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The map label for this gene is cbiC [H]

Identifier: 238921953

GI number: 238921953

Start: 151233

End: 151865

Strand: Reverse

Name: cbiC [H]

Synonym: EUBELI_20187

Alternate gene names: 238921953

Gene position: 151865-151233 (Counterclockwise)

Preceding gene: 238921954

Following gene: 238921952

Centisome position: 24.23

GC content: 41.71

Gene sequence:

>633_bases
ATGAAGCCAATGGATATTGAAAAACAGTCGTTTGCAATAATTGAAAAAGAACTTACAACAGATATTCCACCTGAATACAA
GCCGGTTGTTAAGAGAGTTATTCATACAACAGCGGACTTTTCATATGAGACAAGCATGATGTTTTCAGATGGCGTTATAG
AGAAAGCACTGATGGCAATACGTGAGGGTACGGAGATTGTGACCGATACCAACATGGCAAAATCAGGTATAAGTCATAAG
ATAGCTGAAAAATTCGGCTGCTCACTTAACTGTTATATGGCAGATGAAGGTGTTGCAAAAGAAGCTGCAAGCCGTGAGAC
AACAAGGGCAGTGGTCAGTGTGGAGAAGGCGGCAAAGGACAATCCGGGATGTATTATGGTAGTTGGAAATGCGCCAACAG
CACTTATGAGAATAAGAGAACTGTATGATGAAGGTACATTTGCTCCAAGACTGGTTATCGGAGTTCCGGTTGGGTTTGTA
AATGTAGTTGAGGCAAAAGAAGAAATAATTGAAAGCGGTATGCCATATATAGTTGCAAGAGGCAGAAAAGGCGGAAGCAA
TGTTGCGGCGGCAATTATGAACGCATTGTTTTATATGGCAGCAGATGATGATAAAGAGTGGCGCAGATGTTAG

Upstream 100 bases:

>100_bases
TAAAGGATGTACTGGAGTATGCAGCAGAAAAGAAAAAAATTATTCTTAAAAAACCAGACATAGATACATTGAAATCATTA
TTCACAGGAGAATAGATATT

Downstream 100 bases:

>100_bases
AGAGATATGTATATAAGAATCAGAAAAAAATGCGATGTGGATATACAACAGGAACATGTGCATGCGCAGCGGCGAAAGCG
GCGGCATGTATGCTTTTGTC

Product: precorrin-8X methylmutase

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKPMDIEKQSFAIIEKELTTDIPPEYKPVVKRVIHTTADFSYETSMMFSDGVIEKALMAIREGTEIVTDTNMAKSGISHK
IAEKFGCSLNCYMADEGVAKEAASRETTRAVVSVEKAAKDNPGCIMVVGNAPTALMRIRELYDEGTFAPRLVIGVPVGFV
NVVEAKEEIIESGMPYIVARGRKGGSNVAAAIMNALFYMAADDDKEWRRC

Sequences:

>Translated_210_residues
MKPMDIEKQSFAIIEKELTTDIPPEYKPVVKRVIHTTADFSYETSMMFSDGVIEKALMAIREGTEIVTDTNMAKSGISHK
IAEKFGCSLNCYMADEGVAKEAASRETTRAVVSVEKAAKDNPGCIMVVGNAPTALMRIRELYDEGTFAPRLVIGVPVGFV
NVVEAKEEIIESGMPYIVARGRKGGSNVAAAIMNALFYMAADDDKEWRRC
>Mature_210_residues
MKPMDIEKQSFAIIEKELTTDIPPEYKPVVKRVIHTTADFSYETSMMFSDGVIEKALMAIREGTEIVTDTNMAKSGISHK
IAEKFGCSLNCYMADEGVAKEAASRETTRAVVSVEKAAKDNPGCIMVVGNAPTALMRIRELYDEGTFAPRLVIGVPVGFV
NVVEAKEEIIESGMPYIVARGRKGGSNVAAAIMNALFYMAADDDKEWRRC

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 23040; Mature: 23040

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPMDIEKQSFAIIEKELTTDIPPEYKPVVKRVIHTTADFSYETSMMFSDGVIEKALMAI
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
REGTEIVTDTNMAKSGISHKIAEKFGCSLNCYMADEGVAKEAASRETTRAVVSVEKAAKD
HCCCCEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
NPGCIMVVGNAPTALMRIRELYDEGTFAPRLVIGVPVGFVNVVEAKEEIIESGMPYIVAR
CCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEE
GRKGGSNVAAAIMNALFYMAADDDKEWRRC
CCCCCHHHHHHHHHHHHHHCCCCCHHHHCC
>Mature Secondary Structure
MKPMDIEKQSFAIIEKELTTDIPPEYKPVVKRVIHTTADFSYETSMMFSDGVIEKALMAI
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
REGTEIVTDTNMAKSGISHKIAEKFGCSLNCYMADEGVAKEAASRETTRAVVSVEKAAKD
HCCCCEEECCCHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
NPGCIMVVGNAPTALMRIRELYDEGTFAPRLVIGVPVGFVNVVEAKEEIIESGMPYIVAR
CCCEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCEEEEE
GRKGGSNVAAAIMNALFYMAADDDKEWRRC
CCCCCHHHHHHHHHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 1451790 [H]