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The map label for this gene is ywbI [H]

Identifier: 238921370

GI number: 238921370

Start: 3406676

End: 3407614

Strand: Direct

Name: ywbI [H]

Synonym: NT01EI_3514

Alternate gene names: 238921370

Gene position: 3406676-3407614 (Clockwise)

Preceding gene: 238921367

Following gene: 238921371

Centisome position: 89.36

GC content: 63.26

Gene sequence:

>939_bases
ATGGACGTGAGAACGTTACGTTATTTTGTTGAGGTGGTACGCCAGCATAGCTTCACCCGGGCGGCGGAAAAGCTGTTTGT
CACCCAGCCCACCATCAGCAAAATGCTGCGCAACCTGGAAGAGGAGCTGGGGTGCACCCTGCTGATCCGTGAGGGGCGTG
GCCTGCGCCTGACCGATAGCGGCAACGTGGTCTATCAACGAGCGCAGACGATCCTAGACCAATTTGGCCAGCTGAGAACC
GAGCTGGACGATCTCGGTGCCCTGAAAAAGGGGAGCCTGAAACTGGGTATTCCACCGATGGTCGGTACCCAAATGGCCGG
CCTGATCGGCGAATTCCGCCAGCGCTACCCGGGCATTGAGCTGCACATCGCCGAGTTCGGCGGGCTGACCGTCGAGCAGG
CGGTGCTCTCCGGCGAGCTGGATCTGGCGCTCACCGCCCTCTCTGCCCAGCCCGATCCGGCCATCGCCTCGCTGCCGCTG
TTCAGCCACCCGCTGTATGTATTGCTACCGCGCCAGGCGCCCTGGCTGACCCGCTCTGCCCTGGGCATGACCGATCTGGC
CCAGCAAAACATTCTGCTGTACAACGAGGACTTCGCCCTCTATCAGCAGCTGATGCAGGCCTTTTCCGCCGCCGGTGTGA
AGCCGCAAATCGCGGTACGCAGCGGTCAATGGGACTTTCTGGCCGCCATGGTGCAGGCCGGGGTGGGTATCGCCATCCTG
CCACAGCCGATCTGTCAGCGTCTGGATCCACACAGCCTGCTGTGGCTACCGCTCGCACCGACGCTCATGTGGCGACTGGG
GCTGATCTGGTGCCATGGCCGCTATCTGTCACACAGCGCTCAGGCGTGGATCGCCCGCTGCCGCGAGTTCTGGCCTGAGA
GGGACATGCACCCCGAGCGCCTGACCCAGCACGGTAACGGGACACCGCCGACGGCATAG

Upstream 100 bases:

>100_bases
TCGCACAGTATAGGCAAAGAAGATCCCGGGTATAAAATGAATTAAAATTATCGCCATCATTGATAAATGGCATACCTATT
CCTGTAAAGCGGAGTCCTGC

Downstream 100 bases:

>100_bases
CATCAAGATCCCCCCGCTCTCGCCGGGGCCAAGAGACAAAAAATCTATGGTCACCCCCATTTTTGCAACACTGATTTTTG
ATTATTGGTTGGCTTGCTTA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MDVRTLRYFVEVVRQHSFTRAAEKLFVTQPTISKMLRNLEEELGCTLLIREGRGLRLTDSGNVVYQRAQTILDQFGQLRT
ELDDLGALKKGSLKLGIPPMVGTQMAGLIGEFRQRYPGIELHIAEFGGLTVEQAVLSGELDLALTALSAQPDPAIASLPL
FSHPLYVLLPRQAPWLTRSALGMTDLAQQNILLYNEDFALYQQLMQAFSAAGVKPQIAVRSGQWDFLAAMVQAGVGIAIL
PQPICQRLDPHSLLWLPLAPTLMWRLGLIWCHGRYLSHSAQAWIARCREFWPERDMHPERLTQHGNGTPPTA

Sequences:

>Translated_312_residues
MDVRTLRYFVEVVRQHSFTRAAEKLFVTQPTISKMLRNLEEELGCTLLIREGRGLRLTDSGNVVYQRAQTILDQFGQLRT
ELDDLGALKKGSLKLGIPPMVGTQMAGLIGEFRQRYPGIELHIAEFGGLTVEQAVLSGELDLALTALSAQPDPAIASLPL
FSHPLYVLLPRQAPWLTRSALGMTDLAQQNILLYNEDFALYQQLMQAFSAAGVKPQIAVRSGQWDFLAAMVQAGVGIAIL
PQPICQRLDPHSLLWLPLAPTLMWRLGLIWCHGRYLSHSAQAWIARCREFWPERDMHPERLTQHGNGTPPTA
>Mature_312_residues
MDVRTLRYFVEVVRQHSFTRAAEKLFVTQPTISKMLRNLEEELGCTLLIREGRGLRLTDSGNVVYQRAQTILDQFGQLRT
ELDDLGALKKGSLKLGIPPMVGTQMAGLIGEFRQRYPGIELHIAEFGGLTVEQAVLSGELDLALTALSAQPDPAIASLPL
FSHPLYVLLPRQAPWLTRSALGMTDLAQQNILLYNEDFALYQQLMQAFSAAGVKPQIAVRSGQWDFLAAMVQAGVGIAIL
PQPICQRLDPHSLLWLPLAPTLMWRLGLIWCHGRYLSHSAQAWIARCREFWPERDMHPERLTQHGNGTPPTA

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=270, Percent_Identity=29.6296296296296, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790399, Length=275, Percent_Identity=30.1818181818182, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=28.1746031746032, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787530, Length=265, Percent_Identity=26.0377358490566, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787879, Length=279, Percent_Identity=25.089605734767, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1789506, Length=306, Percent_Identity=21.8954248366013, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI145693105, Length=307, Percent_Identity=24.1042345276873, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787806, Length=276, Percent_Identity=26.4492753623188, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788887, Length=247, Percent_Identity=28.7449392712551, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787601, Length=274, Percent_Identity=25.1824817518248, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=24.4, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=23.8683127572016, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788748, Length=290, Percent_Identity=25.8620689655172, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=24.3027888446215, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790262, Length=255, Percent_Identity=24.3137254901961, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786401, Length=158, Percent_Identity=31.0126582278481, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789173, Length=143, Percent_Identity=31.4685314685315, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789440, Length=156, Percent_Identity=30.1282051282051, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788481, Length=291, Percent_Identity=24.3986254295533, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693193, Length=251, Percent_Identity=25.8964143426295, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=241, Percent_Identity=25.3112033195021, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786713, Length=266, Percent_Identity=27.0676691729323, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789639, Length=166, Percent_Identity=27.710843373494, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34870; Mature: 34870

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRTLRYFVEVVRQHSFTRAAEKLFVTQPTISKMLRNLEEELGCTLLIREGRGLRLTDS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEECC
GNVVYQRAQTILDQFGQLRTELDDLGALKKGSLKLGIPPMVGTQMAGLIGEFRQRYPGIE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCE
LHIAEFGGLTVEQAVLSGELDLALTALSAQPDPAIASLPLFSHPLYVLLPRQAPWLTRSA
EEEECCCCCHHHHHHHCCCHHHEEEEECCCCCCCCEECCHHHCCEEEEECCCCCCHHHHH
LGMTDLAQQNILLYNEDFALYQQLMQAFSAAGVKPQIAVRSGQWDFLAAMVQAGVGIAIL
CCHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEC
PQPICQRLDPHSLLWLPLAPTLMWRLGLIWCHGRYLSHSAQAWIARCREFWPERDMHPER
CHHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
LTQHGNGTPPTA
HHHCCCCCCCCC
>Mature Secondary Structure
MDVRTLRYFVEVVRQHSFTRAAEKLFVTQPTISKMLRNLEEELGCTLLIREGRGLRLTDS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEECC
GNVVYQRAQTILDQFGQLRTELDDLGALKKGSLKLGIPPMVGTQMAGLIGEFRQRYPGIE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCE
LHIAEFGGLTVEQAVLSGELDLALTALSAQPDPAIASLPLFSHPLYVLLPRQAPWLTRSA
EEEECCCCCHHHHHHHCCCHHHEEEEECCCCCCCCEECCHHHCCEEEEECCCCCCHHHHH
LGMTDLAQQNILLYNEDFALYQQLMQAFSAAGVKPQIAVRSGQWDFLAAMVQAGVGIAIL
CCHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCEEEC
PQPICQRLDPHSLLWLPLAPTLMWRLGLIWCHGRYLSHSAQAWIARCREFWPERDMHPER
CHHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
LTQHGNGTPPTA
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]