BacMap

Definition	Edwardsiella ictaluri 93-146 chromosome, complete genome.
Accession	NC_012779
Length	3,812,315

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The map label for this gene is ccmA [H]

Identifier: 238920657

GI number: 238920657

Start: 2666663

End: 2667286

Strand: Reverse

Name: ccmA [H]

Synonym: NT01EI_2769

Alternate gene names: 238920657

Gene position: 2667286-2666663 (Counterclockwise)

Preceding gene: 238920658

Following gene: 238920656

Centisome position: 69.96

GC content: 63.3

Gene sequence:

>624_bases
ATGTTGACCATTTCCCGGCTGGGATGCCGCCGCGATGAGCGTGTGCTGTTTGACGATCTGGACTTTCGGGTACAGGCGGG
GGAGATCATTCAGATTGAGGGGCCTAACGGGGCGGGAAAGACCACGCTGTTACGAATGATGGCGGGGCTGGCCTTACCGG
ATCGCGGCGAAGTCCTGTGGCAGGGGCACTCCATCCGTCGCCAGCGTGAGATATATCAGCAGAATTTGCTGTACTTAGGG
CATCACCCCGGCGTCAAAAGCGTGATGACGGCGTTTGAGAACCTGGCGTTTTACTGCCGGGTACTGGGGCGGGCCGATGA
GGCCCCGATTTGGGATGCGCTGGCGCAGGTCGAGCTGGTTGGCTTTGAAGATGTTCCTGTCGCCCAGCTGTCGGCGGGGC
AGCAGCGCCGGGTGGCACTGGCGCGCCTGTGGCTGAGCCAGGCGCCGCTGTGGATCCTGGATGAGCCGCTGACGGCGATC
GATAAACTCGGGGTGGCCCGGCTGATCGGGCTGTTTGAGCGCCACTGTGCGGCCGGGGGCGCTATCGTGCTGACGACCCA
TCAGGAGCTGAATTATCCCGCCATGCGTCGCCTGCGTCTGCGCGGTGAGGAGAGGGCGGTATGA

Upstream 100 bases:

>100_bases
TTTTACCCCAAATGAGTTAGGTGGAGGGAGTTTACGGGGGTTCGGGGGATGAAGAGCTTATGCTATTATGCAGCGATTAA
AATCAGGACAGAATCTATCC

Downstream 100 bases:

>100_bases
TACTGGCGGTCATTCGGCGTGAGCTCCGCATCGCGCTGCGCAGCGGAGCGGAAATTATCAATCCGCTATGGTTTTTTCTG
ATTGTGGTCACGCTGTTCCC

Product: heme ABC exporter, ATP-binding protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MLTISRLGCRRDERVLFDDLDFRVQAGEIIQIEGPNGAGKTTLLRMMAGLALPDRGEVLWQGHSIRRQREIYQQNLLYLG
HHPGVKSVMTAFENLAFYCRVLGRADEAPIWDALAQVELVGFEDVPVAQLSAGQQRRVALARLWLSQAPLWILDEPLTAI
DKLGVARLIGLFERHCAAGGAIVLTTHQELNYPAMRRLRLRGEERAV

Sequences:

>Translated_207_residues
MLTISRLGCRRDERVLFDDLDFRVQAGEIIQIEGPNGAGKTTLLRMMAGLALPDRGEVLWQGHSIRRQREIYQQNLLYLG
HHPGVKSVMTAFENLAFYCRVLGRADEAPIWDALAQVELVGFEDVPVAQLSAGQQRRVALARLWLSQAPLWILDEPLTAI
DKLGVARLIGLFERHCAAGGAIVLTTHQELNYPAMRRLRLRGEERAV
>Mature_207_residues
MLTISRLGCRRDERVLFDDLDFRVQAGEIIQIEGPNGAGKTTLLRMMAGLALPDRGEVLWQGHSIRRQREIYQQNLLYLG
HHPGVKSVMTAFENLAFYCRVLGRADEAPIWDALAQVELVGFEDVPVAQLSAGQQRRVALARLWLSQAPLWILDEPLTAI
DKLGVARLIGLFERHCAAGGAIVLTTHQELNYPAMRRLRLRGEERAV

