Click here to switch to the map view.

The map label for this gene is malL [H]

Identifier: 238923280

GI number: 238923280

Start: 795844

End: 797529

Strand: Direct

Name: malL [H]

Synonym: EUBREC_0891

Alternate gene names: 238923280

Gene position: 795844-797529 (Clockwise)

Preceding gene: 238923278

Following gene: 238923281

Centisome position: 23.07

GC content: 43.18

Gene sequence:

>1686_bases
ATGGAGAGAAAATGGTGGCATGACAAGGTGGCATATCAGATTTATCCAAAGAGCTTTCTGGATACAAACGGTGACGGAAT
AGGAGATTTAAGAGGTATCATTTCAAAGCTGGATTATTTAAAATCGCTTGGAATTGACATCATATGGCTGTCTCCGATAT
ATAAATCGCCATTTGTGGATCAGGGCTATGACATATCTGATTACTATGCGATAGCTGAAGAGTTCGGTACTATGGAGGAG
TTTGATGAGCTCCTTGCCGAGGCAAAGAAGCGTGATATGCACATCATCATGGATCTGGTAATAAATCACTGCTCGGATAA
GCACGAATGGTTTCAAAAGGCACTTAAGGATCCGGATGGAGAGTATGCTGATTACTTTTATTTCAGAAAAGGTAAAAACG
GCAATCCGCCGAGCAATTACCGCTCTTATTTTGGCGGAAGCTGCTGGGAGAAGGTGCCGGGCACGGACAAGTATTATCTG
CACATGTTTGCGAAGGAGCAGCCGGATTTAAACTGGGAGAATGAAAAGCTAAGACAAAAGCTTTATGAGATGATTAACTG
GTGGCTTGATAAGGGCTTGTCAGGATTTAGAATAGATGCGATAATCAATATAAAGAAAAATCTTGATTTCCCTGATTTTG
AGCCGGATGCAGAGGACGGACTGGCTGCCTGCTACAAGATGGTTGAAAGTGCAGAAGGTGTCGGAGAGCTCTTAGAGGAA
TTAAAGAACAATACATTTAAGAAGTATGATGCATTTACGGTTGGCGAGGTATTCAATATGAAGCCTGAGGAACTGCCGGA
GTTTATCGGTGAGAATGGGCATTTTTCAACAATATTTGATTTTTGTGCACAGTGCTTAAGTGATGGAGAGCATGGCTGGT
ATGATGCACCGGAAATAGATTTTGACACATGGAGAAAGGCCATTCTTGGTTCACAGCTTGAGACAGAAAAGTACGGCTTT
AAGGCCAATATCATAGAAAATCATGATGAGCCGAGAGGTGCCTCAAGATTTTTACCAAAGCATGCTCAAAATCCTGCCGG
AATAAAGATGTTAGGAACTGTCAGCGTACTGCTTCGAGGCATTCCGTTTATATACCAGGGACAGGAAATCGGTATGCAAA
ATGCAAAATGGAACAGTATAGATGAGTATGACGATATCAGCACAAAGGATCAGTACAAGGCAGCACTTGCAGCAGGCTTA
TCAAAGGAGCAGGCACTTGCGGCCTGTGGAAGGATGAGCAGGGATAATGCAAGGACACCTATGCAGTGGAGTGATGAGGC
AAATGCCGGTTTTACCACAGCAAAGCCATGGCTTAAGGTCAATGAAAACTATAAGGCTATCAATGTTGCGGCGCAGGAAA
AGGATCCTTCATCTGTTTTGAACTATTACAGAAGGCTTGTGGCACTCAGAAAGTCAGATGAATATAAGGAGCTGTTCACC
TACGGCAGATGTGTTCCGGCATATGAGGATACAGATGGTATCATGGCTTATTACAGAGAGGATGAAAATAAGCGAGTGCT
GGTTGTGGCAAATTTTGGTAGTAAAGAGGCACAAATCAGGCTGGATGGCAGTGTGAAAAAGGTGCTTTTGTCCAACACAA
ATGATGCTGAAAAGAGCACTGTTTCAGTTGGAGCATCCGAGCTTAAGCTTGAAAGCTGTGAGGTTTTGGTGGTGCTTGTA
AAATAG

Upstream 100 bases:

>100_bases
TATACTAAGCCCTTTTTATAATAGCAGTATAATACATCAAGGCGAAGTGCTCAAGATGTAAATGAGTGCAAAATTTATGA
TTAGATAAGAGGTACACATT

Downstream 100 bases:

>100_bases
CATAATTTGATACAGCATTAAAGAAACCAGGCTGAATTTTTACAAAAAGAAACAGCTATAAGAGATAACAAAAAGAGATA
ATGAAGAGACAATGAAGAGA

Product: oligo-1,6-glucosidase

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MERKWWHDKVAYQIYPKSFLDTNGDGIGDLRGIISKLDYLKSLGIDIIWLSPIYKSPFVDQGYDISDYYAIAEEFGTMEE
FDELLAEAKKRDMHIIMDLVINHCSDKHEWFQKALKDPDGEYADYFYFRKGKNGNPPSNYRSYFGGSCWEKVPGTDKYYL
HMFAKEQPDLNWENEKLRQKLYEMINWWLDKGLSGFRIDAIINIKKNLDFPDFEPDAEDGLAACYKMVESAEGVGELLEE
LKNNTFKKYDAFTVGEVFNMKPEELPEFIGENGHFSTIFDFCAQCLSDGEHGWYDAPEIDFDTWRKAILGSQLETEKYGF
KANIIENHDEPRGASRFLPKHAQNPAGIKMLGTVSVLLRGIPFIYQGQEIGMQNAKWNSIDEYDDISTKDQYKAALAAGL
SKEQALAACGRMSRDNARTPMQWSDEANAGFTTAKPWLKVNENYKAINVAAQEKDPSSVLNYYRRLVALRKSDEYKELFT
YGRCVPAYEDTDGIMAYYREDENKRVLVVANFGSKEAQIRLDGSVKKVLLSNTNDAEKSTVSVGASELKLESCEVLVVLV
K

Sequences:

>Translated_561_residues
MERKWWHDKVAYQIYPKSFLDTNGDGIGDLRGIISKLDYLKSLGIDIIWLSPIYKSPFVDQGYDISDYYAIAEEFGTMEE
FDELLAEAKKRDMHIIMDLVINHCSDKHEWFQKALKDPDGEYADYFYFRKGKNGNPPSNYRSYFGGSCWEKVPGTDKYYL
HMFAKEQPDLNWENEKLRQKLYEMINWWLDKGLSGFRIDAIINIKKNLDFPDFEPDAEDGLAACYKMVESAEGVGELLEE
LKNNTFKKYDAFTVGEVFNMKPEELPEFIGENGHFSTIFDFCAQCLSDGEHGWYDAPEIDFDTWRKAILGSQLETEKYGF
KANIIENHDEPRGASRFLPKHAQNPAGIKMLGTVSVLLRGIPFIYQGQEIGMQNAKWNSIDEYDDISTKDQYKAALAAGL
SKEQALAACGRMSRDNARTPMQWSDEANAGFTTAKPWLKVNENYKAINVAAQEKDPSSVLNYYRRLVALRKSDEYKELFT
YGRCVPAYEDTDGIMAYYREDENKRVLVVANFGSKEAQIRLDGSVKKVLLSNTNDAEKSTVSVGASELKLESCEVLVVLV
K
>Mature_561_residues
MERKWWHDKVAYQIYPKSFLDTNGDGIGDLRGIISKLDYLKSLGIDIIWLSPIYKSPFVDQGYDISDYYAIAEEFGTMEE
FDELLAEAKKRDMHIIMDLVINHCSDKHEWFQKALKDPDGEYADYFYFRKGKNGNPPSNYRSYFGGSCWEKVPGTDKYYL
HMFAKEQPDLNWENEKLRQKLYEMINWWLDKGLSGFRIDAIINIKKNLDFPDFEPDAEDGLAACYKMVESAEGVGELLEE
LKNNTFKKYDAFTVGEVFNMKPEELPEFIGENGHFSTIFDFCAQCLSDGEHGWYDAPEIDFDTWRKAILGSQLETEKYGF
KANIIENHDEPRGASRFLPKHAQNPAGIKMLGTVSVLLRGIPFIYQGQEIGMQNAKWNSIDEYDDISTKDQYKAALAAGL
SKEQALAACGRMSRDNARTPMQWSDEANAGFTTAKPWLKVNENYKAINVAAQEKDPSSVLNYYRRLVALRKSDEYKELFT
YGRCVPAYEDTDGIMAYYREDENKRVLVVANFGSKEAQIRLDGSVKKVLLSNTNDAEKSTVSVGASELKLESCEVLVVLV
K

