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The map label for this gene is speF [H]

Identifier: 238921268

GI number: 238921268

Start: 3297303

End: 3299465

Strand: Direct

Name: speF [H]

Synonym: NT01EI_3411

Alternate gene names: 238921268

Gene position: 3297303-3299465 (Clockwise)

Preceding gene: 238921256

Following gene: 238921269

Centisome position: 86.49

GC content: 62.14

Gene sequence:

>2163_bases
ATGGAAACATTAAAAATAGCGATCAGCGACAGCGTGATGCAGTGTATTAATACCCAGCGTAACCTTGTCGCTCCCGGAAA
CAGCGATCTTACCGACGTTGCCGCCGTGGTGCTGTCGGTACAGGATGCGCTGGGCGGCGTGCTGGATAAGGTCGAGCAGA
GCGCCTTTGGCCTGCCTGTCTTTGTCGCCGAGGCGGGCGACCAGTCTCTGCCGGCCGAGTATCTGCCGCGCCTGACCGGC
GTCTTTACCTGCGGCGACGGCAATCAGGATTTTTATGGAAAACAGCTGGAAAGTGCGGCACAGAAATATGAGGCCGAGCT
GCTGCCGCCGTTTTTCGGCAGCCTGCAGACCTACATCCGGCAGGGCAACGCCGCCTTTGACTGCCCGGGGCATCAGGGTG
GCCAGTTCTTCCGCCGCCACCCCACAGGCCGTCAGTTCTTCGACTACTTTGGCGAGGCCCTGTTCCGCGCCGATCTGTGC
AACGCCGACGTCTCCATGGGTGACCTGCTGATCCACGAAGGCGCCCCCTGCGCCGCCCAGCAGCACGCGGCCAAGGTGTT
CAACGCCGACAAGACCTACTTTGTGCTCAACGGCACCTCCTCTTCCAATAAAGTGGTGCTCAACGCACTGCTGGCGCCCG
GTGATCTGGTCCTCTTCGACCGTAATAACCATAAATCCAACCACCACGGCGCATTGATTCAGGCCGGTGCTACGCCGGTC
TACCTGGAAACCGCGCGTAACCCGTTCGGTTTCATCGGGGGCATCGACGCACACTGCTTTGAAGAGAAATACCTGCGTGA
CCTGGTGCGTGAGATCGCCCCGGCGCGCACCGGGGAACAACGGCCGTTCCGCCTGGCGGTTATCCAGCTCGGCACCTATG
ACGGCACCATCTACAACGCCCGCCAGGTGGTGGATAAGATAGGTCACCTGTGTGACTACATCCTGTTCGACTCCGCCTGG
GTTGGCTATGAGCAGTTCATCCCGATGATGAAAGAGTGCTCGCCGCTGCTGCTGGAGCTGAACGAGAACGATCCGGGGAT
CCTGGTGACCCAGTCGGTGCACAAACAGCAGGCCGGCTTCTCACAGACCTCGCAGATCCACAAAAAGGATCGTCATATCA
AGGGGCAGGCGCGCTATGTTAACCACAAGCGCCTGAACAACGCCTTTATGATGCATGCCTCCACCAGCCCGTTCTACCCG
CTGTTCGCCGCCCTGGACGTCAATGCCCGCATGCACGCCGGCGACAGCGGCAAGCGCATGTGGATGGAGTGCGTCCGGGT
GGGCATTGAAACCCGCAAGCTGCTGCTGCAGACCTGCCAGCACATCCGCCCCTTCGTCCCGGAGACCGTGGACGGCCGCC
CATGGGGTGCCTGCGACACCGAAGAGATGGCCAACGACCTGCGCTTCTTTAACTTTATCCCCGGTGAGCGCTGGCACGCC
TTTGAGGGCTATGCCGAGCACCAGTACTTTGTCGACCCGTGCAAGCTGATGCTGACCACCCCGGGTATCGATGCCAAGAG
CGGCGAATACCAGGCCTTTGGGGTGCCCGCGACCATTCTGGCCAACTTCCTGCGCGAAAACGGCATCGTGCCGGAGAAAT
GCGACCTGAACTCGATCCTGTTCCTGCTTACCCCGGCGGAGGACATGGCCAAGATGCAGCATCTGGTGGCCCAGATCGCC
CGCTTCGAGCGTCTGCTGGAGCAGGACGCCCCGCTGGCTGAGGTGCTGCCGTCCCTCTACCGCGCCAACGAGGCACGCTA
CCGCGGCTACACCCTGCGTCAGCTGTGCCAGGAGATGCACGACCTGTACGTCAGCCACGACGTGAAGCAGCTGCAGAAGG
AGATGTTCCGCAAGGCGCACTTCCCGCGGGTGGCGATGAATCCGCAGCAGGCCAACATCGCGTTCGTACGCGGCAACGTC
GAGCTGGTCTCCCTGGCGCAGGCCGAAGGCCGCATCGCGGCGGAGGGCGCACTGCCGTACCCACCGGGGGTGCTGTGCGT
GGTACCGGGGGAGGTCTGGGGCGGCTCGGTGCAGCGCTACTTCCTGGCGCTGGAAGAGGGCATCAACCTGCTGCCGGGCT
TCGCGCCGGAGCTGCAGGGGGTCTACATCCAACAGGATGAGGATGGCCGCAAGCGCGCCTATGGCTACATGATCAAGCAG
TAA

