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The map label for this gene is fadL [H]

Identifier: 238920647

GI number: 238920647

Start: 2657652

End: 2658968

Strand: Direct

Name: fadL [H]

Synonym: NT01EI_2759

Alternate gene names: 238920647

Gene position: 2657652-2658968 (Clockwise)

Preceding gene: 238920644

Following gene: 238920659

Centisome position: 69.71

GC content: 59.76

Gene sequence:

>1317_bases
ATGCGCCAGAAAAAACTGTTTACTCGATCGGCGTTAGCCGCGGCGGTAGCACTACTCTCTTCCAACGTCAACGCAGCGGG
TTTTCAGCTCAATGAATTCTCCGCGGCCGGACTGGGCCGCGCCTTCTCCGGCGAAGGGGCCATGACCGATACACCGGCCT
CCGCCAGCCGCAACCCGGCAGTGCTGAGCACCTTCGACCGCCCGGCCATCTCCGTCGGCGGCATTTATATCGATCCCGGC
GTCGATATCACCGGAACATCACCGACCGGCCAAAGTCTGAACGCGCACAACATCGCGCCGAGCGAGCTGATCCCCAACCT
GCACTACGTGCAGCCGCTGAACGAACACTGGTCCATCGGCGCCTCCGCCACCAGCAACTACGGTCTCGCCACCGATTTTA
ACGATAATTACACCGCTGGCGCCTTTGGCGGTACCACCGATCTGATGACCGCCAACTTTAATCTGAGCACCGCCTACCGC
CTCAACCAGCAGCTGAGCTTCGGCCTAGGTATCAACGCGGTATACGCCAAGGCAAAGATCGAACGCTATGCCGGCGATCT
GCCGCAGATGCTGGCCACCAAGCTGCCGCAGCCGTATCAGTCAATGGCCATGAACATTCCCGCCAATACCCAAATCGCCC
ACCTGAAAGGCAACACCTGGGGCTATGGCTGGAACGCCGGGATCCTGTACCAGGTAGACGAGCGTAACCGCTACGCCCTG
ACCTACCGTTCAGAGGTAAAGCTCGACTTTAAAGGCGACTACAGCAGCGCCCTGCCCGCTAATCTGAACCCAATCCTGGG
CGTCATCGGTCTGCCGATGGGCAGCAGCGGTCAGGTGATCCCCGGCAAGCTGAGCATGACCCTGCCGGCGATGCTGGAGG
TCTCCGGTTATAACCGCGTGGCATCGCAGTGGGCTATCCACTACAGCCTGGCCTATACCACCTGGAGCCAGTTTAAAGAG
CTGAAGGCCACCAATGACAACAACGATACCCTATTCCAGAAAGATGAGCAGTTCCACGATGCTTATCGTATGGCACTGGG
GGCCACCTACTACTACGACGATAGCTGGACCTTCCGCGGCGGCGTGGCCTTTGACGCGACGCCGGTACCGGCCGAGCACC
GCTCTATCTCCATTCCGGATCAGAACCGCGCCTGGCTGAGCGGCGGCTTCAGCTACGCCTTTAACCGCGATCTCTCCGTG
GACGTTGGCGCCTCCTATATGCACGGCTCCCACGTTAACTTCAAGGAAGGCCCCTATACCTTCCGCTCCGTCGGTAAGGC
CTGGCTGTACGGTGCCAACCTGAACTACGCTTTCTGA

Upstream 100 bases:

>100_bases
ACACTGGTCTGATTTGTTAGGCCGCTGCTCCCCCCTACAATCCGTGCTCCTTGTTACGACGTGTAACATTATTTAAAAAG
AGTTCTACGAGGCTTCGGAT

Downstream 100 bases:

>100_bases
TAGTGACGCTACCGGAAACCGAGCGCCCCTGTGGGGGCGTTTTTTTTATCTCCACCCCCACGACCACCCCCAAAGCAGTA
CCGGCAATGATGGCGATAGA

Product: long-chain fatty acid outer membrane transporter

Products: NA

Alternate protein names: Outer membrane fadL protein; Outer membrane flp protein [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MRQKKLFTRSALAAAVALLSSNVNAAGFQLNEFSAAGLGRAFSGEGAMTDTPASASRNPAVLSTFDRPAISVGGIYIDPG
VDITGTSPTGQSLNAHNIAPSELIPNLHYVQPLNEHWSIGASATSNYGLATDFNDNYTAGAFGGTTDLMTANFNLSTAYR
LNQQLSFGLGINAVYAKAKIERYAGDLPQMLATKLPQPYQSMAMNIPANTQIAHLKGNTWGYGWNAGILYQVDERNRYAL
TYRSEVKLDFKGDYSSALPANLNPILGVIGLPMGSSGQVIPGKLSMTLPAMLEVSGYNRVASQWAIHYSLAYTTWSQFKE
LKATNDNNDTLFQKDEQFHDAYRMALGATYYYDDSWTFRGGVAFDATPVPAEHRSISIPDQNRAWLSGGFSYAFNRDLSV
DVGASYMHGSHVNFKEGPYTFRSVGKAWLYGANLNYAF

Sequences:

>Translated_438_residues
MRQKKLFTRSALAAAVALLSSNVNAAGFQLNEFSAAGLGRAFSGEGAMTDTPASASRNPAVLSTFDRPAISVGGIYIDPG
VDITGTSPTGQSLNAHNIAPSELIPNLHYVQPLNEHWSIGASATSNYGLATDFNDNYTAGAFGGTTDLMTANFNLSTAYR
LNQQLSFGLGINAVYAKAKIERYAGDLPQMLATKLPQPYQSMAMNIPANTQIAHLKGNTWGYGWNAGILYQVDERNRYAL
TYRSEVKLDFKGDYSSALPANLNPILGVIGLPMGSSGQVIPGKLSMTLPAMLEVSGYNRVASQWAIHYSLAYTTWSQFKE
LKATNDNNDTLFQKDEQFHDAYRMALGATYYYDDSWTFRGGVAFDATPVPAEHRSISIPDQNRAWLSGGFSYAFNRDLSV
DVGASYMHGSHVNFKEGPYTFRSVGKAWLYGANLNYAF
>Mature_438_residues
MRQKKLFTRSALAAAVALLSSNVNAAGFQLNEFSAAGLGRAFSGEGAMTDTPASASRNPAVLSTFDRPAISVGGIYIDPG
VDITGTSPTGQSLNAHNIAPSELIPNLHYVQPLNEHWSIGASATSNYGLATDFNDNYTAGAFGGTTDLMTANFNLSTAYR
LNQQLSFGLGINAVYAKAKIERYAGDLPQMLATKLPQPYQSMAMNIPANTQIAHLKGNTWGYGWNAGILYQVDERNRYAL
TYRSEVKLDFKGDYSSALPANLNPILGVIGLPMGSSGQVIPGKLSMTLPAMLEVSGYNRVASQWAIHYSLAYTTWSQFKE
LKATNDNNDTLFQKDEQFHDAYRMALGATYYYDDSWTFRGGVAFDATPVPAEHRSISIPDQNRAWLSGGFSYAFNRDLSV
DVGASYMHGSHVNFKEGPYTFRSVGKAWLYGANLNYAF

Specific function: Involved in translocation of long-chain fatty acids across the outer membrane. FadL may form a specific channel [H]

COG id: COG2067

COG function: function code I; Long-chain fatty acid transport protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ompP1/fadL family [H]

Homologues:

Organism=Escherichia coli, GI145693163, Length=450, Percent_Identity=62.6666666666667, Blast_Score=573, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR001702
- InterPro:   IPR005017 [H]

Pfam domain/function: PF03349 Toluene_X [H]

EC number: NA

Molecular weight: Translated: 47657; Mature: 47657

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQKKLFTRSALAAAVALLSSNVNAAGFQLNEFSAAGLGRAFSGEGAMTDTPASASRNPA
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEECCCCCCCCCCCCCCCCCC
VLSTFDRPAISVGGIYIDPGVDITGTSPTGQSLNAHNIAPSELIPNLHYVQPLNEHWSIG
EEEECCCCCEEECCEEECCCCEEECCCCCCCCCCCCCCCHHHHCCCCCEECCCCHHCCCC
ASATSNYGLATDFNDNYTAGAFGGTTDLMTANFNLSTAYRLNQQLSFGLGINAVYAKAKI
CCCCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCEEECCCCEEEHHHHHH
ERYAGDLPQMLATKLPQPYQSMAMNIPANTQIAHLKGNTWGYGWNAGILYQVDERNRYAL
HHHHCCHHHHHHHHCCCCHHHHEECCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEE
TYRSEVKLDFKGDYSSALPANLNPILGVIGLPMGSSGQVIPGKLSMTLPAMLEVSGYNRV
EEEEEEEEEECCCCCCCCCCCCCCHHHEEECCCCCCCCCCCCEECEECCEEEEECCCHHH
ASQWAIHYSLAYTTWSQFKELKATNDNNDTLFQKDEQFHDAYRMALGATYYYDDSWTFRG
HHHEEEEEEEEEHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHCEEEEECCCEEECC
GVAFDATPVPAEHRSISIPDQNRAWLSGGFSYAFNRDLSVDVGASYMHGSHVNFKEGPYT
CEEECCCCCCCCCCEEECCCCCCCEECCCEEEEECCCCEEECCCCEECCCCCCCCCCCCH
FRSVGKAWLYGANLNYAF
HHHCCCEEEEECCCCCCC
>Mature Secondary Structure
MRQKKLFTRSALAAAVALLSSNVNAAGFQLNEFSAAGLGRAFSGEGAMTDTPASASRNPA
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEECCCCCCCCCCCCCCCCCC
VLSTFDRPAISVGGIYIDPGVDITGTSPTGQSLNAHNIAPSELIPNLHYVQPLNEHWSIG
EEEECCCCCEEECCEEECCCCEEECCCCCCCCCCCCCCCHHHHCCCCCEECCCCHHCCCC
ASATSNYGLATDFNDNYTAGAFGGTTDLMTANFNLSTAYRLNQQLSFGLGINAVYAKAKI
CCCCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCEEEEEECCCEEECCCCEEEHHHHHH
ERYAGDLPQMLATKLPQPYQSMAMNIPANTQIAHLKGNTWGYGWNAGILYQVDERNRYAL
HHHHCCHHHHHHHHCCCCHHHHEECCCCCCEEEEEECCCCCCCCCCCEEEEECCCCEEEE
TYRSEVKLDFKGDYSSALPANLNPILGVIGLPMGSSGQVIPGKLSMTLPAMLEVSGYNRV
EEEEEEEEEECCCCCCCCCCCCCCHHHEEECCCCCCCCCCCCEECEECCEEEEECCCHHH
ASQWAIHYSLAYTTWSQFKELKATNDNNDTLFQKDEQFHDAYRMALGATYYYDDSWTFRG
HHHEEEEEEEEEHHHHHHHHHHCCCCCCCCEECCHHHHHHHHHHHHCEEEEECCCEEECC
GVAFDATPVPAEHRSISIPDQNRAWLSGGFSYAFNRDLSVDVGASYMHGSHVNFKEGPYT
CEEECCCCCCCCCCEEECCCCCCCEECCCEEEEECCCCEEECCCCEECCCCCCCCCCCCH
FRSVGKAWLYGANLNYAF
HHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]