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The map label for this gene is ade

Identifier: 238921755

GI number: 238921755

Start: 3801588

End: 3803363

Strand: Reverse

Name: ade

Synonym: NT01EI_3924

Alternate gene names: 238921755

Gene position: 3803363-3801588 (Counterclockwise)

Preceding gene: 238921758

Following gene: 238921754

Centisome position: 99.77

GC content: 60.3

Gene sequence:

>1776_bases
ATGGAAGATATTCATCACAAACATACGCAATCGGTTTCCCGCTCTGATATGCTGCGTCTTCTGGCCGTTTCACGTGGCGA
TCAGCCTGCAGACCTCATCATCGATAATGTTTTCCTGCTGGATCTCATCAACGGCGGAACCCTGCCGGGTCCCATTCTCA
TCAGCGGTGACAGCATTGCCGGCGTCGGGCCGGCCTATGCCGGTACCGCGGCCCTGGAGCGCATTGACGCCGGCGGTGCC
ATCGCCGTTCCCGGCTTTATCGACGCCCACCTGCACATCGAGTCCAGCATGATGACCCCCATCGCCTTCGAAAGCGTCAC
GTTGCCCCTCGGCGTCACCACTATCGTATGCGACCCCCATGAAATCGTTAACGTGATGGGGGAAAAGGGGCTGACATGGT
TCCTGCGCTGTGCCGAGGGTGCACAGCAAAACCAGTTCATACAGATCAGCTCCTGTGTGCCGGCACTGGCCGGAACCGAT
ATCAACGGTGCAGAGTTCCCCCTGACAGCAATGCTGCCCTATCGTGAGCATCCCCATGTGCTGGGACTGGCAGAGATGAT
GAACTTTCCCGGCGTCATTGCCGGCGATGAGCCTACTCTCGATAAGCTGGATGCGTTCCGCCACCTGACGCTGGACGGCC
ATAGCCCCATGCTGAGCGGCAAAGCGCTGAATGCCTATCTGGCCGCCGGCGTGGAAAACTGCCATGAGACACTGGCGCTG
GAAGAGGGACGGGAAAAGCTGGCACTGGGCATGGCGCTGATGATCCGCGAAGGCTCCGCGGCGCGTAACCTGGATACGCT
GGCGCCTCTGATCAGCGAGTTCAATAGCCCGCAGTGCATGCTGTGCACCGATGACAGGAATCCATGGGAGATCGCGCACG
AAGGGCACATTGATGCGCTGATCCGGCGCCTGATCCAACGGCATCACATCGCGCCACACGTAGCATACCGCGTCGCCAGC
TGGTCGGCGGCGCGCCACTTTGGTCTCAAGCGCCTGGGGTTGATCGCCCCGGGGAAAAAGGCAGATATTGTCCTGCTGGA
TAACCTTGAGCAGGTGGCCATTCGCCAGGTATTTGCTGGCGGTAAGGCCATCGATGCACAGCAGCTGCTGCGCAGCGCAG
CGATGCGCCAGCTGGCCAGCTGCCCGCCGCAGCACAATACCCTACGGCGAGCCCCACTCAGCGCTGAGGATCTGACGCTA
CCCCTGACGCAGGATGCCGACTATCGCGCCATTCAGCTAATCCCCAACGAGCTCATCACCCCGGCCAGGACGGTACGCTG
GCTGGGCGATGGCTTCGATACGCCAGACGTATGCCGCATTGCGGTGATGGAACGCTATGGTCAGCAGAGGGTGCCAGCGC
TGGGCCTTCTTCACAATAGCGGCCTGAGCAAAGGAGCACTGGCGGCCACCGTCAGCCACGACAGCCACAATATTGTGGTC
ATCGGCCACCATCCGGCAGAGATGGCACTGGCGGTCAATCAGCTGATTGACGACGGCGGCGGACTGTGTGTCGTTGCCGA
CGGACAGGTCGTAGTCCATCTGCCGCTGCCCATCGCCGGCCTGATGAGCTCACGATCGGCGGCAGAGATTGCCGATATCA
TCGATGCGCTGAAACAGGCCTGCCGCAACTGCGGCATGACCCTGAATGAACCGTTTATTCAGATGGCGTTTCTCTCGCTG
CCGGTGATCCCATCGCTCAAGCTGACCAGTCTTGGGCTGTATGATGTAGACCACTTCCGCTTTACCGAGGTTCGCATACC
GGAAGAGAGCGCTTAA

Upstream 100 bases:

>100_bases
GATGTAACGCAAACGCTTATATACATAAAATTGCTACAATAGACATGTGAAAACGCTTTAATATCAAAATGATAAAATAA
ATATCTGTAAGGTGAACCAC

Downstream 100 bases:

>100_bases
ACTAGGACAAAAATAACGTTGATACGGCGCGGACATCTCCGCGCCGACCGGCCAAAAAGGACGCCCATGAGCAGTATCCG
CTGTATTCTCTTCGACTGTG

Product: cryptic adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MEDIHHKHTQSVSRSDMLRLLAVSRGDQPADLIIDNVFLLDLINGGTLPGPILISGDSIAGVGPAYAGTAALERIDAGGA
IAVPGFIDAHLHIESSMMTPIAFESVTLPLGVTTIVCDPHEIVNVMGEKGLTWFLRCAEGAQQNQFIQISSCVPALAGTD
INGAEFPLTAMLPYREHPHVLGLAEMMNFPGVIAGDEPTLDKLDAFRHLTLDGHSPMLSGKALNAYLAAGVENCHETLAL
EEGREKLALGMALMIREGSAARNLDTLAPLISEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIQRHHIAPHVAYRVAS
WSAARHFGLKRLGLIAPGKKADIVLLDNLEQVAIRQVFAGGKAIDAQQLLRSAAMRQLASCPPQHNTLRRAPLSAEDLTL
PLTQDADYRAIQLIPNELITPARTVRWLGDGFDTPDVCRIAVMERYGQQRVPALGLLHNSGLSKGALAATVSHDSHNIVV
IGHHPAEMALAVNQLIDDGGGLCVVADGQVVVHLPLPIAGLMSSRSAAEIADIIDALKQACRNCGMTLNEPFIQMAFLSL
PVIPSLKLTSLGLYDVDHFRFTEVRIPEESA

Sequences:

>Translated_591_residues
MEDIHHKHTQSVSRSDMLRLLAVSRGDQPADLIIDNVFLLDLINGGTLPGPILISGDSIAGVGPAYAGTAALERIDAGGA
IAVPGFIDAHLHIESSMMTPIAFESVTLPLGVTTIVCDPHEIVNVMGEKGLTWFLRCAEGAQQNQFIQISSCVPALAGTD
INGAEFPLTAMLPYREHPHVLGLAEMMNFPGVIAGDEPTLDKLDAFRHLTLDGHSPMLSGKALNAYLAAGVENCHETLAL
EEGREKLALGMALMIREGSAARNLDTLAPLISEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIQRHHIAPHVAYRVAS
WSAARHFGLKRLGLIAPGKKADIVLLDNLEQVAIRQVFAGGKAIDAQQLLRSAAMRQLASCPPQHNTLRRAPLSAEDLTL
PLTQDADYRAIQLIPNELITPARTVRWLGDGFDTPDVCRIAVMERYGQQRVPALGLLHNSGLSKGALAATVSHDSHNIVV
IGHHPAEMALAVNQLIDDGGGLCVVADGQVVVHLPLPIAGLMSSRSAAEIADIIDALKQACRNCGMTLNEPFIQMAFLSL
PVIPSLKLTSLGLYDVDHFRFTEVRIPEESA
>Mature_591_residues
MEDIHHKHTQSVSRSDMLRLLAVSRGDQPADLIIDNVFLLDLINGGTLPGPILISGDSIAGVGPAYAGTAALERIDAGGA
IAVPGFIDAHLHIESSMMTPIAFESVTLPLGVTTIVCDPHEIVNVMGEKGLTWFLRCAEGAQQNQFIQISSCVPALAGTD
INGAEFPLTAMLPYREHPHVLGLAEMMNFPGVIAGDEPTLDKLDAFRHLTLDGHSPMLSGKALNAYLAAGVENCHETLAL
EEGREKLALGMALMIREGSAARNLDTLAPLISEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIQRHHIAPHVAYRVAS
WSAARHFGLKRLGLIAPGKKADIVLLDNLEQVAIRQVFAGGKAIDAQQLLRSAAMRQLASCPPQHNTLRRAPLSAEDLTL
PLTQDADYRAIQLIPNELITPARTVRWLGDGFDTPDVCRIAVMERYGQQRVPALGLLHNSGLSKGALAATVSHDSHNIVV
IGHHPAEMALAVNQLIDDGGGLCVVADGQVVVHLPLPIAGLMSSRSAAEIADIIDALKQACRNCGMTLNEPFIQMAFLSL
PVIPSLKLTSLGLYDVDHFRFTEVRIPEESA

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=585, Percent_Identity=65.982905982906, Blast_Score=782, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_EDWI9 (C5BF52)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002935270.1
- GeneID:   7961490
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3924
- OMA:   GKIITEH
- ProtClustDB:   PRK10027
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 63676; Mature: 63676

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDIHHKHTQSVSRSDMLRLLAVSRGDQPADLIIDNVFLLDLINGGTLPGPILISGDSIA
CCCCCHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCCCCCEEEECCCCC
GVGPAYAGTAALERIDAGGAIAVPGFIDAHLHIESSMMTPIAFESVTLPLGVTTIVCDPH
CCCCHHHHHHHHHHHCCCCEEECCCEEEEEEEECCCCCCCEEECEEEECCCEEEEEECHH
EIVNVMGEKGLTWFLRCAEGAQQNQFIQISSCVPALAGTDINGAEFPLTAMLPYREHPHV
HHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCHHCCCCCCCCCCCEEEECCCCCCCCE
LGLAEMMNFPGVIAGDEPTLDKLDAFRHLTLDGHSPMLSGKALNAYLAAGVENCHETLAL
EEHHHHHCCCCEEECCCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EEGREKLALGMALMIREGSAARNLDTLAPLISEFNSPQCMLCTDDRNPWEIAHEGHIDAL
HHCHHHHHHCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCHHHH
IRRLIQRHHIAPHVAYRVASWSAARHFGLKRLGLIAPGKKADIVLLDNLEQVAIRQVFAG
HHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHCEECCCCCCCEEEECCHHHHHHHHHHCC
GKAIDAQQLLRSAAMRQLASCPPQHNTLRRAPLSAEDLTLPLTQDADYRAIQLIPNELIT
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCEEEECCCCCCCEEEEECCHHHCC
PARTVRWLGDGFDTPDVCRIAVMERYGQQRVPALGLLHNSGLSKGALAATVSHDSHNIVV
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEEE
IGHHPAEMALAVNQLIDDGGGLCVVADGQVVVHLPLPIAGLMSSRSAAEIADIIDALKQA
EECCCHHHHHHHHHHHCCCCCEEEEECCEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHH
CRNCGMTLNEPFIQMAFLSLPVIPSLKLTSLGLYDVDHFRFTEVRIPEESA
HHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCEECCCEEEEEEECCCCCC
>Mature Secondary Structure
MEDIHHKHTQSVSRSDMLRLLAVSRGDQPADLIIDNVFLLDLINGGTLPGPILISGDSIA
CCCCCHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEECCCCCCCCCEEEECCCCC
GVGPAYAGTAALERIDAGGAIAVPGFIDAHLHIESSMMTPIAFESVTLPLGVTTIVCDPH
CCCCHHHHHHHHHHHCCCCEEECCCEEEEEEEECCCCCCCEEECEEEECCCEEEEEECHH
EIVNVMGEKGLTWFLRCAEGAQQNQFIQISSCVPALAGTDINGAEFPLTAMLPYREHPHV
HHHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCHHCCCCCCCCCCCEEEECCCCCCCCE
LGLAEMMNFPGVIAGDEPTLDKLDAFRHLTLDGHSPMLSGKALNAYLAAGVENCHETLAL
EEHHHHHCCCCEEECCCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EEGREKLALGMALMIREGSAARNLDTLAPLISEFNSPQCMLCTDDRNPWEIAHEGHIDAL
HHCHHHHHHCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCHHHH
IRRLIQRHHIAPHVAYRVASWSAARHFGLKRLGLIAPGKKADIVLLDNLEQVAIRQVFAG
HHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHCEECCCCCCCEEEECCHHHHHHHHHHCC
GKAIDAQQLLRSAAMRQLASCPPQHNTLRRAPLSAEDLTLPLTQDADYRAIQLIPNELIT
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCEEEECCCCCCCEEEEECCHHHCC
PARTVRWLGDGFDTPDVCRIAVMERYGQQRVPALGLLHNSGLSKGALAATVSHDSHNIVV
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEECCCCEEEE
IGHHPAEMALAVNQLIDDGGGLCVVADGQVVVHLPLPIAGLMSSRSAAEIADIIDALKQA
EECCCHHHHHHHHHHHCCCCCEEEEECCEEEEEECCCHHHHHCCCCHHHHHHHHHHHHHH
CRNCGMTLNEPFIQMAFLSLPVIPSLKLTSLGLYDVDHFRFTEVRIPEESA
HHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCEECCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA