| Definition | Eubacterium eligens ATCC 27750 plasmid unnamed, complete sequence. |
|---|---|
| Accession | NC_012780 |
| Length | 626,744 |
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The map label for this gene is yqhE [C]
Identifier: 238921930
GI number: 238921930
Start: 129130
End: 129948
Strand: Reverse
Name: yqhE [C]
Synonym: EUBELI_20164
Alternate gene names: 238921930
Gene position: 129948-129130 (Counterclockwise)
Preceding gene: 238921931
Following gene: 238921928
Centisome position: 20.73
GC content: 38.95
Gene sequence:
>819_bases ATGAATTATATTACATTAAATAATGGAGTTAAAATTCCACAGATAGGTCTTGGTGTTTTTAGAACACCAGACGGAGCTGA TACAGCTAATGCAGTAAAATGGGCGATTGAGGCTGGATACAGACATATTGATACAGCTAAGGTTTACGGCAATGAAAAAA GCGTAGGCGAAGGCATACGTATGAGTGGCATTGACAGAAGGGATATATTTGTTACAACTAAGCTTTGGAATGAGGATATT AGACAGGGAAGAACTAAAGAAGCATTTTTACAGAGCTTGGAAGACATGGGACTTGATTACATAGACTTGTATCTTATTCA CTGGCCAGCTAACGGTTATGAGAAGGCGTGGGCAGATATGGAGGACCTGTACAAGGCTGGCAAAATCAAGGCAATCGGTG TAAGTAACTTCAATGTTCACCATCTTGAGACTCTCAGTGAAAACTGGACAGTTGTACCAGCGGTTAACCAGATTGAGATT CATCCTTATTACGCTAATATTGAAAATGTTGAATATGCTAAGAAGAATGGTATTGCAATAGAAGCCTACAGCCCACTTGG AGGCAACGGAGCAGGAACACTTGAAAATGAGGTGATTATTGCACTGGCTGACAAGTATGGTAAGACACCTGCACAGATTG TTTTAAGATGGGAGCTTCAGAGAGGAATAATTGTACTTCCAAAGTCAACGCATCAGGAAAGAATTATTTCTAATTTTGAC GTGTTTGATTTTGAATTGTCTGATGGTGATATGAATGCCATAAATGAGCTTAACAAGAACGAAAAACACGGTTCTGACCC AGAAACATTTAATTTTTAA
Upstream 100 bases:
>100_bases TCATATCAATTTTGAGGTAAGAGGACTCAATACTATAATTGAAATTGAACGTTTACATGGTGTAAAATGAAAGAAAACAG ATAAAGGAGATTTGAATTAT
Downstream 100 bases:
>100_bases GAGGAACTTGACTTTTGAATCGGTTTAAAAATCGAAACACGGCACAAAGCACCGAATATTCTAATCAACCAGTCCCTTGT TCTTCCACTTTCCGCTCTTC
Product: 2,5-diketo-D-gluconate reductase
Products: 2-keto-L-gulonate; NADP [C]
Alternate protein names: NA
Number of amino acids: Translated: 272; Mature: 272
Protein sequence:
>272_residues MNYITLNNGVKIPQIGLGVFRTPDGADTANAVKWAIEAGYRHIDTAKVYGNEKSVGEGIRMSGIDRRDIFVTTKLWNEDI RQGRTKEAFLQSLEDMGLDYIDLYLIHWPANGYEKAWADMEDLYKAGKIKAIGVSNFNVHHLETLSENWTVVPAVNQIEI HPYYANIENVEYAKKNGIAIEAYSPLGGNGAGTLENEVIIALADKYGKTPAQIVLRWELQRGIIVLPKSTHQERIISNFD VFDFELSDGDMNAINELNKNEKHGSDPETFNF
Sequences:
>Translated_272_residues MNYITLNNGVKIPQIGLGVFRTPDGADTANAVKWAIEAGYRHIDTAKVYGNEKSVGEGIRMSGIDRRDIFVTTKLWNEDI RQGRTKEAFLQSLEDMGLDYIDLYLIHWPANGYEKAWADMEDLYKAGKIKAIGVSNFNVHHLETLSENWTVVPAVNQIEI HPYYANIENVEYAKKNGIAIEAYSPLGGNGAGTLENEVIIALADKYGKTPAQIVLRWELQRGIIVLPKSTHQERIISNFD VFDFELSDGDMNAINELNKNEKHGSDPETFNF >Mature_272_residues MNYITLNNGVKIPQIGLGVFRTPDGADTANAVKWAIEAGYRHIDTAKVYGNEKSVGEGIRMSGIDRRDIFVTTKLWNEDI RQGRTKEAFLQSLEDMGLDYIDLYLIHWPANGYEKAWADMEDLYKAGKIKAIGVSNFNVHHLETLSENWTVVPAVNQIEI HPYYANIENVEYAKKNGIAIEAYSPLGGNGAGTLENEVIIALADKYGKTPAQIVLRWELQRGIIVLPKSTHQERIISNFD VFDFELSDGDMNAINELNKNEKHGSDPETFNF
Specific function: Reduction [C]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=296, Percent_Identity=38.5135135135135, Blast_Score=221, Evalue=4e-58, Organism=Homo sapiens, GI5174391, Length=296, Percent_Identity=38.5135135135135, Blast_Score=221, Evalue=4e-58, Organism=Homo sapiens, GI223468663, Length=295, Percent_Identity=37.6271186440678, Blast_Score=202, Evalue=2e-52, Organism=Homo sapiens, GI310109922, Length=277, Percent_Identity=39.7111913357401, Blast_Score=199, Evalue=2e-51, Organism=Homo sapiens, GI310109920, Length=298, Percent_Identity=37.9194630872483, Blast_Score=195, Evalue=3e-50, Organism=Homo sapiens, GI45446745, Length=298, Percent_Identity=38.255033557047, Blast_Score=195, Evalue=3e-50, Organism=Homo sapiens, GI4503285, Length=298, Percent_Identity=38.255033557047, Blast_Score=195, Evalue=3e-50, Organism=Homo sapiens, GI5453543, Length=298, Percent_Identity=37.5838926174497, Blast_Score=194, Evalue=6e-50, Organism=Homo sapiens, GI24497583, Length=295, Percent_Identity=38.3050847457627, Blast_Score=192, Evalue=2e-49, Organism=Homo sapiens, GI4502049, Length=293, Percent_Identity=41.296928327645, Blast_Score=191, Evalue=7e-49, Organism=Homo sapiens, GI93277124, Length=308, Percent_Identity=36.3636363636364, Blast_Score=191, Evalue=9e-49, Organism=Homo sapiens, GI24497585, Length=298, Percent_Identity=36.5771812080537, Blast_Score=189, Evalue=2e-48, Organism=Homo sapiens, GI5174695, Length=297, Percent_Identity=38.7205387205387, Blast_Score=186, Evalue=2e-47, Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=36.6037735849057, Blast_Score=176, Evalue=3e-44, Organism=Homo sapiens, GI300116273, Length=278, Percent_Identity=38.1294964028777, Blast_Score=167, Evalue=1e-41, Organism=Homo sapiens, GI300116271, Length=274, Percent_Identity=36.1313868613139, Blast_Score=161, Evalue=5e-40, Organism=Homo sapiens, GI310109924, Length=155, Percent_Identity=40.6451612903226, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI207028673, Length=117, Percent_Identity=41.8803418803419, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI310109926, Length=117, Percent_Identity=41.025641025641, Blast_Score=94, Evalue=2e-19, Organism=Escherichia coli, GI87082198, Length=270, Percent_Identity=44.8148148148148, Blast_Score=245, Evalue=3e-66, Organism=Escherichia coli, GI1786400, Length=268, Percent_Identity=37.3134328358209, Blast_Score=166, Evalue=2e-42, Organism=Escherichia coli, GI1788081, Length=272, Percent_Identity=29.0441176470588, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI1787674, Length=265, Percent_Identity=24.1509433962264, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI1788070, Length=284, Percent_Identity=23.943661971831, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17537077, Length=291, Percent_Identity=37.8006872852234, Blast_Score=191, Evalue=5e-49, Organism=Caenorhabditis elegans, GI17537075, Length=290, Percent_Identity=37.9310344827586, Blast_Score=189, Evalue=1e-48, Organism=Caenorhabditis elegans, GI71998625, Length=267, Percent_Identity=38.5767790262172, Blast_Score=189, Evalue=1e-48, Organism=Caenorhabditis elegans, GI17550248, Length=292, Percent_Identity=35.6164383561644, Blast_Score=187, Evalue=4e-48, Organism=Caenorhabditis elegans, GI17564128, Length=300, Percent_Identity=36.3333333333333, Blast_Score=179, Evalue=1e-45, Organism=Caenorhabditis elegans, GI17561298, Length=275, Percent_Identity=33.8181818181818, Blast_Score=177, Evalue=5e-45, Organism=Caenorhabditis elegans, GI17566692, Length=294, Percent_Identity=37.7551020408163, Blast_Score=176, Evalue=9e-45, Organism=Caenorhabditis elegans, GI17552492, Length=273, Percent_Identity=32.2344322344322, Blast_Score=156, Evalue=1e-38, Organism=Caenorhabditis elegans, GI17537079, Length=294, Percent_Identity=30.2721088435374, Blast_Score=154, Evalue=6e-38, Organism=Caenorhabditis elegans, GI17561300, Length=272, Percent_Identity=33.8235294117647, Blast_Score=151, Evalue=4e-37, Organism=Caenorhabditis elegans, GI17538386, Length=271, Percent_Identity=33.210332103321, Blast_Score=143, Evalue=8e-35, Organism=Caenorhabditis elegans, GI17562292, Length=275, Percent_Identity=29.0909090909091, Blast_Score=137, Evalue=5e-33, Organism=Saccharomyces cerevisiae, GI6320576, Length=293, Percent_Identity=40.9556313993174, Blast_Score=216, Evalue=2e-57, Organism=Saccharomyces cerevisiae, GI6324694, Length=289, Percent_Identity=41.1764705882353, Blast_Score=215, Evalue=5e-57, Organism=Saccharomyces cerevisiae, GI6322556, Length=266, Percent_Identity=38.7218045112782, Blast_Score=175, Evalue=7e-45, Organism=Saccharomyces cerevisiae, GI6321896, Length=317, Percent_Identity=36.9085173501577, Blast_Score=172, Evalue=4e-44, Organism=Saccharomyces cerevisiae, GI6319625, Length=294, Percent_Identity=35.0340136054422, Blast_Score=165, Evalue=8e-42, Organism=Saccharomyces cerevisiae, GI6320079, Length=282, Percent_Identity=35.4609929078014, Blast_Score=150, Evalue=2e-37, Organism=Drosophila melanogaster, GI24657054, Length=292, Percent_Identity=41.0958904109589, Blast_Score=199, Evalue=1e-51, Organism=Drosophila melanogaster, GI24662789, Length=291, Percent_Identity=38.1443298969072, Blast_Score=190, Evalue=1e-48, Organism=Drosophila melanogaster, GI21356425, Length=292, Percent_Identity=39.3835616438356, Blast_Score=189, Evalue=2e-48, Organism=Drosophila melanogaster, GI24644950, Length=299, Percent_Identity=35.7859531772575, Blast_Score=186, Evalue=1e-47, Organism=Drosophila melanogaster, GI20129731, Length=286, Percent_Identity=36.7132867132867, Blast_Score=184, Evalue=4e-47, Organism=Drosophila melanogaster, GI24663317, Length=291, Percent_Identity=37.1134020618557, Blast_Score=182, Evalue=2e-46, Organism=Drosophila melanogaster, GI221378297, Length=319, Percent_Identity=33.5423197492163, Blast_Score=179, Evalue=2e-45, Organism=Drosophila melanogaster, GI24662781, Length=277, Percent_Identity=42.9602888086643, Blast_Score=177, Evalue=7e-45, Organism=Drosophila melanogaster, GI24662785, Length=277, Percent_Identity=42.9602888086643, Blast_Score=176, Evalue=1e-44, Organism=Drosophila melanogaster, GI45553081, Length=290, Percent_Identity=35.1724137931034, Blast_Score=173, Evalue=9e-44, Organism=Drosophila melanogaster, GI281366140, Length=255, Percent_Identity=34.9019607843137, Blast_Score=154, Evalue=7e-38,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: NA
Molecular weight: Translated: 30593; Mature: 30593
Theoretical pI: Translated: 4.84; Mature: 4.84
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2 ; PS00063 ALDOKETO_REDUCTASE_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNYITLNNGVKIPQIGLGVFRTPDGADTANAVKWAIEAGYRHIDTAKVYGNEKSVGEGIR CCEEEECCCCCCCEECCEEEECCCCCCCHHHHHHHHHHCCEEECEEEEECCCCCCCCCCE MSGIDRRDIFVTTKLWNEDIRQGRTKEAFLQSLEDMGLDYIDLYLIHWPANGYEKAWADM ECCCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHCCH EDLYKAGKIKAIGVSNFNVHHLETLSENWTVVPAVNQIEIHPYYANIENVEYAKKNGIAI HHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEECCEEEEEEEECCCCCCEEHHHCCEEE EAYSPLGGNGAGTLENEVIIALADKYGKTPAQIVLRWELQRGIIVLPKSTHQERIISNFD EEECCCCCCCCCCCCCCEEEEEECCCCCCHHHEEEEEEECCCEEEEECCCCHHHHHCCCC VFDFELSDGDMNAINELNKNEKHGSDPETFNF EEEEEECCCCHHHHHHCCCCCCCCCCCCCCCC >Mature Secondary Structure MNYITLNNGVKIPQIGLGVFRTPDGADTANAVKWAIEAGYRHIDTAKVYGNEKSVGEGIR CCEEEECCCCCCCEECCEEEECCCCCCCHHHHHHHHHHCCEEECEEEEECCCCCCCCCCE MSGIDRRDIFVTTKLWNEDIRQGRTKEAFLQSLEDMGLDYIDLYLIHWPANGYEKAWADM ECCCCCCEEEEEEHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHCCH EDLYKAGKIKAIGVSNFNVHHLETLSENWTVVPAVNQIEIHPYYANIENVEYAKKNGIAI HHHHHCCCEEEEECCCCCEEEEECCCCCCEEEEECCEEEEEEEECCCCCCEEHHHCCEEE EAYSPLGGNGAGTLENEVIIALADKYGKTPAQIVLRWELQRGIIVLPKSTHQERIISNFD EEECCCCCCCCCCCCCCEEEEEECCCCCCHHHEEEEEEECCCEEEEECCCCHHHHHCCCC VFDFELSDGDMNAINELNKNEKHGSDPETFNF EEEEEECCCCHHHHHHCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: 2,5-diketo-D-gluconate; NADPH [C]
Specific reaction: 2,5-diketo-D-gluconate + NADPH = 2-keto-L-gulonate + NADP [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA