Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 238923244

GI number: 238923244

Start: 760632

End: 761669

Strand: Direct

Name: gcp [H]

Synonym: EUBREC_0841

Alternate gene names: 238923244

Gene position: 760632-761669 (Clockwise)

Preceding gene: 238923243

Following gene: 238923245

Centisome position: 22.05

GC content: 45.66

Gene sequence:

>1038_bases
ATGACAGAAAATACAGAAACAAAAAAAGAAATTAAAATACTTGCAATCGAAAGCTCATGCGACGAGACTGCGGCAGCAGT
TGTAGTAAATGGACGTGATCTGCGAAGTAATGTGATTTCATCGCAGATAGCTCTTCATACTTTATATGGAGGGGTAGTAC
CGGAGATAGCTTCCAGAAAGCATATTGAGAAAATTAATCAGGTTATAGAGCAGGCACTTTCAGATGCACATATGACACTC
GATGATATAGACGCAATAGGCGTAACATATGGTCCGGGGCTCGTAGGAGCACTGCTTGTAGGCGTGGCAGAAGCAAAGGC
TATAGCATACGCAAGAAACATTCCTCTTGTCGGAGTGCACCATATAGAGGGACATATCAGCGCAAATTATATAGAAAATA
AAGACTTAGAGCCGCCATTTCTGGCACTCGTCGTATCAGGAGGACACACGCATCTGGTGAGAGTGGTAGATTACGGTAAA
TATGAGATCCTCGGACGCACGAGGGATGATGCGGCAGGAGAGGCATTTGACAAGGTAGCGAGAGCAATAGGACTTGGCTA
TCCGGGCGGTCCTAAGATAGAAAAGGTTTCACATGAGGGTGACCCGCACAGCATAGAGTTCCCGAGAGCAAAGATTGTGG
GCGGAGTTTATGATTTCAGCTTTAGCGGGCTTAAATCAGCAGTACTCAATTATTTAAACGGCTGCAGGATGAAGGGACTG
GAAATAAACCAGGCAGACGTGGCAGCATCGTTCCAACAGGCGGTTACAGATGTGCTTGTCGGACACGCTGAGAATGCCAT
AGATGAGTTTAAAATGGACAAATTTGCCATTGCGGGAGGCGTTGCTTCTAATGGTATTATCCGTCATGCGATGGAGGAAA
TGTGCGCGCGCAAGGGTGTTAAATTCTATCGTCCGTCACCGATACTGTGTACAGACAATGCTGCTATGATAGGTGCGGCA
GCATACTATGATTTTATAGCAGGTAAGAGGTCTGGACTTGATCTGAATGCGGTTCCGAATTTAAAACTTGGTGAATGA

Upstream 100 bases:

>100_bases
ATAAGGAAGGCTGTTGGAGGATTCTTACATTTTATAAGATTGCGGCAGATTCTGATACGGAAACAGAATAGAGTAATATA
ATTAAGAGTGGTGTAATAAA

Downstream 100 bases:

>100_bases
TTCTGTAATTGCTTCCGGTTACACCGGTGTGCAAACATAATGTGCAGATTTATCATGGATAGGAAAATAAAGGAATATGG
ATAAGAAGAAATACACAGCA

Product: metalloendopeptidase, glycoprotease family

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTENTETKKEIKILAIESSCDETAAAVVVNGRDLRSNVISSQIALHTLYGGVVPEIASRKHIEKINQVIEQALSDAHMTL
DDIDAIGVTYGPGLVGALLVGVAEAKAIAYARNIPLVGVHHIEGHISANYIENKDLEPPFLALVVSGGHTHLVRVVDYGK
YEILGRTRDDAAGEAFDKVARAIGLGYPGGPKIEKVSHEGDPHSIEFPRAKIVGGVYDFSFSGLKSAVLNYLNGCRMKGL
EINQADVAASFQQAVTDVLVGHAENAIDEFKMDKFAIAGGVASNGIIRHAMEEMCARKGVKFYRPSPILCTDNAAMIGAA
AYYDFIAGKRSGLDLNAVPNLKLGE

Sequences:

>Translated_345_residues
MTENTETKKEIKILAIESSCDETAAAVVVNGRDLRSNVISSQIALHTLYGGVVPEIASRKHIEKINQVIEQALSDAHMTL
DDIDAIGVTYGPGLVGALLVGVAEAKAIAYARNIPLVGVHHIEGHISANYIENKDLEPPFLALVVSGGHTHLVRVVDYGK
YEILGRTRDDAAGEAFDKVARAIGLGYPGGPKIEKVSHEGDPHSIEFPRAKIVGGVYDFSFSGLKSAVLNYLNGCRMKGL
EINQADVAASFQQAVTDVLVGHAENAIDEFKMDKFAIAGGVASNGIIRHAMEEMCARKGVKFYRPSPILCTDNAAMIGAA
AYYDFIAGKRSGLDLNAVPNLKLGE
>Mature_344_residues
TENTETKKEIKILAIESSCDETAAAVVVNGRDLRSNVISSQIALHTLYGGVVPEIASRKHIEKINQVIEQALSDAHMTLD
DIDAIGVTYGPGLVGALLVGVAEAKAIAYARNIPLVGVHHIEGHISANYIENKDLEPPFLALVVSGGHTHLVRVVDYGKY
EILGRTRDDAAGEAFDKVARAIGLGYPGGPKIEKVSHEGDPHSIEFPRAKIVGGVYDFSFSGLKSAVLNYLNGCRMKGLE
INQADVAASFQQAVTDVLVGHAENAIDEFKMDKFAIAGGVASNGIIRHAMEEMCARKGVKFYRPSPILCTDNAAMIGAAA
YYDFIAGKRSGLDLNAVPNLKLGE

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=342, Percent_Identity=32.7485380116959, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI8923380, Length=329, Percent_Identity=31.9148936170213, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1789445, Length=337, Percent_Identity=42.7299703264095, Blast_Score=278, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17557464, Length=322, Percent_Identity=32.2981366459627, Blast_Score=140, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71995670, Length=332, Percent_Identity=27.710843373494, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320099, Length=345, Percent_Identity=31.0144927536232, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6322891, Length=301, Percent_Identity=29.5681063122924, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI20129063, Length=333, Percent_Identity=33.6336336336336, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI21357207, Length=330, Percent_Identity=31.2121212121212, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36895; Mature: 36763

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTENTETKKEIKILAIESSCDETAAAVVVNGRDLRSNVISSQIALHTLYGGVVPEIASRK
CCCCCCCCCEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HIEKINQVIEQALSDAHMTLDDIDAIGVTYGPGLVGALLVGVAEAKAIAYARNIPLVGVH
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HIEGHISANYIENKDLEPPFLALVVSGGHTHLVRVVDYGKYEILGRTRDDAAGEAFDKVA
EECCCEEECEECCCCCCCCEEEEEEECCCEEEEEEEECCCEEEECCCCCCHHHHHHHHHH
RAIGLGYPGGPKIEKVSHEGDPHSIEFPRAKIVGGVYDFSFSGLKSAVLNYLNGCRMKGL
HHHCCCCCCCCCCEECCCCCCCCCEECCHHHHHCCHHHCCHHHHHHHHHHHHHCCEECCC
EINQADVAASFQQAVTDVLVGHAENAIDEFKMDKFAIAGGVASNGIIRHAMEEMCARKGV
CCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCC
KFYRPSPILCTDNAAMIGAAAYYDFIAGKRSGLDLNAVPNLKLGE
EEECCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TENTETKKEIKILAIESSCDETAAAVVVNGRDLRSNVISSQIALHTLYGGVVPEIASRK
CCCCCCCCEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HIEKINQVIEQALSDAHMTLDDIDAIGVTYGPGLVGALLVGVAEAKAIAYARNIPLVGVH
HHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
HIEGHISANYIENKDLEPPFLALVVSGGHTHLVRVVDYGKYEILGRTRDDAAGEAFDKVA
EECCCEEECEECCCCCCCCEEEEEEECCCEEEEEEEECCCEEEECCCCCCHHHHHHHHHH
RAIGLGYPGGPKIEKVSHEGDPHSIEFPRAKIVGGVYDFSFSGLKSAVLNYLNGCRMKGL
HHHCCCCCCCCCCEECCCCCCCCCEECCHHHHHCCHHHCCHHHHHHHHHHHHHCCEECCC
EINQADVAASFQQAVTDVLVGHAENAIDEFKMDKFAIAGGVASNGIIRHAMEEMCARKGV
CCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHCCC
KFYRPSPILCTDNAAMIGAAAYYDFIAGKRSGLDLNAVPNLKLGE
EEECCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA