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The map label for this gene is nagC [H]

Identifier: 238920791

GI number: 238920791

Start: 2803862

End: 2805088

Strand: Direct

Name: nagC [H]

Synonym: NT01EI_2910

Alternate gene names: 238920791

Gene position: 2803862-2805088 (Clockwise)

Preceding gene: 238920790

Following gene: 238920793

Centisome position: 73.55

GC content: 61.12

Gene sequence:

>1227_bases
ATGGCCACTGGCGGACAGGGACAAATTGGTAATGTCGATCTGGTAAAGCAGCTGAACAGCGCAGCGGTCTACCGCCTGAT
CGATCAGCAGGGACCGATCTCACGTATTCAGATTGCCGAATACAGCCAGCTGGCCCCCGCCAGCGTCACAAAAATCACCC
GCCATCTGCTGGAGCGCGGGCTGATCAAAGAGGTCGATCAGCAGGCCTCCACCGGTGGGCGGCGCGCTATCTCCATCGTC
ACCGAGACGCGCCACTTCCAGGCTATTGCCATTCGGCTGGGCCGCTATGACGCCACCATCACCCTGTATGACCTCAGCGG
CAAAGTGCTGGCAGAGACGCACTACCCGCTGCCGCAGCGTACCCAGGAGACCGTCGAGCACGCCCTGTTTCAGGCCATCG
ACCACTTTATAAACGATTACCAGCGCAAGATCCGCGAGCTTATTGCCATCGCCCTGATGCTGCCCGGCCTGGTCGATCCG
GAGCTCGGGATCGTCCGCTACATGCCGCACATCACCGTCAGCGACTGGCCGCTGGTTGAACGTCTGCAGGCGCGCTTCCG
CCTGGCCTGCTTTATCGGTCACGATATCCGCAGCCTGGCGCTGGCTGAACACTACTTCGGCGCCAGCCGTGACTGCCGGG
ATTCGATCCTGGTGCGGCTGCACCGCGGCACCGGTGCCGGGATCATCGTGGATGAGAATATCTTTCTCGGCAGCAACGGC
AACGTCGGTGAGATTGGCCATATCCAGATAGATCCGCTGGGAGAACGCTGCCACTGTGGTAACTTTGGCTGTCTGGAGAC
CGTGGCGGCCAATGCGGCTATCGAACAACATACCCGCCGCCTGCTGGAGCAGGGCTACCCCAGCAGCCTGACGGTTGACA
ACTGTACCATCAACACGATTTGTCGGGCCGCCAACCGCGGCGATCCCTTGGCCGTAGAGGTGATTGCACGGGTGGGTCAC
TACCTGGGGCGCGCCATCGCCATCACCATCAACCTGTTCAACCCACAGAAGGTCATCATCGCCGGCGAGATAACCGAAGC
GGACAAGATCCTGCTGCCGGCCATTCAGCGCTGCATCCAGACCCAGGCACTGAAGGAGTTCCGCCACAATCTGCCGGTGG
TCACCTCTGAACTGAGCCACCGCTCCGCCATCGGCGCCTTTGCACTGGTCAAGCGCGCCATGCTGAACGGTGTGCTGCTA
CAGCGTCTGCTGGAGCATCACAACTGA

Upstream 100 bases:

>100_bases
ACGGCATTTACCCGCGACTTCCAGGTAACCACGACCATTGTTAACGGCGAAACCGTCTACCAGCGCGGCGGTTGAATGAC
AACACACAGGTGAGAGAGTG

Downstream 100 bases:

>100_bases
GTCGCACACGGCGCTTCTGTTATACCAAGGGCTGCAGCGCAATAGAGATCCGGCAGCGCTTGCGGCCGGTGTTCTTTTTA
TGGAAAAAGATCGCCGCATC

Product: N-acetylglucosamine repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MATGGQGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQIAEYSQLAPASVTKITRHLLERGLIKEVDQQASTGGRRAISIV
TETRHFQAIAIRLGRYDATITLYDLSGKVLAETHYPLPQRTQETVEHALFQAIDHFINDYQRKIRELIAIALMLPGLVDP
ELGIVRYMPHITVSDWPLVERLQARFRLACFIGHDIRSLALAEHYFGASRDCRDSILVRLHRGTGAGIIVDENIFLGSNG
NVGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEQHTRRLLEQGYPSSLTVDNCTINTICRAANRGDPLAVEVIARVGH
YLGRAIAITINLFNPQKVIIAGEITEADKILLPAIQRCIQTQALKEFRHNLPVVTSELSHRSAIGAFALVKRAMLNGVLL
QRLLEHHN

