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The map label for this gene is nagA [H]

Identifier: 238920790

GI number: 238920790

Start: 2802682

End: 2803836

Strand: Direct

Name: nagA [H]

Synonym: NT01EI_2909

Alternate gene names: 238920790

Gene position: 2802682-2803836 (Clockwise)

Preceding gene: 238920789

Following gene: 238920791

Centisome position: 73.52

GC content: 60.78

Gene sequence:

>1155_bases
ATGTACGCCTTAACTCACTGTCGGATTTATACCGGCCACGATATTCTTGACGACCATGCTGTGGTGATCGCCAATGGTTT
AATTGAAAAAATCTGTCCCGAGTCTGCGCTCGCACCGGATATCACCACCCGCGATCTGGGCGGCGCCATCCTGGCCCCCG
GTTTTATCGACGTTCAGCTCAACGGCTGCGGTGGCGTGCAGTTTAACGACAGCGAAGAGGCCGTCAGCGAGCAGACGCTG
GAGATCATGCAGCGCACCAACGAGCGCGCCGGCTGCACCAGCTACCTGCCGACGCTGATCACCTGCAGCGACGCCATGAT
GCAGCGCGGCATTACGGTGATGCACTCCTATCTGCGCCGTCACCGTAACCAGGCGCTGGGCCTGCATATTGAAGGGCCCT
ATATCAGCCCGGAGAAAAAGGGTACCCACAATCCGCGCTATATCCGCCGCCCGGATCGCGCCATGCTTGACTTTATCTGC
AGCCACGCCGAGGCCATCGTCAAGGTGACCATGGCGCCGGAGATGAGCGACGACGCGGCCATTCAACAGCTGCGCGCCGC
CGGGATCGTGGTCTCCGCCGGCCACTCCAACGCCAGCTACCAGGAGGCACGCCGCGGCTTCGCCGCCGGAATGCGCTTTG
CCACCCACCTCTACAATGCGATGCCGGCGATCAGTGGCCGCGCCCCGGGGCTGATGGGCGCCATCTTCGACACCCCAGAA
GTGTATACCGGCATCATCGCCGACGGACACCACGTGGCCTGGCCGAACATCCGCATGGCGAAAAAGCTTAAGGGTGACCA
CCTGGTGCTGGTCACCGATGCCACCGCGCCGGCAGGTTCAAATATTGACAGCTTCATTTTCGCGGGGAAAACAGTATATT
ACCGCAATGGGCTGGTAGTGGATGAAAATGGTACACTGAGCGGATCGGCGCTGACCATGATCGGGGCGGTACAGAACAGC
GTTGAACATGTCGGCATTGCACTGGATGAAGCACTGCGTATGGCCAGCCTCTATCCGGCGCGCGCCATCGGTGTCGCGCA
GCGGCTGGGCAGCATCGAACCGGGTAAGGTCGCCAACCTGACGGCATTTACCCGCGACTTCCAGGTAACCACGACCATTG
TTAACGGCGAAACCGTCTACCAGCGCGGCGGTTGA

Upstream 100 bases:

>100_bases
CCGGCAACCATGGAGCTGAAAGTTAAAACCGTTAACTATTTCCGCGAGCTCGAAGCGGAAAATATGAAAGATCTCTGATA
ATTACGTCCGGGGGAATGTG

Downstream 100 bases:

>100_bases
ATGACAACACACAGGTGAGAGAGTGATGGCCACTGGCGGACAGGGACAAATTGGTAATGTCGATCTGGTAAAGCAGCTGA
ACAGCGCAGCGGTCTACCGC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MYALTHCRIYTGHDILDDHAVVIANGLIEKICPESALAPDITTRDLGGAILAPGFIDVQLNGCGGVQFNDSEEAVSEQTL
EIMQRTNERAGCTSYLPTLITCSDAMMQRGITVMHSYLRRHRNQALGLHIEGPYISPEKKGTHNPRYIRRPDRAMLDFIC
SHAEAIVKVTMAPEMSDDAAIQQLRAAGIVVSAGHSNASYQEARRGFAAGMRFATHLYNAMPAISGRAPGLMGAIFDTPE
VYTGIIADGHHVAWPNIRMAKKLKGDHLVLVTDATAPAGSNIDSFIFAGKTVYYRNGLVVDENGTLSGSALTMIGAVQNS
VEHVGIALDEALRMASLYPARAIGVAQRLGSIEPGKVANLTAFTRDFQVTTTIVNGETVYQRGG

Sequences:

