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The map label for this gene is nuoC

Identifier: 238920565

GI number: 238920565

Start: 2572761

End: 2574557

Strand: Reverse

Name: nuoC

Synonym: NT01EI_2677

Alternate gene names: 238920565

Gene position: 2574557-2572761 (Counterclockwise)

Preceding gene: 238920566

Following gene: 238920564

Centisome position: 67.53

GC content: 60.32

Gene sequence:

>1797_bases
ATGACAGATTCGACGACGCACGATCGCGAGATGTCGGCGTGGCAGACCCACGACCATCTGGACGATCCGGTTATCGGGGA
ATTGCGTAACCGCTTTGGCCCGGAGGCATTCAGCGTCCAGCCGACCCGCACCGGAATGCCGGTGGTGTGGGTCAAGCGCG
AGCAGCTGCTTGAGGTGATGGCGTTCCTGAGACAGCTGCCCAAGCCCTACGTGATGCTATTTGACCTGCACGGTATGGAC
GAGCGTCTGCGTACCCATCGTCAGGGACTGCCGGCGGCGGATTTTTCCGTGTTCTACCACCTGATCTCCATCGATCGCAA
TCGCGATATTATGCTCAAGGTGGCCCTGGCCGAACAGGATCTGCACCTGCCGACGGTGACCCGTCTGTTCCCCAACGCCA
ATTGGTATGAGCGGGAAACCTTCGACCTGTTCGGCATCACCTTCGACGGTCACCCTCATCTGACGCGCCTGCTGATGCCG
CGCACCTGGCAAGGGCACCCGCTGCGCAAGGATTACCCGGCGCGTGCCACCGAATTCGATCCCTTCGAGCTGACCAGGCA
GAAGCAGGATCTGGAGATGGAGTCGCTCAAGTTCCGTCCGGAAGAGTGGGGGATGCAGCGCGGTACCGCCAACGAAGACT
TCATGTTCCTTAACCTGGGGCCGAATCATCCTTCATCCCACGGCGCCTTCCGCATCGTGCTGCAGCTGGATGGTGAGGAT
ATCGTCGACTGTGTGCCGGACATCGGCTATCACCACCGCGGTGCCGAGAAGATGGGCGAGCGCCAGTCTTGGCATAGCTA
CATTCCCTATACCGATCGCATCGAATACCTGGGCGGCTGCGTCAATGAGATGCCCTACGTGCTGGCGGTGGAGAAATTGG
CCGGGATCGAGGTGCCGGAACGGGTGAAGGTGATCCGCGTGATGCTCTCCGAGCTGTTTCGCATCAACAGCCATCTGCTG
TATATCTCCACCTTTATTCAGGACGTCGGCGCTATGACGCCGGTGTTCTTCGCCTTTACCGATCGTCAGAAGATCTATGA
CATCGTCGAAGCGGTCACCGGTTTCCGTATGCACCCGGCGTGGTTCCGCATCGGTGGCGTGGCACACGACCTGCCCAAAG
GCTGGGATCGCCTGCTGCGCGAGTTCCTTGAGTGGATGCCCAAGCGTCTGGACTCCTATGTCAAGGCGGCGCTGCACAAC
TCCATTCTGAAAGGGCGTTCCATCGGCGTGGCCGCCTATGGCGCCAAGGATGCGCTGGCCTGGGGCACCACCGGCGCCGG
TCTGCGCGCGACCGGTATCGCCTTCGACGTGCGCAAGTGGCGGCCGTACTCCGGCTATGAAAACTTTGAGTTTGAGGTGC
CGACCGCCAGCAACGGCGACTGCTATGACCGCGTGATGCTGAAGGTGGAGGAGATCCGCCAGAGCCTGCGTATTCTGCAG
CAGTGCCTGAAGAACATGCCGGAGGGGCCGTTCAAGGCGGATCACCCGCTGACCACGCCGCCGCCGAAAGAGCGCACGCT
GCAGCATATCGATACCCTGATCAACCACTTCCTGCAGGTCTCCTGGGGGCCGGTGATGCCGGCTAACGAGTCGTTCCAGA
TGGTGGAGGCGACCAAGGGCATTAACAGTTACTACCTGACCAGCGACGGCGGCACCATGAGCTATCGCACGCGTATCCGT
ACACCGAGCTATGCACACCTGCAGCAGATCCCGTCGGTGATCCGTGGCTGTCTGGTGTCCGACTTGATCGTGTACCTCGG
CAGTATTGATTTTGTTATGTCAGATGTGGACCGCTAA

Upstream 100 bases:

>100_bases
AGCGCCGCGCGGCGGGCCGTCGGGCCCGTCGTTGGAATTTAGCCCGTTTTGCCCCGCGATGCGGCGGCAAGTGTCATTCA
ATGCGTGGTGATAAAAAATT

Downstream 100 bases:

>100_bases
CCATGACAGAAAACGTATTGGATAAGGATTCGGTTTTTGTACTCAGCGACAGCGCGCGTGCTGAGATTGAGCATGAGATC
CAACACTACGAAGATCCGCG

Product: bifunctional NADH:ubiquinone oxidoreductase subunit C/D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C/D; NDH-1 subunit C/D

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MTDSTTHDREMSAWQTHDHLDDPVIGELRNRFGPEAFSVQPTRTGMPVVWVKREQLLEVMAFLRQLPKPYVMLFDLHGMD
ERLRTHRQGLPAADFSVFYHLISIDRNRDIMLKVALAEQDLHLPTVTRLFPNANWYERETFDLFGITFDGHPHLTRLLMP
RTWQGHPLRKDYPARATEFDPFELTRQKQDLEMESLKFRPEEWGMQRGTANEDFMFLNLGPNHPSSHGAFRIVLQLDGED
IVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIEVPERVKVIRVMLSELFRINSHLL
YISTFIQDVGAMTPVFFAFTDRQKIYDIVEAVTGFRMHPAWFRIGGVAHDLPKGWDRLLREFLEWMPKRLDSYVKAALHN
SILKGRSIGVAAYGAKDALAWGTTGAGLRATGIAFDVRKWRPYSGYENFEFEVPTASNGDCYDRVMLKVEEIRQSLRILQ
QCLKNMPEGPFKADHPLTTPPPKERTLQHIDTLINHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGGTMSYRTRIR
TPSYAHLQQIPSVIRGCLVSDLIVYLGSIDFVMSDVDR

Sequences:

>Translated_598_residues
MTDSTTHDREMSAWQTHDHLDDPVIGELRNRFGPEAFSVQPTRTGMPVVWVKREQLLEVMAFLRQLPKPYVMLFDLHGMD
ERLRTHRQGLPAADFSVFYHLISIDRNRDIMLKVALAEQDLHLPTVTRLFPNANWYERETFDLFGITFDGHPHLTRLLMP
RTWQGHPLRKDYPARATEFDPFELTRQKQDLEMESLKFRPEEWGMQRGTANEDFMFLNLGPNHPSSHGAFRIVLQLDGED
IVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIEVPERVKVIRVMLSELFRINSHLL
YISTFIQDVGAMTPVFFAFTDRQKIYDIVEAVTGFRMHPAWFRIGGVAHDLPKGWDRLLREFLEWMPKRLDSYVKAALHN
SILKGRSIGVAAYGAKDALAWGTTGAGLRATGIAFDVRKWRPYSGYENFEFEVPTASNGDCYDRVMLKVEEIRQSLRILQ
QCLKNMPEGPFKADHPLTTPPPKERTLQHIDTLINHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGGTMSYRTRIR
TPSYAHLQQIPSVIRGCLVSDLIVYLGSIDFVMSDVDR
>Mature_597_residues
TDSTTHDREMSAWQTHDHLDDPVIGELRNRFGPEAFSVQPTRTGMPVVWVKREQLLEVMAFLRQLPKPYVMLFDLHGMDE
RLRTHRQGLPAADFSVFYHLISIDRNRDIMLKVALAEQDLHLPTVTRLFPNANWYERETFDLFGITFDGHPHLTRLLMPR
TWQGHPLRKDYPARATEFDPFELTRQKQDLEMESLKFRPEEWGMQRGTANEDFMFLNLGPNHPSSHGAFRIVLQLDGEDI
VDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIEVPERVKVIRVMLSELFRINSHLLY
ISTFIQDVGAMTPVFFAFTDRQKIYDIVEAVTGFRMHPAWFRIGGVAHDLPKGWDRLLREFLEWMPKRLDSYVKAALHNS
ILKGRSIGVAAYGAKDALAWGTTGAGLRATGIAFDVRKWRPYSGYENFEFEVPTASNGDCYDRVMLKVEEIRQSLRILQQ
CLKNMPEGPFKADHPLTTPPPKERTLQHIDTLINHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGGTMSYRTRIRT
PSYAHLQQIPSVIRGCLVSDLIVYLGSIDFVMSDVDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the complex I 49 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758786, Length=382, Percent_Identity=40.5759162303665, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI260898743, Length=372, Percent_Identity=40.3225806451613, Blast_Score=304, Evalue=2e-82,
Organism=Homo sapiens, GI4758788, Length=126, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI145693162, Length=599, Percent_Identity=87.1452420701169, Blast_Score=1101, Evalue=0.0,
Organism=Escherichia coli, GI1789076, Length=562, Percent_Identity=26.6903914590747, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI1788832, Length=528, Percent_Identity=28.7878787878788, Blast_Score=157, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17555284, Length=396, Percent_Identity=41.4141414141414, Blast_Score=335, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI17568379, Length=398, Percent_Identity=41.9597989949749, Blast_Score=335, Evalue=6e-92,
Organism=Caenorhabditis elegans, GI71990788, Length=150, Percent_Identity=30.6666666666667, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32563621, Length=150, Percent_Identity=30.6666666666667, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221459469, Length=409, Percent_Identity=39.3643031784841, Blast_Score=332, Evalue=4e-91,
Organism=Drosophila melanogaster, GI24638644, Length=384, Percent_Identity=39.84375, Blast_Score=316, Evalue=3e-86,
Organism=Drosophila melanogaster, GI24656494, Length=126, Percent_Identity=32.5396825396825, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOCD_EDWI9 (C5B8I4)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934080.1
- GeneID:   7961703
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2677
- OMA:   PHLQQIP
- ProtClustDB:   PRK11742
- GO:   GO:0006810
- HAMAP:   MF_01359
- InterPro:   IPR010219
- InterPro:   IPR010218
- InterPro:   IPR023062
- InterPro:   IPR001135
- InterPro:   IPR001268
- InterPro:   IPR014029
- InterPro:   IPR022885
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961
- TIGRFAMs:   TIGR01962

Pfam domain/function: PF00329 Complex1_30kDa; PF00346 Complex1_49kDa

EC number: =1.6.99.5

Molecular weight: Translated: 68867; Mature: 68736

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00542 COMPLEX1_30K; PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSTTHDREMSAWQTHDHLDDPVIGELRNRFGPEAFSVQPTRTGMPVVWVKREQLLEVM
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCEECCCCCCCCCEEEECHHHHHHHH
AFLRQLPKPYVMLFDLHGMDERLRTHRQGLPAADFSVFYHLISIDRNRDIMLKVALAEQD
HHHHHCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCC
LHLPTVTRLFPNANWYERETFDLFGITFDGHPHLTRLLMPRTWQGHPLRKDYPARATEFD
CCCCHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PFELTRQKQDLEMESLKFRPEEWGMQRGTANEDFMFLNLGPNHPSSHGAFRIVLQLDGED
HHHHHHHHHCCCHHHHCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCH
IVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIEVPE
HHHHHCCCCCCCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHH
RVKVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDIVEAVTGFRMHPA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCH
WFRIGGVAHDLPKGWDRLLREFLEWMPKRLDSYVKAALHNSILKGRSIGVAAYGAKDALA
HHEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHC
WGTTGAGLRATGIAFDVRKWRPYSGYENFEFEVPTASNGDCYDRVMLKVEEIRQSLRILQ
CCCCCCCCEECCEEEEHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
QCLKNMPEGPFKADHPLTTPPPKERTLQHIDTLINHFLQVSWGPVMPANESFQMVEATKG
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
INSYYLTSDGGTMSYRTRIRTPSYAHLQQIPSVIRGCLVSDLIVYLGSIDFVMSDVDR
CCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDSTTHDREMSAWQTHDHLDDPVIGELRNRFGPEAFSVQPTRTGMPVVWVKREQLLEVM
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCEECCCCCCCCCEEEECHHHHHHHH
AFLRQLPKPYVMLFDLHGMDERLRTHRQGLPAADFSVFYHLISIDRNRDIMLKVALAEQD
HHHHHCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCC
LHLPTVTRLFPNANWYERETFDLFGITFDGHPHLTRLLMPRTWQGHPLRKDYPARATEFD
CCCCHHHHHCCCCCCCCCCCEEEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
PFELTRQKQDLEMESLKFRPEEWGMQRGTANEDFMFLNLGPNHPSSHGAFRIVLQLDGED
HHHHHHHHHCCCHHHHCCCCHHHCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCH
IVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIEVPE
HHHHHCCCCCCCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCHH
RVKVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDIVEAVTGFRMHPA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCH
WFRIGGVAHDLPKGWDRLLREFLEWMPKRLDSYVKAALHNSILKGRSIGVAAYGAKDALA
HHEECCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHC
WGTTGAGLRATGIAFDVRKWRPYSGYENFEFEVPTASNGDCYDRVMLKVEEIRQSLRILQ
CCCCCCCCEECCEEEEHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
QCLKNMPEGPFKADHPLTTPPPKERTLQHIDTLINHFLQVSWGPVMPANESFQMVEATKG
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
INSYYLTSDGGTMSYRTRIRTPSYAHLQQIPSVIRGCLVSDLIVYLGSIDFVMSDVDR
CCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA