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The map label for this gene is 238922541

Identifier: 238922541

GI number: 238922541

Start: 112806

End: 113291

Strand: Direct

Name: 238922541

Synonym: EUBREC_0115

Alternate gene names: NA

Gene position: 112806-113291 (Clockwise)

Preceding gene: 238922540

Following gene: 238922542

Centisome position: 3.27

GC content: 51.03

Gene sequence:

>486_bases
ATGGGAGCTTCGGAAAAGAGAAAGGATTATATCTCATGGGATGAGTATTTTATGGGCATAGCGATGCTTTCAGGCATGCG
CTCGAAGGATCCGAATACCCAGGTGGGGGCGTGCATAGTGGACCCGGAGCACAAGATACTCTCCATGGGCTATAACGGCT
TTCCTCTTGGCTGCTCAGATGATGAGTTCACCTGGGCCAGAGAGGGAGAGGATAACAAGTATTTCTATTCTACACACAGC
GAGCTCAATGCCATCTTAAACTACAGGGGCGGAAGCCTTGAGGGAGCGACCATATATGTCACATTGTTTCCGTGCAATGA
GTGCGCTAAGGCAATCATACAGTCCGGCATCAGGGAAGTAGTCTACGACTGTGACAAATACGAGGGCACGGCCAGCGTGA
CAGCTTCAAAGAGGATGCTTAGGGCAGCGGGGGTTACAATTCGCAGGTATGAGCACACTGACCGTGAGGTGACGCTTGTG
CTGTAA

Upstream 100 bases:

>100_bases
ATGATGATAATAGCTGCAGGTTGCCCTGAGGTGTAAACAGTGATATAAAACTGTAAAGTAACAGACAGTGTGATAGACCA
TATTGAATGGAGGTGTATAT

Downstream 100 bases:

>100_bases
TCGCCGAAAAAGTGATAATACTGCAATTGTTGTGTCAAATTGACGTGATTTGACATGAAACACATTTATTTTTTATGCAT
TTTACACATAAAAATGTAGA

Product: dCMP deaminase

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MGASEKRKDYISWDEYFMGIAMLSGMRSKDPNTQVGACIVDPEHKILSMGYNGFPLGCSDDEFTWAREGEDNKYFYSTHS
ELNAILNYRGGSLEGATIYVTLFPCNECAKAIIQSGIREVVYDCDKYEGTASVTASKRMLRAAGVTIRRYEHTDREVTLV
L

Sequences:

>Translated_161_residues
MGASEKRKDYISWDEYFMGIAMLSGMRSKDPNTQVGACIVDPEHKILSMGYNGFPLGCSDDEFTWAREGEDNKYFYSTHS
ELNAILNYRGGSLEGATIYVTLFPCNECAKAIIQSGIREVVYDCDKYEGTASVTASKRMLRAAGVTIRRYEHTDREVTLV
L
>Mature_160_residues
GASEKRKDYISWDEYFMGIAMLSGMRSKDPNTQVGACIVDPEHKILSMGYNGFPLGCSDDEFTWAREGEDNKYFYSTHSE
LNAILNYRGGSLEGATIYVTLFPCNECAKAIIQSGIREVVYDCDKYEGTASVTASKRMLRAAGVTIRRYEHTDREVTLVL

Specific function: Unknown

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=151, Percent_Identity=53.6423841059603, Blast_Score=180, Evalue=5e-46,
Organism=Homo sapiens, GI61742821, Length=151, Percent_Identity=53.6423841059603, Blast_Score=179, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17557019, Length=130, Percent_Identity=50, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6321938, Length=150, Percent_Identity=32.6666666666667, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24667298, Length=164, Percent_Identity=51.219512195122, Blast_Score=179, Evalue=9e-46,
Organism=Drosophila melanogaster, GI24667302, Length=164, Percent_Identity=51.219512195122, Blast_Score=179, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 18082; Mature: 17950

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASEKRKDYISWDEYFMGIAMLSGMRSKDPNTQVGACIVDPEHKILSMGYNGFPLGCSD
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCC
DEFTWAREGEDNKYFYSTHSELNAILNYRGGSLEGATIYVTLFPCNECAKAIIQSGIREV
CCCEEECCCCCCEEEEECHHHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHH
VYDCDKYEGTASVTASKRMLRAAGVTIRRYEHTDREVTLVL
HHHCCCCCCCEEHHHHHHHHHHHCCEEEEEECCCCEEEEEC
>Mature Secondary Structure 
GASEKRKDYISWDEYFMGIAMLSGMRSKDPNTQVGACIVDPEHKILSMGYNGFPLGCSD
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCC
DEFTWAREGEDNKYFYSTHSELNAILNYRGGSLEGATIYVTLFPCNECAKAIIQSGIREV
CCCEEECCCCCCEEEEECHHHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHHHHHHH
VYDCDKYEGTASVTASKRMLRAAGVTIRRYEHTDREVTLVL
HHHCCCCCCCEEHHHHHHHHHHHCCEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8329441 [H]