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The map label for this gene is argE

Identifier: 238921688

GI number: 238921688

Start: 3729307

End: 3730458

Strand: Direct

Name: argE

Synonym: NT01EI_3849

Alternate gene names: 238921688

Gene position: 3729307-3730458 (Clockwise)

Preceding gene: 238921682

Following gene: 238921689

Centisome position: 97.82

GC content: 57.47

Gene sequence:

>1152_bases
ATGAATACACAATTACCCTCATTTATCGCGTTGTACCGTGCGCTGATCGCAACCCCCTCCATCAGCGCCAACGACGGTGC
ACTGGACCAGAGTAATGAACGGTTAATCACGCTGCTGGCAGGATGGCTTAGCGATCTCGGATTGCGAGTTGAGATGCAGC
CAGTCCCTAACACACGGAATAAATTCAATTTACTAGCAAACTATGGTGAGGGGGCCGGTGGACTGATGCTGGCAGGGCAT
ACCGATACGGTTCCCTTTGACGAGGGGCGCTGGACCCGGGATCCCTTCACACTTAGCGAACAGGATAATCGCCTGTACGG
TCTTGGAACCGCAGACATGAAAGGATTATTCGCTTTTATTATCGATACCCTGCGCGATATCGAACTGCATAAACTGAATA
AACCGCTCTACATTTTGGCGACGGCTGATGAGGAGACCTCAATGGCGGGTGCGCGCTATTTTGCCGCCAGCACCGCGCTG
CGCCCCGACTGCTGCATCATCGGCGAGCCCACCTCCCTTAAGCCTATCCGGGCCCATAAAGGCCATCTCTCCGAGGCCAT
CCGCATCACCGGTCAGTCAGGACACTCCAGCGATCCGGCACGCGGCGTCAACGCGATCGAGATCATGCACAATGCCATCG
GTCACCTGCTCACCCTGCGCAATACGCTACAACAGCGCTACCACAATCCGGCCTTTAATATCCCTTATCCCACCATGAAC
CTGGGGCATATCCACGGTGGCGATGCGGCCAACCGCATCTGTGCCTGCTGCGAGTTACACCTGGATATGCGTCCGCTGCC
GGGAATGACGCTGAACGATCTCAACGAGCTACTGAACCAGGCGCTGACGCCCATCGCGGCGCAGTGGTCGGGACGTCTGC
GTATTGAGCACCTGCATCCGCCGATCCCCGGCTATGAATGCCCGCGCCACGCGCCGCTGGTGCAGGCAATAGAACAGCTA
TTGGGGGAGCGGGCAGAAGCCGTCAACTACTGTACCGAGGCGCCGTTCCTGCAAGAGGTTTGCCCAACGCTGGTACTCGG
CCCGGGATCCATTGAGCAGGCACATCAGCCGGATGAGTACCTGTCCACCGACTTTATTGTGCCGACGCGCACTCTGCTGA
CGCAGCTAATCCACCATTTCTGTCAGCGCTGA

Upstream 100 bases:

>100_bases
TCGGGCGTCCCTGTCTGTTCCTTTCGATGATGTTTTAATGTATTTTTATTCATAATTATTGCATGAATATTGATACTATC
CAAACCAGAGACTGTCAACC

Downstream 100 bases:

>100_bases
TCGCGGTAGGCACTGCCTTGGGCAAACGATGGCGCGACGGCGTTTGCAATGTAACTGTTATCAGTTAGACCTCTCCAGGT
CATTGCGTAATTAAATTTCA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MNTQLPSFIALYRALIATPSISANDGALDQSNERLITLLAGWLSDLGLRVEMQPVPNTRNKFNLLANYGEGAGGLMLAGH
TDTVPFDEGRWTRDPFTLSEQDNRLYGLGTADMKGLFAFIIDTLRDIELHKLNKPLYILATADEETSMAGARYFAASTAL
RPDCCIIGEPTSLKPIRAHKGHLSEAIRITGQSGHSSDPARGVNAIEIMHNAIGHLLTLRNTLQQRYHNPAFNIPYPTMN
LGHIHGGDAANRICACCELHLDMRPLPGMTLNDLNELLNQALTPIAAQWSGRLRIEHLHPPIPGYECPRHAPLVQAIEQL
LGERAEAVNYCTEAPFLQEVCPTLVLGPGSIEQAHQPDEYLSTDFIVPTRTLLTQLIHHFCQR

Sequences:

>Translated_383_residues
MNTQLPSFIALYRALIATPSISANDGALDQSNERLITLLAGWLSDLGLRVEMQPVPNTRNKFNLLANYGEGAGGLMLAGH
TDTVPFDEGRWTRDPFTLSEQDNRLYGLGTADMKGLFAFIIDTLRDIELHKLNKPLYILATADEETSMAGARYFAASTAL
RPDCCIIGEPTSLKPIRAHKGHLSEAIRITGQSGHSSDPARGVNAIEIMHNAIGHLLTLRNTLQQRYHNPAFNIPYPTMN
LGHIHGGDAANRICACCELHLDMRPLPGMTLNDLNELLNQALTPIAAQWSGRLRIEHLHPPIPGYECPRHAPLVQAIEQL
LGERAEAVNYCTEAPFLQEVCPTLVLGPGSIEQAHQPDEYLSTDFIVPTRTLLTQLIHHFCQR
>Mature_383_residues
MNTQLPSFIALYRALIATPSISANDGALDQSNERLITLLAGWLSDLGLRVEMQPVPNTRNKFNLLANYGEGAGGLMLAGH
TDTVPFDEGRWTRDPFTLSEQDNRLYGLGTADMKGLFAFIIDTLRDIELHKLNKPLYILATADEETSMAGARYFAASTAL
RPDCCIIGEPTSLKPIRAHKGHLSEAIRITGQSGHSSDPARGVNAIEIMHNAIGHLLTLRNTLQQRYHNPAFNIPYPTMN
LGHIHGGDAANRICACCELHLDMRPLPGMTLNDLNELLNQALTPIAAQWSGRLRIEHLHPPIPGYECPRHAPLVQAIEQL
LGERAEAVNYCTEAPFLQEVCPTLVLGPGSIEQAHQPDEYLSTDFIVPTRTLLTQLIHHFCQR

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily

Homologues:

Organism=Escherichia coli, GI1790395, Length=381, Percent_Identity=75.0656167979003, Blast_Score=621, Evalue=1e-179,
Organism=Escherichia coli, GI1788816, Length=257, Percent_Identity=30.3501945525292, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789236, Length=372, Percent_Identity=24.1935483870968, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551016, Length=352, Percent_Identity=25.8522727272727, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGE_EDWI9 (C5BC62)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002935203.1
- ProteinModelPortal:   C5BC62
- GeneID:   7959890
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3849
- OMA:   RICGQCA
- ProtClustDB:   PRK05111
- GO:   GO:0005737
- GO:   GO:0006508
- HAMAP:   MF_01108
- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- TIGRFAMs:   TIGR01892

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20; SSF55031 Peptidase_M20_dimer

EC number: =3.5.1.16

Molecular weight: Translated: 42280; Mature: 42280

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00758 ARGE_DAPE_CPG2_1; PS00759 ARGE_DAPE_CPG2_2

Important sites: ACT_SITE 82-82 ACT_SITE 144-144

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQLPSFIALYRALIATPSISANDGALDQSNERLITLLAGWLSDLGLRVEMQPVPNTRN
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCC
KFNLLANYGEGAGGLMLAGHTDTVPFDEGRWTRDPFTLSEQDNRLYGLGTADMKGLFAFI
CEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHH
IDTLRDIELHKLNKPLYILATADEETSMAGARYFAASTALRPDCCIIGEPTSLKPIRAHK
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHH
GHLSEAIRITGQSGHSSDPARGVNAIEIMHNAIGHLLTLRNTLQQRYHNPAFNIPYPTMN
HHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LGHIHGGDAANRICACCELHLDMRPLPGMTLNDLNELLNQALTPIAAQWSGRLRIEHLHP
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHCCCCEEEEECCC
PIPGYECPRHAPLVQAIEQLLGERAEAVNYCTEAPFLQEVCPTLVLGPGSIEQAHQPDEY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHEEECCCCCCCCCCCHHH
LSTDFIVPTRTLLTQLIHHFCQR
HCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTQLPSFIALYRALIATPSISANDGALDQSNERLITLLAGWLSDLGLRVEMQPVPNTRN
CCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCC
KFNLLANYGEGAGGLMLAGHTDTVPFDEGRWTRDPFTLSEQDNRLYGLGTADMKGLFAFI
CEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHH
IDTLRDIELHKLNKPLYILATADEETSMAGARYFAASTALRPDCCIIGEPTSLKPIRAHK
HHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHH
GHLSEAIRITGQSGHSSDPARGVNAIEIMHNAIGHLLTLRNTLQQRYHNPAFNIPYPTMN
HHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
LGHIHGGDAANRICACCELHLDMRPLPGMTLNDLNELLNQALTPIAAQWSGRLRIEHLHP
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCHHHHHCCCCEEEEECCC
PIPGYECPRHAPLVQAIEQLLGERAEAVNYCTEAPFLQEVCPTLVLGPGSIEQAHQPDEY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHEEECCCCCCCCCCCHHH
LSTDFIVPTRTLLTQLIHHFCQR
HCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA