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The map label for this gene is glnS

Identifier: 238920787

GI number: 238920787

Start: 2797621

End: 2799288

Strand: Reverse

Name: glnS

Synonym: NT01EI_2906

Alternate gene names: 238920787

Gene position: 2799288-2797621 (Counterclockwise)

Preceding gene: 238920788

Following gene: 238920786

Centisome position: 73.43

GC content: 58.69

Gene sequence:

>1668_bases
ATGAGTGAGGCTGAAGCCCGCCCAACCAACTTTATCCGTCAGATCATCGATGAAGATCTGGCGTCCGGTAAACACACCAG
CGTGCATACCCGTTTCCCGCCGGAGCCAAACGGCTACCTGCACATTGGCCACGCCAAGTCCATCTGCCTGAATTTCGGCA
TCGCCAGAGACTATCAAGGGCTGTGCAACCTGCGCTTCGATGATACCAACCCGGTAAAGGAAGACATCGAATACGTTGAG
TCCATCAAGCGCGACGTACAGTGGCTGGGCTTTGAGTGGAGCGGTGCAGTGCGCTACTCATCTGACTATTTTGACCAGCT
GCATCAGTACGCCCTGGAGCTGATTGGCAAAGGGTTGGCCTATGTGGATGAGCTGAGCGCCGAGCAGATCCGCGAATACC
GCGGTACCCTGACCTCGCCCGGGAAGAATAGTCCGTTCCGCGATCGCAGCGTGGAGGAGAACCTGGCGCTGTTCGAAAAA
ATGCGCTTGGGCGAGTTCGCCGAAGGCAGCGCCTGCCTGCGCGCCAGGATCGATATGGCGTCGCCGTTTATCGTGATGCG
CGATCCGGTGCTGTATCGGATTAAGTTTGCCGAACATCATCAGACCGGTAACAAGTGGTGCATCTACCCGATGTACGACT
TCACCCATTGCATCTCCGATGCGTTGGAGGGCATCACGCACTCTCTGTGCACCCTGGAGTTCCAGGACAACCGTCGCCTG
TATGACTGGGTACTGGATAATATCTCTATTCCGTGCCATCCGCGTCAGTATGAGTTTTCGCGCCTGAATCTGGAATACGC
CATCATGTCCAAGCGTAAGCTGAACCTGCTGGTGAGCGAGAAGATTGTCGAGGGCTGGGACGATCCGCGTATGCCGACCA
TTTCGGGTCTGCGCCGCCGCGGCTACAGCGCTGCTGCCGTGCGTGAGTTCTGCCGCCGTATCGGGGTGACCAAGCAGGAC
AACAACGTGGAGATGGCCGCGCTGGAGTCCTGTATCCGCGATGATCTCAATGAAAACGCTCCGCGCGCCATGGCGGTGCT
GGATCCGGTGCGTCTGGTGATCGACAATTTGGCGGCCGACAGCGTACAGTTGCTGACCATGCCGAACCACCCGAGCAAGC
CGGAGATGGGCAACCGTGAAGTGCCGTTTGCCCGCGAACTGTACATCGATCGCGCTGACTTCCGTGAAGAGGCCAACAAA
CAGTACAAGCGTCTGGTGCTGGGTAAAGAGGTGCGTCTGCGCAATGCCTACGTGATCCGTGCCGAGCGCGTGGAAAAAGA
TGCCGATGGCGAGATCACCACCATTTACTGCAGTTACGATGCGGATACCCTGAGCAAGGATCCGGCGGATGGGCGCAAGG
TTAAAGGGGTGATCCACTGGGTGTCCGCCAGCCATGCGCTGCCGGCGGAGTTCCGTCTGTACGATCGCCTGTTCAGTGTG
GCGAACCCGGGGGCGGCGGAAGATTTCCTCTCCACCATTAACCCGGAGTCCCTGGTTATTCGGCGCGGCTTCGTCGAGCC
GACGCTGGCGGCGGCGGTGCCGGAGGTGACCTACCAGTTTGAGCGTGAGGGCTATTTCTGTGCCGACATCCGTTACTCTT
CCGCCGGGCATCTGGTGTTTAACCGTACCGTCGGCCTGCGTGATACCTGGGCCAAAGCAGCGCTCTGA

Upstream 100 bases:

>100_bases
AAAAACGTCGGTATTTTACCGATAGAACGGTTGTTTCCGCCCGAGGGTTGTTAGATCATGGAATAATGAGAACGCGTTTT
TTGGCATAGAGGAACAGAAG

Downstream 100 bases:

>100_bases
GTGACGCTGCCCAGCGCAGCACGCCGATAGGCTGACAAGATAAACGCCACGGGCCACGGGTCCGTGGCGTTTTTTTTGCC
TGTATTGGCGGGATGCCCTC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSEAEARPTNFIRQIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQGLCNLRFDDTNPVKEDIEYVE
SIKRDVQWLGFEWSGAVRYSSDYFDQLHQYALELIGKGLAYVDELSAEQIREYRGTLTSPGKNSPFRDRSVEENLALFEK
MRLGEFAEGSACLRARIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRL
YDWVLDNISIPCHPRQYEFSRLNLEYAIMSKRKLNLLVSEKIVEGWDDPRMPTISGLRRRGYSAAAVREFCRRIGVTKQD
NNVEMAALESCIRDDLNENAPRAMAVLDPVRLVIDNLAADSVQLLTMPNHPSKPEMGNREVPFARELYIDRADFREEANK
QYKRLVLGKEVRLRNAYVIRAERVEKDADGEITTIYCSYDADTLSKDPADGRKVKGVIHWVSASHALPAEFRLYDRLFSV
ANPGAAEDFLSTINPESLVIRRGFVEPTLAAAVPEVTYQFEREGYFCADIRYSSAGHLVFNRTVGLRDTWAKAAL

Sequences:

>Translated_555_residues
MSEAEARPTNFIRQIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQGLCNLRFDDTNPVKEDIEYVE
SIKRDVQWLGFEWSGAVRYSSDYFDQLHQYALELIGKGLAYVDELSAEQIREYRGTLTSPGKNSPFRDRSVEENLALFEK
MRLGEFAEGSACLRARIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRL
YDWVLDNISIPCHPRQYEFSRLNLEYAIMSKRKLNLLVSEKIVEGWDDPRMPTISGLRRRGYSAAAVREFCRRIGVTKQD
NNVEMAALESCIRDDLNENAPRAMAVLDPVRLVIDNLAADSVQLLTMPNHPSKPEMGNREVPFARELYIDRADFREEANK
QYKRLVLGKEVRLRNAYVIRAERVEKDADGEITTIYCSYDADTLSKDPADGRKVKGVIHWVSASHALPAEFRLYDRLFSV
ANPGAAEDFLSTINPESLVIRRGFVEPTLAAAVPEVTYQFEREGYFCADIRYSSAGHLVFNRTVGLRDTWAKAAL
>Mature_554_residues
SEAEARPTNFIRQIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQGLCNLRFDDTNPVKEDIEYVES
IKRDVQWLGFEWSGAVRYSSDYFDQLHQYALELIGKGLAYVDELSAEQIREYRGTLTSPGKNSPFRDRSVEENLALFEKM
RLGEFAEGSACLRARIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLY
DWVLDNISIPCHPRQYEFSRLNLEYAIMSKRKLNLLVSEKIVEGWDDPRMPTISGLRRRGYSAAAVREFCRRIGVTKQDN
NVEMAALESCIRDDLNENAPRAMAVLDPVRLVIDNLAADSVQLLTMPNHPSKPEMGNREVPFARELYIDRADFREEANKQ
YKRLVLGKEVRLRNAYVIRAERVEKDADGEITTIYCSYDADTLSKDPADGRKVKGVIHWVSASHALPAEFRLYDRLFSVA
NPGAAEDFLSTINPESLVIRRGFVEPTLAAAVPEVTYQFEREGYFCADIRYSSAGHLVFNRTVGLRDTWAKAAL

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI4826960, Length=532, Percent_Identity=46.9924812030075, Blast_Score=452, Evalue=1e-127,
Organism=Homo sapiens, GI62241042, Length=519, Percent_Identity=34.2967244701349, Blast_Score=286, Evalue=3e-77,
Organism=Escherichia coli, GI1786895, Length=554, Percent_Identity=84.6570397111913, Blast_Score=1004, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=122, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17543332, Length=537, Percent_Identity=43.0167597765363, Blast_Score=426, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI17511007, Length=530, Percent_Identity=32.8301886792453, Blast_Score=256, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6324742, Length=564, Percent_Identity=42.1985815602837, Blast_Score=419, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6321192, Length=517, Percent_Identity=33.6557059961315, Blast_Score=288, Evalue=2e-78,
Organism=Drosophila melanogaster, GI17864488, Length=552, Percent_Identity=43.4782608695652, Blast_Score=444, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24649466, Length=519, Percent_Identity=34.4894026974952, Blast_Score=272, Evalue=4e-73,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYQ_EDWI9 (C5BGA4)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934302.1
- GeneID:   7960191
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2906
- OMA:   RMPTIAG
- ProtClustDB:   PRK05347
- GO:   GO:0005737
- HAMAP:   MF_00126
- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729
- Gene3D:   G3DSA:1.10.1160.10
- Gene3D:   G3DSA:2.40.240.10
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119:SF3
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR00440

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C; SSF50715 Ribosomal_L25rel

EC number: =6.1.1.18

Molecular weight: Translated: 63483; Mature: 63351

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 271-271

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAEARPTNFIRQIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQG
CCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEECCHHHHHHHCCCCCCCCC
LCNLRFDDTNPVKEDIEYVESIKRDVQWLGFEWSGAVRYSSDYFDQLHQYALELIGKGLA
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEECCEEEECHHHHHHHHHHHHHHHHCCHH
YVDELSAEQIREYRGTLTSPGKNSPFRDRSVEENLALFEKMRLGEFAEGSACLRARIDMA
HHHHHCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHEECCCC
SPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRL
CCEEEEECCEEEEEEEHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEECCCCCH
YDWVLDNISIPCHPRQYEFSRLNLEYAIMSKRKLNLLVSEKIVEGWDDPRMPTISGLRRR
HHHHHHCCCCCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHC
GYSAAAVREFCRRIGVTKQDNNVEMAALESCIRDDLNENAPRAMAVLDPVRLVIDNLAAD
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
SVQLLTMPNHPSKPEMGNREVPFARELYIDRADFREEANKQYKRLVLGKEVRLRNAYVIR
CEEEEECCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCEEEEE
AERVEKDADGEITTIYCSYDADTLSKDPADGRKVKGVIHWVSASHALPAEFRLYDRLFSV
HHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEHEEEEECCCCCCCHHHHHHHHHHHH
ANPGAAEDFLSTINPESLVIRRGFVEPTLAAAVPEVTYQFEREGYFCADIRYSSAGHLVF
CCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHCCHHHEEECCCCEEEEEEEECCCCCEEE
NRTVGLRDTWAKAAL
EECCCCCHHHHHHCC
>Mature Secondary Structure 
SEAEARPTNFIRQIIDEDLASGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQG
CCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCEEEECCHHHHHHHCCCCCCCCC
LCNLRFDDTNPVKEDIEYVESIKRDVQWLGFEWSGAVRYSSDYFDQLHQYALELIGKGLA
CEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEECCEEEECHHHHHHHHHHHHHHHHCCHH
YVDELSAEQIREYRGTLTSPGKNSPFRDRSVEENLALFEKMRLGEFAEGSACLRARIDMA
HHHHHCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHEECCCC
SPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRL
CCEEEEECCEEEEEEEHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEECCCCCH
YDWVLDNISIPCHPRQYEFSRLNLEYAIMSKRKLNLLVSEKIVEGWDDPRMPTISGLRRR
HHHHHHCCCCCCCCCCCCHHHCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHC
GYSAAAVREFCRRIGVTKQDNNVEMAALESCIRDDLNENAPRAMAVLDPVRLVIDNLAAD
CCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCC
SVQLLTMPNHPSKPEMGNREVPFARELYIDRADFREEANKQYKRLVLGKEVRLRNAYVIR
CEEEEECCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECCEEEEE
AERVEKDADGEITTIYCSYDADTLSKDPADGRKVKGVIHWVSASHALPAEFRLYDRLFSV
HHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEHEEEEECCCCCCCHHHHHHHHHHHH
ANPGAAEDFLSTINPESLVIRRGFVEPTLAAAVPEVTYQFEREGYFCADIRYSSAGHLVF
CCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHCCHHHEEECCCCEEEEEEEECCCCCEEE
NRTVGLRDTWAKAAL
EECCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA