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The map label for this gene is tig

Identifier: 238923368

GI number: 238923368

Start: 882348

End: 883679

Strand: Direct

Name: tig

Synonym: EUBREC_0988

Alternate gene names: 238923368

Gene position: 882348-883679 (Clockwise)

Preceding gene: 238923366

Following gene: 238923369

Centisome position: 25.58

GC content: 44.37

Gene sequence:

>1332_bases
ATGAGTGTACAGGTTGAGAATTTAGAGCATAATATGGCGAAGCTTACTATTGAGGTAGCAGCTGAGGAATTAGAGAAAGC
ATTGGATTCTGCATATCAGAAGCAGAAGAAACAGATTAGTGTACCTGGATTCCGTAAAGGAAAAGTGCCAAGAGCTATGA
TTGAGAAAATGTATGGAGCAGGTGTGTTCTACGAGGATGCAGCAAACATTCTTATGCAGCAGACATACGCAGGTGCAGTT
GACGAGAGCGGTGTTGACATTGTTTCACGCCCAACAGTTGAGGTTACTCAGATTGAGAAGGGACAGCCTTTCATCTACAC
AGCAGAGGTTGCTGTAAGACCTGAGGTTACTCTTGGTAAGTACATGGGCGTTACAGTTACAAAGATCGACACATCAGTTT
CTGATGAAGAGGTTGACGCTGAGCTTGAGAACCAGAGAAACAAAAATGCAAGAACAGTTACAGTTACAGATCGTCCTGTA
GCAGAGGGAGATACAGCAGTTATCGACTTTGAGGGATTTGTTGACGGAGTAGCTTTCGAGGGTGGAAAGGGTGAGAATCA
TCCATTAGAGATTGGTTCACACACATTCATCGATACATTCGAGGATCAGTTAGTAGGAAAGAACACAGGCGATGAGGTTG
AGGTCAATGTAACATTCCCTGAGAAGTATCAGGCAGAAGACCTTGCAGGAAAGCCGGCTACATTCAAGGTTAAGATCAAC
GAGATCAAGGCTAAGGAGCTTCCAGAGCTTGATGATGAGTTTGCACAGGATGCAGCAGGTGTTGATACATTAGCTGAGTA
CAAAGAGGAAATCAAAAAGAACCTCACAGAGAAGAAAGAGACAGAAGCTAAGAAGACTAAAGAGGATGAGGCTATCCAGA
AGATTATCGACAAGTCAAAGATGGATCTTCCTGAGGCAATGATTGAGACACAGTGTGAGACAATGGTTGAGGAGTTCGCT
CAGAGAATCGCACAGAGCGGTCTTACAATGGAGCAGTACTTACAGTTCTCAGGCATGACAGTTGACCAGCTTAAGGATCA
GGTTCGTCCTGAGGCTACAACACGTATCCAGAGCAGCCTTGTACTTGAGCAGATTGCCAAGGAGGAAAACATCGAGGTTA
CTGATGCAGATATCGATGCTGAGGTAGAGAAGATGGCTAAGGCATACGGCATGGAGGCTGATAAGCTTAAAGAGTACATG
GGAGATGCTGAGAAGGAGTCTATGAAGAAAGACATTGCTATCACAAAGGCCGTAGATCTTATCATGGACAACGTTAAAGA
GCGTGCAAAGGCAAAGAAAAAGGCTGATGCAGAAGAGTCTACAGAAGAATAA

Upstream 100 bases:

>100_bases
AATCATCCAATGACTGGGCTTAGCAGTTTAAAAAGCATGCCCACATTACATTTGATGTACATACCATTCATATATATTTT
TAAGGAGGATAACGATTGAC

Downstream 100 bases:

>100_bases
GATTTTTGAATCAAGATTTGATTGACTGGCTCAGAAGCCTATTTTCTGAGCCGGTCTTTTGAGCTTTTATAAAGGAGGTA
TTTTATATGAGTTTAGTACC

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSVQVENLEHNMAKLTIEVAAEELEKALDSAYQKQKKQISVPGFRKGKVPRAMIEKMYGAGVFYEDAANILMQQTYAGAV
DESGVDIVSRPTVEVTQIEKGQPFIYTAEVAVRPEVTLGKYMGVTVTKIDTSVSDEEVDAELENQRNKNARTVTVTDRPV
AEGDTAVIDFEGFVDGVAFEGGKGENHPLEIGSHTFIDTFEDQLVGKNTGDEVEVNVTFPEKYQAEDLAGKPATFKVKIN
EIKAKELPELDDEFAQDAAGVDTLAEYKEEIKKNLTEKKETEAKKTKEDEAIQKIIDKSKMDLPEAMIETQCETMVEEFA
QRIAQSGLTMEQYLQFSGMTVDQLKDQVRPEATTRIQSSLVLEQIAKEENIEVTDADIDAEVEKMAKAYGMEADKLKEYM
GDAEKESMKKDIAITKAVDLIMDNVKERAKAKKKADAEESTEE

