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The map label for this gene is tig [H]

Identifier: 238923387

GI number: 238923387

Start: 905180

End: 906439

Strand: Direct

Name: tig [H]

Synonym: EUBREC_1007

Alternate gene names: 238923387

Gene position: 905180-906439 (Clockwise)

Preceding gene: 238923386

Following gene: 238923388

Centisome position: 26.24

GC content: 44.6

Gene sequence:

>1260_bases
ATGAGTGAGAAGAAGAATACAGGTAAGAAGGCAGTCATAGCAGTGATTGTGATTGCACTTATCGTGGTAATTATTGCGCT
TGTTGCTGTGATAAGCGGCAAGAGCAAAAAGGGTGGCTCAAAGAGCGCAACAGAGTCTGGCACCGAGGCCGGCAGCGAGA
CGATGCGAAGCGGACAGTTTGACATAGACTACGCAAAGCAGGTTACAAAGCTTGCAGACTATTCAGGTGTTGCAATTACT
GTCTCAAACGATTATGAGATAAACGATACAGCAAAGCAGACATATCTGACCAATGTGCTTCAGTCATATGGTGCAGATGC
GTACAAGCAGGTTACAGATCGTGATACAGTTGCAGATGGCGATTATGTCAAGGTTGATTACACAGGATATAAGGATGGCA
AAGCATTTGATGGTGGCTCAGCTACAGATGTGATGCTTGATGTGACAAATAACAGCCAGGTCGGCGGTTCATCATTTATC
GATGGATTTACAAAGCCTTTAATCGGAGCCAAGGTGGGTGACAAGGTTAAGGGTGACGTGACATTCCCTGAGGATTATGG
CAACGATGACCTAAACGGACATACAGTTACATTTGAGTATACAGTAAAGGGCATTTACTCAGCAGATCCTGTTGCACTTG
CTGATATGACAGACGAGCAGGTCAACACAGTGTTTGGAAAGGCCGGAGTGACAACAAATGCCCAGCTTACCACACAGATT
GAGAAAGATTTGAAGCAGCAGCTCTACAGCGCTGAGGTGGACAAGATAAAGAGCTACATGATTGACAACAGCACAGTTGA
GATTCCTGATGAGTATCTACAGGCCAGACTCAATGAGTATATTGCTTCATTTACCAAGGAAAATGTCAAGGATGGACAGA
CACTTAAGAAATATTTAAAGTCCAACTACAACATGACAGTGGATCAGGCCACAGAGAAGTGGAAGGAGAATCTGACAGAC
CAGATAAAGACAGAGTTCATCTTTGGGCTTATCGCTGAGAAGGAAAATATCAAGATGGATGATGATGCCTTCAACAGCTA
TGTGGATTACATCGTATCAGCCAGCAATGGCCAGTTCAGCAAGGCTTCTGAGGTATACAAGTATTTTGGAAGCGGACACA
AGGATGAGGGAAAGACATACCTTAAGAACCAGTACCTTGTAAACAAGGCTATTGATACAGTCACAGAGAAAGCAAATGTG
ACATTTGAGGATGGCAGTGCAGCGCCGGATACTTCAAGTGGCAGCGCGGATGCCGAATAA

Upstream 100 bases:

>100_bases
TGATATTGTAGACAGGTATAGTGTTTTGCGGATGCGTTTTTGCCGTGGCAGGGCATTGTACTTATAAATAACATGACTTA
CAGATTTCAGGAGGATTCCA

Downstream 100 bases:

>100_bases
TAACGATAAATATGCTGTCTGTGGTGATGCGCAGGTAGCTTAAATGGAGGATTAGATAATGGAACTTACAAACATACGCG
AGATTTTCCGCAACAAGGAC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSEKKNTGKKAVIAVIVIALIVVIIALVAVISGKSKKGGSKSATESGTEAGSETMRSGQFDIDYAKQVTKLADYSGVAIT
VSNDYEINDTAKQTYLTNVLQSYGADAYKQVTDRDTVADGDYVKVDYTGYKDGKAFDGGSATDVMLDVTNNSQVGGSSFI
DGFTKPLIGAKVGDKVKGDVTFPEDYGNDDLNGHTVTFEYTVKGIYSADPVALADMTDEQVNTVFGKAGVTTNAQLTTQI
EKDLKQQLYSAEVDKIKSYMIDNSTVEIPDEYLQARLNEYIASFTKENVKDGQTLKKYLKSNYNMTVDQATEKWKENLTD
QIKTEFIFGLIAEKENIKMDDDAFNSYVDYIVSASNGQFSKASEVYKYFGSGHKDEGKTYLKNQYLVNKAIDTVTEKANV
TFEDGSAAPDTSSGSADAE

