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The map label for this gene is mdaB [H]

Identifier: 238919717

GI number: 238919717

Start: 1757339

End: 1757932

Strand: Reverse

Name: mdaB [H]

Synonym: NT01EI_1820

Alternate gene names: 238919717

Gene position: 1757932-1757339 (Counterclockwise)

Preceding gene: 238919718

Following gene: 238919715

Centisome position: 46.11

GC content: 58.92

Gene sequence:

>594_bases
ATGAGTCATATCCTATTGCTTAACGGCATGAAACCCTTCGGCCACTCGAACGGCCAGTTGAACACCACGCTACACGACAC
CGCCCAAGAGCACCTGGGCGAGCTGGGACACCAGCTGCGCGCGACGACGATCGCTGAGGGATACCAAGTAGCACAGGAGG
TGGAGAATCTCCTGTGGGCGGACTGCATCATCTATCAGATGCCGGGATGGTGGATGGGGGAACCCTGGATCGTCAAAAAA
TACCTTGATGAGGTCTTCACCGCCGGTCATGGCCGTCTGTACACCAACGATGGCCGTACCCGCGCCGACACCAGTAAAAA
ATATGGTTCCGGCGGACTGCTGCAGGACAAAAAATATATGCTGTCGCTAACCTGGAATGCGCCGCAGGAGGCCTTTGACG
ATCCGGCCCAGTTCTTCCACGGCCAGGGGATCGACGGCGTCTACCTGCACTTTCACAAGGCCAACCAGTTCCTCGGTATG
GCGCCCCTGCCGACCTTCCTGTGCACCGACGTCATCAAGCGGCCGGACGTCGAGCACAATGTGGCGCGCTACCGTGAGCA
CCTGACGCGCCTGTTCACCAACGGCACCTGCTGA

Upstream 100 bases:

>100_bases
CCCGCCGCGACGCGTTCCAATAGAGTAATCACAATGATAGTTTTATAAACATTCATTTACGTATCCGTCATGCTGCCCAT
CGGGCGCACTGGAGCCAGTC

Downstream 100 bases:

>100_bases
ATCCGGCGCAAAACACGGGGTGCCCCGCCCATCGCGCGACACCCCGGATACGACGGCCATCCCCGGCCGCCGTACAGCGG
TCCAGATTATCCGGCGACGC

Product: hypothetical protein

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSHILLLNGMKPFGHSNGQLNTTLHDTAQEHLGELGHQLRATTIAEGYQVAQEVENLLWADCIIYQMPGWWMGEPWIVKK
YLDEVFTAGHGRLYTNDGRTRADTSKKYGSGGLLQDKKYMLSLTWNAPQEAFDDPAQFFHGQGIDGVYLHFHKANQFLGM
APLPTFLCTDVIKRPDVEHNVARYREHLTRLFTNGTC

Sequences:

>Translated_197_residues
MSHILLLNGMKPFGHSNGQLNTTLHDTAQEHLGELGHQLRATTIAEGYQVAQEVENLLWADCIIYQMPGWWMGEPWIVKK
YLDEVFTAGHGRLYTNDGRTRADTSKKYGSGGLLQDKKYMLSLTWNAPQEAFDDPAQFFHGQGIDGVYLHFHKANQFLGM
APLPTFLCTDVIKRPDVEHNVARYREHLTRLFTNGTC
>Mature_196_residues
SHILLLNGMKPFGHSNGQLNTTLHDTAQEHLGELGHQLRATTIAEGYQVAQEVENLLWADCIIYQMPGWWMGEPWIVKKY
LDEVFTAGHGRLYTNDGRTRADTSKKYGSGGLLQDKKYMLSLTWNAPQEAFDDPAQFFHGQGIDGVYLHFHKANQFLGMA
PLPTFLCTDVIKRPDVEHNVARYREHLTRLFTNGTC

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=192, Percent_Identity=65.1041666666667, Blast_Score=270, Evalue=4e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 22393; Mature: 22261

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHILLLNGMKPFGHSNGQLNTTLHDTAQEHLGELGHQLRATTIAEGYQVAQEVENLLWA
CCEEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DCIIYQMPGWWMGEPWIVKKYLDEVFTAGHGRLYTNDGRTRADTSKKYGSGGLLQDKKYM
HHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEECCEEE
LSLTWNAPQEAFDDPAQFFHGQGIDGVYLHFHKANQFLGMAPLPTFLCTDVIKRPDVEHN
EEEECCCCHHHHCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHH
VARYREHLTRLFTNGTC
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SHILLLNGMKPFGHSNGQLNTTLHDTAQEHLGELGHQLRATTIAEGYQVAQEVENLLWA
CEEEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DCIIYQMPGWWMGEPWIVKKYLDEVFTAGHGRLYTNDGRTRADTSKKYGSGGLLQDKKYM
HHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEECCEEE
LSLTWNAPQEAFDDPAQFFHGQGIDGVYLHFHKANQFLGMAPLPTFLCTDVIKRPDVEHN
EEEECCCCHHHHCCHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHH
VARYREHLTRLFTNGTC
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]