Upstream 100 bases:

>100_bases
TCTGCTGCTGCCATAAAAAATACTTACCAGAGAATTCAATTTGATTAAATTAAATTCCGTGGGATAGGTTTGTCTTAAAT
AATGCAATGAGACCAACAAA

Downstream 100 bases:

>100_bases
CAGCCTTTATATCGACATTACCAATAAAACAAGGTTGGCGGGGGGCCGCGGCTCCTGGGTTGCTCCTGCCCGGATCCCCG
CATTTTGAGAGAGAGAAACT

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
METLKIAISDSVMQCINTQRNLVAPGNSDLTDVAAVVLSVQDALGGVLDKVEQSAFGLPVFVAEAGDQSLPAEYLPRLTG
VFTCGDGNQDFYGKQLESAAQKYEAELLPPFFGSLQTYIRQGNAAFDCPGHQGGQFFRRHPTGRQFFDYFGEALFRADLC
NADVSMGDLLIHEGAPCAAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLAPGDLVLFDRNNHKSNHHGALIQAGATPV
YLETARNPFGFIGGIDAHCFEEKYLRDLVREIAPARTGEQRPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW
VGYEQFIPMMKECSPLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDRHIKGQARYVNHKRLNNAFMMHASTSPFYP
LFAALDVNARMHAGDSGKRMWMECVRVGIETRKLLLQTCQHIRPFVPETVDGRPWGACDTEEMANDLRFFNFIPGERWHA
FEGYAEHQYFVDPCKLMLTTPGIDAKSGEYQAFGVPATILANFLRENGIVPEKCDLNSILFLLTPAEDMAKMQHLVAQIA
RFERLLEQDAPLAEVLPSLYRANEARYRGYTLRQLCQEMHDLYVSHDVKQLQKEMFRKAHFPRVAMNPQQANIAFVRGNV
ELVSLAQAEGRIAAEGALPYPPGVLCVVPGEVWGGSVQRYFLALEEGINLLPGFAPELQGVYIQQDEDGRKRAYGYMIKQ

Sequences:

>Translated_720_residues
METLKIAISDSVMQCINTQRNLVAPGNSDLTDVAAVVLSVQDALGGVLDKVEQSAFGLPVFVAEAGDQSLPAEYLPRLTG
VFTCGDGNQDFYGKQLESAAQKYEAELLPPFFGSLQTYIRQGNAAFDCPGHQGGQFFRRHPTGRQFFDYFGEALFRADLC
NADVSMGDLLIHEGAPCAAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLAPGDLVLFDRNNHKSNHHGALIQAGATPV
YLETARNPFGFIGGIDAHCFEEKYLRDLVREIAPARTGEQRPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW
VGYEQFIPMMKECSPLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDRHIKGQARYVNHKRLNNAFMMHASTSPFYP
LFAALDVNARMHAGDSGKRMWMECVRVGIETRKLLLQTCQHIRPFVPETVDGRPWGACDTEEMANDLRFFNFIPGERWHA
FEGYAEHQYFVDPCKLMLTTPGIDAKSGEYQAFGVPATILANFLRENGIVPEKCDLNSILFLLTPAEDMAKMQHLVAQIA
RFERLLEQDAPLAEVLPSLYRANEARYRGYTLRQLCQEMHDLYVSHDVKQLQKEMFRKAHFPRVAMNPQQANIAFVRGNV
ELVSLAQAEGRIAAEGALPYPPGVLCVVPGEVWGGSVQRYFLALEEGINLLPGFAPELQGVYIQQDEDGRKRAYGYMIKQ
>Mature_720_residues
METLKIAISDSVMQCINTQRNLVAPGNSDLTDVAAVVLSVQDALGGVLDKVEQSAFGLPVFVAEAGDQSLPAEYLPRLTG
VFTCGDGNQDFYGKQLESAAQKYEAELLPPFFGSLQTYIRQGNAAFDCPGHQGGQFFRRHPTGRQFFDYFGEALFRADLC
NADVSMGDLLIHEGAPCAAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLAPGDLVLFDRNNHKSNHHGALIQAGATPV
YLETARNPFGFIGGIDAHCFEEKYLRDLVREIAPARTGEQRPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW
VGYEQFIPMMKECSPLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDRHIKGQARYVNHKRLNNAFMMHASTSPFYP
LFAALDVNARMHAGDSGKRMWMECVRVGIETRKLLLQTCQHIRPFVPETVDGRPWGACDTEEMANDLRFFNFIPGERWHA
FEGYAEHQYFVDPCKLMLTTPGIDAKSGEYQAFGVPATILANFLRENGIVPEKCDLNSILFLLTPAEDMAKMQHLVAQIA
RFERLLEQDAPLAEVLPSLYRANEARYRGYTLRQLCQEMHDLYVSHDVKQLQKEMFRKAHFPRVAMNPQQANIAFVRGNV
ELVSLAQAEGRIAAEGALPYPPGVLCVVPGEVWGGSVQRYFLALEEGINLLPGFAPELQGVYIQQDEDGRKRAYGYMIKQ

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=719, Percent_Identity=77.0514603616134, Blast_Score=1188, Evalue=0.0,
Organism=Escherichia coli, GI87082193, Length=719, Percent_Identity=67.8720445062587, Blast_Score=1039, Evalue=0.0,
Organism=Escherichia coli, GI1786384, Length=624, Percent_Identity=34.6153846153846, Blast_Score=326, Evalue=4e-90,
Organism=Escherichia coli, GI221142684, Length=678, Percent_Identity=30.9734513274336, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI1790573, Length=620, Percent_Identity=34.0322580645161, Blast_Score=319, Evalue=5e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 80375; Mature: 80375

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLKIAISDSVMQCINTQRNLVAPGNSDLTDVAAVVLSVQDALGGVLDKVEQSAFGLPV
CCEEEEEHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
FVAEAGDQSLPAEYLPRLTGVFTCGDGNQDFYGKQLESAAQKYEAELLPPFFGSLQTYIR
EEECCCCCCCCHHHHCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QGNAAFDCPGHQGGQFFRRHPTGRQFFDYFGEALFRADLCNADVSMGDLLIHEGAPCAAQ
CCCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHH
QHAAKVFNADKTYFVLNGTSSSNKVVLNALLAPGDLVLFDRNNHKSNHHGALIQAGATPV
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPFGFIGGIDAHCFEEKYLRDLVREIAPARTGEQRPFRLAVIQLGTYDGTIYNA
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCHHHH
RQVVDKIGHLCDYILFDSAWVGYEQFIPMMKECSPLLLELNENDPGILVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDRHIKGQARYVNHKRLNNAFMMHASTSPFYPLFAALDVNARMHAGDSGKRM
HHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCEEECCCCHHHH
WMECVRVGIETRKLLLQTCQHIRPFVPETVDGRPWGACDTEEMANDLRFFNFIPGERWHA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
FEGYAEHQYFVDPCKLMLTTPGIDAKSGEYQAFGVPATILANFLRENGIVPEKCDLNSIL
CCCCCCCCEEECCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAEDMAKMQHLVAQIARFERLLEQDAPLAEVLPSLYRANEARYRGYTLRQLCQEMH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHH
DLYVSHDVKQLQKEMFRKAHFPRVAMNPQQANIAFVRGNVELVSLAQAEGRIAAEGALPY
HHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCEEEEEEECCCCCEEECCCCCC
PPGVLCVVPGEVWGGSVQRYFLALEEGINLLPGFAPELQGVYIQQDEDGRKRAYGYMIKQ
CCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCC
>Mature Secondary Structure
METLKIAISDSVMQCINTQRNLVAPGNSDLTDVAAVVLSVQDALGGVLDKVEQSAFGLPV
CCEEEEEHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
FVAEAGDQSLPAEYLPRLTGVFTCGDGNQDFYGKQLESAAQKYEAELLPPFFGSLQTYIR
EEECCCCCCCCHHHHCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
QGNAAFDCPGHQGGQFFRRHPTGRQFFDYFGEALFRADLCNADVSMGDLLIHEGAPCAAQ
CCCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHH
QHAAKVFNADKTYFVLNGTSSSNKVVLNALLAPGDLVLFDRNNHKSNHHGALIQAGATPV
HHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPFGFIGGIDAHCFEEKYLRDLVREIAPARTGEQRPFRLAVIQLGTYDGTIYNA
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCHHHH
RQVVDKIGHLCDYILFDSAWVGYEQFIPMMKECSPLLLELNENDPGILVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDRHIKGQARYVNHKRLNNAFMMHASTSPFYPLFAALDVNARMHAGDSGKRM
HHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCEEECCCCHHHH
WMECVRVGIETRKLLLQTCQHIRPFVPETVDGRPWGACDTEEMANDLRFFNFIPGERWHA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
FEGYAEHQYFVDPCKLMLTTPGIDAKSGEYQAFGVPATILANFLRENGIVPEKCDLNSIL
CCCCCCCCEEECCEEEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAEDMAKMQHLVAQIARFERLLEQDAPLAEVLPSLYRANEARYRGYTLRQLCQEMH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCHHHHHHHHHHH
DLYVSHDVKQLQKEMFRKAHFPRVAMNPQQANIAFVRGNVELVSLAQAEGRIAAEGALPY
HHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEECCEEEEEEECCCCCEEECCCCCC
PPGVLCVVPGEVWGGSVQRYFLALEEGINLLPGFAPELQGVYIQQDEDGRKRAYGYMIKQ
CCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1939141; 8905232; 9278503 [H]