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The map label for this gene is dmsB [H]

Identifier: 238920366

GI number: 238920366

Start: 2367223

End: 2367840

Strand: Reverse

Name: dmsB [H]

Synonym: NT01EI_2476

Alternate gene names: 238920366

Gene position: 2367840-2367223 (Counterclockwise)

Preceding gene: 238920367

Following gene: 238920365

Centisome position: 62.11

GC content: 63.11

Gene sequence:

>618_bases
ATGACAACGCAATACGGTTTTTATATCGACTCCAGCCGCTGCACCGGGTGTAAGACCTGCGAGCTGGCCTGTAAGGATTA
CAAGGATCTGACGCCGGACGTCAGCTTCCGCCGCATCTATGAGTACGCCGGCGGCGAGTGGCAGCGCGAGGGCGACGGCT
GGCATCATGACGTGTTTGCCTACTATCTCTCGATCTCCTGCAACCACTGCGACGACCCCGCCTGCGTGAAGGTGTGCCCG
AGCGGCGCGATGCACAAGCGGGAGGACGGCTTTGTGGTGGTGGACGAATCGGTGTGCATCGGCTGCCGCTATTGCCACAT
GGCCTGTCCCTACGGCGCGCCGCAGTACAATGCGCAGAAGGGGCATATGACCAAGTGCGATGGCTGCTATGAGCGGGTGG
CGCAGGGGCAGAAGCCGATCTGCGTCGAGTCTTGTCCGCTGCGTGCGCTCGATATGGGGCCGATCGCGGAGCTGCGTGCC
CGCCACGGTGATCTGGCCGCGGTAGCGCCGCTGCCGGCGGCGCACTATACCCGGCCGAACCTGGTGCTGAAGCCGAATGC
CAACAGCCGTCCGGTTGGTGATACCTGCGGCTACCTGGCAAATCCAAAGGAGGTCTGA

Upstream 100 bases:

>100_bases
TGTATTAACGTCCTGACGACTCAGCGCCCGTCGCCGCTGGCCAAGGGGAATCCGTCACACACCAATCTGGTACAGGTTGC
CAAGGCCTAAGGAGTCGCTG

Downstream 100 bases:

>100_bases
GATGGGAATGGGATGGCATGAATGGCCGTTGATGATCTTCACGGTGCTGGGGCAGAGCGTGGCCGGTGCCTTTATCGTGA
TGGCGGCGGTACTGCTGCGC

Product: dimethylsulfoxide reductase, chain B

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTTQYGFYIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGEWQREGDGWHHDVFAYYLSISCNHCDDPACVKVCP
SGAMHKREDGFVVVDESVCIGCRYCHMACPYGAPQYNAQKGHMTKCDGCYERVAQGQKPICVESCPLRALDMGPIAELRA
RHGDLAAVAPLPAAHYTRPNLVLKPNANSRPVGDTCGYLANPKEV

Sequences:

>Translated_205_residues
MTTQYGFYIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGEWQREGDGWHHDVFAYYLSISCNHCDDPACVKVCP
SGAMHKREDGFVVVDESVCIGCRYCHMACPYGAPQYNAQKGHMTKCDGCYERVAQGQKPICVESCPLRALDMGPIAELRA
RHGDLAAVAPLPAAHYTRPNLVLKPNANSRPVGDTCGYLANPKEV
>Mature_204_residues
TTQYGFYIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGEWQREGDGWHHDVFAYYLSISCNHCDDPACVKVCPS
GAMHKREDGFVVVDESVCIGCRYCHMACPYGAPQYNAQKGHMTKCDGCYERVAQGQKPICVESCPLRALDMGPIAELRAR
HGDLAAVAPLPAAHYTRPNLVLKPNANSRPVGDTCGYLANPKEV

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=205, Percent_Identity=85.8536585365854, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1787872, Length=205, Percent_Identity=83.9024390243902, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1787749, Length=159, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790326, Length=180, Percent_Identity=31.6666666666667, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1789370, Length=195, Percent_Identity=35.3846153846154, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI226510944, Length=152, Percent_Identity=37.5, Blast_Score=94, Evalue=5e-21,
Organism=Escherichia coli, GI2367345, Length=188, Percent_Identity=33.5106382978723, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787740, Length=107, Percent_Identity=42.0560747663551, Blast_Score=90, Evalue=9e-20,
Organism=Escherichia coli, GI1787478, Length=99, Percent_Identity=43.4343434343434, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI2367245, Length=166, Percent_Identity=33.7349397590361, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1789067, Length=180, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI87082179, Length=161, Percent_Identity=31.6770186335404, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787963, Length=149, Percent_Identity=30.2013422818792, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788811, Length=154, Percent_Identity=30.5194805194805, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082180, Length=192, Percent_Identity=28.125, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1789079, Length=193, Percent_Identity=28.4974093264249, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 22703; Mature: 22572

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

8.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
10.7 %Cys+Met (Translated Protein)
8.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
10.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQYGFYIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGEWQREGDGWHHDVFA
CCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEECCCCCHHHEEE
YYLSISCNHCDDPACVKVCPSGAMHKREDGFVVVDESVCIGCRYCHMACPYGAPQYNAQK
EEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEECCEEEEEHHHEEECCCCCCCCCCCC
GHMTKCDGCYERVAQGQKPICVESCPLRALDMGPIAELRARHGDLAAVAPLPAAHYTRPN
CCCCCHHHHHHHHHCCCCCEEECCCCCCEECCCCHHHHHHCCCCEEEECCCCCCCCCCCC
LVLKPNANSRPVGDTCGYLANPKEV
EEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTQYGFYIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAGGEWQREGDGWHHDVFA
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEECCCCCHHHEEE
YYLSISCNHCDDPACVKVCPSGAMHKREDGFVVVDESVCIGCRYCHMACPYGAPQYNAQK
EEEEEECCCCCCCCEEEECCCCCCCCCCCCEEEEECCEEEEEHHHEEECCCCCCCCCCCC
GHMTKCDGCYERVAQGQKPICVESCPLRALDMGPIAELRARHGDLAAVAPLPAAHYTRPN
CCCCCHHHHHHHHHCCCCCEEECCCCCCEECCCCHHHHHHCCCCEEEECCCCCCCCCCCC
LVLKPNANSRPVGDTCGYLANPKEV
EEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]