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=201, Percent_Identity=40.7960199004975, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI61744475, Length=136, Percent_Identity=33.0882352941176, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI65506891, Length=136, Percent_Identity=33.0882352941176, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI61744479, Length=136, Percent_Identity=33.0882352941176, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI61744477, Length=136, Percent_Identity=33.0882352941176, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI61744481, Length=136, Percent_Identity=33.0882352941176, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI61744483, Length=136, Percent_Identity=33.0882352941176, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1790687, Length=545, Percent_Identity=37.2477064220184, Blast_Score=362, Evalue=1e-101,
Organism=Escherichia coli, GI1786604, Length=357, Percent_Identity=24.3697478991597, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI32565753, Length=572, Percent_Identity=24.3006993006993, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25147709, Length=204, Percent_Identity=29.4117647058824, Blast_Score=92, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319776, Length=568, Percent_Identity=36.443661971831, Blast_Score=311, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6321731, Length=568, Percent_Identity=36.2676056338028, Blast_Score=310, Evalue=3e-85,
Organism=Saccharomyces cerevisiae, GI6322245, Length=539, Percent_Identity=35.8070500927644, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6321726, Length=550, Percent_Identity=34.7272727272727, Blast_Score=303, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6322241, Length=581, Percent_Identity=34.4234079173838, Blast_Score=296, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6322021, Length=581, Percent_Identity=34.4234079173838, Blast_Score=296, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6324416, Length=579, Percent_Identity=34.3696027633851, Blast_Score=294, Evalue=2e-80,
Organism=Drosophila melanogaster, GI221330053, Length=592, Percent_Identity=35.8108108108108, Blast_Score=290, Evalue=3e-78,
Organism=Drosophila melanogaster, GI24583749, Length=540, Percent_Identity=35.7407407407407, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24583747, Length=540, Percent_Identity=35.7407407407407, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI24583745, Length=583, Percent_Identity=33.4476843910806, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24586599, Length=594, Percent_Identity=31.6498316498317, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI45549022, Length=564, Percent_Identity=33.5106382978723, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24586597, Length=511, Percent_Identity=34.2465753424658, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24586589, Length=506, Percent_Identity=35.9683794466403, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24586591, Length=498, Percent_Identity=34.7389558232932, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586587, Length=497, Percent_Identity=33.4004024144869, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24586593, Length=206, Percent_Identity=50.4854368932039, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI281360393, Length=152, Percent_Identity=46.0526315789474, Blast_Score=142, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 64209; Mature: 64209

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKWWHDKVAYQIYPKSFLDTNGDGIGDLRGIISKLDYLKSLGIDIIWLSPIYKSPFVD
CCCCCCCCCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHCCCCCC
QGYDISDYYAIAEEFGTMEEFDELLAEAKKRDMHIIMDLVINHCSDKHEWFQKALKDPDG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
EYADYFYFRKGKNGNPPSNYRSYFGGSCWEKVPGTDKYYLHMFAKEQPDLNWENEKLRQK
CCCCEEEEECCCCCCCCHHHHHHCCCCHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHH
LYEMINWWLDKGLSGFRIDAIINIKKNLDFPDFEPDAEDGLAACYKMVESAEGVGELLEE
HHHHHHHHHHCCCCCEEEEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
LKNNTFKKYDAFTVGEVFNMKPEELPEFIGENGHFSTIFDFCAQCLSDGEHGWYDAPEID
HHCCCCHHHCCEEHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
FDTWRKAILGSQLETEKYGFKANIIENHDEPRGASRFLPKHAQNPAGIKMLGTVSVLLRG
HHHHHHHHHCCCCCHHHCCCEEEEECCCCCCCCHHHCCCHHCCCCCCEEHHHHHHHHHHC
IPFIYQGQEIGMQNAKWNSIDEYDDISTKDQYKAALAAGLSKEQALAACGRMSRDNARTP
CCCEECCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
MQWSDEANAGFTTAKPWLKVNENYKAINVAAQEKDPSSVLNYYRRLVALRKSDEYKELFT
CCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHH
YGRCVPAYEDTDGIMAYYREDENKRVLVVANFGSKEAQIRLDGSVKKVLLSNTNDAEKST
HCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEEEECCCCHHHHCCCCCCCHHHH
VSVGASELKLESCEVLVVLVK
HHCCHHHHEECCCEEEEEEEC
>Mature Secondary Structure
MERKWWHDKVAYQIYPKSFLDTNGDGIGDLRGIISKLDYLKSLGIDIIWLSPIYKSPFVD
CCCCCCCCCCEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCHHCCCCCC
QGYDISDYYAIAEEFGTMEEFDELLAEAKKRDMHIIMDLVINHCSDKHEWFQKALKDPDG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
EYADYFYFRKGKNGNPPSNYRSYFGGSCWEKVPGTDKYYLHMFAKEQPDLNWENEKLRQK
CCCCEEEEECCCCCCCCHHHHHHCCCCHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHHH
LYEMINWWLDKGLSGFRIDAIINIKKNLDFPDFEPDAEDGLAACYKMVESAEGVGELLEE
HHHHHHHHHHCCCCCEEEEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
LKNNTFKKYDAFTVGEVFNMKPEELPEFIGENGHFSTIFDFCAQCLSDGEHGWYDAPEID
HHCCCCHHHCCEEHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
FDTWRKAILGSQLETEKYGFKANIIENHDEPRGASRFLPKHAQNPAGIKMLGTVSVLLRG
HHHHHHHHHCCCCCHHHCCCEEEEECCCCCCCCHHHCCCHHCCCCCCEEHHHHHHHHHHC
IPFIYQGQEIGMQNAKWNSIDEYDDISTKDQYKAALAAGLSKEQALAACGRMSRDNARTP
CCCEECCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCC
MQWSDEANAGFTTAKPWLKVNENYKAINVAAQEKDPSSVLNYYRRLVALRKSDEYKELFT
CCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHH
YGRCVPAYEDTDGIMAYYREDENKRVLVVANFGSKEAQIRLDGSVKKVLLSNTNDAEKST
HCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEEEECCCCHHHHCCCCCCCHHHH
VSVGASELKLESCEVLVVLVK
HHCCHHHHEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2120057; 8370659; 9193006 [H]