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The map label for this gene is yajL [H]

Identifier: 238923366

GI number: 238923366

Start: 881222

End: 881767

Strand: Direct

Name: yajL [H]

Synonym: EUBREC_0986

Alternate gene names: 238923366

Gene position: 881222-881767 (Clockwise)

Preceding gene: 238923364

Following gene: 238923368

Centisome position: 25.54

GC content: 47.07

Gene sequence:

>546_bases
ATGATTAAAGTAGGAATTTTTATGGCAGACGGCTGTGAGGAGATTGAAGGACTTACAGTAGTCGATATAGTTAGAAGAGC
AAAGCTTGAGATTGAAACCATATCAATCACGGAAAAAGCCGAGGTGACAAGCTCTCATCAGGTGACATTTAAGACAGATA
CCACAAAGGCACAGGCTGATTTTGACAGCTACGATGCAATCGTACTGCCGGGAGGCATGCCGGGTACATTAAACCTCGGT
GCTGATGAGACCGTAGTAAAGACAATTAAGAGATTCGCCGCTGAGGGAAAGCTTGTTGCAGCGATATGTGCAGCGCCTAG
CGTGCTCGGTGAGAATCATATACTTGAGGGCAAAAAAGCTACCTGTCATCCGGGTTTTGAGGAAAAGCTGCTCGGTGCAC
AGTGGCTTGAGCAGCCTGTAGTTGTGGACGGCAATGTGATTACAAGTCGTGGAATGGGAACAGCTATTGCGTTTGCACTC
GAGCTTGTCAGATACTTCACAGACGATGCCACAGTAGAGCATATTCGACAGGGACTGGTATACTAG

Upstream 100 bases:

>100_bases
CGGTATTTAAAAATTCAAGGACGAACCGCAGCTTTTTATAGTATGATTAAAGGGTCAAAAGGTATCATAGTATTATCAAA
GAAAAATAAAGGAGAAAAAT

Downstream 100 bases:

>100_bases
ACCGGCAAGCCCTGTATTATAACAAAAGAGGTCACACACCAAACCCCATGGTGCGCGGCCTCTTTTTATGCTTGCATTTG
AAGCGTACATTTGAAGCCTG

Product: 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MIKVGIFMADGCEEIEGLTVVDIVRRAKLEIETISITEKAEVTSSHQVTFKTDTTKAQADFDSYDAIVLPGGMPGTLNLG
ADETVVKTIKRFAAEGKLVAAICAAPSVLGENHILEGKKATCHPGFEEKLLGAQWLEQPVVVDGNVITSRGMGTAIAFAL
ELVRYFTDDATVEHIRQGLVY

Sequences:

>Translated_181_residues
MIKVGIFMADGCEEIEGLTVVDIVRRAKLEIETISITEKAEVTSSHQVTFKTDTTKAQADFDSYDAIVLPGGMPGTLNLG
ADETVVKTIKRFAAEGKLVAAICAAPSVLGENHILEGKKATCHPGFEEKLLGAQWLEQPVVVDGNVITSRGMGTAIAFAL
ELVRYFTDDATVEHIRQGLVY
>Mature_181_residues
MIKVGIFMADGCEEIEGLTVVDIVRRAKLEIETISITEKAEVTSSHQVTFKTDTTKAQADFDSYDAIVLPGGMPGTLNLG
ADETVVKTIKRFAAEGKLVAAICAAPSVLGENHILEGKKATCHPGFEEKLLGAQWLEQPVVVDGNVITSRGMGTAIAFAL
ELVRYFTDDATVEHIRQGLVY

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=179, Percent_Identity=32.9608938547486, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI31543380, Length=179, Percent_Identity=32.9608938547486, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI87081736, Length=163, Percent_Identity=35.5828220858896, Blast_Score=94, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17531319, Length=170, Percent_Identity=33.5294117647059, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17558714, Length=154, Percent_Identity=32.4675324675325, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571932, Length=177, Percent_Identity=34.4632768361582, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24653499, Length=179, Percent_Identity=32.9608938547486, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19496; Mature: 19496

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVGIFMADGCEEIEGLTVVDIVRRAKLEIETISITEKAEVTSSHQVTFKTDTTKAQAD
CEEEEEEEECCHHHHCCCHHHHHHHHHHEEEEEEEECCCHHCCCCCEEEEEECCCCCCCC
FDSYDAIVLPGGMPGTLNLGADETVVKTIKRFAAEGKLVAAICAAPSVLGENHILEGKKA
CCCCCEEEECCCCCCEEECCCCHHHHHHHHHHHHCCCEEEHHHHCCHHHCCCCEECCCCC
TCHPGFEEKLLGAQWLEQPVVVDGNVITSRGMGTAIAFALELVRYFTDDATVEHIRQGLV
CCCCCHHHHHHHHHHHCCCEEECCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCC
Y
C
>Mature Secondary Structure
MIKVGIFMADGCEEIEGLTVVDIVRRAKLEIETISITEKAEVTSSHQVTFKTDTTKAQAD
CEEEEEEEECCHHHHCCCHHHHHHHHHHEEEEEEEECCCHHCCCCCEEEEEECCCCCCCC
FDSYDAIVLPGGMPGTLNLGADETVVKTIKRFAAEGKLVAAICAAPSVLGENHILEGKKA
CCCCCEEEECCCCCCEEECCCCHHHHHHHHHHHHCCCEEEHHHHCCHHHCCCCEECCCCC
TCHPGFEEKLLGAQWLEQPVVVDGNVITSRGMGTAIAFALELVRYFTDDATVEHIRQGLV
CCCCCHHHHHHHHHHHCCCEEECCCEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]