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The map label for this gene is tsr [H]

Identifier: 238921617

GI number: 238921617

Start: 3656553

End: 3658109

Strand: Reverse

Name: tsr [H]

Synonym: NT01EI_3772

Alternate gene names: 238921617

Gene position: 3658109-3656553 (Counterclockwise)

Preceding gene: 238921618

Following gene: 238921616

Centisome position: 95.96

GC content: 58.45

Gene sequence:

>1557_bases
ATGAATCAACGAATTACAGTTCGTGGCGGACTGCTTGTCATCATCTTTGCCTATACCTTATTGCTATTCTTTATCAGCAG
CATGGGCATTTATTTCTTAGGCCAGAGTAATCATTCGCTGGCGGTAGTAAACCAGATACAGGCAAGTGAGCTGGGGCCGC
TTTCTACCGGGTTCAGTGCGACGCTGCGCGCCCGCTCTGCAGCAGCCATTGCAGCCCGTCAGCTGACGCTGGAACATATC
GCTGATGCTGATAAAAGTCGCCGTACAGTGGAGACGTTACTGGCTGAGTCCAATGAAATCATGGCACAGTTCTCCGCGCT
GAAAAAAGTTACTGTGGAAGGACAGCGTTTGAGTATCCGCCTGGAACAGAGCTATAACGCCTATATTCAGGATGGCCTGC
AGCCGATGGTACAGGCATTGGCTGCGCGGAATCTGGATACCTACTATTCCCTGCTGGAGAATCAGGTTAACAACCATTCA
ACGGAGTACGACCGCGATCTGCGCGGATTTCGGAAGTTTGCTGATACGCTGGGGCACCAGGCGCTGGAAAAGGCGCAGCG
GGACTACCAGCGAGCCATGATCCTGATCATCTCTGCCTGCGTACTGTTGCTGGCGGTCGGGGGCTTCTGCTGGTACGCCC
TGCGCGGCATCATTCTGCGGCCGTTGGCTCAGCTGGATGAGCAGGTGGAGCATATCGCCGCCGGGGACTTGACCTGTCAG
CTGGCGCTGAGCGGTCGCTCGGAGATAGCCCACCTGGGTCGACAGCTGGCACAGATGCAGCAGGCGTTGGCCGGGACGGT
ACGCCGGGTACGTGACGCCAGCGAACAGGTTGATGTCGGTGCCCGTGAGTTGCGCGCCGGTAACCGCGATCTGTCGCAGC
GTACCGAAGAGCTGGCAGCGTCGTTGGAGGAGACAGCGGCCAGCATGGAGCAGTTGACGGCGACGGTGCGTCAGAACGCG
GCCAATGCGGAGCAGGCTAATTTGCTGGCGAGCGGCGTTTCCGACAGCGCGAATCAGGGCGCGGGTATCGTTAATGAGGC
GATCGTCGGCATGCGCAGCATTTCTCATAGTTCACAGAAGATCGCCGATATTATCAGCGTAATCGACGGGATTGCCTTCC
AAACCAATATTCTGGCGCTCAATGCGGCGGTAGAAGCGGCGCGTGCCGGTGAGCAGGGGCGTGGTTTTGCCGTGGTGGCC
GGTGAGGTTCGCAACCTGGCACAGCGCAGCGCCCAGTCAGCGAAAGAGATTAAGCTGCTGATCGAAGATTCGGTGCGTCA
GGTGAGCGACGGCGAGCGACGCGTCAGCGCGGCGGCGGAAACCATGGCAAAAATTTCCAGCGAGGTGGTACGCGTGACGG
CGCTGATGGCGGAGATCTCCGGTGCCTCTCAGGAGCAAACCCGCGGTATCGAGCAGGTAAACCAGGCTGTCGCTCAGATG
GATCAGGTGGCACAGCAAAACGCGGCGCTGGTAGAAGAATCCACCGCGGCCACGGCGTCGCTGGAGGCACAAAGCGAGCA
GCTGATACAGAGCATGGAGATCTTTAAGCTCGCCTGA

Upstream 100 bases:

>100_bases
TTTCGTCCCTGTGGCCGATAAATCGAACGCTGACTTAAACAGTAAACCTGGCCAAGGGATGATCCCATCATGGCGCAGTA
TTATTTACAGGGAATAATTA

Downstream 100 bases:

>100_bases
TCTGCGGGGGCGGTGAGGCGCCAGGGGCCCGCCATCACCGCCTACGATCGCCGCCTCGGTGCGCGCCGCAAGGTTGCTTG
CCAGCCCTGTGAGGCGTGCG

Product: methyl-accepting chemotaxis protein I

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MNQRITVRGGLLVIIFAYTLLLFFISSMGIYFLGQSNHSLAVVNQIQASELGPLSTGFSATLRARSAAAIAARQLTLEHI
ADADKSRRTVETLLAESNEIMAQFSALKKVTVEGQRLSIRLEQSYNAYIQDGLQPMVQALAARNLDTYYSLLENQVNNHS
TEYDRDLRGFRKFADTLGHQALEKAQRDYQRAMILIISACVLLLAVGGFCWYALRGIILRPLAQLDEQVEHIAAGDLTCQ
LALSGRSEIAHLGRQLAQMQQALAGTVRRVRDASEQVDVGARELRAGNRDLSQRTEELAASLEETAASMEQLTATVRQNA
ANAEQANLLASGVSDSANQGAGIVNEAIVGMRSISHSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQSAKEIKLLIEDSVRQVSDGERRVSAAAETMAKISSEVVRVTALMAEISGASQEQTRGIEQVNQAVAQM
DQVAQQNAALVEESTAATASLEAQSEQLIQSMEIFKLA

Sequences:

>Translated_518_residues
MNQRITVRGGLLVIIFAYTLLLFFISSMGIYFLGQSNHSLAVVNQIQASELGPLSTGFSATLRARSAAAIAARQLTLEHI
ADADKSRRTVETLLAESNEIMAQFSALKKVTVEGQRLSIRLEQSYNAYIQDGLQPMVQALAARNLDTYYSLLENQVNNHS
TEYDRDLRGFRKFADTLGHQALEKAQRDYQRAMILIISACVLLLAVGGFCWYALRGIILRPLAQLDEQVEHIAAGDLTCQ
LALSGRSEIAHLGRQLAQMQQALAGTVRRVRDASEQVDVGARELRAGNRDLSQRTEELAASLEETAASMEQLTATVRQNA
ANAEQANLLASGVSDSANQGAGIVNEAIVGMRSISHSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQSAKEIKLLIEDSVRQVSDGERRVSAAAETMAKISSEVVRVTALMAEISGASQEQTRGIEQVNQAVAQM
DQVAQQNAALVEESTAATASLEAQSEQLIQSMEIFKLA
>Mature_518_residues
MNQRITVRGGLLVIIFAYTLLLFFISSMGIYFLGQSNHSLAVVNQIQASELGPLSTGFSATLRARSAAAIAARQLTLEHI
ADADKSRRTVETLLAESNEIMAQFSALKKVTVEGQRLSIRLEQSYNAYIQDGLQPMVQALAARNLDTYYSLLENQVNNHS
TEYDRDLRGFRKFADTLGHQALEKAQRDYQRAMILIISACVLLLAVGGFCWYALRGIILRPLAQLDEQVEHIAAGDLTCQ
LALSGRSEIAHLGRQLAQMQQALAGTVRRVRDASEQVDVGARELRAGNRDLSQRTEELAASLEETAASMEQLTATVRQNA
ANAEQANLLASGVSDSANQGAGIVNEAIVGMRSISHSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQSAKEIKLLIEDSVRQVSDGERRVSAAAETMAKISSEVVRVTALMAEISGASQEQTRGIEQVNQAVAQM
DQVAQQNAALVEESTAATASLEAQSEQLIQSMEIFKLA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=530, Percent_Identity=42.6415094339623, Blast_Score=335, Evalue=5e-93,
Organism=Escherichia coli, GI1788195, Length=529, Percent_Identity=42.1550094517958, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI1788194, Length=521, Percent_Identity=43.3781190019194, Blast_Score=329, Evalue=3e-91,
Organism=Escherichia coli, GI1787690, Length=512, Percent_Identity=42.3828125, Blast_Score=326, Evalue=3e-90,
Organism=Escherichia coli, GI1789453, Length=328, Percent_Identity=39.3292682926829, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55955; Mature: 55955

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRITVRGGLLVIIFAYTLLLFFISSMGIYFLGQSNHSLAVVNQIQASELGPLSTGFSA
CCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCHHH
TLRARSAAAIAARQLTLEHIADADKSRRTVETLLAESNEIMAQFSALKKVTVEGQRLSIR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEE
LEQSYNAYIQDGLQPMVQALAARNLDTYYSLLENQVNNHSTEYDRDLRGFRKFADTLGHQ
EECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALEKAQRDYQRAMILIISACVLLLAVGGFCWYALRGIILRPLAQLDEQVEHIAAGDLTCQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LALSGRSEIAHLGRQLAQMQQALAGTVRRVRDASEQVDVGARELRAGNRDLSQRTEELAA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHH
SLEETAASMEQLTATVRQNAANAEQANLLASGVSDSANQGAGIVNEAIVGMRSISHSSQK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
IADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQSAKEIKLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
IEDSVRQVSDGERRVSAAAETMAKISSEVVRVTALMAEISGASQEQTRGIEQVNQAVAQM
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
DQVAQQNAALVEESTAATASLEAQSEQLIQSMEIFKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQRITVRGGLLVIIFAYTLLLFFISSMGIYFLGQSNHSLAVVNQIQASELGPLSTGFSA
CCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCHHH
TLRARSAAAIAARQLTLEHIADADKSRRTVETLLAESNEIMAQFSALKKVTVEGQRLSIR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEE
LEQSYNAYIQDGLQPMVQALAARNLDTYYSLLENQVNNHSTEYDRDLRGFRKFADTLGHQ
EECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALEKAQRDYQRAMILIISACVLLLAVGGFCWYALRGIILRPLAQLDEQVEHIAAGDLTCQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
LALSGRSEIAHLGRQLAQMQQALAGTVRRVRDASEQVDVGARELRAGNRDLSQRTEELAA
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHH
SLEETAASMEQLTATVRQNAANAEQANLLASGVSDSANQGAGIVNEAIVGMRSISHSSQK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCHHHH
IADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQSAKEIKLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
IEDSVRQVSDGERRVSAAAETMAKISSEVVRVTALMAEISGASQEQTRGIEQVNQAVAQM
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
DQVAQQNAALVEESTAATASLEAQSEQLIQSMEIFKLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]