>Translated_384_residues
MYALTHCRIYTGHDILDDHAVVIANGLIEKICPESALAPDITTRDLGGAILAPGFIDVQLNGCGGVQFNDSEEAVSEQTL
EIMQRTNERAGCTSYLPTLITCSDAMMQRGITVMHSYLRRHRNQALGLHIEGPYISPEKKGTHNPRYIRRPDRAMLDFIC
SHAEAIVKVTMAPEMSDDAAIQQLRAAGIVVSAGHSNASYQEARRGFAAGMRFATHLYNAMPAISGRAPGLMGAIFDTPE
VYTGIIADGHHVAWPNIRMAKKLKGDHLVLVTDATAPAGSNIDSFIFAGKTVYYRNGLVVDENGTLSGSALTMIGAVQNS
VEHVGIALDEALRMASLYPARAIGVAQRLGSIEPGKVANLTAFTRDFQVTTTIVNGETVYQRGG
>Mature_384_residues
MYALTHCRIYTGHDILDDHAVVIANGLIEKICPESALAPDITTRDLGGAILAPGFIDVQLNGCGGVQFNDSEEAVSEQTL
EIMQRTNERAGCTSYLPTLITCSDAMMQRGITVMHSYLRRHRNQALGLHIEGPYISPEKKGTHNPRYIRRPDRAMLDFIC
SHAEAIVKVTMAPEMSDDAAIQQLRAAGIVVSAGHSNASYQEARRGFAAGMRFATHLYNAMPAISGRAPGLMGAIFDTPE
VYTGIIADGHHVAWPNIRMAKKLKGDHLVLVTDATAPAGSNIDSFIFAGKTVYYRNGLVVDENGTLSGSALTMIGAVQNS
VEHVGIALDEALRMASLYPARAIGVAQRLGSIEPGKVANLTAFTRDFQVTTTIVNGETVYQRGG

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=421, Percent_Identity=31.5914489311164, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI224922791, Length=419, Percent_Identity=31.0262529832936, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI1786892, Length=379, Percent_Identity=68.3377308707124, Blast_Score=551, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI17553768, Length=351, Percent_Identity=31.3390313390313, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI19920392, Length=401, Percent_Identity=31.1720698254364, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281361140, Length=415, Percent_Identity=30.1204819277108, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41368; Mature: 41368

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALTHCRIYTGHDILDDHAVVIANGLIEKICPESALAPDITTRDLGGAILAPGFIDVQL
CCEEEEEEEEECCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEE
NGCGGVQFNDSEEAVSEQTLEIMQRTNERAGCTSYLPTLITCSDAMMQRGITVMHSYLRR
CCCCCCEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HRNQALGLHIEGPYISPEKKGTHNPRYIRRPDRAMLDFICSHAEAIVKVTMAPEMSDDAA
HCCCEEEEEEECCEECCCCCCCCCCCCEECCHHHHHHHHHHHHHEEEEEEECCCCCHHHH
IQQLRAAGIVVSAGHSNASYQEARRGFAAGMRFATHLYNAMPAISGRAPGLMGAIFDTPE
HHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCH
VYTGIIADGHHVAWPNIRMAKKLKGDHLVLVTDATAPAGSNIDSFIFAGKTVYYRNGLVV
HHEEEEECCCEEECCCCHHHHHCCCCEEEEEECCCCCCCCCCCHHEEECCEEEEECCEEE
DENGTLSGSALTMIGAVQNSVEHVGIALDEALRMASLYPARAIGVAQRLGSIEPGKVANL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEE
TAFTRDFQVTTTIVNGETVYQRGG
EEEEECEEEEEEEECCCEEEECCC
>Mature Secondary Structure
MYALTHCRIYTGHDILDDHAVVIANGLIEKICPESALAPDITTRDLGGAILAPGFIDVQL
CCEEEEEEEEECCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEE
NGCGGVQFNDSEEAVSEQTLEIMQRTNERAGCTSYLPTLITCSDAMMQRGITVMHSYLRR
CCCCCCEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HRNQALGLHIEGPYISPEKKGTHNPRYIRRPDRAMLDFICSHAEAIVKVTMAPEMSDDAA
HCCCEEEEEEECCEECCCCCCCCCCCCEECCHHHHHHHHHHHHHEEEEEEECCCCCHHHH
IQQLRAAGIVVSAGHSNASYQEARRGFAAGMRFATHLYNAMPAISGRAPGLMGAIFDTPE
HHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCH
VYTGIIADGHHVAWPNIRMAKKLKGDHLVLVTDATAPAGSNIDSFIFAGKTVYYRNGLVV
HHEEEEECCCEEECCCCHHHHHCCCCEEEEEECCCCCCCCCCCHHEEECCEEEEECCEEE
DENGTLSGSALTMIGAVQNSVEHVGIALDEALRMASLYPARAIGVAQRLGSIEPGKVANL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEE
TAFTRDFQVTTTIVNGETVYQRGG
EEEEECEEEEEEEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]