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The map label for this gene is argI [H]

Identifier: 238921318

GI number: 238921318

Start: 3354984

End: 3355985

Strand: Direct

Name: argI [H]

Synonym: NT01EI_3462

Alternate gene names: 238921318

Gene position: 3354984-3355985 (Clockwise)

Preceding gene: 238921316

Following gene: 238921323

Centisome position: 88.0

GC content: 59.58

Gene sequence:

>1002_bases
ATGGATCAGCTTAATCAGCAGCACTTTCTGAGGTTACTGGATTTCACCCCGCAGCAAATTGCATATCTAATCAATCTGGC
CGCCGAGCTGAAACAAGCCAAAAAACAGGGGTGCGAACGCCCCCGTCTGCATGGGAAAAACATCGCGTTGATCTTTGAAA
AGGACTCCACCCGTACCCGCTGCTCCTTTGAGGTGGCCGCCTACGATCAGGGCGCCCACGTCACCTACCTCGGCCCCAGC
GGCAGCCAGATAGGCCATAAAGAGTCGATCAAGGATAGCGCGCGGGTGCTCGGCAGGCTGTATGACGCCATTCAATACCG
CGGCTTTGGCCAGCAGGTGGTGGAAACCCTGGCGCACTACGCCGGCGTACCGGTATGGAATGGCCTGACCGATGAGTTCC
ACCCCACGCAGATTTTGGCGGATCTGCTCACCATGAGCGAACACTGCGCCAAGCCTCTTTCCGCCATGAAGCTGGCCTAT
CTGGGCGACGCGCGCAATAACATGGGCAACTCACTGCTGGAAGGCGCGGCACTGATGGGGATGGAGCTGCGGCTGGTCGC
GCCCAGGGCCTACTGGCCGGAAGCCGGACTGATCGCCCAATGCCAGACCGTGGCGCAGCAAACCGGCGCCAAGCTGGTGC
TGACGGAGGACGTCGCCGAAGGGGTACTGGACGCCGACTTCCTGTATACCGATGTGTGGGTCTCCATGGGCGAACCCAAA
TCGGTCTGGCAGGAGCGCATTACCCAGCTGCTGCCATATCAGATCAACATGCAAACGCTACAGCTGAGCGGCAACCCGCA
GGTGAAGTTCCTGCACTGCCTACCCGCCTTCCACGACGAGATGACCGGCGTAGGGCAGCAGATGGCCGCGCAGTATGGGC
TGCACGATGGTATTGAGGTGACCGATGAGGTGTTTGAATCACCCCACAGCATCGTCTTCGATCAGGCGGAGAACCGCCTG
CATACCATCAAGGCGGTGATGGTGGCGACCCTGGGAGAATAA

Upstream 100 bases:

>100_bases
AAGACAATATTTCACGCTCGGGGGTTGAAAATGAATTTTAATACACATAATGTGAATATAAATTCATCACAACACACCCC
CACAGACGGAGATGTTCCAT

Downstream 100 bases:

>100_bases
TGGCGCGCGCAGCCTCTGAGGCAGCGCACCACGCGGCCAGCGGTCACTGCCGCTGGCCGCCGTAACCGCTACAGCAGGCC
GAGCGCCTGGGCATCCAGCT

Product: ornithine carbamoyltransferase chain I

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MDQLNQQHFLRLLDFTPQQIAYLINLAAELKQAKKQGCERPRLHGKNIALIFEKDSTRTRCSFEVAAYDQGAHVTYLGPS
GSQIGHKESIKDSARVLGRLYDAIQYRGFGQQVVETLAHYAGVPVWNGLTDEFHPTQILADLLTMSEHCAKPLSAMKLAY
LGDARNNMGNSLLEGAALMGMELRLVAPRAYWPEAGLIAQCQTVAQQTGAKLVLTEDVAEGVLDADFLYTDVWVSMGEPK
SVWQERITQLLPYQINMQTLQLSGNPQVKFLHCLPAFHDEMTGVGQQMAAQYGLHDGIEVTDEVFESPHSIVFDQAENRL
HTIKAVMVATLGE

Sequences:

>Translated_333_residues
MDQLNQQHFLRLLDFTPQQIAYLINLAAELKQAKKQGCERPRLHGKNIALIFEKDSTRTRCSFEVAAYDQGAHVTYLGPS
GSQIGHKESIKDSARVLGRLYDAIQYRGFGQQVVETLAHYAGVPVWNGLTDEFHPTQILADLLTMSEHCAKPLSAMKLAY
LGDARNNMGNSLLEGAALMGMELRLVAPRAYWPEAGLIAQCQTVAQQTGAKLVLTEDVAEGVLDADFLYTDVWVSMGEPK
SVWQERITQLLPYQINMQTLQLSGNPQVKFLHCLPAFHDEMTGVGQQMAAQYGLHDGIEVTDEVFESPHSIVFDQAENRL
HTIKAVMVATLGE
>Mature_333_residues
MDQLNQQHFLRLLDFTPQQIAYLINLAAELKQAKKQGCERPRLHGKNIALIFEKDSTRTRCSFEVAAYDQGAHVTYLGPS
GSQIGHKESIKDSARVLGRLYDAIQYRGFGQQVVETLAHYAGVPVWNGLTDEFHPTQILADLLTMSEHCAKPLSAMKLAY
LGDARNNMGNSLLEGAALMGMELRLVAPRAYWPEAGLIAQCQTVAQQTGAKLVLTEDVAEGVLDADFLYTDVWVSMGEPK
SVWQERITQLLPYQINMQTLQLSGNPQVKFLHCLPAFHDEMTGVGQQMAAQYGLHDGIEVTDEVFESPHSIVFDQAENRL
HTIKAVMVATLGE

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=332, Percent_Identity=38.5542168674699, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI18105007, Length=338, Percent_Identity=25.7396449704142, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1790703, Length=334, Percent_Identity=70.3592814371258, Blast_Score=503, Evalue=1e-143,
Organism=Escherichia coli, GI1786469, Length=334, Percent_Identity=70.3592814371258, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI48994908, Length=373, Percent_Identity=23.0563002680965, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI2367364, Length=344, Percent_Identity=26.453488372093, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322373, Length=329, Percent_Identity=32.2188449848024, Blast_Score=164, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322331, Length=160, Percent_Identity=29.375, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24642586, Length=339, Percent_Identity=24.188790560472, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 36999; Mature: 36999

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLNQQHFLRLLDFTPQQIAYLINLAAELKQAKKQGCERPRLHGKNIALIFEKDSTRTR
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCE
CSFEVAAYDQGAHVTYLGPSGSQIGHKESIKDSARVLGRLYDAIQYRGFGQQVVETLAHY
EEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGVPVWNGLTDEFHPTQILADLLTMSEHCAKPLSAMKLAYLGDARNNMGNSLLEGAALMG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
MELRLVAPRAYWPEAGLIAQCQTVAQQTGAKLVLTEDVAEGVLDADFLYTDVWVSMGEPK
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEHHHHCCHHHHHHHHHHHHHCCCCHH
SVWQERITQLLPYQINMQTLQLSGNPQVKFLHCLPAFHDEMTGVGQQMAAQYGLHDGIEV
HHHHHHHHHHCCCEECEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHH
TDEVFESPHSIVFDQAENRLHTIKAVMVATLGE
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDQLNQQHFLRLLDFTPQQIAYLINLAAELKQAKKQGCERPRLHGKNIALIFEKDSTRTR
CCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCE
CSFEVAAYDQGAHVTYLGPSGSQIGHKESIKDSARVLGRLYDAIQYRGFGQQVVETLAHY
EEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGVPVWNGLTDEFHPTQILADLLTMSEHCAKPLSAMKLAYLGDARNNMGNSLLEGAALMG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
MELRLVAPRAYWPEAGLIAQCQTVAQQTGAKLVLTEDVAEGVLDADFLYTDVWVSMGEPK
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEHHHHCCHHHHHHHHHHHHHCCCCHH
SVWQERITQLLPYQINMQTLQLSGNPQVKFLHCLPAFHDEMTGVGQQMAAQYGLHDGIEV
HHHHHHHHHHCCCEECEEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCHH
TDEVFESPHSIVFDQAENRLHTIKAVMVATLGE
HHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA