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The map label for this gene is uxuR [H]

Identifier: 238920473

GI number: 238920473

Start: 2478722

End: 2479474

Strand: Reverse

Name: uxuR [H]

Synonym: NT01EI_2584

Alternate gene names: 238920473

Gene position: 2479474-2478722 (Counterclockwise)

Preceding gene: 238920474

Following gene: 238920472

Centisome position: 65.04

GC content: 57.9

Gene sequence:

>753_bases
ATGAGATTGTATCAGGAAGTCGGCAATACGCTGCGCGCCGCCATTGCACGCGGCGACTATTCTATCGGAGGTCGCCTGCC
GCCGGAGCGTGATATTGCCGAATATTTTGACGTAAGCCGCAGCGTCGTGCGCGAGGCGCTGATCATGCTGGAGCTGGAGC
ACCTGATCGATGTCCGTAAAGGCTCAGGGGTATACGTCGTCGCTTTGCCACAAAATGTGTCTTCCCCGCGGGTACGGAAT
CTGGATGAGAATACCTTTGGCCCCTTTGAACTGCTGCAGGCACGCCAGCTGCTGGAGAGTGAGGTCGCGGCCTTTGCCGC
GATGCAGGCGACCAAGTCCGATATTCTGAAGATGCGTCAGGCTATTGAGCAGGAGCGTCTGGCGCTAAACGCAGGGTGTG
CCGATGAGAGCGCGGATGAGCAGTTTCACTGCCTGCTGGCGCAGTCGACTCAGAATAGCGTACTGGCCGGAATGGTGGAA
GATGCCTGGCGTGCGCGCAAACATAACCCGCTGTGGGCGGGGCTGCATGGCCATACCCAGGATTTCAGCTACCGTTGGGA
CTGGCTGGAGGATCATCAAAGGATCCTTCAGGCCGTGCTGCGGCGCGACGCGCGCGACGCTAAGCAGGCGATGTGGCAGC
ATTTAGAGAATGTTAAGGCTAAACTATTGGAGATCTCCAATCCAGACGATCCGGGATTTGACGGCTATCTGTTTGACTCT
ACGCCGGTGGTGCTGGGTGACATTGCGCCATAG

Upstream 100 bases:

>100_bases
ATATAATCAAAGTCACTATAGCGGCACGTTAATAGTGACAATTGGGCTGTCCAATTGGTGCTTTTACTCTACAGATGCGG
CACAGCCAGAGGGGCTCGTC

Downstream 100 bases:

>100_bases
CGCATCGCTACACATCCACCTGCACTGCGTGTATATACTGGTGGTTGCCGTGGGGCTGCCACAGTCTGGAGAGCGGGCCT
TTCCCTTGTTACAGCCTCTG

Product: Uxu operon transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MRLYQEVGNTLRAAIARGDYSIGGRLPPERDIAEYFDVSRSVVREALIMLELEHLIDVRKGSGVYVVALPQNVSSPRVRN
LDENTFGPFELLQARQLLESEVAAFAAMQATKSDILKMRQAIEQERLALNAGCADESADEQFHCLLAQSTQNSVLAGMVE
DAWRARKHNPLWAGLHGHTQDFSYRWDWLEDHQRILQAVLRRDARDAKQAMWQHLENVKAKLLEISNPDDPGFDGYLFDS
TPVVLGDIAP

Sequences:

>Translated_250_residues
MRLYQEVGNTLRAAIARGDYSIGGRLPPERDIAEYFDVSRSVVREALIMLELEHLIDVRKGSGVYVVALPQNVSSPRVRN
LDENTFGPFELLQARQLLESEVAAFAAMQATKSDILKMRQAIEQERLALNAGCADESADEQFHCLLAQSTQNSVLAGMVE
DAWRARKHNPLWAGLHGHTQDFSYRWDWLEDHQRILQAVLRRDARDAKQAMWQHLENVKAKLLEISNPDDPGFDGYLFDS
TPVVLGDIAP
>Mature_250_residues
MRLYQEVGNTLRAAIARGDYSIGGRLPPERDIAEYFDVSRSVVREALIMLELEHLIDVRKGSGVYVVALPQNVSSPRVRN
LDENTFGPFELLQARQLLESEVAAFAAMQATKSDILKMRQAIEQERLALNAGCADESADEQFHCLLAQSTQNSVLAGMVE
DAWRARKHNPLWAGLHGHTQDFSYRWDWLEDHQRILQAVLRRDARDAKQAMWQHLENVKAKLLEISNPDDPGFDGYLFDS
TPVVLGDIAP

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=246, Percent_Identity=55.2845528455285, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI87082208, Length=250, Percent_Identity=47.2, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1786303, Length=228, Percent_Identity=28.5087719298246, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1790032, Length=238, Percent_Identity=28.9915966386555, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789353, Length=226, Percent_Identity=26.9911504424779, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789621, Length=226, Percent_Identity=26.9911504424779, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI48994955, Length=233, Percent_Identity=27.0386266094421, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787821, Length=231, Percent_Identity=27.7056277056277, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28224; Mature: 28224

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLYQEVGNTLRAAIARGDYSIGGRLPPERDIAEYFDVSRSVVREALIMLELEHLIDVRK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSGVYVVALPQNVSSPRVRNLDENTFGPFELLQARQLLESEVAAFAAMQATKSDILKMRQ
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEQERLALNAGCADESADEQFHCLLAQSTQNSVLAGMVEDAWRARKHNPLWAGLHGHTQ
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCC
DFSYRWDWLEDHQRILQAVLRRDARDAKQAMWQHLENVKAKLLEISNPDDPGFDGYLFDS
CCCEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECC
TPVVLGDIAP
CCEEECCCCC
>Mature Secondary Structure
MRLYQEVGNTLRAAIARGDYSIGGRLPPERDIAEYFDVSRSVVREALIMLELEHLIDVRK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSGVYVVALPQNVSSPRVRNLDENTFGPFELLQARQLLESEVAAFAAMQATKSDILKMRQ
CCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIEQERLALNAGCADESADEQFHCLLAQSTQNSVLAGMVEDAWRARKHNPLWAGLHGHTQ
HHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCC
DFSYRWDWLEDHQRILQAVLRRDARDAKQAMWQHLENVKAKLLEISNPDDPGFDGYLFDS
CCCEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECC
TPVVLGDIAP
CCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]