Sequences:

>Translated_419_residues
MSEKKNTGKKAVIAVIVIALIVVIIALVAVISGKSKKGGSKSATESGTEAGSETMRSGQFDIDYAKQVTKLADYSGVAIT
VSNDYEINDTAKQTYLTNVLQSYGADAYKQVTDRDTVADGDYVKVDYTGYKDGKAFDGGSATDVMLDVTNNSQVGGSSFI
DGFTKPLIGAKVGDKVKGDVTFPEDYGNDDLNGHTVTFEYTVKGIYSADPVALADMTDEQVNTVFGKAGVTTNAQLTTQI
EKDLKQQLYSAEVDKIKSYMIDNSTVEIPDEYLQARLNEYIASFTKENVKDGQTLKKYLKSNYNMTVDQATEKWKENLTD
QIKTEFIFGLIAEKENIKMDDDAFNSYVDYIVSASNGQFSKASEVYKYFGSGHKDEGKTYLKNQYLVNKAIDTVTEKANV
TFEDGSAAPDTSSGSADAE
>Mature_418_residues
SEKKNTGKKAVIAVIVIALIVVIIALVAVISGKSKKGGSKSATESGTEAGSETMRSGQFDIDYAKQVTKLADYSGVAITV
SNDYEINDTAKQTYLTNVLQSYGADAYKQVTDRDTVADGDYVKVDYTGYKDGKAFDGGSATDVMLDVTNNSQVGGSSFID
GFTKPLIGAKVGDKVKGDVTFPEDYGNDDLNGHTVTFEYTVKGIYSADPVALADMTDEQVNTVFGKAGVTTNAQLTTQIE
KDLKQQLYSAEVDKIKSYMIDNSTVEIPDEYLQARLNEYIASFTKENVKDGQTLKKYLKSNYNMTVDQATEKWKENLTDQ
IKTEFIFGLIAEKENIKMDDDAFNSYVDYIVSASNGQFSKASEVYKYFGSGHKDEGKTYLKNQYLVNKAIDTVTEKANVT
FEDGSAAPDTSSGSADAE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=289, Percent_Identity=23.8754325259516, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 45631; Mature: 45500

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKKNTGKKAVIAVIVIALIVVIIALVAVISGKSKKGGSKSATESGTEAGSETMRSGQF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
DIDYAKQVTKLADYSGVAITVSNDYEINDTAKQTYLTNVLQSYGADAYKQVTDRDTVADG
CHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCC
DYVKVDYTGYKDGKAFDGGSATDVMLDVTNNSQVGGSSFIDGFTKPLIGAKVGDKVKGDV
CEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCE
TFPEDYGNDDLNGHTVTFEYTVKGIYSADPVALADMTDEQVNTVFGKAGVTTNAQLTTQI
ECCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCHHHHHH
EKDLKQQLYSAEVDKIKSYMIDNSTVEIPDEYLQARLNEYIASFTKENVKDGQTLKKYLK
HHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SNYNMTVDQATEKWKENLTDQIKTEFIFGLIAEKENIKMDDDAFNSYVDYIVSASNGQFS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCCCH
KASEVYKYFGSGHKDEGKTYLKNQYLVNKAIDTVTEKANVTFEDGSAAPDTSSGSADAE
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEKKNTGKKAVIAVIVIALIVVIIALVAVISGKSKKGGSKSATESGTEAGSETMRSGQF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
DIDYAKQVTKLADYSGVAITVSNDYEINDTAKQTYLTNVLQSYGADAYKQVTDRDTVADG
CHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCC
DYVKVDYTGYKDGKAFDGGSATDVMLDVTNNSQVGGSSFIDGFTKPLIGAKVGDKVKGDV
CEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCE
TFPEDYGNDDLNGHTVTFEYTVKGIYSADPVALADMTDEQVNTVFGKAGVTTNAQLTTQI
ECCCCCCCCCCCCCEEEEEEEEEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCHHHHHH
EKDLKQQLYSAEVDKIKSYMIDNSTVEIPDEYLQARLNEYIASFTKENVKDGQTLKKYLK
HHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SNYNMTVDQATEKWKENLTDQIKTEFIFGLIAEKENIKMDDDAFNSYVDYIVSASNGQFS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCCCH
KASEVYKYFGSGHKDEGKTYLKNQYLVNKAIDTVTEKANVTFEDGSAAPDTSSGSADAE
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA