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The map label for this gene is yheS [H]

Identifier: 238921458

GI number: 238921458

Start: 3494790

End: 3496676

Strand: Direct

Name: yheS [H]

Synonym: NT01EI_3610

Alternate gene names: 238921458

Gene position: 3494790-3496676 (Clockwise)

Preceding gene: 238921453

Following gene: 238921460

Centisome position: 91.67

GC content: 62.64

Gene sequence:

>1887_bases
GTGCTGCTGGACAATGCCTCGGCAACGATCAACCCCGGCCAAAAGGTGGGCCTGGTCGGCAAAAATGGCTGTGGGAAATC
AACGCTGCTGGCGCTGTTGAAAAATGAGCTGAGCGCCGACGGCGGTAATCTGACCCTGCCCGGCAACTGGGCCATGGCCT
GGGTTAACCAGGAGACGCCGGCGCTGGAAACGCCGGCGCTGGAATATGTGCTCGACGGCGATCGCGAGTTCCGCCAGCTG
GAGCAGCAGCTCGATGATGCCAACCAGCGTAACGATGGCAACACGATCGCGCTGATCCACGGCAAGCTGGACGCCATTGC
CGCCTGGACCATTCGCGCCCGCGCCTCCAGTCTGCTGCACGGCCTCGGCTTCAGCCAGGAACAGCTCATGCAGCCGGTGA
GATCCTTCTCCGGCGGCTGGCGCATGCGCCTGAACCTGGCACAGGCGCTGCTGTGCCGCTCCGATCTGCTGCTGCTCGAC
GAACCGACCAACCACCTGGATCTGGACGCGGTGATCTGGCTGGAGCGCTGGCTGAAAAGCTATCCGGGCACACTGATCCT
GATTTCACACGACCGTGACTTCCTCGATCCTATCGTGGACAAAATTGTACATATCGAACAGCAGCAGCTGTTTGAATACA
GCGGAAACTACTCCTCTTTCGAACTGCAGCGCGCCGGGAAACTGGCGCAGCAGCAGGCGATGTATCAGAGCCAGCAGCAG
CGTATCGCCCATCTGCAAAGCTATATCGACCGCTTCAAGGCCAAGGCCAGTAAGGCCAAGCAGGCGCAGAGCCGGGTAAA
AATGCTGGAACGCATGGAGCGCATCGCGCCGGCCCACGTCGATAACCCGTTCCACTTCAGCTTCCGCGCGCCGGAAAGCC
TGCCGACGCCGCTGCTGCGTATGGAGCACGTCAGCGCCGGCTACGGCGAGCGCACCGTACTCGCCTCGATTAAGCTCAAC
CTGGTACCCGGTTCGCGCATCGGTCTGCTGGGACGTAACGGCGCCGGTAAGTCCACCCTGATCAAGCTGCTGGCCGGCGA
GCTAGCGCCGCAGCAGGGGGAGGTCGGGCTGGCCAAGGGCGTTCGTCTGGGATACTTCGCCCAGCATCAGCTAGAGTATC
TTCGCGCCGACGAATCGCCACTGCAGCACTTAGCCCGCCTGGCGCCGCAGGAGAGCGAACAGCAGCTGCGCGACTATTTA
GGGGGCTTCGGTTTTAACGGCGATAAAGTCAGCGAGGCGACCGCGCGCTTTTCCGGCGGCGAGAAGGCGCGCCTGGTACT
GGCGCTGATCGTCTGGCAGCGTCCGAACCTGCTGCTGCTCGACGAACCGACCAACCATCTGGATCTGGACATGCGCCAGG
CGCTAACCGAAGCGCTGATCGATTTCGAGGGCGCGCTGGTGGTGGTCTCGCACGATCGCCATCTGCTGCGATCCACCACC
GACGATCTCTATCTGGTGCACGACGGCCAGGTCGAGCCGTTCGCCGGTGATCTGGACGACTACCAGCGCTGGATGATCGA
TCTGCAGCGCCAGGAAAACCAGGCGCCGGCGGATCAGGATGGCGCGCAAACGACCAACAGCGCCCAGGCCAGAAAGGATC
AGAAGCGGCGCGAGGCTGAGTTCCGCAGCCAGACTCAGCCGCTGCGCAAGCAGATCGCCGCGCAGGAAAAGCGTATGGAG
ACCCTGAGCGCCCAGCTCAATACTCTGGAGGAACGCCTCGCCGACAGCGCGCTGTACGATCCGGCGCGTAAAGAGGAGCT
AAACGACATTCTGCAGTGCCAAAGTCAGGCCAAGCTCGGTCTGGAAGAGGCGGAGCTGTGCTGGCTCGATGCGCAGGAGC
AGCTCGAAGCGATGTCCCGCGCCTTCACGGAGAGCGATAACGCCTGA

Upstream 100 bases:

>100_bases
CCGCGTTATTTACGTCGCCACAACGCCAATTTAACACACACTCAATAGACGACGCTTTATGATTGTTTTCTCATCGCTCC
AAATTCGTCGCGGCACCCGG

Downstream 100 bases:

>100_bases
GCGCCGCCTAGGCCGCCAGCGTATCCAGCGCCCGCCCCAGGCGGGCCATCCCCTCCTCGATCTCCGCCGTCTCGATCACC
AGAGACGGCGTAAAGCGCAG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNELSADGGNLTLPGNWAMAWVNQETPALETPALEYVLDGDREFRQL
EQQLDDANQRNDGNTIALIHGKLDAIAAWTIRARASSLLHGLGFSQEQLMQPVRSFSGGWRMRLNLAQALLCRSDLLLLD
EPTNHLDLDAVIWLERWLKSYPGTLILISHDRDFLDPIVDKIVHIEQQQLFEYSGNYSSFELQRAGKLAQQQAMYQSQQQ
RIAHLQSYIDRFKAKASKAKQAQSRVKMLERMERIAPAHVDNPFHFSFRAPESLPTPLLRMEHVSAGYGERTVLASIKLN
LVPGSRIGLLGRNGAGKSTLIKLLAGELAPQQGEVGLAKGVRLGYFAQHQLEYLRADESPLQHLARLAPQESEQQLRDYL
GGFGFNGDKVSEATARFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHDRHLLRSTT
DDLYLVHDGQVEPFAGDLDDYQRWMIDLQRQENQAPADQDGAQTTNSAQARKDQKRREAEFRSQTQPLRKQIAAQEKRME
TLSAQLNTLEERLADSALYDPARKEELNDILQCQSQAKLGLEEAELCWLDAQEQLEAMSRAFTESDNA

Sequences:

>Translated_628_residues
MLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNELSADGGNLTLPGNWAMAWVNQETPALETPALEYVLDGDREFRQL
EQQLDDANQRNDGNTIALIHGKLDAIAAWTIRARASSLLHGLGFSQEQLMQPVRSFSGGWRMRLNLAQALLCRSDLLLLD
EPTNHLDLDAVIWLERWLKSYPGTLILISHDRDFLDPIVDKIVHIEQQQLFEYSGNYSSFELQRAGKLAQQQAMYQSQQQ
RIAHLQSYIDRFKAKASKAKQAQSRVKMLERMERIAPAHVDNPFHFSFRAPESLPTPLLRMEHVSAGYGERTVLASIKLN
LVPGSRIGLLGRNGAGKSTLIKLLAGELAPQQGEVGLAKGVRLGYFAQHQLEYLRADESPLQHLARLAPQESEQQLRDYL
GGFGFNGDKVSEATARFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHDRHLLRSTT
DDLYLVHDGQVEPFAGDLDDYQRWMIDLQRQENQAPADQDGAQTTNSAQARKDQKRREAEFRSQTQPLRKQIAAQEKRME
TLSAQLNTLEERLADSALYDPARKEELNDILQCQSQAKLGLEEAELCWLDAQEQLEAMSRAFTESDNA
>Mature_628_residues
MLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNELSADGGNLTLPGNWAMAWVNQETPALETPALEYVLDGDREFRQL
EQQLDDANQRNDGNTIALIHGKLDAIAAWTIRARASSLLHGLGFSQEQLMQPVRSFSGGWRMRLNLAQALLCRSDLLLLD
EPTNHLDLDAVIWLERWLKSYPGTLILISHDRDFLDPIVDKIVHIEQQQLFEYSGNYSSFELQRAGKLAQQQAMYQSQQQ
RIAHLQSYIDRFKAKASKAKQAQSRVKMLERMERIAPAHVDNPFHFSFRAPESLPTPLLRMEHVSAGYGERTVLASIKLN
LVPGSRIGLLGRNGAGKSTLIKLLAGELAPQQGEVGLAKGVRLGYFAQHQLEYLRADESPLQHLARLAPQESEQQLRDYL
GGFGFNGDKVSEATARFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHDRHLLRSTT
DDLYLVHDGQVEPFAGDLDDYQRWMIDLQRQENQAPADQDGAQTTNSAQARKDQKRREAEFRSQTQPLRKQIAAQEKRME
TLSAQLNTLEERLADSALYDPARKEELNDILQCQSQAKLGLEEAELCWLDAQEQLEAMSRAFTESDNA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=526, Percent_Identity=39.3536121673004, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI27881506, Length=513, Percent_Identity=35.2826510721248, Blast_Score=308, Evalue=8e-84,
Organism=Homo sapiens, GI10947137, Length=513, Percent_Identity=35.2826510721248, Blast_Score=308, Evalue=1e-83,
Organism=Homo sapiens, GI69354671, Length=537, Percent_Identity=35.3817504655494, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI10947135, Length=537, Percent_Identity=35.3817504655494, Blast_Score=277, Evalue=2e-74,
Organism=Escherichia coli, GI1789751, Length=618, Percent_Identity=81.3915857605178, Blast_Score=1040, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=514, Percent_Identity=34.2412451361868, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1787182, Length=633, Percent_Identity=28.5939968404423, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI2367384, Length=526, Percent_Identity=31.1787072243346, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1788165, Length=196, Percent_Identity=35.7142857142857, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI87081782, Length=505, Percent_Identity=25.7425742574257, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI48994997, Length=221, Percent_Identity=27.6018099547511, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787164, Length=216, Percent_Identity=30.5555555555556, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=29.4117647058824, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790739, Length=220, Percent_Identity=27.7272727272727, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787758, Length=206, Percent_Identity=27.1844660194175, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789672, Length=220, Percent_Identity=25.4545454545455, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789891, Length=205, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787547, Length=211, Percent_Identity=25.1184834123223, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994883, Length=219, Percent_Identity=25.1141552511416, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787029, Length=215, Percent_Identity=23.7209302325581, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786803, Length=197, Percent_Identity=28.4263959390863, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788506, Length=266, Percent_Identity=24.812030075188, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=516, Percent_Identity=39.3410852713178, Blast_Score=357, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI17555318, Length=505, Percent_Identity=35.6435643564356, Blast_Score=323, Evalue=1e-88,
Organism=Caenorhabditis elegans, GI17559834, Length=534, Percent_Identity=34.0823970037453, Blast_Score=303, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17556528, Length=191, Percent_Identity=28.7958115183246, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=534, Percent_Identity=35.9550561797753, Blast_Score=344, Evalue=2e-95,
Organism=Saccharomyces cerevisiae, GI6320874, Length=514, Percent_Identity=34.6303501945525, Blast_Score=309, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6325030, Length=377, Percent_Identity=32.0954907161804, Blast_Score=165, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6324314, Length=393, Percent_Identity=28.498727735369, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6323278, Length=386, Percent_Identity=28.2383419689119, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24666836, Length=514, Percent_Identity=38.715953307393, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24642252, Length=529, Percent_Identity=36.2948960302458, Blast_Score=345, Evalue=7e-95,
Organism=Drosophila melanogaster, GI18859989, Length=529, Percent_Identity=36.2948960302458, Blast_Score=345, Evalue=7e-95,
Organism=Drosophila melanogaster, GI24641342, Length=530, Percent_Identity=36.4150943396226, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI116007184, Length=204, Percent_Identity=27.4509803921569, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221500365, Length=204, Percent_Identity=27.4509803921569, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70392; Mature: 70392

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNELSADGGNLTLPGNWAMAWVNQETP
CCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCC
ALETPALEYVLDGDREFRQLEQQLDDANQRNDGNTIALIHGKLDAIAAWTIRARASSLLH
CCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
GLGFSQEQLMQPVRSFSGGWRMRLNLAQALLCRSDLLLLDEPTNHLDLDAVIWLERWLKS
HCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHH
YPGTLILISHDRDFLDPIVDKIVHIEQQQLFEYSGNYSSFELQRAGKLAQQQAMYQSQQQ
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
RIAHLQSYIDRFKAKASKAKQAQSRVKMLERMERIAPAHVDNPFHFSFRAPESLPTPLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHH
MEHVSAGYGERTVLASIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPQQGEVGLAKG
HHHHCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHCC
VRLGYFAQHQLEYLRADESPLQHLARLAPQESEQQLRDYLGGFGFNGDKVSEATARFSGG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
EKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHDRHLLRSTT
CHHHHHEEEHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCC
DDLYLVHDGQVEPFAGDLDDYQRWMIDLQRQENQAPADQDGAQTTNSAQARKDQKRREAE
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
FRSQTQPLRKQIAAQEKRMETLSAQLNTLEERLADSALYDPARKEELNDILQCQSQAKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
LEEAELCWLDAQEQLEAMSRAFTESDNA
CCHHHEEECCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLDNASATINPGQKVGLVGKNGCGKSTLLALLKNELSADGGNLTLPGNWAMAWVNQETP
CCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCEEEEEECCCCC
ALETPALEYVLDGDREFRQLEQQLDDANQRNDGNTIALIHGKLDAIAAWTIRARASSLLH
CCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHH
GLGFSQEQLMQPVRSFSGGWRMRLNLAQALLCRSDLLLLDEPTNHLDLDAVIWLERWLKS
HCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHH
YPGTLILISHDRDFLDPIVDKIVHIEQQQLFEYSGNYSSFELQRAGKLAQQQAMYQSQQQ
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
RIAHLQSYIDRFKAKASKAKQAQSRVKMLERMERIAPAHVDNPFHFSFRAPESLPTPLLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHH
MEHVSAGYGERTVLASIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPQQGEVGLAKG
HHHHCCCCCCEEEEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCHHCC
VRLGYFAQHQLEYLRADESPLQHLARLAPQESEQQLRDYLGGFGFNGDKVSEATARFSGG
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCC
EKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHDRHLLRSTT
CHHHHHEEEHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCC
DDLYLVHDGQVEPFAGDLDDYQRWMIDLQRQENQAPADQDGAQTTNSAQARKDQKRREAE
CCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
FRSQTQPLRKQIAAQEKRMETLSAQLNTLEERLADSALYDPARKEELNDILQCQSQAKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
LEEAELCWLDAQEQLEAMSRAFTESDNA
CCHHHEEECCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]