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The map label for this gene is asnC [H]

Identifier: 238923388

GI number: 238923388

Start: 906498

End: 907889

Strand: Direct

Name: asnC [H]

Synonym: EUBREC_1008

Alternate gene names: 238923388

Gene position: 906498-907889 (Clockwise)

Preceding gene: 238923387

Following gene: 238923389

Centisome position: 26.28

GC content: 44.32

Gene sequence:

>1392_bases
ATGGAACTTACAAACATACGCGAGATTTTCCGCAACAAGGACAAATTCGCTGACAAAGAGGTGACTATCGGAGGATGGGT
CAGAAGCAATCGTAATTCAAAGAATTTTGGATTTATCGTGGTAAACGATGGTACATTTTTTGAGCCAATCCAGGTTGTAT
ACGGAAATGGCTTAGACAACTATGATGAGGTTGGCAAGATCAATGTCGGAGCTGCAATTATCGTAAGAGGTACACTTGTG
CTTACTCCGGATGCAAAGCAGCCATTTGAGATTCAAGCCGCAGAGGTGACTGTTGAGGGGGCATCCACACCGGATTATCC
TCTGCAGAAGAAGAGACATACATTTGAGTATCTTCGTACAATCTCACACTTAAGACCTCGTACAAATACTTTTGAGGCAG
TTTTCAGGGTGCGCTCACTCTGCGCATATGCTATTCACAAATTCTTCCAGGAGAGGGATTTTGTGTACGTGCACACACCG
CTTATCACAGGAAGTGACTGTGAGGGTGCAGGAGAGATGTTCCAGGTGACCACACTTGATTTGAACAATCTCCCTATGAC
AGAGGAAGGAAAGGTGGATTTCTCAAAGGATTTCTTTAATAAGCCTACCAACCTTACTGTTTCAGGACAGTTAAACGGCG
AGACATATGCTATGGCATTCAAGAATATCTACACCTTCGGACCTACCTTCCGTGCGGAGAATTCAAACACCACACGTCAT
GCGGCAGAGTTCTGGATGATTGAGCCTGAGATTGCTTTTGCAGACCTTGAGGATGATATGATGCTTGCAGAGAGCATGCT
CAAGTATGTTATCAGCTATGTGCTTGAAAATGCACCTGAGGAGATGGCATTTTTCAACAATTTCGTGGACAAGGGACTCC
TTGACAGATTAAGAAATGTTGTTGAAAATGATTTTGCCCGTGTGACATACACAGAGGCTATCGACATCCTTTCAAAGCAC
AATGACAAGTTTGATTACAAGGTATCATGGGGCTGTGATTTACAGACAGAGCATGAGAGATACCTTACAGAGCAGATTTA
TAAGCGCCCTGTATTTGTCACAGATTATCCGAAGGAGATAAAGGCCTTCTACATGAAGCTGAATGACGACGGAAAGACCG
TTGCAGCAGTTGACTGTCTTGTACCGGGAATCGGAGAAATCATCGGTGGAAGCCAGAGAGAGGATGACTACGACAAGCTC
CTTGCCAGAATAAATGAGCTTGGACTTTCAGAGGATGACTACAAGTTCTACCTTGACTTAAGAAAATACGGCTCTGCAAG
ACACGCGGGCTTTGGATTGGGCTTTGAGAGATGCGTAATGTATCTTACCGGCATGGGCAATATCCGTGACGTTATCCCAT
TCCCTAGAACAGTTAATAACTGTGAGCTGTAA

Upstream 100 bases:

>100_bases
GCAGCGCCGGATACTTCAAGTGGCAGCGCGGATGCCGAATAATAACGATAAATATGCTGTCTGTGGTGATGCGCAGGTAG
CTTAAATGGAGGATTAGATA

Downstream 100 bases:

>100_bases
TCACGAATGAATTTCATACATGAATAATTACCGCCCTTTGCACATATATATGATGTGTGGAGGGCGTTTTTATGTGGAGA
AAAATCAAAGGTCCTGTGAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MELTNIREIFRNKDKFADKEVTIGGWVRSNRNSKNFGFIVVNDGTFFEPIQVVYGNGLDNYDEVGKINVGAAIIVRGTLV
LTPDAKQPFEIQAAEVTVEGASTPDYPLQKKRHTFEYLRTISHLRPRTNTFEAVFRVRSLCAYAIHKFFQERDFVYVHTP
LITGSDCEGAGEMFQVTTLDLNNLPMTEEGKVDFSKDFFNKPTNLTVSGQLNGETYAMAFKNIYTFGPTFRAENSNTTRH
AAEFWMIEPEIAFADLEDDMMLAESMLKYVISYVLENAPEEMAFFNNFVDKGLLDRLRNVVENDFARVTYTEAIDILSKH
NDKFDYKVSWGCDLQTEHERYLTEQIYKRPVFVTDYPKEIKAFYMKLNDDGKTVAAVDCLVPGIGEIIGGSQREDDYDKL
LARINELGLSEDDYKFYLDLRKYGSARHAGFGLGFERCVMYLTGMGNIRDVIPFPRTVNNCEL

Sequences:

>Translated_463_residues
MELTNIREIFRNKDKFADKEVTIGGWVRSNRNSKNFGFIVVNDGTFFEPIQVVYGNGLDNYDEVGKINVGAAIIVRGTLV
LTPDAKQPFEIQAAEVTVEGASTPDYPLQKKRHTFEYLRTISHLRPRTNTFEAVFRVRSLCAYAIHKFFQERDFVYVHTP
LITGSDCEGAGEMFQVTTLDLNNLPMTEEGKVDFSKDFFNKPTNLTVSGQLNGETYAMAFKNIYTFGPTFRAENSNTTRH
AAEFWMIEPEIAFADLEDDMMLAESMLKYVISYVLENAPEEMAFFNNFVDKGLLDRLRNVVENDFARVTYTEAIDILSKH
NDKFDYKVSWGCDLQTEHERYLTEQIYKRPVFVTDYPKEIKAFYMKLNDDGKTVAAVDCLVPGIGEIIGGSQREDDYDKL
LARINELGLSEDDYKFYLDLRKYGSARHAGFGLGFERCVMYLTGMGNIRDVIPFPRTVNNCEL
>Mature_463_residues
MELTNIREIFRNKDKFADKEVTIGGWVRSNRNSKNFGFIVVNDGTFFEPIQVVYGNGLDNYDEVGKINVGAAIIVRGTLV
LTPDAKQPFEIQAAEVTVEGASTPDYPLQKKRHTFEYLRTISHLRPRTNTFEAVFRVRSLCAYAIHKFFQERDFVYVHTP
LITGSDCEGAGEMFQVTTLDLNNLPMTEEGKVDFSKDFFNKPTNLTVSGQLNGETYAMAFKNIYTFGPTFRAENSNTTRH
AAEFWMIEPEIAFADLEDDMMLAESMLKYVISYVLENAPEEMAFFNNFVDKGLLDRLRNVVENDFARVTYTEAIDILSKH
NDKFDYKVSWGCDLQTEHERYLTEQIYKRPVFVTDYPKEIKAFYMKLNDDGKTVAAVDCLVPGIGEIIGGSQREDDYDKL
LARINELGLSEDDYKFYLDLRKYGSARHAGFGLGFERCVMYLTGMGNIRDVIPFPRTVNNCEL

