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The map label for this gene is ykoW [H]

Identifier: 238922195

GI number: 238922195

Start: 392556

End: 393905

Strand: Reverse

Name: ykoW [H]

Synonym: EUBELI_20430

Alternate gene names: 238922195

Gene position: 393905-392556 (Counterclockwise)

Preceding gene: 238922196

Following gene: 238922194

Centisome position: 62.85

GC content: 36.74

Gene sequence:

>1350_bases
ATGATTTTAGCATATTTAAGGCATGTGATATATTTTAAGAAAAGAGGGGGGTATATGGAAAACTGTTATCTTGGGATGGC
AGGGCATAATGTGTTTAATAATAAGGTTAAAGATATTATACATAAGAATGAACATAGTGTTGTTCTACTGGCTCTGGACA
TAAGTAATTTTAAGTACATTAATGATTTTTACGGTATGGATGAGGGTGATAAAGTAATGCAGGACATAGCGGATTATTAT
TTTATTAATGAACCACTGTGCCTAGCTGCTCACGGAATTGGATTTGACCAGTTCAGGGGAGCATATAATGTGGATGGAAT
GACTCAGGAAGATGTTGTTAGTTATATTACAAAAAAGAATGAGAAGTTTGAGGCAGAATTATCAGAACGATACCCACTTG
TATACCAGCATGTTTATGTAGGACTTTATTTTTATGATAACCATGAACTTGATGTGAGAATGGCGGTAGACAGGGCAAAT
CTGGCAAAGAAATCAACTAAAGGAAGATTTGATATCCATTGTTGCATATATTCTGAAGATAACTGTAATGAATACCTTGA
ACATATGGATATGTCTAATGAATTCGTGCATGCATATAATGAGAACAGGATTGAGATATTTTTACAGCCAAAGATTTCTG
TGTCTGAAGGAAAAGCTGTGGGTGCTGAAGCTCTCGTAAGAATGAGAAACAAGGAGGGAGAGCTGATTCCACCTGTAAGG
TTTGTTCCGGTACTTGAACATACAGGAATGATTGAAAAGCTTGATGATATCATGCTGGATAAAACATTTGCATTTCAGCG
TGAATGCATTAATAATGGAATCCGCCCGGTTCCTATATCTGTCAATATATCAAGACAGAGGTTCACAAGCGATGGCTTGC
TTGGTTATGTGATGGAGCTTCAGCAAAAATATGATATAGATGCATCACTTGTTGAACTGGAGATTTTAGAGACAACATTT
ATAGATGCACTGGATGCAATGACAGATGCAATTAATGCATTGAGAAAGCAGGGATTCAGAATAAATGTTGATGATTTTGG
TTCGGGTTATTCGTCACTAAATCAGATTGCTAATATTCCTGCTGATGTTATTAAGTTTGACCGCGTTTTTGCAAGCAGGT
CATTGAAGAATGATAAGGGAAGACAGGTTATTAAGTCGTTAATCCAGATGCTTAAAATGGTAAATTATGAGCTTGTTTTT
GAAGGTGTGGAGACAAAGGAAGAACTTGATACAGTCGTATCTTATGGCTGCGATGTTATTCAGGGCTTTTATTTTGACAA
GCCGCTTCCGGCAAAGGAATTTATACAGAAATACTATAAGGGCAGCAGGGAGTCTACCTATGGGACATAA

Upstream 100 bases:

>100_bases
TTATCAGAAGGATATACATTCCTTCCTATAACATCAACTACGCCTATGTCACACCATGGAATTAACAATTAATATGTGGA
ATTAATGAGATAAATGTGTT

Downstream 100 bases:

>100_bases
TAATATTAACAATGAAGAACTGCTTGAATATATTTTAAAAGATTTTAAAAGCGGCGTTCAGCATGGGATTCTTGTGGCAA
ATCTTACATATATGCTTGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MILAYLRHVIYFKKRGGYMENCYLGMAGHNVFNNKVKDIIHKNEHSVVLLALDISNFKYINDFYGMDEGDKVMQDIADYY
FINEPLCLAAHGIGFDQFRGAYNVDGMTQEDVVSYITKKNEKFEAELSERYPLVYQHVYVGLYFYDNHELDVRMAVDRAN
LAKKSTKGRFDIHCCIYSEDNCNEYLEHMDMSNEFVHAYNENRIEIFLQPKISVSEGKAVGAEALVRMRNKEGELIPPVR
FVPVLEHTGMIEKLDDIMLDKTFAFQRECINNGIRPVPISVNISRQRFTSDGLLGYVMELQQKYDIDASLVELEILETTF
IDALDAMTDAINALRKQGFRINVDDFGSGYSSLNQIANIPADVIKFDRVFASRSLKNDKGRQVIKSLIQMLKMVNYELVF
EGVETKEELDTVVSYGCDVIQGFYFDKPLPAKEFIQKYYKGSRESTYGT

Sequences:

>Translated_449_residues
MILAYLRHVIYFKKRGGYMENCYLGMAGHNVFNNKVKDIIHKNEHSVVLLALDISNFKYINDFYGMDEGDKVMQDIADYY
FINEPLCLAAHGIGFDQFRGAYNVDGMTQEDVVSYITKKNEKFEAELSERYPLVYQHVYVGLYFYDNHELDVRMAVDRAN
LAKKSTKGRFDIHCCIYSEDNCNEYLEHMDMSNEFVHAYNENRIEIFLQPKISVSEGKAVGAEALVRMRNKEGELIPPVR
FVPVLEHTGMIEKLDDIMLDKTFAFQRECINNGIRPVPISVNISRQRFTSDGLLGYVMELQQKYDIDASLVELEILETTF
IDALDAMTDAINALRKQGFRINVDDFGSGYSSLNQIANIPADVIKFDRVFASRSLKNDKGRQVIKSLIQMLKMVNYELVF
EGVETKEELDTVVSYGCDVIQGFYFDKPLPAKEFIQKYYKGSRESTYGT
>Mature_449_residues
MILAYLRHVIYFKKRGGYMENCYLGMAGHNVFNNKVKDIIHKNEHSVVLLALDISNFKYINDFYGMDEGDKVMQDIADYY
FINEPLCLAAHGIGFDQFRGAYNVDGMTQEDVVSYITKKNEKFEAELSERYPLVYQHVYVGLYFYDNHELDVRMAVDRAN
LAKKSTKGRFDIHCCIYSEDNCNEYLEHMDMSNEFVHAYNENRIEIFLQPKISVSEGKAVGAEALVRMRNKEGELIPPVR
FVPVLEHTGMIEKLDDIMLDKTFAFQRECINNGIRPVPISVNISRQRFTSDGLLGYVMELQQKYDIDASLVELEILETTF
IDALDAMTDAINALRKQGFRINVDDFGSGYSSLNQIANIPADVIKFDRVFASRSLKNDKGRQVIKSLIQMLKMVNYELVF
EGVETKEELDTVVSYGCDVIQGFYFDKPLPAKEFIQKYYKGSRESTYGT

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=424, Percent_Identity=27.122641509434, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081921, Length=248, Percent_Identity=30.241935483871, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1790496, Length=252, Percent_Identity=28.1746031746032, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI226510982, Length=322, Percent_Identity=26.3975155279503, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=30.7053941908714, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786507, Length=258, Percent_Identity=24.031007751938, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87081845, Length=234, Percent_Identity=29.4871794871795, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788849, Length=241, Percent_Identity=29.4605809128631, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI87081980, Length=258, Percent_Identity=26.7441860465116, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87082096, Length=243, Percent_Identity=27.5720164609054, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787055, Length=261, Percent_Identity=24.5210727969349, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788502, Length=256, Percent_Identity=24.609375, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 51700; Mature: 51700

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILAYLRHVIYFKKRGGYMENCYLGMAGHNVFNNKVKDIIHKNEHSVVLLALDISNFKYI
CHHHHHHHHHHHHCCCCCHHHEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEH
NDFYGMDEGDKVMQDIADYYFINEPLCLAAHGIGFDQFRGAYNVDGMTQEDVVSYITKKN
HHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHCCC
EKFEAELSERYPLVYQHVYVGLYFYDNHELDVRMAVDRANLAKKSTKGRFDIHCCIYSED
CHHHHHHHHCCCEEEEEEEEEEEEEECCCEEEEEEECHHHHHHHCCCCCEEEEEEEECCC
NCNEYLEHMDMSNEFVHAYNENRIEIFLQPKISVSEGKAVGAEALVRMRNKEGELIPPVR
CHHHHHHHCCCCCHHHHCCCCCEEEEEEECCEECCCCCCCCHHHHHHHHCCCCCCCCCCC
FVPVLEHTGMIEKLDDIMLDKTFAFQRECINNGIRPVPISVNISRQRFTSDGLLGYVMEL
EEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHCCCCCHHHHHHHH
QQKYDIDASLVELEILETTFIDALDAMTDAINALRKQGFRINVDDFGSGYSSLNQIANIP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHCCC
ADVIKFDRVFASRSLKNDKGRQVIKSLIQMLKMVNYELVFEGVETKEELDTVVSYGCDVI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHEEEECCCCHHHHHHHHHHCHHHH
QGFYFDKPLPAKEFIQKYYKGSRESTYGT
HHHCCCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MILAYLRHVIYFKKRGGYMENCYLGMAGHNVFNNKVKDIIHKNEHSVVLLALDISNFKYI
CHHHHHHHHHHHHCCCCCHHHEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCEEH
NDFYGMDEGDKVMQDIADYYFINEPLCLAAHGIGFDQFRGAYNVDGMTQEDVVSYITKKN
HHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHCCC
EKFEAELSERYPLVYQHVYVGLYFYDNHELDVRMAVDRANLAKKSTKGRFDIHCCIYSED
CHHHHHHHHCCCEEEEEEEEEEEEEECCCEEEEEEECHHHHHHHCCCCCEEEEEEEECCC
NCNEYLEHMDMSNEFVHAYNENRIEIFLQPKISVSEGKAVGAEALVRMRNKEGELIPPVR
CHHHHHHHCCCCCHHHHCCCCCEEEEEEECCEECCCCCCCCHHHHHHHHCCCCCCCCCCC
FVPVLEHTGMIEKLDDIMLDKTFAFQRECINNGIRPVPISVNISRQRFTSDGLLGYVMEL
EEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHCCCCCHHHHHHHH
QQKYDIDASLVELEILETTFIDALDAMTDAINALRKQGFRINVDDFGSGYSSLNQIANIP
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHCCC
ADVIKFDRVFASRSLKNDKGRQVIKSLIQMLKMVNYELVFEGVETKEELDTVVSYGCDVI
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHEEEECCCCHHHHHHHHHHCHHHH
QGFYFDKPLPAKEFIQKYYKGSRESTYGT
HHHCCCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]