Sequences:

>Translated_408_residues
MATGGQGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQIAEYSQLAPASVTKITRHLLERGLIKEVDQQASTGGRRAISIV
TETRHFQAIAIRLGRYDATITLYDLSGKVLAETHYPLPQRTQETVEHALFQAIDHFINDYQRKIRELIAIALMLPGLVDP
ELGIVRYMPHITVSDWPLVERLQARFRLACFIGHDIRSLALAEHYFGASRDCRDSILVRLHRGTGAGIIVDENIFLGSNG
NVGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEQHTRRLLEQGYPSSLTVDNCTINTICRAANRGDPLAVEVIARVGH
YLGRAIAITINLFNPQKVIIAGEITEADKILLPAIQRCIQTQALKEFRHNLPVVTSELSHRSAIGAFALVKRAMLNGVLL
QRLLEHHN
>Mature_407_residues
ATGGQGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQIAEYSQLAPASVTKITRHLLERGLIKEVDQQASTGGRRAISIVT
ETRHFQAIAIRLGRYDATITLYDLSGKVLAETHYPLPQRTQETVEHALFQAIDHFINDYQRKIRELIAIALMLPGLVDPE
LGIVRYMPHITVSDWPLVERLQARFRLACFIGHDIRSLALAEHYFGASRDCRDSILVRLHRGTGAGIIVDENIFLGSNGN
VGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEQHTRRLLEQGYPSSLTVDNCTINTICRAANRGDPLAVEVIARVGHY
LGRAIAITINLFNPQKVIIAGEITEADKILLPAIQRCIQTQALKEFRHNLPVVTSELSHRSAIGAFALVKRAMLNGVLLQ
RLLEHHN

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=268, Percent_Identity=22.3880597014925, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI298566325, Length=268, Percent_Identity=22.3880597014925, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI190014632, Length=268, Percent_Identity=22.3880597014925, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4885285, Length=268, Percent_Identity=22.3880597014925, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786891, Length=406, Percent_Identity=77.3399014778325, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1787878, Length=402, Percent_Identity=40.7960199004975, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI87082127, Length=346, Percent_Identity=23.9884393063584, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081733, Length=272, Percent_Identity=22.7941176470588, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790522, Length=268, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 45143; Mature: 45012

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGGQGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQIAEYSQLAPASVTKITRHLLERG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHH
LIKEVDQQASTGGRRAISIVTETRHFQAIAIRLGRYDATITLYDLSGKVLAETHYPLPQR
HHHHHHHHHCCCCCEEEEEEECCHHHEEEEEEECCEEEEEEEEECCCCEEEECCCCCCCH
TQETVEHALFQAIDHFINDYQRKIRELIAIALMLPGLVDPELGIVRYMPHITVSDWPLVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHH
RLQARFRLACFIGHDIRSLALAEHYFGASRDCRDSILVRLHRGTGAGIIVDENIFLGSNG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHEEEEECCCCCEEEEECCEEECCCC
NVGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEQHTRRLLEQGYPSSLTVDNCTINTI
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHH
CRAANRGDPLAVEVIARVGHYLGRAIAITINLFNPQKVIIAGEITEADKILLPAIQRCIQ
HHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHH
TQALKEFRHNLPVVTSELSHRSAIGAFALVKRAMLNGVLLQRLLEHHN
HHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATGGQGQIGNVDLVKQLNSAAVYRLIDQQGPISRIQIAEYSQLAPASVTKITRHLLERG
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHCCCHHHHHHHHHHHHHH
LIKEVDQQASTGGRRAISIVTETRHFQAIAIRLGRYDATITLYDLSGKVLAETHYPLPQR
HHHHHHHHHCCCCCEEEEEEECCHHHEEEEEEECCEEEEEEEEECCCCEEEECCCCCCCH
TQETVEHALFQAIDHFINDYQRKIRELIAIALMLPGLVDPELGIVRYMPHITVSDWPLVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHH
RLQARFRLACFIGHDIRSLALAEHYFGASRDCRDSILVRLHRGTGAGIIVDENIFLGSNG
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHEEEEECCCCCEEEEECCEEECCCC
NVGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEQHTRRLLEQGYPSSLTVDNCTINTI
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHH
CRAANRGDPLAVEVIARVGHYLGRAIAITINLFNPQKVIIAGEITEADKILLPAIQRCIQ
HHHCCCCCCHHHHHHHHHHHHHCCEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHH
TQALKEFRHNLPVVTSELSHRSAIGAFALVKRAMLNGVLLQRLLEHHN
HHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]