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The map label for this gene is fabG [H]

Identifier: 238920600

GI number: 238920600

Start: 2605608

End: 2606294

Strand: Direct

Name: fabG [H]

Synonym: NT01EI_2713

Alternate gene names: 238920600

Gene position: 2605608-2606294 (Clockwise)

Preceding gene: 238920599

Following gene: 238920611

Centisome position: 68.35

GC content: 65.94

Gene sequence:

>687_bases
ATGAGCCCAACCCTCTTGCGCGATAAAGTGGCGCTGGTCACCGGCGGCGCGCACGGCACCGGCGCCGCCATCGTAACAGC
CCTGGCCGACAGCGGTGCCCGCGTGGCACTGACCTACCACCATTCGGAAAGCGAGGCGCGGCGGCTGACTACCCAAATTC
GTCAGCGAGGCGGTGAGGCCATCGCCCTGCGTACCGACGCACGCAGCCCAGAAACCTGCGCCCGCGCCATCACCCGCACG
CTGGAGCTGTGGGGACAGATCGATATCCTGGTCAATCAGGCCGCCGTGACCATCTGCAAACCGTTTGATGAAATTGAACT
GCGCGAGTTTGAGCAGGTTATGGCAATCAATGTGCAGGCGGTATTTCTGACCAGCCAGCTGGCCGCCCGGCGCATGTCGG
CGGGGGGGCGAATCATTCATATCAGCGGCGCGCACCAGCCTCCCGACCACGGTGGCGCGCTCTGTGCCATGAGCCGCGCG
GCGCTGACCGCACTGACGCGCAGCATGGCGCAGGAGCTGGCACCCCAGGGCATTACGGTCAACCATCTGGTACCCGACCC
GTTTCCTTCGCCGGGCCGGGACGTAGAGGGCACGGTGCAGTCGATCGCCGAACTGGCGCTGTGGCTGGCCTCACCGGTGG
CGGGCTCCATCACCGGCAGCCAGCTCAATATGGCGGGAGAGGGTTAG

Upstream 100 bases:

>100_bases
GGCCGACGCAACTAAGACACAGCGGGCGCGATACCCCGGTTCGGCACTCCGTGCCGGTTCCGGGGCACCGGGCCCGGATA
TTTCCCACGGTGGAGCATCT

Downstream 100 bases:

>100_bases
CCTGCCACAGGCCCCTGCCAGCGTGGGAACAGATCCTGCGGCAGACAGATGTCCAGCTGATCCAGCACCCGGTTGACCGT
CTGGTCGACGAGATCCTCAA

Product: 3-oxoacyl-[acyl-carrier-protein] reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSPTLLRDKVALVTGGAHGTGAAIVTALADSGARVALTYHHSESEARRLTTQIRQRGGEAIALRTDARSPETCARAITRT
LELWGQIDILVNQAAVTICKPFDEIELREFEQVMAINVQAVFLTSQLAARRMSAGGRIIHISGAHQPPDHGGALCAMSRA
ALTALTRSMAQELAPQGITVNHLVPDPFPSPGRDVEGTVQSIAELALWLASPVAGSITGSQLNMAGEG

Sequences:

>Translated_228_residues
MSPTLLRDKVALVTGGAHGTGAAIVTALADSGARVALTYHHSESEARRLTTQIRQRGGEAIALRTDARSPETCARAITRT
LELWGQIDILVNQAAVTICKPFDEIELREFEQVMAINVQAVFLTSQLAARRMSAGGRIIHISGAHQPPDHGGALCAMSRA
ALTALTRSMAQELAPQGITVNHLVPDPFPSPGRDVEGTVQSIAELALWLASPVAGSITGSQLNMAGEG
>Mature_227_residues
SPTLLRDKVALVTGGAHGTGAAIVTALADSGARVALTYHHSESEARRLTTQIRQRGGEAIALRTDARSPETCARAITRTL
ELWGQIDILVNQAAVTICKPFDEIELREFEQVMAINVQAVFLTSQLAARRMSAGGRIIHISGAHQPPDHGGALCAMSRAA
LTALTRSMAQELAPQGITVNHLVPDPFPSPGRDVEGTVQSIAELALWLASPVAGSITGSQLNMAGEG

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=31.0756972111554, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=27.734375, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=30.1204819277108, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI32483357, Length=187, Percent_Identity=31.5508021390374, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788459, Length=240, Percent_Identity=30.4166666666667, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=30.5084745762712, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=32.2448979591837, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87082100, Length=245, Percent_Identity=30.6122448979592, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=30.4166666666667, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=27.9835390946502, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=188, Percent_Identity=31.3829787234043, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789378, Length=187, Percent_Identity=32.620320855615, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789208, Length=194, Percent_Identity=29.3814432989691, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.953125, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=24.8995983935743, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=29.2682926829268, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=189, Percent_Identity=31.7460317460317, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=190, Percent_Identity=29.4736842105263, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=191, Percent_Identity=31.9371727748691, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=189, Percent_Identity=30.1587301587302, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=194, Percent_Identity=29.3814432989691, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=191, Percent_Identity=27.7486910994764, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=192, Percent_Identity=31.7708333333333, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=28.2786885245902, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=197, Percent_Identity=29.4416243654822, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=210, Percent_Identity=28.0952380952381, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=26.0162601626016, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=193, Percent_Identity=30.5699481865285, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=181, Percent_Identity=25.9668508287293, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=245, Percent_Identity=24.0816326530612, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=193, Percent_Identity=28.4974093264249, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=28.4263959390863, Blast_Score=63, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=25.3968253968254, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=26.1780104712042, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21357041, Length=182, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI23397609, Length=182, Percent_Identity=31.3186813186813, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24643142, Length=183, Percent_Identity=32.2404371584699, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24644339, Length=181, Percent_Identity=27.6243093922652, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=27.1255060728745, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24031; Mature: 23900

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTLLRDKVALVTGGAHGTGAAIVTALADSGARVALTYHHSESEARRLTTQIRQRGGEA
CCCCHHHCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCE
IALRTDARSPETCARAITRTLELWGQIDILVNQAAVTICKPFDEIELREFEQVMAINVQA
EEEEECCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHEEECCCCHHHHHHHHHHHHHHHHH
VFLTSQLAARRMSAGGRIIHISGAHQPPDHGGALCAMSRAALTALTRSMAQELAPQGITV
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
NHLVPDPFPSPGRDVEGTVQSIAELALWLASPVAGSITGSQLNMAGEG
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
>Mature Secondary Structure 
SPTLLRDKVALVTGGAHGTGAAIVTALADSGARVALTYHHSESEARRLTTQIRQRGGEA
CCCHHHCCEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHCCCCE
IALRTDARSPETCARAITRTLELWGQIDILVNQAAVTICKPFDEIELREFEQVMAINVQA
EEEEECCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHEEECCCCHHHHHHHHHHHHHHHHH
VFLTSQLAARRMSAGGRIIHISGAHQPPDHGGALCAMSRAALTALTRSMAQELAPQGITV
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
NHLVPDPFPSPGRDVEGTVQSIAELALWLASPVAGSITGSQLNMAGEG
ECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]