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The map label for this gene is citT [C]

Identifier: 238920732

GI number: 238920732

Start: 2737004

End: 2738380

Strand: Reverse

Name: citT [C]

Synonym: NT01EI_2845

Alternate gene names: 238920732

Gene position: 2738380-2737004 (Counterclockwise)

Preceding gene: 238920734

Following gene: 238920725

Centisome position: 71.83

GC content: 61.58

Gene sequence:

>1377_bases
ATGGAAGCAACCCCGTTGACCGCTGCAGTGACCAGCCCACCGTCGCAGCGGGGCTTGGTGATTATCGCGTTCGATATCGC
GCTGCTGCTGCTGCTTAATACCCTGCCTTTTGAGGCAAAAGCCAATACCGGCCTGGCGCTGACCGTGTTTATCGGCGTGC
TGTGGCTGACAGAGGCGGTACATGTAACCATCACGGCGCTGCTGGTGCCGCTGCTGGCGATCGGCTTTGGACTATTGGAC
GCCGGCGGCGCGCTGAAGTCTTTTTCTAACCCAACCATCTTTCTGTTTTTCGGCGGCTTTGTGTTGGCGACGGCGCTGCA
CGTGCAGGGGCTGGATCGCCTGATCGCCAACCGGCTGCTGCTTTTGGCCGGTGGGCGCATGGGGACGGCGGTATTGATGC
TGTTCAGCGTCACCGCAATGCTCTCTATGTGGATCAGCAATACGGCAACGGCGGCGATGATGCTGCCGCTGGCGCTGGGG
ATCCTGGCTAACCTGGATCCGGTACGTGAGCGTAATACCTATGTGTTTCTGCTGCTGGGGATCGCCTACAGCGCCAGCAT
CGGTGGCCTCGGTACCCTGGTGGGCAGTCCGCCCAACGCTATCGCCGCAGCGCAGTTGGGGATCGACTTCCTCACCTGGA
TGAAGTTTGGCATCCCGGTGATGGTGGTGATGATGCCACTGATGATGGGGCTGCTTTACCTGATACTGCGCCCTAACCTG
ACGCACCGGGTGACGCTGCAGGTGGAGACCCTGGAGTGGACCTTGCCGCGCCTGATTGCGCTGGCTATCTTTGGGCTTAC
GGTCTCCGGCTGGATCTTCAGCACCCAGCTCAGTGCCCTGCTGGGCGGGATCAAGCAGTTTGATACCCTGGTTGCGGTGT
CGGCCGCGGTGCTGATCGGCGCCACCGGGGTGGCCAGCTGGGAGCAGATCCAGCGCAATACGGAGTGGGGGGTGCTGATG
TTGTTCGGTGGCGGACTGACCCTGAGCCTGATCCTGGAGGACTCCGGCGCCAGCACTATCTTGGCGCGCGGTATGGCCGA
TATCTTTGGGCAGAGCCACTGGTTTATCATTCTGCTGGTGGTGGCGGCATTCATCATTTTTCTGACCGAGTTTACCAGCA
ATACCGCCAGCGCCGCGCTGCTGGTGCCGGTATTCGCAACCCTCGCCAAGGCGCTGGGCATGCCGGAGAGCCTGCTGACG
TTGGTGATCGGGATTGGCGCCTCCTGCGCCTTCATGCTGCCCGTGGCCACGCCGCCGAATGCCATCGTGTTCGGCTCGGG
CTATATCCGCCAGCGGGAGATGGTGCGGGTCGGCTTTTGGCTCAACCTGGTCAGCATCGTTGCACTCAGCCTGTTCGCCT
GGTTCTTCTGGCGCTGA

Upstream 100 bases:

>100_bases
TCCGTGCCACCGGCGTCCGACATCGATTCCTCTCGGTATCGGGCACCGTCGGCGCCGATAGGGGTAAGTATGGCATCGAT
TCAGGATAGAGAGGTTCTAC

Downstream 100 bases:

>100_bases
GGTGCCCCGAGCCTGCCATCACCGCGCGGACGGATGTGCCGTCGCGCGCGGTGGTAGCTCTCAGCGCAGTCTGAACTGAT
AGTGGGTAAAAGCCCGGTAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MEATPLTAAVTSPPSQRGLVIIAFDIALLLLLNTLPFEAKANTGLALTVFIGVLWLTEAVHVTITALLVPLLAIGFGLLD
AGGALKSFSNPTIFLFFGGFVLATALHVQGLDRLIANRLLLLAGGRMGTAVLMLFSVTAMLSMWISNTATAAMMLPLALG
ILANLDPVRERNTYVFLLLGIAYSASIGGLGTLVGSPPNAIAAAQLGIDFLTWMKFGIPVMVVMMPLMMGLLYLILRPNL
THRVTLQVETLEWTLPRLIALAIFGLTVSGWIFSTQLSALLGGIKQFDTLVAVSAAVLIGATGVASWEQIQRNTEWGVLM
LFGGGLTLSLILEDSGASTILARGMADIFGQSHWFIILLVVAAFIIFLTEFTSNTASAALLVPVFATLAKALGMPESLLT
LVIGIGASCAFMLPVATPPNAIVFGSGYIRQREMVRVGFWLNLVSIVALSLFAWFFWR

Sequences:

>Translated_458_residues
MEATPLTAAVTSPPSQRGLVIIAFDIALLLLLNTLPFEAKANTGLALTVFIGVLWLTEAVHVTITALLVPLLAIGFGLLD
AGGALKSFSNPTIFLFFGGFVLATALHVQGLDRLIANRLLLLAGGRMGTAVLMLFSVTAMLSMWISNTATAAMMLPLALG
ILANLDPVRERNTYVFLLLGIAYSASIGGLGTLVGSPPNAIAAAQLGIDFLTWMKFGIPVMVVMMPLMMGLLYLILRPNL
THRVTLQVETLEWTLPRLIALAIFGLTVSGWIFSTQLSALLGGIKQFDTLVAVSAAVLIGATGVASWEQIQRNTEWGVLM
LFGGGLTLSLILEDSGASTILARGMADIFGQSHWFIILLVVAAFIIFLTEFTSNTASAALLVPVFATLAKALGMPESLLT
LVIGIGASCAFMLPVATPPNAIVFGSGYIRQREMVRVGFWLNLVSIVALSLFAWFFWR
>Mature_458_residues
MEATPLTAAVTSPPSQRGLVIIAFDIALLLLLNTLPFEAKANTGLALTVFIGVLWLTEAVHVTITALLVPLLAIGFGLLD
AGGALKSFSNPTIFLFFGGFVLATALHVQGLDRLIANRLLLLAGGRMGTAVLMLFSVTAMLSMWISNTATAAMMLPLALG
ILANLDPVRERNTYVFLLLGIAYSASIGGLGTLVGSPPNAIAAAQLGIDFLTWMKFGIPVMVVMMPLMMGLLYLILRPNL
THRVTLQVETLEWTLPRLIALAIFGLTVSGWIFSTQLSALLGGIKQFDTLVAVSAAVLIGATGVASWEQIQRNTEWGVLM
LFGGGLTLSLILEDSGASTILARGMADIFGQSHWFIILLVVAAFIIFLTEFTSNTASAALLVPVFATLAKALGMPESLLT
LVIGIGASCAFMLPVATPPNAIVFGSGYIRQREMVRVGFWLNLVSIVALSLFAWFFWR

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI301069349, Length=488, Percent_Identity=28.6885245901639, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI29171306, Length=503, Percent_Identity=27.4353876739563, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI219802232, Length=442, Percent_Identity=26.2443438914027, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI31377715, Length=279, Percent_Identity=29.3906810035842, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI301069346, Length=146, Percent_Identity=36.986301369863, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI58761541, Length=146, Percent_Identity=36.986301369863, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI301069353, Length=146, Percent_Identity=36.986301369863, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4506979, Length=233, Percent_Identity=30.0429184549356, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI31795546, Length=331, Percent_Identity=25.6797583081571, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI225637552, Length=157, Percent_Identity=35.6687898089172, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI225637549, Length=157, Percent_Identity=35.6687898089172, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI19923838, Length=333, Percent_Identity=26.4264264264264, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1786829, Length=409, Percent_Identity=27.6283618581907, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71988385, Length=443, Percent_Identity=30.2483069977427, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI32565804, Length=438, Percent_Identity=29.9086757990868, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17551790, Length=507, Percent_Identity=24.4575936883629, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71989118, Length=496, Percent_Identity=26.2096774193548, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32564681, Length=486, Percent_Identity=24.2798353909465, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322263, Length=403, Percent_Identity=26.0545905707196, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6319885, Length=424, Percent_Identity=27.5943396226415, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324340, Length=412, Percent_Identity=24.5145631067961, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI281362114, Length=225, Percent_Identity=27.5555555555556, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281362112, Length=225, Percent_Identity=27.5555555555556, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281362116, Length=225, Percent_Identity=27.5555555555556, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45551633, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI281366409, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17737623, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24666468, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI78706796, Length=227, Percent_Identity=29.5154185022026, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI78706798, Length=227, Percent_Identity=29.5154185022026, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 48811; Mature: 48811

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS01271 NA_SULFATE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATPLTAAVTSPPSQRGLVIIAFDIALLLLLNTLPFEAKANTGLALTVFIGVLWLTEAV
CCCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
HVTITALLVPLLAIGFGLLDAGGALKSFSNPTIFLFFGGFVLATALHVQGLDRLIANRLL
HHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LLAGGRMGTAVLMLFSVTAMLSMWISNTATAAMMLPLALGILANLDPVRERNTYVFLLLG
HEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IAYSASIGGLGTLVGSPPNAIAAAQLGIDFLTWMKFGIPVMVVMMPLMMGLLYLILRPNL
HHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC
THRVTLQVETLEWTLPRLIALAIFGLTVSGWIFSTQLSALLGGIKQFDTLVAVSAAVLIG
CEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATGVASWEQIQRNTEWGVLMLFGGGLTLSLILEDSGASTILARGMADIFGQSHWFIILLV
CCCCCHHHHHHCCCCCCEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHH
VAAFIIFLTEFTSNTASAALLVPVFATLAKALGMPESLLTLVIGIGASCAFMLPVATPPN
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCC
AIVFGSGYIRQREMVRVGFWLNLVSIVALSLFAWFFWR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEATPLTAAVTSPPSQRGLVIIAFDIALLLLLNTLPFEAKANTGLALTVFIGVLWLTEAV
CCCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
HVTITALLVPLLAIGFGLLDAGGALKSFSNPTIFLFFGGFVLATALHVQGLDRLIANRLL
HHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
LLAGGRMGTAVLMLFSVTAMLSMWISNTATAAMMLPLALGILANLDPVRERNTYVFLLLG
HEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
IAYSASIGGLGTLVGSPPNAIAAAQLGIDFLTWMKFGIPVMVVMMPLMMGLLYLILRPNL
HHHHCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC
THRVTLQVETLEWTLPRLIALAIFGLTVSGWIFSTQLSALLGGIKQFDTLVAVSAAVLIG
CEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ATGVASWEQIQRNTEWGVLMLFGGGLTLSLILEDSGASTILARGMADIFGQSHWFIILLV
CCCCCHHHHHHCCCCCCEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHH
VAAFIIFLTEFTSNTASAALLVPVFATLAKALGMPESLLTLVIGIGASCAFMLPVATPPN
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCC
AIVFGSGYIRQREMVRVGFWLNLVSIVALSLFAWFFWR
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]