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The map label for this gene is folM [H]

Identifier: 238919850

GI number: 238919850

Start: 1882973

End: 1883584

Strand: Reverse

Name: folM [H]

Synonym: NT01EI_1953

Alternate gene names: 238919850

Gene position: 1883584-1882973 (Counterclockwise)

Preceding gene: 238919854

Following gene: 238919848

Centisome position: 49.41

GC content: 59.97

Gene sequence:

>612_bases
ATGGATACGCTGTCCATGCCGCCGGTGGTGATCACCGGCGGCGCCCGTCGCGTTGGACTGGCGCTGGCCCTCTCCCTGCT
TGCCAGAGAGCTCCCCGTACTGGTGGCCTATCGCAGTGAATACCCTGCCCTGGCATCGCTGCGTCAGGCCGGGGCTCGCT
GCCTACGGTGTGATTTTTCTACGACAGAGGGGATCTATGATTTCGCCGCGCAGGTGCAGCGGATCACGCCTCACCTGCGG
GCACTGATACACAACGCCAGCGCCTGGCAGGCCGAGCGTCCCGATGTTGCACCGGAGCAGACACTCAATGCCATGTTACA
GATCCACGTTCATACGCCCTACCTGTTGAATCTGTTGCTGGAGCCTCTGTTGCGTGGACAGGGAGACGCAGGCGCCGATA
TCATCCATGTGACCGATTATGTCGTAGAGCGTGGCAGCGACAGCCATATCGCCTATGCAGCTGGTAAGGCTGCGCTGGAC
AATATGACGCGCTCCTTTGCCCGTAAGCTGGCTCCTGAGGTCAAGGTTAACGCCATCGCTCCGGCACTGATCCTGTTCAA
CCCGCAGGATGATGAGGCCTATCGGCAAAAAGCACTGGATAAGAGCCGCTAA

Upstream 100 bases:

>100_bases
GCATTTTAACGTTTACGGTACATATCCCGTGCGTCAATGGATACGCTGAACCGTAACGGTATCGCACAGCCGATACTTTT
TTCAGTTAAGGAAATTGCAG

Downstream 100 bases:

>100_bases
CAAAACCGTTCAACAAAGCGCAAGCAGATAACAGCACAAGCCAGCGTCAGCAAGGCAAGATGGGTATCCAGCCGCCGTTC
GAAGCGAATACGCAGCTTGC

Product: hypothetical protein

Products: NA

Alternate protein names: DHFR [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MDTLSMPPVVITGGARRVGLALALSLLARELPVLVAYRSEYPALASLRQAGARCLRCDFSTTEGIYDFAAQVQRITPHLR
ALIHNASAWQAERPDVAPEQTLNAMLQIHVHTPYLLNLLLEPLLRGQGDAGADIIHVTDYVVERGSDSHIAYAAGKAALD
NMTRSFARKLAPEVKVNAIAPALILFNPQDDEAYRQKALDKSR

Sequences:

>Translated_203_residues
MDTLSMPPVVITGGARRVGLALALSLLARELPVLVAYRSEYPALASLRQAGARCLRCDFSTTEGIYDFAAQVQRITPHLR
ALIHNASAWQAERPDVAPEQTLNAMLQIHVHTPYLLNLLLEPLLRGQGDAGADIIHVTDYVVERGSDSHIAYAAGKAALD
NMTRSFARKLAPEVKVNAIAPALILFNPQDDEAYRQKALDKSR
>Mature_203_residues
MDTLSMPPVVITGGARRVGLALALSLLARELPVLVAYRSEYPALASLRQAGARCLRCDFSTTEGIYDFAAQVQRITPHLR
ALIHNASAWQAERPDVAPEQTLNAMLQIHVHTPYLLNLLLEPLLRGQGDAGADIIHVTDYVVERGSDSHIAYAAGKAALD
NMTRSFARKLAPEVKVNAIAPALILFNPQDDEAYRQKALDKSR

Specific function: Catalyzes the reduction of dihydrofolate to tetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FolM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787891, Length=195, Percent_Identity=64.1025641025641, Blast_Score=259, Evalue=6e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.5.1.3 [H]

Molecular weight: Translated: 22206; Mature: 22206

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLSMPPVVITGGARRVGLALALSLLARELPVLVAYRSEYPALASLRQAGARCLRCDFS
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHCHHEEECCCC
TTEGIYDFAAQVQRITPHLRALIHNASAWQAERPDVAPEQTLNAMLQIHVHTPYLLNLLL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEECCHHHHHHHH
EPLLRGQGDAGADIIHVTDYVVERGSDSHIAYAAGKAALDNMTRSFARKLAPEVKVNAIA
HHHHCCCCCCCCCEEHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCHHEEC
PALILFNPQDDEAYRQKALDKSR
CEEEEECCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MDTLSMPPVVITGGARRVGLALALSLLARELPVLVAYRSEYPALASLRQAGARCLRCDFS
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHCHHEEECCCC
TTEGIYDFAAQVQRITPHLRALIHNASAWQAERPDVAPEQTLNAMLQIHVHTPYLLNLLL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHEEECCHHHHHHHH
EPLLRGQGDAGADIIHVTDYVVERGSDSHIAYAAGKAALDNMTRSFARKLAPEVKVNAIA
HHHHCCCCCCCCCEEHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCHHEEC
PALILFNPQDDEAYRQKALDKSR
CEEEEECCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA