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The map label for this gene is rnpA

Identifier: 238921765

GI number: 238921765

Start: 3811135

End: 3811494

Strand: Reverse

Name: rnpA

Synonym: NT01EI_3934

Alternate gene names: 238921765

Gene position: 3811494-3811135 (Counterclockwise)

Preceding gene: 238921766

Following gene: 238921764

Centisome position: 99.98

GC content: 52.22

Gene sequence:

>360_bases
GTGGTTAAGCTAAGTTTCCCTAGGGAGTTACGTTTGTTAACTCCCAATCACTTCAATTTCGTCTTCCAGCAACCGCAACG
AGCCGGTACGCCCCAACTTACCATTCTCGGCCGTATGAACTCGCTGGGGTATCCCCGCATCGGTCTTACTGTCGCCAAAA
AGCATGTCAAACGCGCTCATGAGCGTAACCGTATCAAGCGCCTGACACGCGAAAGTTTCCGTCTGCGTCAGCATTCGCTG
CCAGCTATGGACTTTGTGGTAATCGTCAAAAAGGGTGTTCAGGAACTCGATAATCGGGCGCTGACAGAGATGTTGGAAAA
ATTATGGCGTCGCCATTGTCGCCAGGCTCGCGCCTCCTGA

Upstream 100 bases:

>100_bases
CCCGTATGGCAAATAAAAATGGCCGTCAGGTTCTTGCCCGTCGCCGCGCTAAAGGCCGCGCTCGTCTGACCGTAGCCGGT
TAATTTAGCTGACCAGATTA

Downstream 100 bases:

>100_bases
TTGCGCTGATACGTGGTTATCAGCGCTTTATCAGTCCGCTGCTTGGGCCACACTGCCGCTTCCATCCTACCTGCTCACAG
TACGGAATTGAGGCATTGCG

Product: ribonuclease P protein component

Products: NA

Alternate protein names: RNase P protein; RNaseP protein; Protein C5

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MVKLSFPRELRLLTPNHFNFVFQQPQRAGTPQLTILGRMNSLGYPRIGLTVAKKHVKRAHERNRIKRLTRESFRLRQHSL
PAMDFVVIVKKGVQELDNRALTEMLEKLWRRHCRQARAS

Sequences:

>Translated_119_residues
MVKLSFPRELRLLTPNHFNFVFQQPQRAGTPQLTILGRMNSLGYPRIGLTVAKKHVKRAHERNRIKRLTRESFRLRQHSL
PAMDFVVIVKKGVQELDNRALTEMLEKLWRRHCRQARAS
>Mature_119_residues
MVKLSFPRELRLLTPNHFNFVFQQPQRAGTPQLTILGRMNSLGYPRIGLTVAKKHVKRAHERNRIKRLTRESFRLRQHSL
PAMDFVVIVKKGVQELDNRALTEMLEKLWRRHCRQARAS

Specific function: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-lead

COG id: COG0594

COG function: function code J; RNase P protein component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rnpA family

Homologues:

Organism=Escherichia coli, GI1790139, Length=119, Percent_Identity=84.8739495798319, Blast_Score=213, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNPA_EDWI9 (C5BF62)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002935280.1
- GeneID:   7961500
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3934
- OMA:   LVIGKKS
- HAMAP:   MF_00227
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR000100
- InterPro:   IPR020539
- Gene3D:   G3DSA:3.30.230.10
- ProDom:   PD003629
- TIGRFAMs:   TIGR00188

Pfam domain/function: PF00825 Ribonuclease_P; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =3.1.26.5

Molecular weight: Translated: 14068; Mature: 14068

Theoretical pI: Translated: 12.27; Mature: 12.27

Prosite motif: PS00648 RIBONUCLEASE_P

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLSFPRELRLLTPNHFNFVFQQPQRAGTPQLTILGRMNSLGYPRIGLTVAKKHVKRAH
CCCCCCCCCEEEECCCCCHHEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
ERNRIKRLTRESFRLRQHSLPAMDFVVIVKKGVQELDNRALTEMLEKLWRRHCRQARAS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKLSFPRELRLLTPNHFNFVFQQPQRAGTPQLTILGRMNSLGYPRIGLTVAKKHVKRAH
CCCCCCCCCEEEECCCCCHHEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
ERNRIKRLTRESFRLRQHSLPAMDFVVIVKKGVQELDNRALTEMLEKLWRRHCRQARAS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA