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The map label for this gene is lolE [H]

Identifier: 238920220

GI number: 238920220

Start: 2227608

End: 2228855

Strand: Reverse

Name: lolE [H]

Synonym: NT01EI_2329

Alternate gene names: 238920220

Gene position: 2228855-2227608 (Counterclockwise)

Preceding gene: 238920221

Following gene: 238920219

Centisome position: 58.46

GC content: 63.46

Gene sequence:

>1248_bases
ATGGATCTGGCGCTCGCATTACACATCGCGCGCCGCTTCAGCCGCGGGCGGCGCAGGGGCGGCATGGTGTCGCTGATCTC
GGTGATTTCAACGGTCGGTATTGCGCTCGGGGTGGCGGTGCTGATCGTCGGCCTCAGCGCGATGAACGGATTTGAGCGCG
AGCTGGATCAGCGCATCCTGTCGGTGGTGCCGCACGGCGAGATCTACCCGGTGGAGCAGCCCTTTACTGACTGGCAGTCG
GTGCTGGCACGCGTCGATCGGGTGAAGGACGTGGTCGGCGCGGCGCCCTACGTTAACTTTACCGGGCTGATGGAGCACGG
CAGCCAGTTGCGCGCGGTACAGGTACGCGGGGTGGATCCCGCCCAGGAGAGCCGGGTTAGCTCCCTGCCGCGCTATGTTC
TGGATAACGCCTGGGTGGACTTTCACGCCGGCGGACAGCAGGTGATCCTGGGCAAGGGGGTCGCCGATGCGCTGGGCGTC
CGGCGCGGAGACTGGGTGACGGTGATGGTGCCCAACAGCGATCCGCAGATGAAGTTGCTGCAGCCCAAGCGCATTCGGCT
GCAGGTGGGGGGCATTCTGCAGCTGAGTGGGATGTTGGACCATACCCTGGCGTTGGTTCCCCTGGCCGATGCCCAGCAGT
ATCAGGATCTGGGCGACAGTGTGACCGGGATAGCCATCAGGGTTGCCGATCCGTTCCAGGCCGACAAAGTGGTGCGCGCG
GCGGGAGAGGTGACCAACGACTACGTCTACATCCGCAGCTGGAAAGGTACCTATGGCTATATGTTCCGCGATATTCAGAT
GATCCGCGTAATCATGTATCTGGCCATGGTGCTGGTGATCGGCGTCGCCTGTTTCAATATCGTCTCGACCCTGGTGATGG
CGGTGAAGGACAAGAGCAGTGATATCGCCGTGCTGCGTACGCTGGGCGCCCGGGATGGACTGATCCGCGCCATCTTTATC
TGGTATGGACTGCTCTCCGGGCTGGTGGGCAGCCTGTGCGGGGTGGCTATCGGCGTCGCGGCGTCGCTGAAGCTGACGCT
GATTGGCCGCCTCATTGAGCGCCTGCTGGGACATCGCCTGCTCTCGGGTGATATCTATCCAATCGACTTCCTGCCCAGTC
AGCTGCAGTGGAGCGATGTACTGGCGGTGCTGCTGACGGCTATCGTGCTGAGTCTGCTGGCCAGCTGGTATCCGGCGCGG
CGCGCCAGCCGTATCGACCCTGCGCGGGTGTTGAGCGGCGGTCAGTGA

Upstream 100 bases:

>100_bases
TGGTGACGCACGATCTGGCCCTGGCGGGCCGTCTGCGCCGCCAGTTGGAGATGCGTGACGGTCAGCTGACCCAGGAGCTG
ACGCTGATGGAGACTCGCTG

Downstream 100 bases:

>100_bases
TGGGGGCGTCGATGTATTACGGTTTCGATCTCGGCGGCAGTAAGCTGGCGCTGGGAGTGTATGATGAGAGTCTGAGCCGG
GTCGGCTACCGGCGCGTGGC

Product: outer membrane-specific lipoprotein transporter subunit LolE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MDLALALHIARRFSRGRRRGGMVSLISVISTVGIALGVAVLIVGLSAMNGFERELDQRILSVVPHGEIYPVEQPFTDWQS
VLARVDRVKDVVGAAPYVNFTGLMEHGSQLRAVQVRGVDPAQESRVSSLPRYVLDNAWVDFHAGGQQVILGKGVADALGV
RRGDWVTVMVPNSDPQMKLLQPKRIRLQVGGILQLSGMLDHTLALVPLADAQQYQDLGDSVTGIAIRVADPFQADKVVRA
AGEVTNDYVYIRSWKGTYGYMFRDIQMIRVIMYLAMVLVIGVACFNIVSTLVMAVKDKSSDIAVLRTLGARDGLIRAIFI
WYGLLSGLVGSLCGVAIGVAASLKLTLIGRLIERLLGHRLLSGDIYPIDFLPSQLQWSDVLAVLLTAIVLSLLASWYPAR
RASRIDPARVLSGGQ

Sequences:

>Translated_415_residues
MDLALALHIARRFSRGRRRGGMVSLISVISTVGIALGVAVLIVGLSAMNGFERELDQRILSVVPHGEIYPVEQPFTDWQS
VLARVDRVKDVVGAAPYVNFTGLMEHGSQLRAVQVRGVDPAQESRVSSLPRYVLDNAWVDFHAGGQQVILGKGVADALGV
RRGDWVTVMVPNSDPQMKLLQPKRIRLQVGGILQLSGMLDHTLALVPLADAQQYQDLGDSVTGIAIRVADPFQADKVVRA
AGEVTNDYVYIRSWKGTYGYMFRDIQMIRVIMYLAMVLVIGVACFNIVSTLVMAVKDKSSDIAVLRTLGARDGLIRAIFI
WYGLLSGLVGSLCGVAIGVAASLKLTLIGRLIERLLGHRLLSGDIYPIDFLPSQLQWSDVLAVLLTAIVLSLLASWYPAR
RASRIDPARVLSGGQ
>Mature_415_residues
MDLALALHIARRFSRGRRRGGMVSLISVISTVGIALGVAVLIVGLSAMNGFERELDQRILSVVPHGEIYPVEQPFTDWQS
VLARVDRVKDVVGAAPYVNFTGLMEHGSQLRAVQVRGVDPAQESRVSSLPRYVLDNAWVDFHAGGQQVILGKGVADALGV
RRGDWVTVMVPNSDPQMKLLQPKRIRLQVGGILQLSGMLDHTLALVPLADAQQYQDLGDSVTGIAIRVADPFQADKVVRA
AGEVTNDYVYIRSWKGTYGYMFRDIQMIRVIMYLAMVLVIGVACFNIVSTLVMAVKDKSSDIAVLRTLGARDGLIRAIFI
WYGLLSGLVGSLCGVAIGVAASLKLTLIGRLIERLLGHRLLSGDIYPIDFLPSQLQWSDVLAVLLTAIVLSLLASWYPAR
RASRIDPARVLSGGQ

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=413, Percent_Identity=72.3970944309927, Blast_Score=580, Evalue=1e-167,
Organism=Escherichia coli, GI1787360, Length=418, Percent_Identity=29.1866028708134, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45206; Mature: 45206

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLALALHIARRFSRGRRRGGMVSLISVISTVGIALGVAVLIVGLSAMNGFERELDQRIL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SVVPHGEIYPVEQPFTDWQSVLARVDRVKDVVGAAPYVNFTGLMEHGSQLRAVQVRGVDP
HHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEEECCCC
AQESRVSSLPRYVLDNAWVDFHAGGQQVILGKGVADALGVRRGDWVTVMVPNSDPQMKLL
HHHHHHHHCHHHHHHCCCEEEECCCCEEEEECCHHHHHCCCCCCEEEEEECCCCCCEECC
QPKRIRLQVGGILQLSGMLDHTLALVPLADAQQYQDLGDSVTGIAIRVADPFQADKVVRA
CCCEEEEEECCEEEEHHHHHHHHHEEECCCHHHHHHCCCCCCEEEEEECCCCHHHHHHHH
AGEVTNDYVYIRSWKGTYGYMFRDIQMIRVIMYLAMVLVIGVACFNIVSTLVMAVKDKSS
HHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DIAVLRTLGARDGLIRAIFIWYGLLSGLVGSLCGVAIGVAASLKLTLIGRLIERLLGHRL
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LSGDIYPIDFLPSQLQWSDVLAVLLTAIVLSLLASWYPARRASRIDPARVLSGGQ
HCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHCCCCC
>Mature Secondary Structure
MDLALALHIARRFSRGRRRGGMVSLISVISTVGIALGVAVLIVGLSAMNGFERELDQRIL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SVVPHGEIYPVEQPFTDWQSVLARVDRVKDVVGAAPYVNFTGLMEHGSQLRAVQVRGVDP
HHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCEEEEEEECCCC
AQESRVSSLPRYVLDNAWVDFHAGGQQVILGKGVADALGVRRGDWVTVMVPNSDPQMKLL
HHHHHHHHCHHHHHHCCCEEEECCCCEEEEECCHHHHHCCCCCCEEEEEECCCCCCEECC
QPKRIRLQVGGILQLSGMLDHTLALVPLADAQQYQDLGDSVTGIAIRVADPFQADKVVRA
CCCEEEEEECCEEEEHHHHHHHHHEEECCCHHHHHHCCCCCCEEEEEECCCCHHHHHHHH
AGEVTNDYVYIRSWKGTYGYMFRDIQMIRVIMYLAMVLVIGVACFNIVSTLVMAVKDKSS
HHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DIAVLRTLGARDGLIRAIFIWYGLLSGLVGSLCGVAIGVAASLKLTLIGRLIERLLGHRL
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LSGDIYPIDFLPSQLQWSDVLAVLLTAIVLSLLASWYPARRASRIDPARVLSGGQ
HCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10783239 [H]