Click here to switch to the map view.

The map label for this gene is dtpB [H]

Identifier: 238921578

GI number: 238921578

Start: 3616325

End: 3617800

Strand: Direct

Name: dtpB [H]

Synonym: NT01EI_3731

Alternate gene names: 238921578

Gene position: 3616325-3617800 (Clockwise)

Preceding gene: 238921576

Following gene: 238921579

Centisome position: 94.86

GC content: 60.09

Gene sequence:

>1476_bases
ATGAACAACACCGCGCCCGGTTTACTCCACCAACCCAAGCCCTTCTTCATGATCTTCTTCGTTGAGCTGTGGGAGCGCTT
CGGTTATTACGGCGTACAGGGCATTCTGGCCGTCTTTTTCGTCAAGCAACTGGGCTTCTCACAGGAGCAGGCCTTCATCA
CTTTCGGTGCCTTTGCCGCGCTGGTCTACGGACTGATCTCTATCGGCGGCTACGTCGGCGACCATCTGCTGGGCACCAAG
CGCACCATGGTGCTCGGCGCCATCGTGCTGGCGCTGGGCTACTTCATGACCGGTATCTCGCTGCTGAAACCAGAGATGAT
CTTCATCGCTCTGGGGACCATCGCCGTCGGCAATGGTCTGTTCAAGGCGAACCCGGCCAGCCTGCTCTCCAAATGCTACC
CGCAGAAGGATCCTCGTCTGGATGGCGCCTTCACCCTGTTTTACATGTCCATCAACGTCGGATCGCTGCTCTCCCTCTCC
CTGGCACCGATCATCGCCGAGCGCTTCGGCTATGCGGTGACCTATAACCTGTGCGGCCTGGGACTGATCATCGCCCTGCT
GGTCTACTTTGCCTGCCGCGGCATGGTACGCAACATCGGCTCAGCACCGGATCATCAGCCGCTGAACTATGGCAAGCTGC
TGCTGGTACTGGCCGGGGCCGTGGTCATGATCGCGATTTGCGCCTGGCTGATGCACAACGTCGGCGTCGCCAACATCGTG
CTGATCGCCCTCTCCGCAGTGGTGCTGTACTTCTTCTTCCGCGAGGCCTTTAAGCAGGATAAAACCGGGCGCAACCGGAT
GTTCGTCGCGTTCATCCTGATGGTCGAAGCCGTCCTGTTCTACATTCTCTATGCGCAGATGCCGACCTCGCTTAACTTCT
TCGCCATCAATAACGTCCGCCATGAGCTGCTCGGCTTCGCCATTAACCCGGTCAGCTTCCAGGCGCTCAACCCGTTCTGG
GTCGTGGTGGCCAGCCCGGTCCTGGCCTCGATCTACACCCGCCTGGGCAGCCGCGGCCGCGACATGACCATGCCGACCAA
ATTTACCCTGGGAATGCTGCTGTGCTCTCTGGGCTTCCTCACCGCCGCTGCCGCGGGCATGTGGTTTGCCGACACTCAGG
GGTTAACCTCTCCCTGGTTTGTGGTGCTGGTCTACCTGTTCCAGAGCCTCGGGGAGCTGATGATCAGCGCGCTTGGGCTG
GCAATGGTCGCCGCGCTGGTCCCCCAGTATCTGATGGGCTTTATTCTGGGGATGTGGTTCCTGACCCAGGCCGCCGCCTT
CCTGCTCGGTGGCTACGTCGCGACCCTCACCGCGGTCCCGGCGGGGATCCACGATCCGCTGCAGACCCTGCCCATCTATA
CCGGCGTCTTCGGTAAGATCGGTATCGCTACGCTGATCGTCACGCTGGTGATGGCAGCAATGGTACCCTGGCTTAACCGG
ATGATGAACACACCGATCGATGGCCAAAAAGCCTAA

Upstream 100 bases:

>100_bases
CCTATCTGCTTATAAAATGGCATTCTGTTTCATTAGATCGTGGGGTGACAGGCCCCGCCGACCCTTTTCGCGACATAACA
ATAATCTGAGATCAACCACA

Downstream 100 bases:

>100_bases
TTATTCTCTTCTCAATAAAGCCCTGACAGCACAGGGCTTTGTTCTTTTTTTCTCCAGCTAAAACTCCTTGCGCTGCCCGT
GTGAAGCGATGCTATAGTCC

Product: inner membrane transporter YhiP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MNNTAPGLLHQPKPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGTK
RTMVLGAIVLALGYFMTGISLLKPEMIFIALGTIAVGNGLFKANPASLLSKCYPQKDPRLDGAFTLFYMSINVGSLLSLS
LAPIIAERFGYAVTYNLCGLGLIIALLVYFACRGMVRNIGSAPDHQPLNYGKLLLVLAGAVVMIAICAWLMHNVGVANIV
LIALSAVVLYFFFREAFKQDKTGRNRMFVAFILMVEAVLFYILYAQMPTSLNFFAINNVRHELLGFAINPVSFQALNPFW
VVVASPVLASIYTRLGSRGRDMTMPTKFTLGMLLCSLGFLTAAAAGMWFADTQGLTSPWFVVLVYLFQSLGELMISALGL
AMVAALVPQYLMGFILGMWFLTQAAAFLLGGYVATLTAVPAGIHDPLQTLPIYTGVFGKIGIATLIVTLVMAAMVPWLNR
MMNTPIDGQKA

Sequences:

>Translated_491_residues
MNNTAPGLLHQPKPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGTK
RTMVLGAIVLALGYFMTGISLLKPEMIFIALGTIAVGNGLFKANPASLLSKCYPQKDPRLDGAFTLFYMSINVGSLLSLS
LAPIIAERFGYAVTYNLCGLGLIIALLVYFACRGMVRNIGSAPDHQPLNYGKLLLVLAGAVVMIAICAWLMHNVGVANIV
LIALSAVVLYFFFREAFKQDKTGRNRMFVAFILMVEAVLFYILYAQMPTSLNFFAINNVRHELLGFAINPVSFQALNPFW
VVVASPVLASIYTRLGSRGRDMTMPTKFTLGMLLCSLGFLTAAAAGMWFADTQGLTSPWFVVLVYLFQSLGELMISALGL
AMVAALVPQYLMGFILGMWFLTQAAAFLLGGYVATLTAVPAGIHDPLQTLPIYTGVFGKIGIATLIVTLVMAAMVPWLNR
MMNTPIDGQKA
>Mature_491_residues
MNNTAPGLLHQPKPFFMIFFVELWERFGYYGVQGILAVFFVKQLGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGTK
RTMVLGAIVLALGYFMTGISLLKPEMIFIALGTIAVGNGLFKANPASLLSKCYPQKDPRLDGAFTLFYMSINVGSLLSLS
LAPIIAERFGYAVTYNLCGLGLIIALLVYFACRGMVRNIGSAPDHQPLNYGKLLLVLAGAVVMIAICAWLMHNVGVANIV
LIALSAVVLYFFFREAFKQDKTGRNRMFVAFILMVEAVLFYILYAQMPTSLNFFAINNVRHELLGFAINPVSFQALNPFW
VVVASPVLASIYTRLGSRGRDMTMPTKFTLGMLLCSLGFLTAAAAGMWFADTQGLTSPWFVVLVYLFQSLGELMISALGL
AMVAALVPQYLMGFILGMWFLTQAAAFLLGGYVATLTAVPAGIHDPLQTLPIYTGVFGKIGIATLIVTLVMAAMVPWLNR
MMNTPIDGQKA

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=360, Percent_Identity=25.5555555555556, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4827008, Length=389, Percent_Identity=23.3933161953728, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1789911, Length=486, Percent_Identity=82.0987654320988, Blast_Score=823, Evalue=0.0,
Organism=Escherichia coli, GI1787922, Length=472, Percent_Identity=51.6949152542373, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1786927, Length=446, Percent_Identity=27.5784753363229, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI1790572, Length=433, Percent_Identity=27.7136258660508, Blast_Score=147, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17541704, Length=371, Percent_Identity=25.6064690026954, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17569141, Length=385, Percent_Identity=24.9350649350649, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571098, Length=202, Percent_Identity=27.2277227722772, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28571102, Length=205, Percent_Identity=27.3170731707317, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571100, Length=205, Percent_Identity=27.3170731707317, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24639585, Length=331, Percent_Identity=24.773413897281, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639583, Length=331, Percent_Identity=24.773413897281, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24639581, Length=331, Percent_Identity=24.773413897281, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53506; Mature: 53506

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCCC
>Mature Secondary Structure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HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA