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The map label for this gene is leuE [H]

Identifier: 238920682

GI number: 238920682

Start: 2686507

End: 2687145

Strand: Direct

Name: leuE [H]

Synonym: NT01EI_2795

Alternate gene names: 238920682

Gene position: 2686507-2687145 (Clockwise)

Preceding gene: 238920681

Following gene: 238920683

Centisome position: 70.47

GC content: 52.9

Gene sequence:

>639_bases
GTGTTAGAAAGCTTTGGAGTGCTTAACATATGGACATATATACTAGGCACGATATTCATCATTCTGGTTCCAGGTCCCAA
TACACTGTTCGTCCTCAAGACCGGAATCACCGGCGGTATCCGTGAAGGATATAAGGCCACCAGCGCAGTGTTGATAGGCG
ATGGTGCCCTGATTTTCCTGGCCTATTTAGGGATTGCTTCGCTGATCCGCTCCTCCCCGTTTTTGTTTAATCTAATCAAA
ATGCTCGGGGCGCTCTACCTGCTCTATCTGGGGATAAAAATCCTCTATTCAGCCCTGCGCCATACCCCGCGTCAGAGCAA
CGAGGAGCGCGTCGAGGTCAGCCATACTTTCCGTAAGGCGCTGACGCTAAGCCTGACCAACCCTAAATCGATACTGTTCT
ATGTCTCCTTCTTCGTGCAGTTTATCGACCTAAACTATGCTCACACCGGGCTCTCGTTTTTAATCCTGGCGACCATCCTG
GAGTGTATCAGCATCTGCTACATGACATTTTTGATCTTCTCCGGCGCCGCGCTGGCCCGCTTTCTGGGACAGAAGCAGCG
CCTGGCCCGCCTGGGGAACTCCATGGTCGGCCTGATGTTCCTCGGCTTCGCCAGTAAACTGGCCAGCGCCACCGCCTAG

Upstream 100 bases:

>100_bases
TGCATCTTGCCTCTGCCATTCAACGTATAAAGTGTGTAGAATAATCGAACATCATCAAGTTGATAATTAAGAATAATTAA
CTAATTATAGCGAGGTTTAT

Downstream 100 bases:

>100_bases
TCACTGCCCGGCGGGGGTCGACCTTCGCCGGCGTTCGCCACATTCTCTCCGTATTGCCGCGATTATTACGCCTGGAAATA
TCTGGCTGACGTTTCTTTAC

Product: leucine export protein LeuE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MLESFGVLNIWTYILGTIFIILVPGPNTLFVLKTGITGGIREGYKATSAVLIGDGALIFLAYLGIASLIRSSPFLFNLIK
MLGALYLLYLGIKILYSALRHTPRQSNEERVEVSHTFRKALTLSLTNPKSILFYVSFFVQFIDLNYAHTGLSFLILATIL
ECISICYMTFLIFSGAALARFLGQKQRLARLGNSMVGLMFLGFASKLASATA

Sequences:

>Translated_212_residues
MLESFGVLNIWTYILGTIFIILVPGPNTLFVLKTGITGGIREGYKATSAVLIGDGALIFLAYLGIASLIRSSPFLFNLIK
MLGALYLLYLGIKILYSALRHTPRQSNEERVEVSHTFRKALTLSLTNPKSILFYVSFFVQFIDLNYAHTGLSFLILATIL
ECISICYMTFLIFSGAALARFLGQKQRLARLGNSMVGLMFLGFASKLASATA
>Mature_212_residues
MLESFGVLNIWTYILGTIFIILVPGPNTLFVLKTGITGGIREGYKATSAVLIGDGALIFLAYLGIASLIRSSPFLFNLIK
MLGALYLLYLGIKILYSALRHTPRQSNEERVEVSHTFRKALTLSLTNPKSILFYVSFFVQFIDLNYAHTGLSFLILATIL
ECISICYMTFLIFSGAALARFLGQKQRLARLGNSMVGLMFLGFASKLASATA

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=209, Percent_Identity=55.5023923444976, Blast_Score=252, Evalue=1e-68,
Organism=Escherichia coli, GI48994978, Length=196, Percent_Identity=28.0612244897959, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786522, Length=184, Percent_Identity=29.8913043478261, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994979, Length=206, Percent_Identity=27.1844660194175, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 23339; Mature: 23339

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESFGVLNIWTYILGTIFIILVPGPNTLFVLKTGITGGIREGYKATSAVLIGDGALIFL
CCCCCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCHHHCHHHHHEEEECCHHHHHH
AYLGIASLIRSSPFLFNLIKMLGALYLLYLGIKILYSALRHTPRQSNEERVEVSHTFRKA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LTLSLTNPKSILFYVSFFVQFIDLNYAHTGLSFLILATILECISICYMTFLIFSGAALAR
HHHEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGQKQRLARLGNSMVGLMFLGFASKLASATA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLESFGVLNIWTYILGTIFIILVPGPNTLFVLKTGITGGIREGYKATSAVLIGDGALIFL
CCCCCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCHHHCHHHHHEEEECCHHHHHH
AYLGIASLIRSSPFLFNLIKMLGALYLLYLGIKILYSALRHTPRQSNEERVEVSHTFRKA
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
LTLSLTNPKSILFYVSFFVQFIDLNYAHTGLSFLILATILECISICYMTFLIFSGAALAR
HHHEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGQKQRLARLGNSMVGLMFLGFASKLASATA
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]