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The map label for this gene is mcp4 [H]

Identifier: 238922573

GI number: 238922573

Start: 141869

End: 143557

Strand: Direct

Name: mcp4 [H]

Synonym: EUBREC_0147

Alternate gene names: 238922573

Gene position: 141869-143557 (Clockwise)

Preceding gene: 238922572

Following gene: 238922574

Centisome position: 4.11

GC content: 40.79

Gene sequence:

>1689_bases
ATGGAACAGAGTAAAACTAAAAAAAGAGGTACATTTGCAGCCAAAATCATAGTAATGGTGATTTTAGCTGTTATAGTTTC
AAATGTAATTTGTATGGTATTTATTCTTGAAAGCTCCAAAAAACAAATTACAGACAGTGTCAAGCATACCATGGTAGATG
TTGTTAATACAACGTCAAAAATCATGGAAAATGAGATTAGTAATTCAGGTGTTGATGATCTGGATTATGATGGTTATGCC
AATAATCTTTCAGATGTAAAGCTTGAAGGCATGGACAGTGCATACATGTATGTGGTTCAAAATGATGGCACAATGCTTTA
TCATCCTACAAAGGAAAAGGTTGGACAGCCTGTTGAGAATGCTGTAATTAAAGGCGTTGTACAACAGCTTCAGGATGGCA
AAAAACCGGGCACGACTGTTGTAGAATATGATTTCAATGGAACAACAAAGTATTCGGCATATACGATTTTGAACAATGAA
AATATACTTGTGCTTACAGCAGATGAATCTGAGGCACTTGCAGGAATCACTACTGTAACAGGAGTTGCCGTTGGAATCAT
TGCTATTGTTGTGCTTATTGCAATTACTATCTCATTCATAATGGGACGCAGGCTCATGAGACCGCTTGTAAAGGTCAGTA
CAATAATTGAGGATGTTGCCAATGGTAATATTGAGGCAGATTTCAGTGTGGTCAAGGAGTCAAATGATGAGATAGGCCTG
ATTATAGAAAAGATGAAGGAGCTCACACAATCGCTTGGAAGTATAGTCGGAAAGATAAGAAATTCCAGTGATACGATGTC
ATCAAACAGCTATGAGCTCAATGACACAAGCAGTCAGACACTTGCTGCAAATAACGAGATATCCAAGGCCGTCGAGGATG
TTGCAGAGGGCTCTACAGGCATGGCAGCATCTATTTCCAAGATTAATGAAAATCTTCTGGAGATGAGCAATGAAACAAAG
GACATTAATGCCTCTGTTGATGAAATCAAAAACCAGACGGTAGCAGTGCAGGATAGCAGTAAAATCATGAATGACAAGAT
TAAATCCATGCAGGATAGCAGCCACAAGATGGATGAGGGTATCTCAGCAATTTCAAAACGCATAGAAACTGTAAATACTA
CGGTTGACAAGGTGAGCAATATTGTCTCTGTCATTGAGGAAATATCCAGTGAAACCAATCTTTTGTCACTCAATGCATCT
ATAGAAGCAGCCAGAGCCGGCGATGCAGGAAAAGGCTTCGCAGTGGTGGCACAGGAGATTCGAGTGCTTTCAGACAATAC
CAATACGGAGCTTGAGAATATCAAGCAGATAATATCATCACTGGTTGAAGAGTGCAGGTATTGTGTTCAGGCATCCGGCA
CCATCGTCGAGGATAATGCCAAGCAGAAGGAAGAGATTAAGGCAGTACTCGATGAATTTGGCTCACTTGATGAGCAGATT
CAAAAGACAGCAGAAAAAGCTGATGAAATCGAAGAGCTTGTCACTGCGATGATTGAGCTGAACGATGACATCACGAAGAG
CAGCAACAGCCTGACAGACGTCAGCGCAGCAAATGCCGCAGCAACCGAAGAGATGAATGCCAACATCGAGGAGCTCAATG
CGATGATGCACGGAGTTTCAGAAATGGCAGGACACATGAATGATGAGTCTGATGGATTGAAGGAAGCATTATCGTTCTTT
AATAATTAA

Upstream 100 bases:

>100_bases
ACTGATAAACTATTGTATAATTTCACCAAAAATGGTAATATTGTCTTATAATTTTAAGCTAAAGGAGTAGCAGTAGCAAT
AGGATTGGAGAGATGGTCAT

Downstream 100 bases:

>100_bases
TTGTAAGTATTCATAAATGAACATTGACCTCCTTTGCGCTTTAAGTTTATCATTAAAGCAAAAAGGAGGTTTTTGTCAGT
TTTCAATGTAAATCAGTCGT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MEQSKTKKRGTFAAKIIVMVILAVIVSNVICMVFILESSKKQITDSVKHTMVDVVNTTSKIMENEISNSGVDDLDYDGYA
NNLSDVKLEGMDSAYMYVVQNDGTMLYHPTKEKVGQPVENAVIKGVVQQLQDGKKPGTTVVEYDFNGTTKYSAYTILNNE
NILVLTADESEALAGITTVTGVAVGIIAIVVLIAITISFIMGRRLMRPLVKVSTIIEDVANGNIEADFSVVKESNDEIGL
IIEKMKELTQSLGSIVGKIRNSSDTMSSNSYELNDTSSQTLAANNEISKAVEDVAEGSTGMAASISKINENLLEMSNETK
DINASVDEIKNQTVAVQDSSKIMNDKIKSMQDSSHKMDEGISAISKRIETVNTTVDKVSNIVSVIEEISSETNLLSLNAS
IEAARAGDAGKGFAVVAQEIRVLSDNTNTELENIKQIISSLVEECRYCVQASGTIVEDNAKQKEEIKAVLDEFGSLDEQI
QKTAEKADEIEELVTAMIELNDDITKSSNSLTDVSAANAAATEEMNANIEELNAMMHGVSEMAGHMNDESDGLKEALSFF
NN

Sequences:

>Translated_562_residues
MEQSKTKKRGTFAAKIIVMVILAVIVSNVICMVFILESSKKQITDSVKHTMVDVVNTTSKIMENEISNSGVDDLDYDGYA
NNLSDVKLEGMDSAYMYVVQNDGTMLYHPTKEKVGQPVENAVIKGVVQQLQDGKKPGTTVVEYDFNGTTKYSAYTILNNE
NILVLTADESEALAGITTVTGVAVGIIAIVVLIAITISFIMGRRLMRPLVKVSTIIEDVANGNIEADFSVVKESNDEIGL
IIEKMKELTQSLGSIVGKIRNSSDTMSSNSYELNDTSSQTLAANNEISKAVEDVAEGSTGMAASISKINENLLEMSNETK
DINASVDEIKNQTVAVQDSSKIMNDKIKSMQDSSHKMDEGISAISKRIETVNTTVDKVSNIVSVIEEISSETNLLSLNAS
IEAARAGDAGKGFAVVAQEIRVLSDNTNTELENIKQIISSLVEECRYCVQASGTIVEDNAKQKEEIKAVLDEFGSLDEQI
QKTAEKADEIEELVTAMIELNDDITKSSNSLTDVSAANAAATEEMNANIEELNAMMHGVSEMAGHMNDESDGLKEALSFF
NN
>Mature_562_residues
MEQSKTKKRGTFAAKIIVMVILAVIVSNVICMVFILESSKKQITDSVKHTMVDVVNTTSKIMENEISNSGVDDLDYDGYA
NNLSDVKLEGMDSAYMYVVQNDGTMLYHPTKEKVGQPVENAVIKGVVQQLQDGKKPGTTVVEYDFNGTTKYSAYTILNNE
NILVLTADESEALAGITTVTGVAVGIIAIVVLIAITISFIMGRRLMRPLVKVSTIIEDVANGNIEADFSVVKESNDEIGL
IIEKMKELTQSLGSIVGKIRNSSDTMSSNSYELNDTSSQTLAANNEISKAVEDVAEGSTGMAASISKINENLLEMSNETK
DINASVDEIKNQTVAVQDSSKIMNDKIKSMQDSSHKMDEGISAISKRIETVNTTVDKVSNIVSVIEEISSETNLLSLNAS
IEAARAGDAGKGFAVVAQEIRVLSDNTNTELENIKQIISSLVEECRYCVQASGTIVEDNAKQKEEIKAVLDEFGSLDEQI
QKTAEKADEIEELVTAMIELNDDITKSSNSLTDVSAANAAATEEMNANIEELNAMMHGVSEMAGHMNDESDGLKEALSFF
NN

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=424, Percent_Identity=28.3018867924528, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI2367378, Length=297, Percent_Identity=26.2626262626263, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788194, Length=353, Percent_Identity=26.628895184136, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1789453, Length=362, Percent_Identity=29.0055248618785, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788195, Length=312, Percent_Identity=24.6794871794872, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60834; Mature: 60834

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSKTKKRGTFAAKIIVMVILAVIVSNVICMVFILESSKKQITDSVKHTMVDVVNTTSK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
IMENEISNSGVDDLDYDGYANNLSDVKLEGMDSAYMYVVQNDGTMLYHPTKEKVGQPVEN
HHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEECCCHHHHCCCHHH
AVIKGVVQQLQDGKKPGTTVVEYDFNGTTKYSAYTILNNENILVLTADESEALAGITTVT
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHH
GVAVGIIAIVVLIAITISFIMGRRLMRPLVKVSTIIEDVANGNIEADFSVVKESNDEIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHH
IIEKMKELTQSLGSIVGKIRNSSDTMSSNSYELNDTSSQTLAANNEISKAVEDVAEGSTG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHCCHHHHHHHHHHHCCCCC
MAASISKINENLLEMSNETKDINASVDEIKNQTVAVQDSSKIMNDKIKSMQDSSHKMDEG
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
ISAISKRIETVNTTVDKVSNIVSVIEEISSETNLLSLNASIEAARAGDAGKGFAVVAQEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCCCHHHHHHHH
RVLSDNTNTELENIKQIISSLVEECRYCVQASGTIVEDNAKQKEEIKAVLDEFGSLDEQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCHHHHH
QKTAEKADEIEELVTAMIELNDDITKSSNSLTDVSAANAAATEEMNANIEELNAMMHGVS
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EMAGHMNDESDGLKEALSFFNN
HHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MEQSKTKKRGTFAAKIIVMVILAVIVSNVICMVFILESSKKQITDSVKHTMVDVVNTTSK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
IMENEISNSGVDDLDYDGYANNLSDVKLEGMDSAYMYVVQNDGTMLYHPTKEKVGQPVEN
HHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCEEEECCCHHHHCCCHHH
AVIKGVVQQLQDGKKPGTTVVEYDFNGTTKYSAYTILNNENILVLTADESEALAGITTVT
HHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHH
GVAVGIIAIVVLIAITISFIMGRRLMRPLVKVSTIIEDVANGNIEADFSVVKESNDEIGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHH
IIEKMKELTQSLGSIVGKIRNSSDTMSSNSYELNDTSSQTLAANNEISKAVEDVAEGSTG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHCCHHHHHHHHHHHCCCCC
MAASISKINENLLEMSNETKDINASVDEIKNQTVAVQDSSKIMNDKIKSMQDSSHKMDEG
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHH
ISAISKRIETVNTTVDKVSNIVSVIEEISSETNLLSLNASIEAARAGDAGKGFAVVAQEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHCCCCCCCCHHHHHHHH
RVLSDNTNTELENIKQIISSLVEECRYCVQASGTIVEDNAKQKEEIKAVLDEFGSLDEQI
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCHHHHH
QKTAEKADEIEELVTAMIELNDDITKSSNSLTDVSAANAAATEEMNANIEELNAMMHGVS
HHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
EMAGHMNDESDGLKEALSFFNN
HHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]