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The map label for this gene is eco [H]

Identifier: 238920684

GI number: 238920684

Start: 2687767

End: 2688276

Strand: Reverse

Name: eco [H]

Synonym: NT01EI_2797

Alternate gene names: 238920684

Gene position: 2688276-2687767 (Counterclockwise)

Preceding gene: 238920685

Following gene: 238920680

Centisome position: 70.52

GC content: 58.82

Gene sequence:

>510_bases
TTGATGATGAAGACATTCTCTATGATGATGGCGGGCATGATGTTAGCTGCTTCTTCTGTGAGCGCCTGGGCCGACCCGGT
GGATCTCAGCCGCCAGCCGCTGGATAAGGTGGCGCCCTATCTTCAGGCAGAGCAGGGCATGACGCGTCAGGTTATCTATC
TGCCTCCGCGCGCCGACGAGGAGTCGCTGCGGGTTGAGCTGTTGATCGGTAAAACGCTGCAGGTCGACTGTAACCGTCAG
CGCCTGATGGGGCAGTTGGAAAGTAAGACTCTACAGGGTTGGGGATACGACTACCTGGTGATGGATAAGGTCAGCGGACC
AATGGGAACGCTGATGGCCTGCCCGGACAGTCAGCGTCATCCGGCGTTTGTGACGGTTCACTTAGGCGACAGTGCGCTGC
AGCGCTACAACAGCAAGCTACCGCTGGTGGTCTATGTGCCGCAGGGGGTGCAGGTGAAGTACCGCGTCTGGCAGGCCCAG
CCGACGGTGATGGACGCGCAGATCAAATAA

Upstream 100 bases:

>100_bases
GCGATGCTCTGTTTTGTCGGAATACACCTATGGGGAGAGTGAACGCCAGTGTGTTAGGCTGTTACCCGTTTGGCGCATCG
CGCACAGGATAAATAAGGAT

Downstream 100 bases:

>100_bases
CGTGTGGTGGTGGGCCGCTGGAGCCCGCTGCGATGGGGCGCCCGGGCGCCCGGGCGTCAGGCGGGTGATAGCGCGACGCA
GCGATCCCCGTCCGCTTGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MMMKTFSMMMAGMMLAASSVSAWADPVDLSRQPLDKVAPYLQAEQGMTRQVIYLPPRADEESLRVELLIGKTLQVDCNRQ
RLMGQLESKTLQGWGYDYLVMDKVSGPMGTLMACPDSQRHPAFVTVHLGDSALQRYNSKLPLVVYVPQGVQVKYRVWQAQ
PTVMDAQIK

Sequences:

>Translated_169_residues
MMMKTFSMMMAGMMLAASSVSAWADPVDLSRQPLDKVAPYLQAEQGMTRQVIYLPPRADEESLRVELLIGKTLQVDCNRQ
RLMGQLESKTLQGWGYDYLVMDKVSGPMGTLMACPDSQRHPAFVTVHLGDSALQRYNSKLPLVVYVPQGVQVKYRVWQAQ
PTVMDAQIK
>Mature_169_residues
MMMKTFSMMMAGMMLAASSVSAWADPVDLSRQPLDKVAPYLQAEQGMTRQVIYLPPRADEESLRVELLIGKTLQVDCNRQ
RLMGQLESKTLQGWGYDYLVMDKVSGPMGTLMACPDSQRHPAFVTVHLGDSALQRYNSKLPLVVYVPQGVQVKYRVWQAQ
PTVMDAQIK

Specific function: General inhibitor of pancreatic serine proteases:inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=163, Percent_Identity=56.441717791411, Blast_Score=199, Evalue=8e-53,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 18999; Mature: 18999

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
8.3 %Met     (Translated Protein)
9.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
8.3 %Met     (Mature Protein)
9.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMMKTFSMMMAGMMLAASSVSAWADPVDLSRQPLDKVAPYLQAEQGMTRQVIYLPPRADE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCC
ESLRVELLIGKTLQVDCNRQRLMGQLESKTLQGWGYDYLVMDKVSGPMGTLMACPDSQRH
CCEEEEEEECCEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCCCC
PAFVTVHLGDSALQRYNSKLPLVVYVPQGVQVKYRVWQAQPTVMDAQIK
CEEEEEEECHHHHHHHCCCCCEEEECCCCCEEEEEEEECCCCEEEEECC
>Mature Secondary Structure
MMMKTFSMMMAGMMLAASSVSAWADPVDLSRQPLDKVAPYLQAEQGMTRQVIYLPPRADE
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCC
ESLRVELLIGKTLQVDCNRQRLMGQLESKTLQGWGYDYLVMDKVSGPMGTLMACPDSQRH
CCEEEEEEECCEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCCCC
PAFVTVHLGDSALQRYNSKLPLVVYVPQGVQVKYRVWQAQPTVMDAQIK
CEEEEEEECHHHHHHHCCCCCEEEECCCCCEEEEEEEECCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA