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The map label for this gene is tcp [H]

Identifier: 238921106

GI number: 238921106

Start: 3122569

End: 3124149

Strand: Reverse

Name: tcp [H]

Synonym: NT01EI_3245

Alternate gene names: 238921106

Gene position: 3124149-3122569 (Counterclockwise)

Preceding gene: 238921111

Following gene: 238921105

Centisome position: 81.95

GC content: 61.48

Gene sequence:

>1581_bases
ATGTTGGCGGCAGTACGCAGTTATTTTCAGCGAGTGACAATTGGGGGGCGGATCGTCATCTGCTTTGGCGTGGTACTGGT
ACTGGTGCTGTTGCTGGCATCGGTCAGCGTGTGGCAGGTTGGCAAGATTAAAAGCTCGCTGGAGCAGATTAACGATGTGA
ATAACGTGAAGCAACAGCTGGCGGTGGATCTGCGCGGCAGCGTGCACGATCGCGCTATTGCGCTGCGCGACGTCGTGCTG
GTGGAGCCGGATGCTCTGGCGCCTATCGTGCGGGATATTGCCCGGCTGGGGGGGGATTATCAGCGGGCCTGGCAGCGCTT
GGGGCAGCTGCGCAGCGGCAGTGCCGGATTTAGCGCAGAAGAGCAGCGGGTCTATAGCGAACTGGCGGCGACGGAGTCTC
AGACCTTGCCGCTGATCGCACAGGTGATCGCCCTGCGCGAGGCGGGGCAGCTTGAGCAGGCGTCTCAGCTGCTGCTGCAG
CAGGCTGGCCCCCGTTTTGTGACCTGGCTGAAGCAGATCAATGCTTTTATTACCATAGAGGATGGCTATAGCAATGCGCA
GACCCAGGTTGCGCGCGGGGTTTCCGAACACTTTCGCTTTCTGATGCTGGTACTGGCCGCGATCGCCGTCGCCACGGTGG
TGTTGATCGCCATGTCGATACGGAGCACCATCAGCGGTACGCTGGGCGCCGAACCGGTCGCGCTGCGCCGTCTGATCAAT
GCCATTGCCGCTGGCGATCTGCAATATCGACTGGCCATAGCGTCGGTGCCGGAGGGGAGTATTCTGGCCGCGACCCAGGA
GATGCAGCGGGCACTGACTAGCCTGCTGGGGCAGGTGAAAACGTCGGTACAGCAGGTTTCCGGTGTTAGCCAAGGCTTGA
CCGGTGGCAGCGGTGATCTGGCTTCTCGCAGCGACAGTCAGTCTTCGTCTATTCAACAGACGGCGGCGGCGATCGCGCAG
TTTGCGGCGGCGGTAAAGCGTAACTCCGAGAACGCCGGCCAGGCGGACAGGCTCGTGGCCGATGCCGGGGAGCAGGTGGC
CGAGGGAAGCCGGGTGATCCATGCCGTGGTAGCGGATATGGAGCACATCATCAAGGATTCTGCGGAGATCTCCGATATTA
CCCGAATTATCGAGTCCATCGCATTTCAGACTAATATCTTGGCGCTGAATGCGGCGGTTGAAGCGGCGCGGGCCGGCAGT
CAGGGGCGCGGTTTTGCAGTGGTAGCTGCAGAAGTTCGCTCTCTGGCCCAGCGTTCGTCGGTCGCCGCCCGCGACATCGG
CCAGCTGTTGGCTCGCTCGGTACAGCGGGTACGCAGTAACGCCCAGTCTGTTGATAGCGCCGATCGCTGTATGACCCAAA
TCGATGCGGCGATGCAGCAGGTGAAATGCGCGGTGAACCTGATCAGCGCAGACTCCGCCGAGCAGGCCGGAACGGTGGAT
GGCGTCGTCAGTGCGGTGGCCTTTATGGACAGCGGTATTCGTCAGAACGCGGCCCTTTCAGAGCAGTTGGCGGGCGATGC
CCGTGCGCTGGAGGAACACGCCCGGTCACTGCATGGTACCATCGCCCAGTTCCGTATCTAA

Upstream 100 bases:

>100_bases
GATTACGTTGGCGATCGGGGCGCTGGGGTTACCTCACGACAGGATAACGATAAAACCTATTTAGCCGATGCGCGGTCGGT
CTTTTATTTGAGGGAAAGTC

Downstream 100 bases:

>100_bases
GCCCTGAGCATCCGTTAGGGCGCCATTTCACCGCCCCGCGTTGCGGGCGGCGAAATGGTTTTATTTCACGTCATCATTTC
CTTTTTTATCTATTACTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 526; Mature: 526

Protein sequence:

>526_residues
MLAAVRSYFQRVTIGGRIVICFGVVLVLVLLLASVSVWQVGKIKSSLEQINDVNNVKQQLAVDLRGSVHDRAIALRDVVL
VEPDALAPIVRDIARLGGDYQRAWQRLGQLRSGSAGFSAEEQRVYSELAATESQTLPLIAQVIALREAGQLEQASQLLLQ
QAGPRFVTWLKQINAFITIEDGYSNAQTQVARGVSEHFRFLMLVLAAIAVATVVLIAMSIRSTISGTLGAEPVALRRLIN
AIAAGDLQYRLAIASVPEGSILAATQEMQRALTSLLGQVKTSVQQVSGVSQGLTGGSGDLASRSDSQSSSIQQTAAAIAQ
FAAAVKRNSENAGQADRLVADAGEQVAEGSRVIHAVVADMEHIIKDSAEISDITRIIESIAFQTNILALNAAVEAARAGS
QGRGFAVVAAEVRSLAQRSSVAARDIGQLLARSVQRVRSNAQSVDSADRCMTQIDAAMQQVKCAVNLISADSAEQAGTVD
GVVSAVAFMDSGIRQNAALSEQLAGDARALEEHARSLHGTIAQFRI

Sequences:

>Translated_526_residues
MLAAVRSYFQRVTIGGRIVICFGVVLVLVLLLASVSVWQVGKIKSSLEQINDVNNVKQQLAVDLRGSVHDRAIALRDVVL
VEPDALAPIVRDIARLGGDYQRAWQRLGQLRSGSAGFSAEEQRVYSELAATESQTLPLIAQVIALREAGQLEQASQLLLQ
QAGPRFVTWLKQINAFITIEDGYSNAQTQVARGVSEHFRFLMLVLAAIAVATVVLIAMSIRSTISGTLGAEPVALRRLIN
AIAAGDLQYRLAIASVPEGSILAATQEMQRALTSLLGQVKTSVQQVSGVSQGLTGGSGDLASRSDSQSSSIQQTAAAIAQ
FAAAVKRNSENAGQADRLVADAGEQVAEGSRVIHAVVADMEHIIKDSAEISDITRIIESIAFQTNILALNAAVEAARAGS
QGRGFAVVAAEVRSLAQRSSVAARDIGQLLARSVQRVRSNAQSVDSADRCMTQIDAAMQQVKCAVNLISADSAEQAGTVD
GVVSAVAFMDSGIRQNAALSEQLAGDARALEEHARSLHGTIAQFRI
>Mature_526_residues
MLAAVRSYFQRVTIGGRIVICFGVVLVLVLLLASVSVWQVGKIKSSLEQINDVNNVKQQLAVDLRGSVHDRAIALRDVVL
VEPDALAPIVRDIARLGGDYQRAWQRLGQLRSGSAGFSAEEQRVYSELAATESQTLPLIAQVIALREAGQLEQASQLLLQ
QAGPRFVTWLKQINAFITIEDGYSNAQTQVARGVSEHFRFLMLVLAAIAVATVVLIAMSIRSTISGTLGAEPVALRRLIN
AIAAGDLQYRLAIASVPEGSILAATQEMQRALTSLLGQVKTSVQQVSGVSQGLTGGSGDLASRSDSQSSSIQQTAAAIAQ
FAAAVKRNSENAGQADRLVADAGEQVAEGSRVIHAVVADMEHIIKDSAEISDITRIIESIAFQTNILALNAAVEAARAGS
QGRGFAVVAAEVRSLAQRSSVAARDIGQLLARSVQRVRSNAQSVDSADRCMTQIDAAMQQVKCAVNLISADSAEQAGTVD
GVVSAVAFMDSGIRQNAALSEQLAGDARALEEHARSLHGTIAQFRI

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=289, Percent_Identity=40.8304498269896, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI1788195, Length=262, Percent_Identity=42.7480916030534, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI2367378, Length=266, Percent_Identity=42.8571428571429, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1788194, Length=365, Percent_Identity=35.6164383561644, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789453, Length=230, Percent_Identity=41.304347826087, Blast_Score=148, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55704; Mature: 55704

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00656 GLYCOSYL_HYDROL_F6_2 ; PS00136 SUBTILASE_ASP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAAVRSYFQRVTIGGRIVICFGVVLVLVLLLASVSVWQVGKIKSSLEQINDVNNVKQQL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDLRGSVHDRAIALRDVVLVEPDALAPIVRDIARLGGDYQRAWQRLGQLRSGSAGFSAE
HHHHCCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHH
EQRVYSELAATESQTLPLIAQVIALREAGQLEQASQLLLQQAGPRFVTWLKQINAFITIE
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCEEEEEE
DGYSNAQTQVARGVSEHFRFLMLVLAAIAVATVVLIAMSIRSTISGTLGAEPVALRRLIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AIAAGDLQYRLAIASVPEGSILAATQEMQRALTSLLGQVKTSVQQVSGVSQGLTGGSGDL
HHHHCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ASRSDSQSSSIQQTAAAIAQFAAAVKRNSENAGQADRLVADAGEQVAEGSRVIHAVVADM
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHIIKDSAEISDITRIIESIAFQTNILALNAAVEAARAGSQGRGFAVVAAEVRSLAQRSS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VAARDIGQLLARSVQRVRSNAQSVDSADRCMTQIDAAMQQVKCAVNLISADSAEQAGTVD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHH
GVVSAVAFMDSGIRQNAALSEQLAGDARALEEHARSLHGTIAQFRI
HHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAAVRSYFQRVTIGGRIVICFGVVLVLVLLLASVSVWQVGKIKSSLEQINDVNNVKQQL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDLRGSVHDRAIALRDVVLVEPDALAPIVRDIARLGGDYQRAWQRLGQLRSGSAGFSAE
HHHHCCCHHHHHHHHHHHHEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHH
EQRVYSELAATESQTLPLIAQVIALREAGQLEQASQLLLQQAGPRFVTWLKQINAFITIE
HHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCEEEEEE
DGYSNAQTQVARGVSEHFRFLMLVLAAIAVATVVLIAMSIRSTISGTLGAEPVALRRLIN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AIAAGDLQYRLAIASVPEGSILAATQEMQRALTSLLGQVKTSVQQVSGVSQGLTGGSGDL
HHHHCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ASRSDSQSSSIQQTAAAIAQFAAAVKRNSENAGQADRLVADAGEQVAEGSRVIHAVVADM
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EHIIKDSAEISDITRIIESIAFQTNILALNAAVEAARAGSQGRGFAVVAAEVRSLAQRSS
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VAARDIGQLLARSVQRVRSNAQSVDSADRCMTQIDAAMQQVKCAVNLISADSAEQAGTVD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHH
GVVSAVAFMDSGIRQNAALSEQLAGDARALEEHARSLHGTIAQFRI
HHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]