Click here to switch to the map view.

The map label for this gene is apt [H]

Identifier: 238919794

GI number: 238919794

Start: 1827328

End: 1827894

Strand: Reverse

Name: apt [H]

Synonym: NT01EI_1898

Alternate gene names: 238919794

Gene position: 1827894-1827328 (Counterclockwise)

Preceding gene: 238919795

Following gene: 238919793

Centisome position: 47.95

GC content: 32.28

Gene sequence:

>567_bases
ATGCTTCTTGAGGAAATTTATACGAATGCTAAAGTTGTTAAATCAGGCCGTATGTTAACAACCGTTAATGAATTTAGCGA
CCAGTTACCAGCACTTAGACCTATTGTTTTAATTGAGATAGCTTATCAAGTTATTAAATATATAAATATTAGCTTTGATA
AAATCGTCACCGAGGAGGATAAAGGTGCGCCATTAGCTACTACGATATCTCTGTTGACTGGAAAACCTCTTGCAATGGCT
CGCTGGTATCCATATAGCCTCAATGAATATAATAAAAATGTTGTAAAAATTTCCTCAGAGTACTTTGATGGAAATATATA
TCTAAATGGCATAAATAAAAATGATAGGGTGGTTATTATTGATGATACAATAAGCACTGGCGGCACAGTTATTTCTTTAA
TAAAAGCAATAGAAAATGCTGGAGGTATAGTGGAGAGAGTAATATGTGTTGTCGAAAAATCGCAAAACAATGGAAGAATC
AACGTAAAAGAGGAAACAGGTCATGATATTATATCGATAGTAAAAATAAAGATTGATGATAATAAAGTAACCATTATCGA
TAACTAA

Upstream 100 bases:

>100_bases
AATAAAGTAATCATAACAATTTTCTTCGACAGCTCATGGAAATATAAGAGCCGATGGAATGGCATATATCCAGAATATAA
TATGTAAAATGGAGATCATC

Downstream 100 bases:

>100_bases
GAATAATAGCACCATCATGGACATTATACTGAAATCGCATGGATACTTTTATCAAAGGATAATCCAATGAGCACCAACGC
AGCATTTTCCGGCGTTAGTT

Product: adenine phosphoribosyltransferase

Products: NA

Alternate protein names: APRT [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MLLEEIYTNAKVVKSGRMLTTVNEFSDQLPALRPIVLIEIAYQVIKYINISFDKIVTEEDKGAPLATTISLLTGKPLAMA
RWYPYSLNEYNKNVVKISSEYFDGNIYLNGINKNDRVVIIDDTISTGGTVISLIKAIENAGGIVERVICVVEKSQNNGRI
NVKEETGHDIISIVKIKIDDNKVTIIDN

Sequences:

>Translated_188_residues
MLLEEIYTNAKVVKSGRMLTTVNEFSDQLPALRPIVLIEIAYQVIKYINISFDKIVTEEDKGAPLATTISLLTGKPLAMA
RWYPYSLNEYNKNVVKISSEYFDGNIYLNGINKNDRVVIIDDTISTGGTVISLIKAIENAGGIVERVICVVEKSQNNGRI
NVKEETGHDIISIVKIKIDDNKVTIIDN
>Mature_188_residues
MLLEEIYTNAKVVKSGRMLTTVNEFSDQLPALRPIVLIEIAYQVIKYINISFDKIVTEEDKGAPLATTISLLTGKPLAMA
RWYPYSLNEYNKNVVKISSEYFDGNIYLNGINKNDRVVIIDDTISTGGTVISLIKAIENAGGIVERVICVVEKSQNNGRI
NVKEETGHDIISIVKIKIDDNKVTIIDN

Specific function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis [H]

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005764
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.7 [H]

Molecular weight: Translated: 20947; Mature: 20947

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEEIYTNAKVVKSGRMLTTVNEFSDQLPALRPIVLIEIAYQVIKYINISFDKIVTEED
CCHHHHHCCCEEEECCCEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHEEECCC
KGAPLATTISLLTGKPLAMARWYPYSLNEYNKNVVKISSEYFDGNIYLNGINKNDRVVII
CCCCHHEEEHHHCCCCCCEEEECCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCEEEE
DDTISTGGTVISLIKAIENAGGIVERVICVVEKSQNNGRINVKEETGHDIISIVKIKIDD
ECCCCCCHHHHHHHHHHHCCCCHHHHHHEEEEECCCCCEEEEECCCCCCEEEEEEEEECC
NKVTIIDN
CEEEEEEC
>Mature Secondary Structure
MLLEEIYTNAKVVKSGRMLTTVNEFSDQLPALRPIVLIEIAYQVIKYINISFDKIVTEED
CCHHHHHCCCEEEECCCEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHEEECCC
KGAPLATTISLLTGKPLAMARWYPYSLNEYNKNVVKISSEYFDGNIYLNGINKNDRVVII
CCCCHHEEEHHHCCCCCCEEEECCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCEEEE
DDTISTGGTVISLIKAIENAGGIVERVICVVEKSQNNGRINVKEETGHDIISIVKIKIDD
ECCCCCCHHHHHHHHHHHCCCCHHHHHHEEEEECCCCCEEEEECCCCCCEEEEEEEEECC
NKVTIIDN
CEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA