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The map label for this gene is gmr [H]

Identifier: 238922120

GI number: 238922120

Start: 306331

End: 308106

Strand: Reverse

Name: gmr [H]

Synonym: EUBELI_20355

Alternate gene names: 238922120

Gene position: 308106-306331 (Counterclockwise)

Preceding gene: 238922129

Following gene: 238922113

Centisome position: 49.16

GC content: 31.59

Gene sequence:

>1776_bases
ATGATTATATCAGAAAATCATTTTGGAAAAGAAAATTGTGTTGCTTATTGCGATATCTTAATTAGAAGAAATTATGAAGT
AATTAATGCGGATGAGCATTTTTATCATTTTGTGGAGAAGCTGGTTGGAATTAATTTTCTGGATATTGTGCATCCTGATC
AGCTGAAGGATTTTAAGACAACATTTGAATCATTAAAACCAGGAGAGAATAGCAGAATTATAATTCTGTTAAGAAATGGA
ATTGGTGAATATTATTGGTCAGACATGTACATTTTTAATAATGGCAAGGTGCTTTCAGGTGAGAATATTCTTGAAATAAG
ATGTTTCTTTTTGTCAGCGGTTGAGAGCAGATATCTTATGGGTCTTGATAATATTAATAAATACAGAACACTGCTTTCAG
TGTATCGTAATTATTTGTTCGATTATAACTCGTATACAGATATATTTACTATATATATGTACAGAGGTAATCAGTGTACA
GCACCGGTTAAATGTCCTCTTGAGCAGTTTAAAGACAGAATGCTGTCACTGTTACGAAATGATGCAGAAAAAAAAGAATT
TAATGTTTTTTATAATTATCTTAAAACAGGTTCTAATATGTTTAGCTGCATGGTTTATCTTCCACTTGGTGAGAACAATG
ATGAATTATATAAGTTTAAGGTTAATGGCGACAGTCTTTTTGCCAATAACAAGCATCCCATAGTTGCTGGATATCTTGAA
ACAGCTGATGGAAATGTTAATAATATAATACCGTATTATGCAACAAGTGAAGCAGTTGATTCTGCAACCGGGCTTCTTAA
TAAAAGGGCATGCATGGAATATACAAAAGCAGTGATGGCATCTAATGATAATAAAATTCATTATATGATTATATTTGATG
TAGATAATTTTAAAAGTATCAACGATACATATGGACATCTTTTTGGAGATGAGGTTTTAAGTAAGATTGCTACTATCCTT
AATGCTAATCTTAATGGTCGTGGGATTGCAGGCAGATTTGGCGGGGATGAGTTTTATATTTTTACAAGTAATATTAAAGA
TACTGAAGATTTGAGAATACTTCTTACTACAATGAGAAAAGAACTTCAGTATGCTTTTGACAGCAGAATCGATGAATTTG
GTGTTACTTTATCAGTGGGAGTCAGCGAGTATCCAAAAGATGGAAATAATTATGAAATTCTGTTTAAAAAAGCAGATAAA
TGTCTATATCTGGCTAAAGAAAAAGGAAGAAACCGTTTTATTATCTATAATGAAGAAATACATGGTTCTATTCAGGATAA
TGGCAGACACATACATAAAATACTTGATTTATCTGAGCATTCAGAGTATATGTCAGGTGTTGTTTCTGATATGATTCTTG
ATTTGATGTCAAGAGGAAAAGATGCTATAGAGGATGTTACCCGGAATATCATGGAACAGTTTGAGATTGATGGAATACGA
ATTTATAATGATAATTCTGAACTTATATATATGTGTGGTGATTATAAGAAAGTTCCGGATATGACCAATATTCTTAAGGA
TGAAGCATTTTTATCAAGATATGGAAAGAACAATTCAATGTCAATCGGTATCGTTCCTTCTGTTGAAGCATGGCATAAAG
GGTTGTTTAATGAGTTATCAGAAAGTAATATCATGGCATTTATAAGTGCATGGTATGAATTCAGATACAGAAGATACTAT
TTCTTTTATGATGTATTTAATCATAAAAACCGCTGGAATGACTCTGACAGGAATTTTGTACTTATTATCAGCAAAATCAT
TGCCAGCGTGTTATAG

Upstream 100 bases:

>100_bases
ATATTTGCCAATAATTTATCAATAATTACAATTTGTCCTAGATAATTAAATGCATTCATGTTAAAATATACATAACATTT
TATGGACGGAGATTGGGGAT

Downstream 100 bases:

>100_bases
ATATATTACGAAATCATACAGTTATTATATTTGGCAGCTTTGCAAAGCTGCCATTTTTTTTATCTGTAATTATAGTTGCA
TCCTTGATATTTCCAAAAGT

Product: two-component system, PleD related family, response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MIISENHFGKENCVAYCDILIRRNYEVINADEHFYHFVEKLVGINFLDIVHPDQLKDFKTTFESLKPGENSRIIILLRNG
IGEYYWSDMYIFNNGKVLSGENILEIRCFFLSAVESRYLMGLDNINKYRTLLSVYRNYLFDYNSYTDIFTIYMYRGNQCT
APVKCPLEQFKDRMLSLLRNDAEKKEFNVFYNYLKTGSNMFSCMVYLPLGENNDELYKFKVNGDSLFANNKHPIVAGYLE
TADGNVNNIIPYYATSEAVDSATGLLNKRACMEYTKAVMASNDNKIHYMIIFDVDNFKSINDTYGHLFGDEVLSKIATIL
NANLNGRGIAGRFGGDEFYIFTSNIKDTEDLRILLTTMRKELQYAFDSRIDEFGVTLSVGVSEYPKDGNNYEILFKKADK
CLYLAKEKGRNRFIIYNEEIHGSIQDNGRHIHKILDLSEHSEYMSGVVSDMILDLMSRGKDAIEDVTRNIMEQFEIDGIR
IYNDNSELIYMCGDYKKVPDMTNILKDEAFLSRYGKNNSMSIGIVPSVEAWHKGLFNELSESNIMAFISAWYEFRYRRYY
FFYDVFNHKNRWNDSDRNFVLIISKIIASVL

Sequences:

>Translated_591_residues
MIISENHFGKENCVAYCDILIRRNYEVINADEHFYHFVEKLVGINFLDIVHPDQLKDFKTTFESLKPGENSRIIILLRNG
IGEYYWSDMYIFNNGKVLSGENILEIRCFFLSAVESRYLMGLDNINKYRTLLSVYRNYLFDYNSYTDIFTIYMYRGNQCT
APVKCPLEQFKDRMLSLLRNDAEKKEFNVFYNYLKTGSNMFSCMVYLPLGENNDELYKFKVNGDSLFANNKHPIVAGYLE
TADGNVNNIIPYYATSEAVDSATGLLNKRACMEYTKAVMASNDNKIHYMIIFDVDNFKSINDTYGHLFGDEVLSKIATIL
NANLNGRGIAGRFGGDEFYIFTSNIKDTEDLRILLTTMRKELQYAFDSRIDEFGVTLSVGVSEYPKDGNNYEILFKKADK
CLYLAKEKGRNRFIIYNEEIHGSIQDNGRHIHKILDLSEHSEYMSGVVSDMILDLMSRGKDAIEDVTRNIMEQFEIDGIR
IYNDNSELIYMCGDYKKVPDMTNILKDEAFLSRYGKNNSMSIGIVPSVEAWHKGLFNELSESNIMAFISAWYEFRYRRYY
FFYDVFNHKNRWNDSDRNFVLIISKIIASVL
>Mature_591_residues
MIISENHFGKENCVAYCDILIRRNYEVINADEHFYHFVEKLVGINFLDIVHPDQLKDFKTTFESLKPGENSRIIILLRNG
IGEYYWSDMYIFNNGKVLSGENILEIRCFFLSAVESRYLMGLDNINKYRTLLSVYRNYLFDYNSYTDIFTIYMYRGNQCT
APVKCPLEQFKDRMLSLLRNDAEKKEFNVFYNYLKTGSNMFSCMVYLPLGENNDELYKFKVNGDSLFANNKHPIVAGYLE
TADGNVNNIIPYYATSEAVDSATGLLNKRACMEYTKAVMASNDNKIHYMIIFDVDNFKSINDTYGHLFGDEVLSKIATIL
NANLNGRGIAGRFGGDEFYIFTSNIKDTEDLRILLTTMRKELQYAFDSRIDEFGVTLSVGVSEYPKDGNNYEILFKKADK
CLYLAKEKGRNRFIIYNEEIHGSIQDNGRHIHKILDLSEHSEYMSGVVSDMILDLMSRGKDAIEDVTRNIMEQFEIDGIR
IYNDNSELIYMCGDYKKVPDMTNILKDEAFLSRYGKNNSMSIGIVPSVEAWHKGLFNELSESNIMAFISAWYEFRYRRYY
FFYDVFNHKNRWNDSDRNFVLIISKIIASVL

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=166, Percent_Identity=31.3253012048193, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082007, Length=160, Percent_Identity=36.25, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786584, Length=129, Percent_Identity=35.6589147286822, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=32.9268292682927, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=30.2469135802469, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=28.6585365853659, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787802, Length=196, Percent_Identity=30.1020408163265, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI87081881, Length=158, Percent_Identity=34.1772151898734, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787056, Length=193, Percent_Identity=30.5699481865285, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788381, Length=172, Percent_Identity=27.3255813953488, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788085, Length=161, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081977, Length=171, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=31.6455696202532, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 68741; Mature: 68741

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIISENHFGKENCVAYCDILIRRNYEVINADEHFYHFVEKLVGINFLDIVHPDQLKDFKT
CEECCCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCEEECCCCHHHHHHHH
TFESLKPGENSRIIILLRNGIGEYYWSDMYIFNNGKVLSGENILEIRCFFLSAVESRYLM
HHHHCCCCCCCEEEEEEECCCCCCEECCEEEEECCEEECCCCEEEHHHHHHHHHHHHHHC
GLDNINKYRTLLSVYRNYLFDYNSYTDIFTIYMYRGNQCTAPVKCPLEQFKDRMLSLLRN
CCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHC
DAEKKEFNVFYNYLKTGSNMFSCMVYLPLGENNDELYKFKVNGDSLFANNKHPIVAGYLE
CCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEEEECCCEEEECCCCCEEEEEEE
TADGNVNNIIPYYATSEAVDSATGLLNKRACMEYTKAVMASNDNKIHYMIIFDVDNFKSI
CCCCCCCCEECEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCC
NDTYGHLFGDEVLSKIATILNANLNGRGIAGRFGGDEFYIFTSNIKDTEDLRILLTTMRK
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHH
ELQYAFDSRIDEFGVTLSVGVSEYPKDGNNYEILFKKADKCLYLAKEKGRNRFIIYNEEI
HHHHHHHCCHHHCCCEEEECCCCCCCCCCCEEEEEEECCCEEEEEHHCCCCEEEEEECCC
HGSIQDNGRHIHKILDLSEHSEYMSGVVSDMILDLMSRGKDAIEDVTRNIMEQFEIDGIR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
IYNDNSELIYMCGDYKKVPDMTNILKDEAFLSRYGKNNSMSIGIVPSVEAWHKGLFNELS
EEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHC
ESNIMAFISAWYEFRYRRYYFFYDVFNHKNRWNDSDRNFVLIISKIIASVL
CCHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHC
>Mature Secondary Structure
MIISENHFGKENCVAYCDILIRRNYEVINADEHFYHFVEKLVGINFLDIVHPDQLKDFKT
CEECCCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCEEECCCCHHHHHHHH
TFESLKPGENSRIIILLRNGIGEYYWSDMYIFNNGKVLSGENILEIRCFFLSAVESRYLM
HHHHCCCCCCCEEEEEEECCCCCCEECCEEEEECCEEECCCCEEEHHHHHHHHHHHHHHC
GLDNINKYRTLLSVYRNYLFDYNSYTDIFTIYMYRGNQCTAPVKCPLEQFKDRMLSLLRN
CCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHC
DAEKKEFNVFYNYLKTGSNMFSCMVYLPLGENNDELYKFKVNGDSLFANNKHPIVAGYLE
CCCHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEEEEEECCCEEEECCCCCEEEEEEE
TADGNVNNIIPYYATSEAVDSATGLLNKRACMEYTKAVMASNDNKIHYMIIFDVDNFKSI
CCCCCCCCEECEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCC
NDTYGHLFGDEVLSKIATILNANLNGRGIAGRFGGDEFYIFTSNIKDTEDLRILLTTMRK
CHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHH
ELQYAFDSRIDEFGVTLSVGVSEYPKDGNNYEILFKKADKCLYLAKEKGRNRFIIYNEEI
HHHHHHHCCHHHCCCEEEECCCCCCCCCCCEEEEEEECCCEEEEEHHCCCCEEEEEECCC
HGSIQDNGRHIHKILDLSEHSEYMSGVVSDMILDLMSRGKDAIEDVTRNIMEQFEIDGIR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEE
IYNDNSELIYMCGDYKKVPDMTNILKDEAFLSRYGKNNSMSIGIVPSVEAWHKGLFNELS
EEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHC
ESNIMAFISAWYEFRYRRYYFFYDVFNHKNRWNDSDRNFVLIISKIIASVL
CCHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]