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The map label for this gene is sucC

Identifier: 238920747

GI number: 238920747

Start: 2754082

End: 2755248

Strand: Reverse

Name: sucC

Synonym: NT01EI_2866

Alternate gene names: 238920747

Gene position: 2755248-2754082 (Counterclockwise)

Preceding gene: 238920748

Following gene: 238920746

Centisome position: 72.27

GC content: 61.7

Gene sequence:

>1167_bases
ATGAACTTACACGAATATCAGGCGAAACAGCTGTTTGCCCAGTATGGATTGCCGACGCCGGAGGGGTATGCCTGCAGTAC
GCCGTGTCAGGCGGAAGAGGCGGCCTCTAAAATCGGCAGCGGCCCCTGGGTGGTCAAGTGTCAGGTGCACGCCGGTGGGC
GGGGTAAGGCGGGCGGTGTGAAGTGCGTGGAGAGTAAAGAGGCGATCCATGCTTTTGCCGAACAGTGGCTGGGTAAGCGT
TTGGTGACCTACCAGACCGATGCCCATGGGCAGCCGGTGCGCCAGATTCTGGTGGAGGGGGCGACCGAGATTGCGCGTGA
GCTGTATCTGGGGGCGGTTATCGATCGCAGCTCCCGGCGTGTGGTGTTCATGGCATCGACTGAGGGGGGGGTGGAGATTG
AACAGGTGGCGCAAAAGACGCCCCATCTGATCCACAGGGTAGCGCTTGATCCGCTGACCGGCCCGCAGCCCTATCAGGGG
CGCGAGCTGGCGTTTAAGCTGGGGCTGAGTGGTAAGCAGGCTCAGCAGTTTGGCCAGATTTTCCTGGGACTGGCGACGCT
GTTTTTGCAGTGCGATCTGACCATGGCGGAGATCAACCCGCTGGTGATCACCCCGCAGGGGGATCTGCTGTGCCTGGACG
GTAAGCTGGACGTTGACAGCAATGCCCTGTTCCGTCAGCCGACGCTGCTCGAAATGGAGGATCCTGCGCAGAACGATGCG
CGTGAGGCGCATGCTGCACAATGGGAGCTGAACTACGTTGCGCTGGAGGGCAACATCGGCTGTATGGTGAACGGCGCCGG
TCTGGCGATGGGCACCATGGATATCGTCAAGCTGCACGGCGGCGCACCGGCTAACTTCCTGGACGTGGGCGGTGGTGCCA
CCAAGGAGAGGGTGACGGAGGCATTTAAGATCATCCTGTCCGACGAGCACGTTAGGGCGGTGCTGGTCAATATTTTCGGC
GGTATCGTGCGCTGCGACCTGATCGCCGACGGCATCATCGGTGCCGTGGCCGAGGTGGGCGTTCACGTACCGGTAGTGGT
ACGTCTGGAGGGCAACAACGCCGAGCTGGGCACCCGAATACTGGCCGACAGCGGCCTGAATATCATTGCGGCCACCAGTC
TGACGGATGCCGCGCGCCAGGTGGTTAGCGCCGTGGAGGGGAAATAA

Upstream 100 bases:

>100_bases
TGGATGTGTAACTCCGTTTGATCCGTGCTATGCCCAGGCCCGTCACGTCGGCGGGCCTGCTACTAACAATAAGAGTCAGC
CCCTATAGGGATAGAACATC

Downstream 100 bases:

>100_bases
TGTCAATACTGATCAATCACGAAACCCGGGTCATCTGTCAGGGCTTTACCGGCAGTCAGGGGACATTCCACTCCGAGCAG
GCACTGGCCTACGGTACCCG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKQLFAQYGLPTPEGYACSTPCQAEEAASKIGSGPWVVKCQVHAGGRGKAGGVKCVESKEAIHAFAEQWLGKR
LVTYQTDAHGQPVRQILVEGATEIARELYLGAVIDRSSRRVVFMASTEGGVEIEQVAQKTPHLIHRVALDPLTGPQPYQG
RELAFKLGLSGKQAQQFGQIFLGLATLFLQCDLTMAEINPLVITPQGDLLCLDGKLDVDSNALFRQPTLLEMEDPAQNDA
REAHAAQWELNYVALEGNIGCMVNGAGLAMGTMDIVKLHGGAPANFLDVGGGATKERVTEAFKIILSDEHVRAVLVNIFG
GIVRCDLIADGIIGAVAEVGVHVPVVVRLEGNNAELGTRILADSGLNIIAATSLTDAARQVVSAVEGK

Sequences:

>Translated_388_residues
MNLHEYQAKQLFAQYGLPTPEGYACSTPCQAEEAASKIGSGPWVVKCQVHAGGRGKAGGVKCVESKEAIHAFAEQWLGKR
LVTYQTDAHGQPVRQILVEGATEIARELYLGAVIDRSSRRVVFMASTEGGVEIEQVAQKTPHLIHRVALDPLTGPQPYQG
RELAFKLGLSGKQAQQFGQIFLGLATLFLQCDLTMAEINPLVITPQGDLLCLDGKLDVDSNALFRQPTLLEMEDPAQNDA
REAHAAQWELNYVALEGNIGCMVNGAGLAMGTMDIVKLHGGAPANFLDVGGGATKERVTEAFKIILSDEHVRAVLVNIFG
GIVRCDLIADGIIGAVAEVGVHVPVVVRLEGNNAELGTRILADSGLNIIAATSLTDAARQVVSAVEGK
>Mature_388_residues
MNLHEYQAKQLFAQYGLPTPEGYACSTPCQAEEAASKIGSGPWVVKCQVHAGGRGKAGGVKCVESKEAIHAFAEQWLGKR
LVTYQTDAHGQPVRQILVEGATEIARELYLGAVIDRSSRRVVFMASTEGGVEIEQVAQKTPHLIHRVALDPLTGPQPYQG
RELAFKLGLSGKQAQQFGQIFLGLATLFLQCDLTMAEINPLVITPQGDLLCLDGKLDVDSNALFRQPTLLEMEDPAQNDA
REAHAAQWELNYVALEGNIGCMVNGAGLAMGTMDIVKLHGGAPANFLDVGGGATKERVTEAFKIILSDEHVRAVLVNIFG
GIVRCDLIADGIIGAVAEVGVHVPVVVRLEGNNAELGTRILADSGLNIIAATSLTDAARQVVSAVEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=46.3104325699746, Blast_Score=347, Evalue=9e-96,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=42.2976501305483, Blast_Score=311, Evalue=5e-85,
Organism=Homo sapiens, GI294862256, Length=362, Percent_Identity=42.2651933701657, Blast_Score=295, Evalue=4e-80,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=84.2783505154639, Blast_Score=652, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539378, Length=394, Percent_Identity=42.3857868020305, Blast_Score=318, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=43.9588688946015, Blast_Score=311, Evalue=4e-85,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=40.8163265306122, Blast_Score=318, Evalue=6e-88,
Organism=Drosophila melanogaster, GI21356231, Length=394, Percent_Identity=42.1319796954315, Blast_Score=301, Evalue=5e-82,
Organism=Drosophila melanogaster, GI161078106, Length=385, Percent_Identity=42.3376623376623, Blast_Score=298, Evalue=5e-81,
Organism=Drosophila melanogaster, GI24645208, Length=385, Percent_Identity=42.3376623376623, Blast_Score=298, Evalue=5e-81,
Organism=Drosophila melanogaster, GI281361397, Length=386, Percent_Identity=42.4870466321244, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI281361395, Length=386, Percent_Identity=42.4870466321244, Blast_Score=295, Evalue=4e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_EDWI9 (C5BEM7)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934262.1
- GeneID:   7959508
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2866
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41350; Mature: 41350

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQLFAQYGLPTPEGYACSTPCQAEEAASKIGSGPWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KCVESKEAIHAFAEQWLGKRLVTYQTDAHGQPVRQILVEGATEIARELYLGAVIDRSSRR
EEEHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCE
VVFMASTEGGVEIEQVAQKTPHLIHRVALDPLTGPQPYQGRELAFKLGLSGKQAQQFGQI
EEEEECCCCCCHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
FLGLATLFLQCDLTMAEINPLVITPQGDLLCLDGKLDVDSNALFRQPTLLEMEDPAQNDA
HHHHHHHHHHCCCCHHHCCCEEECCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCHH
REAHAAQWELNYVALEGNIGCMVNGAGLAMGTMDIVKLHGGAPANFLDVGGGATKERVTE
HHHHHHEEEEEEEEEECCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDEHVRAVLVNIFGGIVRCDLIADGIIGAVAEVGVHVPVVVRLEGNNAELGTRI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEE
LADSGLNIIAATSLTDAARQVVSAVEGK
EECCCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQAKQLFAQYGLPTPEGYACSTPCQAEEAASKIGSGPWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEEEECCCCCCCCCE
KCVESKEAIHAFAEQWLGKRLVTYQTDAHGQPVRQILVEGATEIARELYLGAVIDRSSRR
EEEHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCE
VVFMASTEGGVEIEQVAQKTPHLIHRVALDPLTGPQPYQGRELAFKLGLSGKQAQQFGQI
EEEEECCCCCCHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHH
FLGLATLFLQCDLTMAEINPLVITPQGDLLCLDGKLDVDSNALFRQPTLLEMEDPAQNDA
HHHHHHHHHHCCCCHHHCCCEEECCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCHH
REAHAAQWELNYVALEGNIGCMVNGAGLAMGTMDIVKLHGGAPANFLDVGGGATKERVTE
HHHHHHEEEEEEEEEECCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDEHVRAVLVNIFGGIVRCDLIADGIIGAVAEVGVHVPVVVRLEGNNAELGTRI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEE
LADSGLNIIAATSLTDAARQVVSAVEGK
EECCCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA