Click here to switch to the map view.

The map label for this gene is ziaR [H]

Identifier: 238919870

GI number: 238919870

Start: 1902165

End: 1902473

Strand: Direct

Name: ziaR [H]

Synonym: NT01EI_1974

Alternate gene names: 238919870

Gene position: 1902165-1902473 (Clockwise)

Preceding gene: 238919869

Following gene: 238919871

Centisome position: 49.9

GC content: 58.58

Gene sequence:

>309_bases
ATGTTAATCGTCGCTGAAAGCACCATCTCTGAGCTGGCCGATATTTTCCGTCTCTTGGGTGATACCACCCGGCTACGCAT
TACGCTGTGCTGTCGGGCGCATCCCATTGCCGTCGGCGATATTGCCGCTTCGCTGGATATCAGCCCATCGCTGGTCAGTC
ACCATCTTCGCCTTCTCCGCGCCGCCCGGATAGTGACGGCCGATCGCCAGGGTAAACAGGTGTTCTACTTCGTGTCGGAC
TCGCATATCTCCCGGATGGTGGCCAGCATGCTGGAGCATCTGGATGAGCCGCGCCTGGATCTCGACTGA

Upstream 100 bases:

>100_bases
CCTAGCGCATCCTAAATTCACCTCCTGATGATTCGTCATATTGACAATGCTATCAACTGGAAATAACATATAAACATATA
TTCATTTGTTGGTATTTATG

Downstream 100 bases:

>100_bases
GGACGCGCGGCCTCGCCCCCCCCTTCTATCTTCGCCAATCCAGGATCTTTATGCCATGAATCAACCACAGTACATGCCGT
TTTCACGGGGCCCCAGTGCG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MLIVAESTISELADIFRLLGDTTRLRITLCCRAHPIAVGDIAASLDISPSLVSHHLRLLRAARIVTADRQGKQVFYFVSD
SHISRMVASMLEHLDEPRLDLD

Sequences:

>Translated_102_residues
MLIVAESTISELADIFRLLGDTTRLRITLCCRAHPIAVGDIAASLDISPSLVSHHLRLLRAARIVTADRQGKQVFYFVSD
SHISRMVASMLEHLDEPRLDLD
>Mature_102_residues
MLIVAESTISELADIFRLLGDTTRLRITLCCRAHPIAVGDIAASLDISPSLVSHHLRLLRAARIVTADRQGKQVFYFVSD
SHISRMVASMLEHLDEPRLDLD

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11366; Mature: 11366

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIVAESTISELADIFRLLGDTTRLRITLCCRAHPIAVGDIAASLDISPSLVSHHLRLLR
CEEEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHH
AARIVTADRQGKQVFYFVSDSHISRMVASMLEHLDEPRLDLD
HHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLIVAESTISELADIFRLLGDTTRLRITLCCRAHPIAVGDIAASLDISPSLVSHHLRLLR
CEEEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHH
AARIVTADRQGKQVFYFVSDSHISRMVASMLEHLDEPRLDLD
HHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]