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=452, Percent_Identity=44.4690265486726, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI4758762, Length=458, Percent_Identity=27.7292576419214, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI45439306, Length=352, Percent_Identity=28.125, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1787161, Length=448, Percent_Identity=58.9285714285714, Blast_Score=536, Evalue=1e-153,
Organism=Escherichia coli, GI1790571, Length=472, Percent_Identity=24.364406779661, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789256, Length=373, Percent_Identity=25.4691689008043, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788173, Length=105, Percent_Identity=38.0952380952381, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17556372, Length=438, Percent_Identity=34.703196347032, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI71984122, Length=454, Percent_Identity=30.1762114537445, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17551876, Length=484, Percent_Identity=25.2066115702479, Blast_Score=108, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=482, Percent_Identity=39.4190871369295, Blast_Score=329, Evalue=4e-91,
Organism=Saccharomyces cerevisiae, GI6321807, Length=459, Percent_Identity=29.1938997821351, Blast_Score=193, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6323011, Length=340, Percent_Identity=30.2941176470588, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19922416, Length=449, Percent_Identity=35.1893095768374, Blast_Score=258, Evalue=5e-69,
Organism=Drosophila melanogaster, GI19921528, Length=464, Percent_Identity=27.3706896551724, Blast_Score=161, Evalue=1e-39,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52992; Mature: 52992

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELTNIREIFRNKDKFADKEVTIGGWVRSNRNSKNFGFIVVNDGTFFEPIQVVYGNGLDN
CCCHHHHHHHCCCHHCCCCEEEEECEEECCCCCCCEEEEEECCCCCCCCCCEEECCCCCC
YDEVGKINVGAAIIVRGTLVLTPDAKQPFEIQAAEVTVEGASTPDYPLQKKRHTFEYLRT
CHHCCEEECCEEEEEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
ISHLRPRTNTFEAVFRVRSLCAYAIHKFFQERDFVYVHTPLITGSDCEGAGEMFQVTTLD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEECCCCCCCCCEEEEEEEE
LNNLPMTEEGKVDFSKDFFNKPTNLTVSGQLNGETYAMAFKNIYTFGPTFRAENSNTTRH
CCCCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCEEEEEEHHHHCCCCEEECCCCCCCHH
AAEFWMIEPEIAFADLEDDMMLAESMLKYVISYVLENAPEEMAFFNNFVDKGLLDRLRNV
HHEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VENDFARVTYTEAIDILSKHNDKFDYKVSWGCDLQTEHERYLTEQIYKRPVFVTDYPKEI
HHHHHHEEEHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCEEEECCHHHH
KAFYMKLNDDGKTVAAVDCLVPGIGEIIGGSQREDDYDKLLARINELGLSEDDYKFYLDL
EEEEEEECCCCCEEEEHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEH
RKYGSARHAGFGLGFERCVMYLTGMGNIRDVIPFPRTVNNCEL
HHCCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure
MELTNIREIFRNKDKFADKEVTIGGWVRSNRNSKNFGFIVVNDGTFFEPIQVVYGNGLDN
CCCHHHHHHHCCCHHCCCCEEEEECEEECCCCCCCEEEEEECCCCCCCCCCEEECCCCCC
YDEVGKINVGAAIIVRGTLVLTPDAKQPFEIQAAEVTVEGASTPDYPLQKKRHTFEYLRT
CHHCCEEECCEEEEEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
ISHLRPRTNTFEAVFRVRSLCAYAIHKFFQERDFVYVHTPLITGSDCEGAGEMFQVTTLD
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEECCCCCCCCCEEEEEEEE
LNNLPMTEEGKVDFSKDFFNKPTNLTVSGQLNGETYAMAFKNIYTFGPTFRAENSNTTRH
CCCCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCEEEEEEHHHHCCCCEEECCCCCCCHH
AAEFWMIEPEIAFADLEDDMMLAESMLKYVISYVLENAPEEMAFFNNFVDKGLLDRLRNV
HHEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VENDFARVTYTEAIDILSKHNDKFDYKVSWGCDLQTEHERYLTEQIYKRPVFVTDYPKEI
HHHHHHEEEHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCEEEECCHHHH
KAFYMKLNDDGKTVAAVDCLVPGIGEIIGGSQREDDYDKLLARINELGLSEDDYKFYLDL
EEEEEEECCCCCEEEEHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEH
RKYGSARHAGFGLGFERCVMYLTGMGNIRDVIPFPRTVNNCEL
HHCCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA