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The map label for this gene is trxB [H]

Identifier: 238923282

GI number: 238923282

Start: 799380

End: 800375

Strand: Direct

Name: trxB [H]

Synonym: EUBREC_0893

Alternate gene names: 238923282

Gene position: 799380-800375 (Clockwise)

Preceding gene: 238923281

Following gene: 238923283

Centisome position: 23.17

GC content: 46.29

Gene sequence:

>996_bases
ATGAAAGGAACCAATTCCATGTTTGATATAATAATAATAGGCAGTGGTCCGGCAGGACTGTCTGCAGCAATATATGCAAA
GAGAGCCAATCTGAATGTGGCAATAGCAGAAAAAGAATACGAGGGGACAGGCCAGATAGCCGAGAGCGGAAATGTGAACA
ACTATCTGGGGCTTCCAAACATAAACGGATATGACCTGGGAGAAAAATTCAGGGAGCATGCAGTGTCTCTTGATGTAGAA
TTTATCGAAAAAGAAGCAGTGCAGATAGAAGCAGTGCAAAATGGTGAGAAAGAAGAATCAGCGATATACAGAGTGAAATT
CGATGATGACACGATAGCAGAGGCAAGAGCGCTCATCTATACCGCAGGAGCATATCCGAGAAAGGCAGGAGTGCCGGGAG
AGGATGAGTATACCGGTAAGGGAGTATCTTACTGCGCAATCTGTGACGGAGCATTCTATAAAGGAAAGACAGCCGCAGTG
CTGGGCGGCGGAGATACCGCTTTGGATGATGCATTATATCTGTCCGATATATGTGAGAAGGTCTATCTGGTTCACAGAAG
AGACAGCTTCCGCGGTGCACAGAGCACAGTTGAGCTCTTAAAGCAGAAAGAAAATGTAGAGCTTGTCCTAAACGAAACAG
TGACAGAAATATATGGAGAAAAAAAGCCGACAGGCATAAAGCTTAAAAGTGGCAGGACACTGGCTGTAGACGGAGTATTC
GTGGCATACGGCTCAGTACCGCAGTCAGAGCTTATAAAGAATCTGGTGCAGCTCGATGAGAGAGGATATGTAGTGGCAGG
TGAGGACGGCATCACATATGCTGCAACAAAAAATGGTGACCATGATAGAAGCGTCCAGCCGGGACTGTATGTGGCGGGAG
ATGTCCGTACCAAGACACTGCGTCAGGTGGTAACCGCAGTATCTGACGGAGCAAATGCCGCAACGACAGCCGCAGAGTAT
TTAAGGGACATTAATGGCTATAAACAAAATATATAA

Upstream 100 bases:

>100_bases
ACCGCTTGTTTTTATAAAGGTGTTTTATAAAAGCAGGCGGTATTATTGTATTTTTTAAGGATAATGTATATAATAAGTTA
CCGAAAAAATTCAATGGACG

Downstream 100 bases:

>100_bases
CCACGCACAAATAATTTGTATAACTGATAGCATTGACTTTCAACACACACGTTTGTATAATAATCTCATCAATTCCTAGT
AACACAATAGACTATGTAAG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKGTNSMFDIIIIGSGPAGLSAAIYAKRANLNVAIAEKEYEGTGQIAESGNVNNYLGLPNINGYDLGEKFREHAVSLDVE
FIEKEAVQIEAVQNGEKEESAIYRVKFDDDTIAEARALIYTAGAYPRKAGVPGEDEYTGKGVSYCAICDGAFYKGKTAAV
LGGGDTALDDALYLSDICEKVYLVHRRDSFRGAQSTVELLKQKENVELVLNETVTEIYGEKKPTGIKLKSGRTLAVDGVF
VAYGSVPQSELIKNLVQLDERGYVVAGEDGITYAATKNGDHDRSVQPGLYVAGDVRTKTLRQVVTAVSDGANAATTAAEY
LRDINGYKQNI

Sequences:

>Translated_331_residues
MKGTNSMFDIIIIGSGPAGLSAAIYAKRANLNVAIAEKEYEGTGQIAESGNVNNYLGLPNINGYDLGEKFREHAVSLDVE
FIEKEAVQIEAVQNGEKEESAIYRVKFDDDTIAEARALIYTAGAYPRKAGVPGEDEYTGKGVSYCAICDGAFYKGKTAAV
LGGGDTALDDALYLSDICEKVYLVHRRDSFRGAQSTVELLKQKENVELVLNETVTEIYGEKKPTGIKLKSGRTLAVDGVF
VAYGSVPQSELIKNLVQLDERGYVVAGEDGITYAATKNGDHDRSVQPGLYVAGDVRTKTLRQVVTAVSDGANAATTAAEY
LRDINGYKQNI
>Mature_331_residues
MKGTNSMFDIIIIGSGPAGLSAAIYAKRANLNVAIAEKEYEGTGQIAESGNVNNYLGLPNINGYDLGEKFREHAVSLDVE
FIEKEAVQIEAVQNGEKEESAIYRVKFDDDTIAEARALIYTAGAYPRKAGVPGEDEYTGKGVSYCAICDGAFYKGKTAAV
LGGGDTALDDALYLSDICEKVYLVHRRDSFRGAQSTVELLKQKENVELVLNETVTEIYGEKKPTGIKLKSGRTLAVDGVF
VAYGSVPQSELIKNLVQLDERGYVVAGEDGITYAATKNGDHDRSVQPGLYVAGDVRTKTLRQVVTAVSDGANAATTAAEY
LRDINGYKQNI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=330, Percent_Identity=36.3636363636364, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI87081763, Length=322, Percent_Identity=29.8136645962733, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320560, Length=333, Percent_Identity=30.03003003003, Blast_Score=149, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321898, Length=332, Percent_Identity=30.421686746988, Blast_Score=148, Evalue=1e-36,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35649; Mature: 35649

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGTNSMFDIIIIGSGPAGLSAAIYAKRANLNVAIAEKEYEGTGQIAESGNVNNYLGLPN
CCCCCCEEEEEEEECCCCCCEEEEEEEECCCEEEEEECCCCCCCCEECCCCCCCEECCCC
INGYDLGEKFREHAVSLDVEFIEKEAVQIEAVQNGEKEESAIYRVKFDDDTIAEARALIY
CCCCCHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCHHHHHEEEEE
TAGAYPRKAGVPGEDEYTGKGVSYCAICDGAFYKGKTAAVLGGGDTALDDALYLSDICEK
ECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
VYLVHRRDSFRGAQSTVELLKQKENVELVLNETVTEIYGEKKPTGIKLKSGRTLAVDGVF
HHEEECCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCEEEECCCEEEECEEE
VAYGSVPQSELIKNLVQLDERGYVVAGEDGITYAATKNGDHDRSVQPGLYVAGDVRTKTL
EEECCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEEECCCHHHHH
RQVVTAVSDGANAATTAAEYLRDINGYKQNI
HHHHHHHCCCCCHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure
MKGTNSMFDIIIIGSGPAGLSAAIYAKRANLNVAIAEKEYEGTGQIAESGNVNNYLGLPN
CCCCCCEEEEEEEECCCCCCEEEEEEEECCCEEEEEECCCCCCCCEECCCCCCCEECCCC
INGYDLGEKFREHAVSLDVEFIEKEAVQIEAVQNGEKEESAIYRVKFDDDTIAEARALIY
CCCCCHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCCCCCEEEEEEECCCHHHHHEEEEE
TAGAYPRKAGVPGEDEYTGKGVSYCAICDGAFYKGKTAAVLGGGDTALDDALYLSDICEK
ECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
VYLVHRRDSFRGAQSTVELLKQKENVELVLNETVTEIYGEKKPTGIKLKSGRTLAVDGVF
HHEEECCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCEEEECCCEEEECEEE
VAYGSVPQSELIKNLVQLDERGYVVAGEDGITYAATKNGDHDRSVQPGLYVAGDVRTKTL
EEECCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEEECCCHHHHH
RQVVTAVSDGANAATTAAEYLRDINGYKQNI
HHHHHHHCCCCCHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]