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI47078218, Length=184, Percent_Identity=32.6086956521739, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI45446740, Length=184, Percent_Identity=32.6086956521739, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI27436953, Length=186, Percent_Identity=32.258064516129, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI21536376, Length=187, Percent_Identity=29.9465240641711, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI105990541, Length=178, Percent_Identity=28.6516853932584, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI153792144, Length=162, Percent_Identity=30.8641975308642, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI116734710, Length=187, Percent_Identity=27.807486631016, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI150417984, Length=175, Percent_Identity=29.1428571428571, Blast_Score=70, Evalue=9e-13,
Organism=Homo sapiens, GI27477115, Length=159, Percent_Identity=28.3018867924528, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI27881501, Length=177, Percent_Identity=24.2937853107345, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI30795238, Length=177, Percent_Identity=24.2937853107345, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082064, Length=202, Percent_Identity=57.9207920792079, Blast_Score=208, Evalue=2e-55,
Organism=Escherichia coli, GI87081709, Length=155, Percent_Identity=35.4838709677419, Blast_Score=97, Evalue=5e-22,
Organism=Escherichia coli, GI1788761, Length=153, Percent_Identity=33.9869281045752, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1787370, Length=166, Percent_Identity=34.9397590361446, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87081782, Length=173, Percent_Identity=29.4797687861272, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1789873, Length=189, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI87081791, Length=196, Percent_Identity=31.6326530612245, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1786698, Length=198, Percent_Identity=28.2828282828283, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1788225, Length=183, Percent_Identity=31.1475409836066, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1788165, Length=162, Percent_Identity=30.8641975308642, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789586, Length=196, Percent_Identity=31.1224489795918, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI87081834, Length=199, Percent_Identity=29.6482412060301, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790544, Length=215, Percent_Identity=26.046511627907, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790467, Length=183, Percent_Identity=28.4153005464481, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788897, Length=194, Percent_Identity=29.3814432989691, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787029, Length=188, Percent_Identity=29.2553191489362, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786563, Length=194, Percent_Identity=29.3814432989691, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1789032, Length=153, Percent_Identity=31.3725490196078, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI48994943, Length=168, Percent_Identity=25, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789593, Length=195, Percent_Identity=25.1282051282051, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787089, Length=181, Percent_Identity=27.0718232044199, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788053, Length=172, Percent_Identity=31.9767441860465, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786319, Length=175, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=4e-11,
Organism=Escherichia coli, GI1787712, Length=183, Percent_Identity=28.4153005464481, Blast_Score=61, Evalue=4e-11,
Organism=Escherichia coli, GI48994997, Length=185, Percent_Identity=27.027027027027, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1789891, Length=192, Percent_Identity=26.5625, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI87082267, Length=175, Percent_Identity=28.5714285714286, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI48995001, Length=186, Percent_Identity=26.8817204301075, Blast_Score=60, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=174, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648314, Length=178, Percent_Identity=28.0898876404494, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI116007184, Length=171, Percent_Identity=28.6549707602339, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221500365, Length=171, Percent_Identity=28.6549707602339, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920532, Length=176, Percent_Identity=28.9772727272727, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24580930, Length=176, Percent_Identity=28.9772727272727, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28574533, Length=190, Percent_Identity=25.7894736842105, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI85724864, Length=186, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580555, Length=186, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85816269, Length=186, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24580553, Length=186, Percent_Identity=27.4193548387097, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666092, Length=173, Percent_Identity=29.4797687861272, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641342, Length=178, Percent_Identity=30.3370786516854, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161076682, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI161076684, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581617, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581615, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI28574744, Length=195, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574150, Length=197, Percent_Identity=25.8883248730964, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007328, Length=197, Percent_Identity=25.8883248730964, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643674, Length=189, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 23261; Mature: 23261

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTISRLGCRRDERVLFDDLDFRVQAGEIIQIEGPNGAGKTTLLRMMAGLALPDRGEVLW
CCCCCCCCCCCCCCEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEE
QGHSIRRQREIYQQNLLYLGHHPGVKSVMTAFENLAFYCRVLGRADEAPIWDALAQVELV
CCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEE
GFEDVPVAQLSAGQQRRVALARLWLSQAPLWILDEPLTAIDKLGVARLIGLFERHCAAGG
CCCCCCHHHHCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
AIVLTTHQELNYPAMRRLRLRGEERAV
EEEEEECCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLTISRLGCRRDERVLFDDLDFRVQAGEIIQIEGPNGAGKTTLLRMMAGLALPDRGEVLW
CCCCCCCCCCCCCCEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEE
QGHSIRRQREIYQQNLLYLGHHPGVKSVMTAFENLAFYCRVLGRADEAPIWDALAQVELV
CCCHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEE
GFEDVPVAQLSAGQQRRVALARLWLSQAPLWILDEPLTAIDKLGVARLIGLFERHCAAGG
CCCCCCHHHHCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCC
AIVLTTHQELNYPAMRRLRLRGEERAV
EEEEEECCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA