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The map label for this gene is lolA

Identifier: 238920373

GI number: 238920373

Start: 2374874

End: 2375488

Strand: Reverse

Name: lolA

Synonym: NT01EI_2483

Alternate gene names: 238920373

Gene position: 2375488-2374874 (Counterclockwise)

Preceding gene: 238920374

Following gene: 238920372

Centisome position: 62.31

GC content: 57.89

Gene sequence:

>615_bases
ATGAAAAAGCTGTTAGTTGCGTGCTGCGTCGTTAGCGGCATGATGTCGGCCTCCGTTCTGGCGTCGCCGAGCAGCGATCT
GCAGGGACGTTTGAATAAGGTAAACAGTTTCCACGCCAGCTTTACCCAGACGGTCAGCACGGCGGACGGCACGCCGGTGC
AGCAGGGCGAGGGGGAGCTGTGGGTAAAACGCCCCAATTTGTTTAATTGGCATATGATTTCGCCGGATGAGAGCGTGCTG
GTGTCCGATGGCAAGACCCTGTGGTTTTATAACCCCTTCGTCGAGCAGGTGACCGCCACCTGGCTTAACCGCGCCACCGG
CAATACGCCGTTTATGCTGATCACCCGCAACGACGCCAGCGACTGGGCGCAGTATAACGTGACCCAGCAGGGGAATACCT
TCGATCTGGTGCCGAAGAGCGCCAAGAATAACCTGAAGAAGTTCACCATCAGCGTAATGCCTGACGGCACCATCAACGGC
TTTAGCGCCGTCGAGCAGGATGGCCAGCGCAGCGTCTATACGCTGAAGCGTCAGCAGAATGGCGCGGTGGATGCGGCCAA
GTTCCGCTTTACACCGCCGCCTGGTGTGACGCTGGACGATCAGCGTCAACAATAA

Upstream 100 bases:

>100_bases
CGCTCCACGGCCCTGCGTATAATCAACGGGTATTGTGACACCTGATCGCGGTATCGCGGCGGTCAGGCCCAATTTATTCT
TGCTTAAGGTAATCATACCG

Downstream 100 bases:

>100_bases
GGGGCGGAACCGCGACGTGAGCAATCTTTCCCTCGACTTCTCCCAGAATGCGTTTCAGCCGTTGGCCGCCCGGATGCGGC
CGGCGACGCTGGAGCAGTAC

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKKLLVACCVVSGMMSASVLASPSSDLQGRLNKVNSFHASFTQTVSTADGTPVQQGEGELWVKRPNLFNWHMISPDESVL
VSDGKTLWFYNPFVEQVTATWLNRATGNTPFMLITRNDASDWAQYNVTQQGNTFDLVPKSAKNNLKKFTISVMPDGTING
FSAVEQDGQRSVYTLKRQQNGAVDAAKFRFTPPPGVTLDDQRQQ

Sequences:

>Translated_204_residues
MKKLLVACCVVSGMMSASVLASPSSDLQGRLNKVNSFHASFTQTVSTADGTPVQQGEGELWVKRPNLFNWHMISPDESVL
VSDGKTLWFYNPFVEQVTATWLNRATGNTPFMLITRNDASDWAQYNVTQQGNTFDLVPKSAKNNLKKFTISVMPDGTING
FSAVEQDGQRSVYTLKRQQNGAVDAAKFRFTPPPGVTLDDQRQQ
>Mature_204_residues
MKKLLVACCVVSGMMSASVLASPSSDLQGRLNKVNSFHASFTQTVSTADGTPVQQGEGELWVKRPNLFNWHMISPDESVL
VSDGKTLWFYNPFVEQVTATWLNRATGNTPFMLITRNDASDWAQYNVTQQGNTFDLVPKSAKNNLKKFTISVMPDGTING
FSAVEQDGQRSVYTLKRQQNGAVDAAKFRFTPPPGVTLDDQRQQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=203, Percent_Identity=67.9802955665025, Blast_Score=298, Evalue=1e-82,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_EDWI9 (C5BE92)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933888.1
- GeneID:   7958821
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2483
- OMA:   VDIDDQR
- ProtClustDB:   PRK00031
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 22569; Mature: 22569

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLVACCVVSGMMSASVLASPSSDLQGRLNKVNSFHASFTQTVSTADGTPVQQGEGEL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
WVKRPNLFNWHMISPDESVLVSDGKTLWFYNPFVEQVTATWLNRATGNTPFMLITRNDAS
EEECCCEEEEEEECCCCEEEEECCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCCC
DWAQYNVTQQGNTFDLVPKSAKNNLKKFTISVMPDGTINGFSAVEQDGQRSVYTLKRQQN
CHHEEEECCCCCEEEECCCHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCEEEEEECCC
GAVDAAKFRFTPPPGVTLDDQRQQ
CCCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MKKLLVACCVVSGMMSASVLASPSSDLQGRLNKVNSFHASFTQTVSTADGTPVQQGEGEL
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCE
WVKRPNLFNWHMISPDESVLVSDGKTLWFYNPFVEQVTATWLNRATGNTPFMLITRNDAS
EEECCCEEEEEEECCCCEEEEECCCEEEEECHHHHHHHHHHHHHCCCCCCEEEEECCCCC
DWAQYNVTQQGNTFDLVPKSAKNNLKKFTISVMPDGTINGFSAVEQDGQRSVYTLKRQQN
CHHEEEECCCCCEEEECCCHHCCCCEEEEEEEECCCCCCCHHHHHCCCCCCEEEEEECCC
GAVDAAKFRFTPPPGVTLDDQRQQ
CCCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA