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The map label for this gene is iscR

Identifier: 238921054

GI number: 238921054

Start: 3064001

End: 3064498

Strand: Reverse

Name: iscR

Synonym: NT01EI_3184

Alternate gene names: 238921054

Gene position: 3064498-3064001 (Counterclockwise)

Preceding gene: 238921055

Following gene: 238921053

Centisome position: 80.38

GC content: 57.43

Gene sequence:

>498_bases
ATGAGACTGACATCCAAAGGGCGTTATGCCGTAACAGCCATGCTCGATGTGGCGCTTCACTCCCAGGAAGGACCGGTACC
GCTGGCGGATATTTCAGAACGCCAGGGGATCTCGCTTTCTTATCTGGAGCAGCTGTTCTCCCGCCTGCGCAAAAATGGTC
TGGTGGCCAGCGTACGGGGTCCTGGTGGCGGTTACCTGCTGGGAAAAGAGACCAGTGAGATCGCTATTGGCGCGGTGATC
ACCGCCGTGGATGAGTCGGTGGATGCAACCCGCTGCCAGGGGAAAGAGGGCTGTCAGGGGGGAACCCGCTGCCTGACCCA
CACGTTGTGGCGCGATCTCAGCGAGCGTATCAGCGGTTTTCTAAACAATATTTCGCTGGCGGAGCTGGTCAATAATCAGG
AAGTCATGGATGTGGCTGACCGACAGGATATTGATGCACGGCGCAGCGTTGTCGCTGCCGGGCATCAGGATACGATTAAC
GTGAACCTGCGTGCATAA

Upstream 100 bases:

>100_bases
TAGTAGGATAAATAGTTGACTGAAATAGTCGGGAATGAGAGGATGAAACCGTTGAGCAACACTGTGTGTTTCACTCTTTT
TCCCAAAGGGGCTATTAGCC

Downstream 100 bases:

>100_bases
GCGCGGGCACGGAGTTGAATTATCACCCGTAGGCAAATCATTTTTGGAAGTGATGTACGGAGCAAAAGAATGAAATTACC
GATTTATATGGACTACTCCG

Product: iron-sulfur cluster assembly transcription factor IscR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MRLTSKGRYAVTAMLDVALHSQEGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKETSEIAIGAVI
TAVDESVDATRCQGKEGCQGGTRCLTHTLWRDLSERISGFLNNISLAELVNNQEVMDVADRQDIDARRSVVAAGHQDTIN
VNLRA

Sequences:

>Translated_165_residues
MRLTSKGRYAVTAMLDVALHSQEGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKETSEIAIGAVI
TAVDESVDATRCQGKEGCQGGTRCLTHTLWRDLSERISGFLNNISLAELVNNQEVMDVADRQDIDARRSVVAAGHQDTIN
VNLRA
>Mature_165_residues
MRLTSKGRYAVTAMLDVALHSQEGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKETSEIAIGAVI
TAVDESVDATRCQGKEGCQGGTRCLTHTLWRDLSERISGFLNNISLAELVNNQEVMDVADRQDIDARRSVVAAGHQDTIN
VNLRA

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788880, Length=166, Percent_Identity=78.3132530120482, Blast_Score=234, Evalue=2e-63,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): ISCR_EDWI9 (C5BEU6)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934569.1
- ProteinModelPortal:   C5BEU6
- GeneID:   7958702
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3184
- OMA:   QHISLSY
- ProtClustDB:   CLSK2813573
- HAMAP:   MF_01176
- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR02010
- TIGRFAMs:   TIGR00738

Pfam domain/function: PF02082 Rrf2

EC number: NA

Molecular weight: Translated: 17823; Mature: 17823

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS01332 HTH_RRF2_1; PS51197 HTH_RRF2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTSKGRYAVTAMLDVALHSQEGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRG
CCCCCCCCEEHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PGGGYLLGKETSEIAIGAVITAVDESVDATRCQGKEGCQGGTRCLTHTLWRDLSERISGF
CCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LNNISLAELVNNQEVMDVADRQDIDARRSVVAAGHQDTINVNLRA
HHCCHHHHHHCCCHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEEC
>Mature Secondary Structure
MRLTSKGRYAVTAMLDVALHSQEGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRG
CCCCCCCCEEHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PGGGYLLGKETSEIAIGAVITAVDESVDATRCQGKEGCQGGTRCLTHTLWRDLSERISGF
CCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LNNISLAELVNNQEVMDVADRQDIDARRSVVAAGHQDTINVNLRA
HHCCHHHHHHCCCHHHHHHCCCCCHHHHHHHHCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA