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The map label for this gene is kdsB

Identifier: 238920337

GI number: 238920337

Start: 2338204

End: 2338965

Strand: Reverse

Name: kdsB

Synonym: NT01EI_2447

Alternate gene names: 238920337

Gene position: 2338965-2338204 (Counterclockwise)

Preceding gene: 238920338

Following gene: 238920336

Centisome position: 61.35

GC content: 61.02

Gene sequence:

>762_bases
ATGAGTTTTATTGCTATTATCCCATCCCGATATGCATCGACCCGTCTGCCGGGGAAGCCGCTGGCGGACATCGCCGGTAA
ACCCATGGTGGTACATGTGATGGCCCAGGCCCAGGCCTCCGGCGCGGAGCGGGTCATTGTGGCGACCGATCACCCTGATG
TACAGCACGCCGTGCTGCAGGCGGGGGGCGAGGTGTGTATGACGCGCGCCGACCATAATTCGGGGACTGAACGGCTGGCC
GAGGTGGTTGAGCTCTGCGGCTTTGCTGATGACGACATCATCGTCAACGTACAGGGTGATGAGCCGCTGATCCCGCCGCA
GATTATTCGTCAGGTGGCTGAAAACCTGGCACGCTGTGACGCCGGTATGGCGACGCTGGCTGTGCCGATCCACGACGCCG
CTGAAGCCTTTAACCCCAATGCGGTGAAGGTGGTGCGTGACAGCCAGGGGTATGCGCTCTATTTCTCTCGCGCTGCCATT
CCCTGGGATCGCGAGCGCTTTGCTGTCTCGCAGAGCCAGATCGGGCAAACGTTTCTGCGTCACATCGGTATTTATGCCTA
TCGCGCCGGTTTTATCCGCCGCTATGTGAACTGGGCGCCCAGCCAGCTTGAGCAGATTGAGATGCTGGAGCAGTTGCGGG
TGCTGTGGTACGGCGAGAAGATCCACGTGGACGTCGCGCTGCAGGCGCCGGGCACCGGGGTAGACACTCCAGAGGATCTG
GACTGTGTACGGGCGATCCTGGCATCGCAGGGACAGAACTGA

Upstream 100 bases:

>100_bases
AGCTCGTCTGTAAAATTGACCGTTTGGCCTTTCCGCTGCGTGACGGCATCCCCGTGATGCTGGAAAGCGAGGCCCGACCC
TTGCCGCAGGAAGAGAATTG

Downstream 100 bases:

>100_bases
CCGCGTTTGTGGTGATATGAGTCGAAGTGAAAGCGTGCTATTGCACGCTTTTTTTGATCTTAGCGCGTGTGGAGGTGCGC
ATTCTCGCCCATGATAAAGT

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSFIAIIPSRYASTRLPGKPLADIAGKPMVVHVMAQAQASGAERVIVATDHPDVQHAVLQAGGEVCMTRADHNSGTERLA
EVVELCGFADDDIIVNVQGDEPLIPPQIIRQVAENLARCDAGMATLAVPIHDAAEAFNPNAVKVVRDSQGYALYFSRAAI
PWDRERFAVSQSQIGQTFLRHIGIYAYRAGFIRRYVNWAPSQLEQIEMLEQLRVLWYGEKIHVDVALQAPGTGVDTPEDL
DCVRAILASQGQN

Sequences:

>Translated_253_residues
MSFIAIIPSRYASTRLPGKPLADIAGKPMVVHVMAQAQASGAERVIVATDHPDVQHAVLQAGGEVCMTRADHNSGTERLA
EVVELCGFADDDIIVNVQGDEPLIPPQIIRQVAENLARCDAGMATLAVPIHDAAEAFNPNAVKVVRDSQGYALYFSRAAI
PWDRERFAVSQSQIGQTFLRHIGIYAYRAGFIRRYVNWAPSQLEQIEMLEQLRVLWYGEKIHVDVALQAPGTGVDTPEDL
DCVRAILASQGQN
>Mature_252_residues
SFIAIIPSRYASTRLPGKPLADIAGKPMVVHVMAQAQASGAERVIVATDHPDVQHAVLQAGGEVCMTRADHNSGTERLAE
VVELCGFADDDIIVNVQGDEPLIPPQIIRQVAENLARCDAGMATLAVPIHDAAEAFNPNAVKVVRDSQGYALYFSRAAIP
WDRERFAVSQSQIGQTFLRHIGIYAYRAGFIRRYVNWAPSQLEQIEMLEQLRVLWYGEKIHVDVALQAPGTGVDTPEDLD
CVRAILASQGQN

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=245, Percent_Identity=76.734693877551, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_EDWI9 (C5BAD7)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002933852.1
- GeneID:   7959179
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_2447
- OMA:   FSRAPLP
- ProtClustDB:   PRK05450
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 27669; Mature: 27538

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIAIIPSRYASTRLPGKPLADIAGKPMVVHVMAQAQASGAERVIVATDHPDVQHAVLQ
CCEEEEECCCHHCCCCCCCCHHHHCCCCEEEEEEEHHCCCCCCEEEEECCCCCHHHHHHH
AGGEVCMTRADHNSGTERLAEVVELCGFADDDIIVNVQGDEPLIPPQIIRQVAENLARCD
CCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHC
AGMATLAVPIHDAAEAFNPNAVKVVRDSQGYALYFSRAAIPWDRERFAVSQSQIGQTFLR
CCCEEEEEECHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HIGIYAYRAGFIRRYVNWAPSQLEQIEMLEQLRVLWYGEKIHVDVALQAPGTGVDTPEDL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCEEEEEEEEECCCCCCCCCCHH
DCVRAILASQGQN
HHHHHHHHHCCCC
>Mature Secondary Structure 
SFIAIIPSRYASTRLPGKPLADIAGKPMVVHVMAQAQASGAERVIVATDHPDVQHAVLQ
CEEEEECCCHHCCCCCCCCHHHHCCCCEEEEEEEHHCCCCCCEEEEECCCCCHHHHHHH
AGGEVCMTRADHNSGTERLAEVVELCGFADDDIIVNVQGDEPLIPPQIIRQVAENLARCD
CCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHC
AGMATLAVPIHDAAEAFNPNAVKVVRDSQGYALYFSRAAIPWDRERFAVSQSQIGQTFLR
CCCEEEEEECHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
HIGIYAYRAGFIRRYVNWAPSQLEQIEMLEQLRVLWYGEKIHVDVALQAPGTGVDTPEDL
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCEEEEEEEEECCCCCCCCCCHH
DCVRAILASQGQN
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA