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The map label for this gene is pheC [H]

Identifier: 238921538

GI number: 238921538

Start: 3580377

End: 3581147

Strand: Direct

Name: pheC [H]

Synonym: NT01EI_3690

Alternate gene names: 238921538

Gene position: 3580377-3581147 (Clockwise)

Preceding gene: 238921537

Following gene: 238921545

Centisome position: 93.92

GC content: 43.58

Gene sequence:

>771_bases
ATGAAAAAAATACATTTTTGGTTGACGATTCTGTTATCACTTTCAGGTATTCATTCCGCAACGGCAAAAGGATGGCAGGA
TATTAAACAGAGTGGAGAGTTACGTGTGGGAGTACCTGGTGACTATGCTCCTCTTGCATTTCACGACAAGCAAGGGCATC
TGGTTGGTTTTGATATTGATATGGCGCATTCACTGGGCCAGGCGTTGCACCTCAATATCCGTTTTGTGCTGAGTAGCTGG
CCTACGTTATCAGCGGATCTGGCTGCTGACAAGTTTGATATTGCGATGGGAGGGGTCACTGAAACCCCCGATAGAAGAGA
AAAGTTCGCACTTTCCTCTCCTGTTCTTAAAAATGGGAAAATAGCACTGACACAGTGCAACAGGGTTAATGACTTCAAAT
CCCTTGAGGATATAGACCATACAGAAGTCCGGGTTGTTGTTAATCCGGGAGGCACAAATCAGGACTATGTTGACATACAC
ATCAGGCATGCGAAGGTTATTCGTGAAAGAGACAATACCGCCAGTTTGCAGCGGATCCGTGAGCGCAGCGCTGATATCAT
GTTTACCGATTTACTCGAGGGTAACTATTACCAGAACAATGAGCCTGGCATCTTCTGTGTATCAATTATGAACATTTTAC
CAGGAACAGTAAGCAATAAAGTTTATATGATGGCGAAGGATAATAAGTATCTTCTTAAAACTATAGACAAGTGGCTATCT
GACGGAAACAAAAGCAGGCTTTCCAGAAAGTGGCAGATATCTACAGAGTAG

Upstream 100 bases:

>100_bases
CCGTCCGACGGCCTATAGGACACTCTCCCGTGGCAATGGCAGGAAGGATATTTTATTCGCAGCCATAGTTTTAAACATTG
ACTAAACATCGAGAGAGAAA

Downstream 100 bases:

>100_bases
CAACACGCTTTTACTTATAAAATGACGAATATGAAAAGTTTTCAAGGCTTCTTTCGTCGAGCTCCTATATCATGGATACT
TCCGTAGTGTTGGTCAGCCT

Product: ABC transporter, perplasmic amino acid binding protein

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKKIHFWLTILLSLSGIHSATAKGWQDIKQSGELRVGVPGDYAPLAFHDKQGHLVGFDIDMAHSLGQALHLNIRFVLSSW
PTLSADLAADKFDIAMGGVTETPDRREKFALSSPVLKNGKIALTQCNRVNDFKSLEDIDHTEVRVVVNPGGTNQDYVDIH
IRHAKVIRERDNTASLQRIRERSADIMFTDLLEGNYYQNNEPGIFCVSIMNILPGTVSNKVYMMAKDNKYLLKTIDKWLS
DGNKSRLSRKWQISTE

Sequences:

>Translated_256_residues
MKKIHFWLTILLSLSGIHSATAKGWQDIKQSGELRVGVPGDYAPLAFHDKQGHLVGFDIDMAHSLGQALHLNIRFVLSSW
PTLSADLAADKFDIAMGGVTETPDRREKFALSSPVLKNGKIALTQCNRVNDFKSLEDIDHTEVRVVVNPGGTNQDYVDIH
IRHAKVIRERDNTASLQRIRERSADIMFTDLLEGNYYQNNEPGIFCVSIMNILPGTVSNKVYMMAKDNKYLLKTIDKWLS
DGNKSRLSRKWQISTE
>Mature_256_residues
MKKIHFWLTILLSLSGIHSATAKGWQDIKQSGELRVGVPGDYAPLAFHDKQGHLVGFDIDMAHSLGQALHLNIRFVLSSW
PTLSADLAADKFDIAMGGVTETPDRREKFALSSPVLKNGKIALTQCNRVNDFKSLEDIDHTEVRVVVNPGGTNQDYVDIH
IRHAKVIRERDNTASLQRIRERSADIMFTDLLEGNYYQNNEPGIFCVSIMNILPGTVSNKVYMMAKDNKYLLKTIDKWLS
DGNKSRLSRKWQISTE

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=244, Percent_Identity=23.3606557377049, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787085, Length=224, Percent_Identity=20.9821428571429, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 28867; Mature: 28867

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIHFWLTILLSLSGIHSATAKGWQDIKQSGELRVGVPGDYAPLAFHDKQGHLVGFDID
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEECCCCCEEEEEHH
MAHSLGQALHLNIRFVLSSWPTLSADLAADKFDIAMGGVTETPDRREKFALSSPVLKNGK
HHHHCCCEEEEEEEEEEECCCCCCHHHCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCC
IALTQCNRVNDFKSLEDIDHTEVRVVVNPGGTNQDYVDIHIRHAKVIRERDNTASLQRIR
EEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEHHHHHHCCCHHHHHHHH
ERSADIMFTDLLEGNYYQNNEPGIFCVSIMNILPGTVSNKVYMMAKDNKYLLKTIDKWLS
HHCCCEEEEEECCCCCEECCCCCEEEEEHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHC
DGNKSRLSRKWQISTE
CCCHHHCCEEEEECCC
>Mature Secondary Structure
MKKIHFWLTILLSLSGIHSATAKGWQDIKQSGELRVGVPGDYAPLAFHDKQGHLVGFDID
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEECCCCCCCCEEEECCCCCEEEEEHH
MAHSLGQALHLNIRFVLSSWPTLSADLAADKFDIAMGGVTETPDRREKFALSSPVLKNGK
HHHHCCCEEEEEEEEEEECCCCCCHHHCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCC
IALTQCNRVNDFKSLEDIDHTEVRVVVNPGGTNQDYVDIHIRHAKVIRERDNTASLQRIR
EEEEECCCCCCHHHHHCCCCCEEEEEECCCCCCCCEEEEEEEEHHHHHHCCCHHHHHHHH
ERSADIMFTDLLEGNYYQNNEPGIFCVSIMNILPGTVSNKVYMMAKDNKYLLKTIDKWLS
HHCCCEEEEEECCCCCEECCCCCEEEEEHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHC
DGNKSRLSRKWQISTE
CCCHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]