACAATCATCATCACACTCACAACAGGCATACTGCTTGGCATGGGAGGCGGTGTC
AATGCTGTCACGGCACTGCACATGGGAGCAGAGGACTATCAGAGGGTGCATAAGACCGTCCACACATCGGTCATCCTGTG
CTTTATAGCGGGACTTTTACTGTTAGTGGCAGGCATGGCTTTTTCAAAGCCACTGCTTGAAGTGATGAATACAAAGCCTG
AGCTTATAGACGGTGCTACAGCATATCTGATGATATATCTGTGCGGTTCGCCGGCGCTTGCGCTTTATAATTTCGGCAAC
GGTGTGCTGAGCGCAGTGGGAGATACAAAGAGACCTCTCATATACCTGAGTATCTCAGGAATTATCAATATAGTGCTCAA
CCTGTTTTTTGTAATAGTGTGCAGACTCGGAGTGATAGGAGTTGCCATCGCAAGCATCATAGCACAGTATATCTCAGCGG
CACTCATTATCAGGTTTCTCATGAAGACATACGGCAGCTACGGCCTGCGCATGAAGGATATAGCGATTGACAGGGATGCA
GCTGCAGCAGTGCTTCGGATTGGAGTGCCGGCTGCGATACAGTACTCGCTCTTTGCCATAGCCAACATATGTATCCAGAC
ATCCATCAACTCCTTCAGCCATGTGGTCGTGGAGGGCAATTCAGCCGCCACCAATGCGGATTCGCTCATCTATGACATGA
TGGCGGCATTTTACACCGCTTGCACCAGCTTCATAGCTCAGAATCTGGGCGCAAGAAAAAAAGAAAGAGTGCTGAGAACA
TTTTTCATCACACTTGCATACTCGTTTCTGATGGGACTGGTGCTTGGAGTGGCATTGTTTATATTCCAAAGACCGTTCCT
TTTGCTCTTTACGAGTGATGATGCCGTGATACACTATGGACAGATCAGAATTGGTGTGATGGCATTCGTCTACTGTGTAT
CAGCCTTCATGGACAATGCCACAGCCGCCGCCAGGGGCATCGGAAAAAGTGTAGCACCTACCATCATAGTGGTTATGGGC
TCTGTCGTATTCAGGATTATATGGCTGCTCACGGTGTTTGCGTATTTTAAGACACTGCAGTCCTTATATCTCATATACGT
CATTTCGTGGACGCTCACCGCAATCGCCGGCAATATATACTTTGCGTACCACTATAGGAGAATTTAG

Upstream 100 bases:

>100_bases
GTAAACAACAGTCTTGAAAAAAGAATGAAACGTATCTATAATTAGAGTACTGTTCACATGGCAGTGTTAATATATAATTA
TAGATTTACAAGAGGGAAAA

Downstream 100 bases:

>100_bases
CGGACAGCTATAATAAAACTGAATAGTAAGCGATAAGAACAGTCAGACATATGTGAGAGATGTGCCCGGCTGTTTTTGCG
GTTTCGCGGCTGTCTCTCTT

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKSRATQTKELDMVNGPLARKILIYSIPLMFSNLLQVFFNMTDVAVVGKFAGARALGSVGSTTIIITLTTGILLGMGGGV
NAVTALHMGAEDYQRVHKTVHTSVILCFIAGLLLLVAGMAFSKPLLEVMNTKPELIDGATAYLMIYLCGSPALALYNFGN
GVLSAVGDTKRPLIYLSISGIINIVLNLFFVIVCRLGVIGVAIASIIAQYISAALIIRFLMKTYGSYGLRMKDIAIDRDA
AAAVLRIGVPAAIQYSLFAIANICIQTSINSFSHVVVEGNSAATNADSLIYDMMAAFYTACTSFIAQNLGARKKERVLRT
FFITLAYSFLMGLVLGVALFIFQRPFLLLFTSDDAVIHYGQIRIGVMAFVYCVSAFMDNATAAARGIGKSVAPTIIVVMG
SVVFRIIWLLTVFAYFKTLQSLYLIYVISWTLTAIAGNIYFAYHYRRI

Sequences:

>Translated_448_residues
MKSRATQTKELDMVNGPLARKILIYSIPLMFSNLLQVFFNMTDVAVVGKFAGARALGSVGSTTIIITLTTGILLGMGGGV
NAVTALHMGAEDYQRVHKTVHTSVILCFIAGLLLLVAGMAFSKPLLEVMNTKPELIDGATAYLMIYLCGSPALALYNFGN
GVLSAVGDTKRPLIYLSISGIINIVLNLFFVIVCRLGVIGVAIASIIAQYISAALIIRFLMKTYGSYGLRMKDIAIDRDA
AAAVLRIGVPAAIQYSLFAIANICIQTSINSFSHVVVEGNSAATNADSLIYDMMAAFYTACTSFIAQNLGARKKERVLRT
FFITLAYSFLMGLVLGVALFIFQRPFLLLFTSDDAVIHYGQIRIGVMAFVYCVSAFMDNATAAARGIGKSVAPTIIVVMG
SVVFRIIWLLTVFAYFKTLQSLYLIYVISWTLTAIAGNIYFAYHYRRI
>Mature_448_residues
MKSRATQTKELDMVNGPLARKILIYSIPLMFSNLLQVFFNMTDVAVVGKFAGARALGSVGSTTIIITLTTGILLGMGGGV
NAVTALHMGAEDYQRVHKTVHTSVILCFIAGLLLLVAGMAFSKPLLEVMNTKPELIDGATAYLMIYLCGSPALALYNFGN
GVLSAVGDTKRPLIYLSISGIINIVLNLFFVIVCRLGVIGVAIASIIAQYISAALIIRFLMKTYGSYGLRMKDIAIDRDA
AAAVLRIGVPAAIQYSLFAIANICIQTSINSFSHVVVEGNSAATNADSLIYDMMAAFYTACTSFIAQNLGARKKERVLRT
FFITLAYSFLMGLVLGVALFIFQRPFLLLFTSDDAVIHYGQIRIGVMAFVYCVSAFMDNATAAARGIGKSVAPTIIVVMG
SVVFRIIWLLTVFAYFKTLQSLYLIYVISWTLTAIAGNIYFAYHYRRI

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48636; Mature: 48636

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00177 TOPOISOMERASE_II ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRATQTKELDMVNGPLARKILIYSIPLMFSNLLQVFFNMTDVAVVGKFAGARALGSVG
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
STTIIITLTTGILLGMGGGVNAVTALHMGAEDYQRVHKTVHTSVILCFIAGLLLLVAGMA
CCEEEEEEHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSKPLLEVMNTKPELIDGATAYLMIYLCGSPALALYNFGNGVLSAVGDTKRPLIYLSISG
HHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEEEHHH
IINIVLNLFFVIVCRLGVIGVAIASIIAQYISAALIIRFLMKTYGSYGLRMKDIAIDRDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHEEECCHH
AAAVLRIGVPAAIQYSLFAIANICIQTSINSFSHVVVEGNSAATNADSLIYDMMAAFYTA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
CTSFIAQNLGARKKERVLRTFFITLAYSFLMGLVLGVALFIFQRPFLLLFTSDDAVIHYG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEC
QIRIGVMAFVYCVSAFMDNATAAARGIGKSVAPTIIVVMGSVVFRIIWLLTVFAYFKTLQ
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYLIYVISWTLTAIAGNIYFAYHYRRI
HHHHHHHHHHHHHHHHCCEEEEEEEECC
>Mature Secondary Structure
MKSRATQTKELDMVNGPLARKILIYSIPLMFSNLLQVFFNMTDVAVVGKFAGARALGSVG
CCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
STTIIITLTTGILLGMGGGVNAVTALHMGAEDYQRVHKTVHTSVILCFIAGLLLLVAGMA
CCEEEEEEHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSKPLLEVMNTKPELIDGATAYLMIYLCGSPALALYNFGNGVLSAVGDTKRPLIYLSISG
HHHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCCCEEEEEHHH
IINIVLNLFFVIVCRLGVIGVAIASIIAQYISAALIIRFLMKTYGSYGLRMKDIAIDRDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHEEECCHH
AAAVLRIGVPAAIQYSLFAIANICIQTSINSFSHVVVEGNSAATNADSLIYDMMAAFYTA
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
CTSFIAQNLGARKKERVLRTFFITLAYSFLMGLVLGVALFIFQRPFLLLFTSDDAVIHYG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEC
QIRIGVMAFVYCVSAFMDNATAAARGIGKSVAPTIIVVMGSVVFRIIWLLTVFAYFKTLQ
HHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLYLIYVISWTLTAIAGNIYFAYHYRRI
HHHHHHHHHHHHHHHHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]