Sequences:

>Translated_443_residues
MSVQVENLEHNMAKLTIEVAAEELEKALDSAYQKQKKQISVPGFRKGKVPRAMIEKMYGAGVFYEDAANILMQQTYAGAV
DESGVDIVSRPTVEVTQIEKGQPFIYTAEVAVRPEVTLGKYMGVTVTKIDTSVSDEEVDAELENQRNKNARTVTVTDRPV
AEGDTAVIDFEGFVDGVAFEGGKGENHPLEIGSHTFIDTFEDQLVGKNTGDEVEVNVTFPEKYQAEDLAGKPATFKVKIN
EIKAKELPELDDEFAQDAAGVDTLAEYKEEIKKNLTEKKETEAKKTKEDEAIQKIIDKSKMDLPEAMIETQCETMVEEFA
QRIAQSGLTMEQYLQFSGMTVDQLKDQVRPEATTRIQSSLVLEQIAKEENIEVTDADIDAEVEKMAKAYGMEADKLKEYM
GDAEKESMKKDIAITKAVDLIMDNVKERAKAKKKADAEESTEE
>Mature_442_residues
SVQVENLEHNMAKLTIEVAAEELEKALDSAYQKQKKQISVPGFRKGKVPRAMIEKMYGAGVFYEDAANILMQQTYAGAVD
ESGVDIVSRPTVEVTQIEKGQPFIYTAEVAVRPEVTLGKYMGVTVTKIDTSVSDEEVDAELENQRNKNARTVTVTDRPVA
EGDTAVIDFEGFVDGVAFEGGKGENHPLEIGSHTFIDTFEDQLVGKNTGDEVEVNVTFPEKYQAEDLAGKPATFKVKINE
IKAKELPELDDEFAQDAAGVDTLAEYKEEIKKNLTEKKETEAKKTKEDEAIQKIIDKSKMDLPEAMIETQCETMVEEFAQ
RIAQSGLTMEQYLQFSGMTVDQLKDQVRPEATTRIQSSLVLEQIAKEENIEVTDADIDAEVEKMAKAYGMEADKLKEYMG
DAEKESMKKDIAITKAVDLIMDNVKERAKAKKKADAEESTEE

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=390, Percent_Identity=30.5128205128205, Blast_Score=179, Evalue=3e-46,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_EUBR3 (C4ZGF3)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002936884.1
- GeneID:   7964962
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_0988
- ProtClustDB:   CLSK2506060
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 49303; Mature: 49172

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVQVENLEHNMAKLTIEVAAEELEKALDSAYQKQKKQISVPGFRKGKVPRAMIEKMYGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
GVFYEDAANILMQQTYAGAVDESGVDIVSRPTVEVTQIEKGQPFIYTAEVAVRPEVTLGK
CCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEEEEECCCCCEEEEEEEEECCCCCHHH
YMGVTVTKIDTSVSDEEVDAELENQRNKNARTVTVTDRPVAEGDTAVIDFEGFVDGVAFE
HCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEC
GGKGENHPLEIGSHTFIDTFEDQLVGKNTGDEVEVNVTFPEKYQAEDLAGKPATFKVKIN
CCCCCCCCEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCCCCEEEEEEE
EIKAKELPELDDEFAQDAAGVDTLAEYKEEIKKNLTEKKETEAKKTKEDEAIQKIIDKSK
CCCHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDLPEAMIETQCETMVEEFAQRIAQSGLTMEQYLQFSGMTVDQLKDQVRPEATTRIQSSL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHH
VLEQIAKEENIEVTDADIDAEVEKMAKAYGMEADKLKEYMGDAEKESMKKDIAITKAVDL
HHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IMDNVKERAKAKKKADAEESTEE
HHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SVQVENLEHNMAKLTIEVAAEELEKALDSAYQKQKKQISVPGFRKGKVPRAMIEKMYGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
GVFYEDAANILMQQTYAGAVDESGVDIVSRPTVEVTQIEKGQPFIYTAEVAVRPEVTLGK
CCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCEEEEEECCCCCEEEEEEEEECCCCCHHH
YMGVTVTKIDTSVSDEEVDAELENQRNKNARTVTVTDRPVAEGDTAVIDFEGFVDGVAFE
HCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCEEEC
GGKGENHPLEIGSHTFIDTFEDQLVGKNTGDEVEVNVTFPEKYQAEDLAGKPATFKVKIN
CCCCCCCCEECCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCCCCEEEEEEE
EIKAKELPELDDEFAQDAAGVDTLAEYKEEIKKNLTEKKETEAKKTKEDEAIQKIIDKSK
CCCHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDLPEAMIETQCETMVEEFAQRIAQSGLTMEQYLQFSGMTVDQLKDQVRPEATTRIQSSL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHH
VLEQIAKEENIEVTDADIDAEVEKMAKAYGMEADKLKEYMGDAEKESMKKDIAITKAVDL
HHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
IMDNVKERAKAKKKADAEESTEE
HHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA